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Disclosery

APLS APELLIS PHARMACEUTICALS INC

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COM (common)

313 managers (325 13F filers) reported a position in APLS shares at 2026-03-31, 140,379,751 shares in all. 116 filers opened a position and 78 filers sold out during the quarter.

Managers
313
13F filers
325
New
116
Added
91
Reduced
73
Sold out
78
Shares held by filers
140,379,751

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.13,536,964$545M0.01%+7,276,85113F-HRTimelineGroup
Avoro Capital Advisors LLC12,222,222$492M4.84%013F-HRTimeline
VANGUARD GROUP INCgroup of 6 filers holding10,960,265$441MnewTimeline
MORGAN STANLEYin group MORGAN STANLEY10,042,399$404M0.02%+869,39513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP6,844,990$275M0.01%+2,231,54413F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding6,386,634$257M+2,021,524Timeline
Pentwater Capital Management LP5,250,000$211M1.5%new13F-HRTimeline
Deep Track Capital, LP4,532,374$182M3.76%-3,217,62613F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.4,183,918$168M0.29%+3,586,24613F-HRTimelineGroup
RTW INVESTMENTS, LP3,685,045$148M1.48%-3,981,71913F-HRTimeline
HBK INVESTMENTS L P3,550,000$143M1.8%new13F-HRTimeline
MONTANOVA CAPITAL, LLC3,518,471$142M3.84%-620,95513F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC2,256,802$90.8M0.07%+1,310,34313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,075,075$83.5M0.01%+49,40613F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,980,144$79.7M0.01%+1,790,93913F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management1,917,501$77.1M0.15%+1,852,36813F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,338,995$53.7M0.01%+1,158,07013F-HRTimelineGroup
GLAZER CAPITAL, LLCin group GLAZER CAPITAL, LLC1,294,196$52.1M1.11%new13F-HRTimelineGroup
FIRST TRUST ADVISORS LPgroup of 2 filers holding1,254,437$50.5M+758,490Timeline
TIG Advisors, LLCin group TIG Advisors, LLC1,252,986$50.4M2.41%new13F-HRTimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK1,236,436$49.7M0.1%new13F-HRTimelineGroup
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…1,202,100$48.4M0.08%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,190,864$47.9M<0.01%+234,09113F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…1,190,416$47.9M0.29%+10,58813F-HRTimelineGroup
FIL Ltdin group FIL Ltd1,140,000$45.9M0.04%new13F-HRTimelineGroup
Kryger Capital LLC1,100,000$44.3M3.13%13F-HRTimeline
SOROS FUND MANAGEMENT LLCin group SOROS FUND MANAGEMENT LLC1,056,000$42.5M0.58%new13F-HRTimelineGroup
CAPITOLIS LIQUID GLOBAL MARKETS LLCin group CAPITOLIS LIQUID GLOBAL MARKE…1,013,500$40.8M0.26%13F-HRTimelineGroup
Woodline Partners LP976,175$39.3M0.15%+433,19413F-HR/ATimeline
RENAISSANCE TECHNOLOGIES LLC935,958$37.7M0.06%+302,90013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP929,019$37.4M0.04%-61,82913F-HRTimelineGroup
Man Group plcin group Man Group plc915,689$36.8M0.08%+771,41813F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,047,927$35M<0.01%+1,890,17313F-HR/ATimelineGroup
Magnetar Financial LLCin group Magnetar Financial LLC869,229$35M0.36%new13F-HRTimelineGroup
ALPINE ASSOCIATES MANAGEMENT INC.864,000$34.8M2.05%new13F-HRTimeline
ODDO BHF ASSET MANAGEMENT SAS825,000$33.2M1.31%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Kynam Capital Management, LP825,000$33.2M2.11%-83,60713F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP738,440$29.7M<0.01%+41,91913F-HRTimelineGroup
Weiss Asset Management LPin group Weiss Asset Management LP700,000$28.2M0.52%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co675,864$27.2M<0.01%+31,41913F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC657,223$26.4M0.02%+35,06513F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL650,000$26.1M0.14%+435,00013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS584,192$23.5M0.02%+26,60113F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCgroup of 2 filers holding574,574$23.1M-1,702,113Timeline
OSSIAM555,953$22.4M0.39%+124,17413F-HRTimeline
GAMCO Investors (Gabelli)group of 3 filers holding542,800$21.8MnewTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp524,789$21.1M<0.01%+252,86413F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP521,965$21M0.02%-40,39613F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC499,053$20.1M0.01%new13F-HRTimelineGroup
Absolute Gestao de Investimentos Ltda.450,000$18.1M2.07%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC449,796$18.1M0.04%+257,64013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.437,868$17.6M<0.01%+211,89213F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP403,622$16.2M0.15%new13F-HRTimelineGroup
Verition Fund Management LLC400,000$16.1M0.16%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.638,291$16M0.01%+603,76113F-HRTimeline
Public Sector Pension Investment Board366,674$14.8M0.05%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…340,086$13.7M0.02%-193,82313F-HRTimelineGroup
Beck Bode, LLC312,841$12.6M2.13%new13F-HRTimeline
Meteora Capital, LLC300,000$12.1M0.89%new13F-HRTimeline
O'Connor Alternative Investments LLC300,000$12.1M0.63%13F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC291,488$11.7M0.17%+97,61213F-HRTimelineGroup
RHUMBLINE ADVISERS275,540$11.1M0.01%+158,62313F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson252,130$10.1M<0.01%+21,81013F-HR/ATimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC250,000$10.1M0.93%-80,00013F-HRTimelineGroup
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…250,000$10.1M0.08%new13F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…249,635$10M<0.01%-12,471,71713F-HRTimelineGroup
Granite Investment Partners, LLC231,917$9.33M0.57%-95,17713F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc228,255$9.18M<0.01%+142,76613F-HRTimelineGroup
Westchester Capital Management, LLCin group Westchester Capital Managemen…227,489$9.15M0.44%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA220,114$8.86M<0.01%-461,70513F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.219,000$8.81M0.11%+210,28213F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/215,041$8.65M<0.01%+38,47013F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.214,914$8.65M1.49%-36,04713F-HRTimelineGroup
Trexquant Investment LP205,219$8.26M0.06%+10,62713F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…426,821$7.56M0.01%+35,93713F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.186,853$7.52M0.01%-262,82313F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC183,578$7.39M<0.01%-406,01913F-HR/ATimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC183,522$7.38M0.17%+162,10713F-HRTimeline
Rafferty Asset Management, LLC180,471$7.26M0.03%+9,01513F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co180,161$7.25M0.09%-9313F-HRTimelineGroup
GARDNER LEWIS ASSET MANAGEMENT L P165,000$6.64M1.44%new13F-HRTimeline
Rock Springs Capital Management LP162,750$6.55M0.39%+12,25013F-HRTimeline
MACKENZIE FINANCIAL CORP153,330$6.17M0.01%+57,11913F-HRTimeline
PICTON MAHONEY ASSET MANAGEMENT150,000$6.03M0.06%new13F-HRTimeline
Swiss National Bank149,500$6.01M<0.01%013F-HRTimeline
Empowered Funds, LLC148,038$5.96M0.04%+134,65713F-HR/ATimeline
Chicago Capital Management, LLC190,000$5.76M4.77%new13F-HRTimeline
Slotnik Capital, LLC135,000$5.43M1.61%new13F-HRTimeline
Twin Securities, Inc.127,440$5.13M2.53%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA126,701$5.1M<0.01%+38,01413F-HRTimelineGroup
Schonfeld Strategic Advisors LLC123,824$4.98M0.04%new13F-HRTimeline
Quantinno Capital Management LP121,270$4.88M0.01%+89,50713F-HRTimeline
WATER ISLAND CAPITAL LLC120,500$4.85M0.65%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC111,468$4.48M0.34%+72,94713F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/106,908$4.3M<0.01%+11,87313F-HRTimeline
Sagefield Capital LPin group Sagefield Capital LP104,065$4.19M0.3%new13F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC104,058$4.19M0.02%+36213F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC98,327$3.96M<0.01%-89,38513F-HRTimelineGroup
NINE MASTS CAPITAL Ltd97,478$3.92M0.61%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…96,125$3.87M0.01%013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\95,365$3.84M<0.01%-1,289,89813F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…94,833$3.82M<0.01%+21,63013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC92,510$3.72M<0.01%new13F-HRTimelineGroup
Caitong International Asset Management …90,466$3.64M0.67%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC85,913$3.46M0.01%-865,80313F-HRTimeline
Exome Asset Management LLC85,517$3.44M2.02%-50,33213F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP84,571$3.4M<0.01%new13F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND84,451$3.4M<0.01%-19,56713F-HRTimeline
ABC ARBITRAGE SAin group ABC ARBITRAGE SA83,317$3.35M0.45%new13F-HRTimelineGroup
PROFUND ADVISORS LLC81,190$3.27M0.12%+19,35813F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC80,956$3.26M0.06%new13F-HR/ATimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co80,662$3.25M0.01%+72,16713F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD79,680$3.21M0.01%+12,76413F-HRTimeline
Gotham Asset Management, LLC78,750$3.17M0.01%-89,70513F-HRTimeline
HGC Investment Management Inc.75,000$3.02M0.67%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC74,716$3M<0.01%-131,27013F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC72,500$2.92M0.18%+52,50013F-HRTimelineGroup
HARVEST MANAGEMENT LLC70,000$2.82M1.5%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd69,291$2.79M0.1%-17,36213F-HRTimelineGroup
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…68,407$2.75M0.01%new13F-HRTimelineGroup
CAPITAL FUND MANAGEMENT S.A.68,112$2.74M0.02%new13F-HRTimeline
FNY Investment Advisers, LLC63,092$2.54M1.11%new13F-HRTimeline
ExodusPoint Capital Management, LP62,989$2.53M0.03%-108,16713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC62,631$2.52M<0.01%-4,36613F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC61,681$2.48M0.01%new13F-HRTimeline
BURNEY CO/61,578$2.48M0.08%new13F-HRTimeline
IMC-Chicago, LLC59,232$2.38M0.04%+37,90813F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC56,801$2.29M0.02%+20,15413F-HRTimelineGroup
Capula Management Ltdin group Capula Management Ltd56,266$2.26M0.02%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
One68 Global Capital, LLC55,347$2.23M7.21%new13F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC54,785$2.2M0.09%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…54,474$2.19M<0.01%+94813F-HRTimelineGroup
PDT Partners, LLC53,951$2.17M0.13%013F-HRTimeline
Versor Investments LP51,146$2.06M5.04%new13F-HRTimeline
State of Alaska, Department of Revenue50,562$2.03M0.02%new13F-HRTimeline
Hennion & Walsh Asset Management, Inc.50,374$2.03M0.07%-1,55913F-HRTimeline
TPG GP A, LLCin group TPG GP A, LLC50,000$2.01M0.05%new13F-HRTimelineGroup
Elmind Capital, LP50,000$2.01M0.57%013F-HRTimeline
CIBRA Capital Ltd50,000$2.01M0.97%new13F-HRTimeline
Treasurer of the State of North Carolina46,153$1.86M0.01%+98313F-HRTimeline
Police & Firemen's Retirement System of…46,009$1.85M0.02%013F-HRTimeline
Louisiana State Employees Retirement Sy…45,400$1.83M0.03%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…44,757$1.8M<0.01%+34,75913F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC43,669$1.76M<0.01%+813F-HRTimelineGroup
CSS LLC/IL42,818$1.72M0.1%new13F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al41,665$1.68M0.01%+17,30013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd41,627$1.67M0.03%new13F-HRTimelineGroup
State of Tennessee, Department of Treas…40,180$1.62M0.01%new13F-HRTimeline
Fortress Investment Group LLCin group Fortress Investment Group LLC40,000$1.61M0.41%new13F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC38,887$1.56M<0.01%-609,34213F-HRTimelineGroup
Handelsbanken Fonder AB35,400$1.42M<0.01%013F-HRTimeline
Carmignac Gestion35,127$1.41M0.02%new13F-HRTimeline
Bridgewater Associates, LP34,913$1.4M0.01%-108,89213F-HRTimeline
AMALGAMATED BANK34,726$1.4M0.01%+25,99013F-HRTimeline
READYSTATE ASSET MANAGEMENT LP34,100$1.37M0.08%new13F-HRTimeline
DRW Securities, LLC33,573$1.35M0.07%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…33,462$1.35M0.37%+6,37613F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…31,378$1.26M<0.01%-1,07013F-HRTimeline
Odyssean, LLC31,032$1.25M0.46%+11,82513F-HRTimeline
Amundiin group Amundi30,721$1.24M<0.01%013F-HRTimelineGroup
Carlson Capital, L.P.30,000$1.21M0.48%new13F-HRTimeline
SG Americas Securities, LLC29,601$1.19M<0.01%-537,44513F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP28,220$1.14M<0.01%-8,44113F-HRTimelineGroup
YOUSIF CAPITAL MANAGEMENT, LLC27,997$1.13M0.01%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…27,921$1.12M<0.01%+2,55713F-HRTimeline
Jain Global LLC27,793$1.12M0.01%+10,91613F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…25,896$1.04M<0.01%+3313F-HRTimelineGroup
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…25,344$1.02M0.01%new13F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…25,000$1.01M0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …24,765$996K<0.01%+1,91313F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC23,779$957K0.11%new13F-HRTimeline
Transmarket Holdings LP23,585$949K0.51%new13F-HRTimeline
OREGON PUBLIC EMPLOYEES RETIREMENT FUND23,400$941K0.01%new13F-HRTimeline
E Fund Management Co., Ltd.22,686$913K0.03%13F-HRTimeline
China Universal Asset Management Co., L…22,684$913K0.07%+2,06713F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…22,102$889K<0.01%new13F-HRTimelineGroup
Mint Tower Capital Management B.V.22,000$885K0.08%new13F-HRTimeline
Maryland State Retirement & Pension Sys…20,816$837K0.02%new13F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM20,813$837K<0.01%-19713F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…20,634$830K<0.01%+20,13113F-HRTimelineGroup
JBF Capital, Inc.20,532$826K0.12%new13F-HRTimeline
SummitTX Capital, L.P.20,351$819K0.03%new13F-HRTimeline
Clear Harbor Asset Management, LLC20,000$805K0.06%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC19,817$797K<0.01%+4,62013F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD19,600$789K<0.01%-202,60013F-HRTimeline
Engineers Gate Manager LP19,197$772K0.01%new13F-HRTimeline
XPONANCE LLC18,550$746K0.01%+38613F-HRTimeline
NEW YORK STATE TEACHERS RETIREMENT SYST…18,299$736K<0.01%new13F-HRTimeline
Duncan Williams Asset Management, LLC17,005$684K0.19%013F-HRTimeline
KLP KAPITALFORVALTNING AS16,200$652K<0.01%013F-HRTimeline
Summit Trail Advisors, LLC16,023$645K0.01%+2,17213F-HRTimeline
GTS SECURITIES LLC15,604$628K0.02%new13F-HRTimeline
Vident Advisory, LLCin group Vident Advisory, LLC15,079$607K0.01%-47413F-HRTimelineGroup
Birchview Capital, LP14,000$563K0.32%013F-HRTimeline
denkapparat Operations GmbH13,334$536K0.22%new13F-HRTimeline
Dynasty Wealth Management, LLC13,321$536K<0.01%+4,09413F-HRTimeline
Bayesian Capital Management, LP13,104$527K0.64%new13F-HRTimeline
Blackstone Inc.in group Blackstone Inc.12,712$511K<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
AE Wealth Management LLC12,316$495K<0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding19,456$487K+3,264Timeline