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Disclosery

APLS APELLIS PHARMACEUTICALS INC

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COM (common)

254 managers (258 13F filers) reported a position in APLS shares at 2025-03-31, 127,996,413 shares in all. 47 filers opened a position and 51 filers sold out during the quarter.

Managers
254
13F filers
258
New
47
Added
90
Reduced
77
Sold out
51
Shares held by filers
127,996,413

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…12,303,252$269M0.05%+502,40313F-HRTimelineGroup
Avoro Capital Advisors LLC12,222,222$267M4.17%013F-HRTimeline
EcoR1 Capital, LLC11,895,808$260M15.46%+4,96513F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding10,130,356$222M+76,499Timeline
MORGAN STANLEYin group MORGAN STANLEY9,626,123$211M0.02%-1,10413F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.6,329,598$138M<0.01%-148,39113F-HRTimelineGroup
Deep Track Capital, LP5,000,000$109M3.54%+725,07913F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC4,077,419$89.2M0.09%+2,220,97713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,941,405$86.2M<0.01%-583,75013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding3,494,828$76.4M+695,202Timeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/3,131,436$68.5M0.01%+1,451,22313F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.2,578,396$56.4M3.18%-237,86213F-HR/ATimelineGroup
JENNISON ASSOCIATES LLC2,477,531$54.2M0.04%-282,87313F-HRTimeline
Octagon Capital Advisors LP2,094,000$45.8M9.01%-912,98013F-HR/ATimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,950,046$42.7M<0.01%+111,09413F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,776,576$38.9M0.02%-1,80113F-HRTimelineGroup
BRAIDWELL LP1,652,334$36.1M1.27%-446,53213F-HRTimeline
MONTANOVA CAPITAL, LLC1,646,615$36M1.46%+853,42813F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,577,175$34.5M0.21%013F-HRTimelineGroup
NORGES BANK1,573,601$34.4M<0.01%+487,35813F-HR/ATimeline
FMR LLCin group FMR LLC1,503,209$32.9M<0.01%-624,45613F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,432,300$31.3M0.75%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,110,709$24.3M0.02%+259,88613F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD1,048,700$22.9M0.02%+1,013,50013F-HRTimeline
Man Group plcin group Man Group plc1,027,792$22.5M0.07%+978,50013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co964,499$21.1M<0.01%-32,24913F-HR/ATimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA794,935$17.4M<0.01%-723,89213F-HR/ATimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/782,701$17.1M0.02%-602,89913F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC713,000$15.6M4.69%-713,00013F-HR/ATimelineGroup
NATIXISin group Natixis Investment Managers655,027$14.8M0.09%-215,60013F-HR/ATimelineGroup
Invesco Ltd.in group Invesco Ltd.641,397$14M<0.01%+37,74113F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.599,255$13.1M0.23%+257,89413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP518,694$11.3M<0.01%-28,58213F-HRTimelineGroup
Nuveen, LLCin group TIAA492,238$10.8M<0.01%13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC466,661$10.2M<0.01%-416,14013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding454,704$9.94MnewTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC451,973$9.88M0.01%-123,51713F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC442,793$9.68M0.02%+275,83113F-HR/ATimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO423,800$9.27M<0.01%+12,25113F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC416,619$9.11M0.01%+224,45813F-HRTimelineGroup
Trexquant Investment LP384,922$8.42M0.1%+181,91413F-HRTimeline
SG Americas Securities, LLC366,144$8.01M0.03%+313,74313F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…314,842$7.62M0.01%-33,01213F-HRTimelineGroup
Amundiin group Amundi329,582$7.42M<0.01%013F-HRTimelineGroup
ALGERT GLOBAL LLC338,613$7.41M0.18%+56,32813F-HR/ATimeline
683 Capital Management, LLCin group 683 Capital Management, LLC333,000$7.28M0.74%-27,00013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp329,173$7.2M<0.01%-5,24313F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management324,487$7.1M0.02%-419,70713F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC317,442$6.94M0.08%-77,38113F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…310,700$6.8M0.04%-34,30013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC307,709$6.73M<0.01%+64,74213F-HR/ATimelineGroup
IEQ CAPITAL, LLC291,858$6.38M0.05%+165,14813F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP253,109$6.14M0.01%+33,72613F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC265,593$5.81M0.09%new13F-HR/ATimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC256,092$5.6M0.01%+160,10713F-HR/ATimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC253,790$5.55M0.02%-92,09513F-HRTimeline
ExodusPoint Capital Management, LP250,414$5.48M0.07%new13F-HRTimeline
Edgestream Partners, L.P.241,287$5.28M0.18%+131,40413F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC224,096$4.9M<0.01%+111,67313F-HRTimelineGroup
Woodline Partners LP218,850$4.79M0.03%+29,37313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC217,880$4.77M0.01%+19,82013F-HRTimelineGroup
Aquatic Capital Management LLC215,876$4.72M0.12%+86,66713F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC215,152$4.71M<0.01%-347,11713F-HRTimeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD204,803$4.48M0.01%+3,73613F-HR/ATimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co203,336$4.45M0.06%-26,46513F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP199,209$4.36M<0.01%+173,56413F-HRTimelineGroup
PDT Partners, LLC195,165$4.27M0.3%+57,47113F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC191,237$4.18M<0.01%+31,67213F-HR/ATimelineGroup
ING GROEP NV184,200$4.03M0.03%new13F-HRTimeline
Schonfeld Strategic Advisors LLC181,400$3.97M0.03%new13F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.181,346$3.97M0.98%-24,90513F-HRTimelineGroup
Rafferty Asset Management, LLC180,134$3.94M0.02%-61,34013F-HRTimeline
Granahan Investment Management, LLC175,696$3.84M0.19%+21,27813F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK162,190$3.55M0.01%-834,86313F-HRTimelineGroup
Candriam S.C.A.159,054$3.48M0.02%-380,54813F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/158,573$3.47M<0.01%+77,58213F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.150,000$3.28M0.01%new13F-HRTimelineGroup
Swiss National Bank132,600$2.9M<0.01%-11,10013F-HRTimeline
Connor, Clark & Lunn Investment Managem…131,895$2.88M0.01%+118,41713F-HRTimeline
Old West Investment Management, LLC128,192$2.8M1.01%+14,56913F-HRTimeline
California Public Employees Retirement …126,706$2.77M<0.01%+4713F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC125,401$2.74M<0.01%+2,25013F-HR/ATimelineGroup
RHUMBLINE ADVISERS124,454$2.72M<0.01%-1,10613F-HR/ATimeline
Steward Partners Investment Advisory, L…122,175$2.67M0.02%+7,13013F-HRTimeline
Verition Fund Management LLC110,510$2.42M0.01%+60,10013F-HRTimeline
HighVista Strategies LLC108,714$2.38M0.92%013F-HRTimeline
CWM, LLCin group CWM, LLC98,258$2.15M0.01%+53,66313F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…91,818$2.01M<0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/90,700$1.98M<0.01%-267,87813F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD84,615$1.85M<0.01%+4,23313F-HRTimeline
Rock Springs Capital Management LP80,000$1.75M0.1%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc79,070$1.73M<0.01%-7,70113F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC75,000$1.64M0.53%+71,40613F-HRTimelineGroup
Assenagon Asset Management S.A.74,325$1.63M<0.01%+44,33213F-HRTimeline
Bleakley Financial Group, LLC73,137$1.6M0.05%-36813F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…70,159$1.53M<0.01%+36,56513F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…59,778$1.31M<0.01%-10,91013F-HRTimeline
DekaBank Deutsche Girozentrale55,000$1.29M<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…58,391$1.28M<0.01%+23813F-HRTimelineGroup
AlphaQuest LLC56,104$1.23M0.13%+38,91813F-HRTimeline
Baird Financial Group, Inc.in group Baird Financial Group, Inc.55,529$1.21M<0.01%+86413F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC54,444$1.19M<0.01%+7,77713F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL52,980$1.16M0.01%new13F-HRTimeline
Bayforest Capital Ltd52,338$1.14M0.5%+42,49913F-HR/ATimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC51,978$1.14M<0.01%+2,96313F-HRTimelineGroup
Treasurer of the State of North Carolina49,005$1.07M<0.01%+3,09013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND48,837$1.07M<0.01%013F-HR/ATimeline
T. Rowe Price Investment Management, In…47,713$1.04M<0.01%013F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG47,096$1.03M0.02%-13,25113F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH42,000$1.02M0.01%013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.44,912$982K<0.01%+13,57213F-HRTimeline
Hennion & Walsh Asset Management, Inc.44,166$966K0.04%+14,42613F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC43,717$956K<0.01%+15,76613F-HRTimelineGroup
Pallas Capital Advisors LLC42,534$930K0.04%+29,16513F-HRTimeline
Engineers Gate Manager LP42,172$922K0.02%new13F-HRTimeline
MACKENZIE FINANCIAL CORP41,533$908K<0.01%+5,17513F-HRTimeline
EFG Asset Management (North America) Co…39,363$861K0.14%-3,79413F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…38,988$853K0.08%-10,99813F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…38,903$851K<0.01%+32,79613F-HRTimelineGroup
Police & Firemen's Retirement System of…38,569$844K0.01%+1,02513F-HRTimeline
Focus Partners Wealthgroup of 2 filers holding38,450$841K+28,429Timeline
JANUS HENDERSON GROUP PLCin group Janus Henderson34,412$836K<0.01%013F-HRTimelineGroup
Bayesian Capital Management, LP37,900$829K0.14%new13F-HRTimeline
PROFUND ADVISORS LLC35,657$780K0.03%-8,66213F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC35,348$773K0.01%+2,74113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding33,759$769K+19,999Timeline
Gotham Asset Management, LLC34,285$750K0.01%+9,98613F-HRTimeline
Merit Financial Group, LLC33,762$738K0.01%+25,80613F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…32,975$721K<0.01%-2,89713F-HRTimeline
Handelsbanken Fonder AB30,600$669K<0.01%013F-HRTimeline
Voleon Capital Management LP30,191$660K0.05%new13F-HRTimeline
GROUP ONE TRADING LLC30,041$657K0.03%new13F-HRTimeline
Y-Intercept (Hong Kong) Ltd29,577$647K0.04%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…29,505$645K<0.01%+3,28813F-HRTimelineGroup
Ensign Peak Advisors, Inc29,397$643K<0.01%-49,70013F-HRTimeline
CAPTRUST FINANCIAL ADVISORS29,280$640K<0.01%+16,65113F-HRTimeline
Bridgefront Capital, LLC29,070$636K0.18%new13F-HRTimeline
Parallax Volatility Advisers, L.P.28,350$620K0.02%new13F-HRTimeline
Rhenman & Partners Asset Management AB28,250$618K0.07%-167,34113F-HRTimeline
Graham Capital Management, L.P.28,136$615K0.02%new13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC24,999$552K<0.01%-102,82913F-HRTimelineGroup
China Universal Asset Management Co., L…25,176$551K0.05%-1,20013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …24,937$545K<0.01%-27,96013F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al24,665$539K<0.01%13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC23,976$522K<0.01%+22,05213F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP23,574$516K<0.01%-61,92113F-HRTimelineGroup
Scientech Research LLC23,395$512K0.14%+9,06213F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC22,997$503K0.02%new13F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV21,762$476K<0.01%+9,12913F-HRTimeline
EASTERN BANK21,500$470K0.01%013F-HRTimeline
Duncan Williams Asset Management, LLC21,125$462K0.17%013F-HRTimeline
GWN SECURITIES INC.27,190$454K0.03%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…19,891$435K<0.01%-45713F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM19,539$427K<0.01%-1,66513F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…18,912$414K<0.01%013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE18,800$411K<0.01%013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS18,459$404K<0.01%-3,19013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC17,000$372K0.07%+2,00013F-HRTimelineGroup
111 Capital16,836$368K0.07%new13F-HRTimeline
E Fund Management Co., Ltd.16,835$368K0.02%-32713F-HRTimeline
PANAGORA ASSET MANAGEMENT INC16,701$365K<0.01%013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …16,159$353K<0.01%new13F-HRTimelineGroup
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.18,864$353K<0.01%013F-HRTimelineGroup
XPONANCE LLC16,097$352K<0.01%+2,02513F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.15,712$344K0.05%new13F-HRTimeline
Aigen Investment Management, LP15,621$342K0.05%new13F-HRTimeline
WOLVERINE TRADING, LLC13,428$326K0.01%+2,85213F-HRTimeline
Birchview Capital, LP14,000$306K0.27%013F-HRTimeline
Mariner, LLCin group Mariner, LLC13,004$284K<0.01%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS13,000$284K<0.01%-2,80013F-HRTimeline
DIVERSIFIED TRUST CO12,878$282K0.01%new13F-HRTimeline
Caption Management, LLC12,000$262K0.01%new13F-HRTimeline
Teza Capital Management LLC11,855$259K0.12%new13F-HRTimeline
Jain Global LLC11,719$256K0.01%new13F-HRTimeline
Compagnie Lombard Odier SCmA11,000$241K<0.01%013F-HRTimeline
Virtus Investment Advisers, LLCgroup of 2 filers holding10,967$240K+287Timeline
LECAP ASSET MANAGEMENT LTD10,759$235K0.05%new13F-HRTimeline
Qsemble Capital Management, LP9,670$211K0.02%+3,34613F-HRTimeline
Kaufman Rossin Wealth, LLC9,577$209K0.15%new13F-HRTimeline
Legacy Capital Group California, Inc.9,554$209K0.07%+2,35913F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…8,362$183K<0.01%013F-HRTimeline
AMALGAMATED BANK7,245$158K<0.01%+29113F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…6,586$144K<0.01%+15013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,500$142K<0.01%-13,46513F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co6,189$136K<0.01%013F-HRTimelineGroup
Stelac Advisory Services LLC5,520$121K0.05%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN4,624$101K<0.01%-99213F-HRTimelineGroup
Covestor Ltd3,995$87K0.06%+313F-HRTimeline
KBC Group NVin group KBC Group NV3,850$84K<0.01%-100,43713F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC3,553$77K<0.01%new13F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.3,185$69.7K<0.01%+57313F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\2,345$51.3K<0.01%-87813F-HRTimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.1,901$41.6K<0.01%-2413F-HRTimelineGroup
Clearstead Advisors, LLC1,811$39.6K<0.01%new13F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC1,252$27.4K<0.01%+1,22113F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,238$27.1K<0.01%+45213F-HRTimelineGroup
Leonteq Securities AG1,221$26.8K<0.01%-78313F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,112$24.3K<0.01%-23313F-HRTimelineGroup
Parallel Advisors, LLC1,069$23.4K<0.01%+33213F-HRTimeline
Headlands Technologies LLC812$17.8K<0.01%new13F-HRTimeline