APLS APELLIS PHARMACEUTICALS INC

COM (common)

10 managers (10 13F filers) reported a position in APLS shares at 2025-12-31, 21,712,932 shares in all. 0 filers opened a position and 0 filers sold out during the quarter.

Managers: 10
13F filers: 10
New: 0
Added: 0
Reduced: 3
Sold out: 0
Shares held by filers: 21,712,932

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

Holder	Shares	Value	% of portfolio	Change	Source
Avoro Capital Advisors LLC	12,222,222	$307M	3.02%		13F-HR/A Timeline
MORGAN STANLEYin group MORGAN STANLEY	9,173,004	$230M	0.01%	-470,244	13F-HR/A Timeline Group
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC	189,205	$4.75M	<0.01%		13F-HR/A Timeline Group
ALGERT GLOBAL LLC	109,733	$2.76M	0.04%	0	13F-HR/A Timeline
AlphaGrep UK Ltd	8,323	$209K	0.07%		13F-HR Timeline
Essential Partners LLC	5,107	$128K	0.04%	-12,652	13F-HR Timeline
Ensign Peak Advisors, Inc	4,747	$119K	<0.01%	-11,800	13F-HR/A Timeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…	503	$12.6K	<0.01%		13F-HR/A Timeline Group
Capital Analysts, LLCin group Capital Analysts, LLC	57	$1K	<0.01%		13F-HR/A Timeline Group
Basecamp Wealth Advisors LLC	31	$779	<0.01%		13F-HR Timeline