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Disclosery

EcoR1 Capital, LLC: APLS position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of EcoR1 Capital, LLC on APLS, newest first. How the timeline and the estimate are built.

EcoR1 Capital, LLC held 0 APLS shares at 2025-12-31 per its 13F-HR filed 2026-02-17.

the latest 13F is the newest step

  1. period ended2025-12-31
    13F 0 shares
    Change vs previous 13F -3,447,156 shares

    13F-HR 0000935836-26-000101 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  2. period ended2025-09-30
    13F 3,447,156 shares
    Change vs previous 13F -8,448,652 shares

    3.74% of the 13F portfolio, value $78,009,140.

    13F-HR 0000935836-25-000671 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-06-30
    13F 11,895,808 shares
    Change vs previous 13F 0 shares

    12.21% of the 13F portfolio, value $205,916,436.

    13F-HR 0000935836-25-000506 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-03-31
    13F 11,895,808 shares
    Change vs previous 13F +4,965 shares

    15.46% of the 13F portfolio, value $260,161,321.

    13F-HR 0000935836-25-000338 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2024-12-31
    13F 11,890,843 shares
    Change vs previous 13F 0 shares

    15.16% of the 13F portfolio, value $379,436,800.

    13F-HR 0000935836-25-000164 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2024-09-30
    13F 11,890,843 shares
    Change vs previous 13F not available

    11.74% of the 13F portfolio, value $342,931,912.

    13F-HR 0000935836-24-000682 filed by EcoR1 Capital, LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).