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Disclosery

AGIO AGIOS PHARMACEUTICALS INC

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COM (common), issuer CIK 1439222

218 managers (221 13F filers) reported a position in AGIO shares at 2025-09-30, 63,500,830 shares in all. 39 filers opened a position and 35 filers sold out during the quarter.

Managers
218
13F filers
221
New
39
Added
69
Reduced
69
Sold out
35
Shares held by filers
63,500,830

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FARALLON CAPITAL MANAGEMENT, L.L.C.5,781,066$232M1.31%+13,60013F-HR/ATimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC5,604,876$225M<0.01%-77,14313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,545,738$182M<0.01%-288,02213F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG3,714,736$149M3.1%+124,58613F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH2,764,900$109M1.05%+438,41113F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …2,673,555$107M3.18%+1,531,04413F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,471,416$99.2M0.02%+2,049,28713F-HRTimelineGroup
Commodore Capital LPin group Commodore Capital LP2,338,287$93.9M4.58%+13,28713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP2,262,712$90.8M<0.01%+311,59913F-HRTimelineGroup
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD1,958,101$78.6M0.09%+57,50513F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/1,656,938$66.5M0.01%-617,31113F-HRTimeline
TCG Crossover Management, LLC1,430,041$57.4M2.82%+733,03813F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,416,315$56.9M<0.01%+10,56013F-HRTimelineGroup
Frazier Life Sciences Management, L.P.1,279,754$51.4M1.54%013F-HRTimeline
Caligan Partners LP1,131,205$45.4M6.3%+59,94713F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,130,000$45.4M<0.01%+9,69213F-HR/ATimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,021,201$41M0.01%-84,89213F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …987,339$39.6M0.1%-29,55213F-HRTimelineGroup
Rock Springs Capital Management LP958,542$38.5M2.25%-31,20313F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\926,734$37.2M0.01%+5,14813F-HRTimelineGroup
Fisher Asset Management, LLC870,145$34.9M0.01%-7,39513F-HRTimeline
GW&K Investment Management, LLC852,942$34.2M0.3%-15,67613F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC804,766$32.3M<0.01%+156,70513F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…800,000$32.1M0.05%+9,00013F-HRTimelineGroup
ARMISTICE CAPITAL, LLC764,000$30.7M0.96%-404,00013F-HRTimeline
ArrowMark Colorado Holdings LLC679,922$27.3M0.51%+21,23113F-HRTimeline
SCS Capital Management LLC598,765$24M0.26%-5,32013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP555,410$22.3M<0.01%-1,39513F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…530,098$21.3M0.07%+24,87313F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management495,491$19.9M0.04%new13F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC495,341$19.9M0.5%+48,32213F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC491,982$19.7M0.02%-589,48813F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co482,186$19.4M<0.01%+6,14513F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY416,998$16.7M<0.01%+125,03313F-HR/ATimelineGroup
Artisan Partners Limited Partnership402,943$16.2M0.02%+12,95913F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC395,120$15.9M0.02%+361,63113F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.367,749$14.8M0.01%-228,45313F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding349,688$14M+13,452Timeline
Legal & General Group Plcin group Legal & General Group Plc322,934$13M<0.01%+258,62913F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp270,096$10.8M<0.01%+3,44213F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…272,161$10.7M0.01%-22,57913F-HRTimelineGroup
Palo Alto Investors LP265,497$10.7M1.97%-3,28613F-HRTimeline
SummitTX Capital, L.P.262,977$10.6M0.44%new13F-HRTimeline
Eagle Health Investments LP246,230$9.88M2.59%-84,60013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP226,824$9.1M0.01%-457,84513F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC216,040$8.67M<0.01%+35,33613F-HR/ATimelineGroup
HighVista Strategies LLC195,298$7.84M1.92%+125,17113F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP189,866$7.62M0.06%013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO183,100$7.35M<0.01%-844,31713F-HR/ATimelineGroup
AXA Investment Managers S.A.177,675$7.13M0.02%13F-HRTimeline
PEREGRINE CAPITAL MANAGEMENT LLC162,905$6.54M0.2%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE146,643$5.89M0.01%+7,74513F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.146,514$5.88M0.02%new13F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC145,121$5.83M<0.01%+17,47413F-HRTimelineGroup
Patient Square Capital LP133,827$5.37M1.44%-5,90513F-HRTimeline
TD Asset Management Inc128,294$5.15M<0.01%-39,90013F-HRTimeline
Vestal Point Capital, LP127,000$5.1M0.23%new13F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC126,979$5.1M1.03%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.126,976$5.1M<0.01%+14,35913F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…122,500$4.92M0.03%-7,50013F-HR/ATimelineGroup
Nuveen, LLCin group TIAA119,580$4.8M<0.01%013F-HRTimelineGroup
Swiss National Bank106,660$4.28M<0.01%-2,80013F-HRTimeline
Parkman Healthcare Partners LLC100,380$4.03M0.44%new13F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…100,000$4.01M0.25%new13F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC98,239$3.94M<0.01%-60,12013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …96,012$3.85M<0.01%-36,07113F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC91,635$3.61M<0.01%-5,26113F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC87,900$3.53M0.04%new13F-HR/ATimelineGroup
RHUMBLINE ADVISERS87,702$3.52M<0.01%-2,17913F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP74,429$2.99M<0.01%+38,00213F-HRTimelineGroup
Woodline Partners LP73,996$2.97M0.01%-159,07213F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding73,229$2.94MnewTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …71,213$2.86M<0.01%+15,92913F-HRTimelineGroup
Rafferty Asset Management, LLC68,220$2.74M0.01%+18,81713F-HRTimeline
Assenagon Asset Management S.A.67,153$2.7M<0.01%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.61,503$2.47M<0.01%+3313F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…61,296$2.46M<0.01%+13,63713F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP55,000$2.21M0.04%-25,00013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND49,790$2M<0.01%+10,69713F-HRTimeline
Phocas Financial Corp.46,608$1.87M0.24%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN44,754$1.8M<0.01%+7,06013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC43,620$1.75M<0.01%-12,86913F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al41,061$1.65M0.01%-8,60013F-HRTimeline
DekaBank Deutsche Girozentrale40,000$1.56M<0.01%013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding38,838$1.56M-2,978Timeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC38,428$1.54M<0.01%-13,82413F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC37,000$1.49M0.15%+1,10013F-HRTimelineGroup
ALGERT GLOBAL LLC35,770$1.44M0.02%-53,06013F-HR/ATimeline
STATE OF WISCONSIN INVESTMENT BOARD35,573$1.43M<0.01%-23,52713F-HRTimeline
EDGEWOOD MANAGEMENT LLC35,000$1.4M<0.01%013F-HRTimeline
HARBOR CAPITAL ADVISORS, INC.34,835$1.4M0.11%-2,18913F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…34,032$1.37M0.01%013F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO32,300$1.3M<0.01%+21,97413F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC30,232$1.21M<0.01%+81813F-HRTimeline
SG Americas Securities, LLC27,650$1.11M<0.01%new13F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC27,554$1.11M0.01%-3,72013F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.25,501$1.02M0.04%+10,49613F-HRTimeline
OAK RIDGE INVESTMENTS LLC25,385$1.02M0.07%-11,86713F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC24,641$989K0.02%-12,06413F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson23,797$955K<0.01%013F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC23,578$946K0.01%+78513F-HRTimeline
FMR LLCin group FMR LLC20,712$831K<0.01%+2,12013F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…20,476$822K<0.01%+4,08013F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co20,325$796K<0.01%+66213F-HRTimelineGroup
Handelsbanken Fonder AB19,323$776K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA17,527$705K<0.01%-5,63713F-HRTimelineGroup
Caption Management, LLC17,494$702K0.04%+49413F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd16,400$658K0.02%new13F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM16,255$652K<0.01%-42113F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…16,038$644K<0.01%new13F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC15,902$638K<0.01%-2,00213F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…15,847$636K<0.01%013F-HRTimeline
Police & Firemen's Retirement System of…15,633$628K0.01%+2,71013F-HRTimeline
Freestone Grove Partners LP15,424$619K<0.01%new13F-HRTimeline
PROFUND ADVISORS LLC15,109$606K0.02%+4,25813F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC14,914$599K<0.01%-64613F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS14,698$590K<0.01%+2,79013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS13,484$541K<0.01%-1,92113F-HRTimeline
Atria Investments, Inc13,386$537K0.01%-8713F-HRTimeline
Henshaw Capital LLC13,227$531K0.02%-81413F-HRTimeline
Creative Planningin group Creative Planning13,119$527K<0.01%+28013F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…12,881$517K0.15%013F-HRTimelineGroup
Ensign Peak Advisors, Inc12,620$507K<0.01%-12,35013F-HR/ATimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…12,071$485K0.01%-17,10613F-HRTimelineGroup
Savvy Advisors, Inc.11,993$481K0.02%-9,78813F-HRTimeline
KLP KAPITALFORVALTNING AS11,800$474K<0.01%013F-HRTimeline
ProShare Advisors LLC11,728$471K<0.01%-2,01613F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC11,395$457K0.04%-33313F-HRTimelineGroup
Gallagher Fiduciary Advisors, LLCin group Gallagher Fiduciary Advisors,…11,260$452K0.02%-21313F-HRTimelineGroup
OMERS ADMINISTRATION Corp11,200$450K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…10,184$409K0.03%-1,44813F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC10,134$407K<0.01%-5,27413F-HRTimelineGroup
Cinctive Capital Management LP10,099$405K0.02%new13F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC9,423$378K<0.01%-67713F-HRTimelineGroup
COMMERCE BANKin group COMMERCE BANK9,159$368K<0.01%-44513F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd7,932$318K0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…6,856$275K<0.01%-2,43613F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…6,796$273K<0.01%013F-HRTimeline
Voleon Capital Management LP6,682$268K0.01%new13F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.6,507$261K<0.01%new13F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC6,439$258K<0.01%-35013F-HRTimelineGroup
Cubist Systematic Strategies, LLC6,264$251K<0.01%new13F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.6,021$242K<0.01%13F-HR/ATimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co5,454$219K<0.01%new13F-HRTimelineGroup
AlphaQuest LLC5,411$217K0.01%+4,74213F-HRTimeline
NORTHCAPE WEALTH MANAGEMENT, LLC5,240$210K0.06%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC5,049$203K<0.01%-295,15413F-HRTimelineGroup
NORTH STAR ASSET MANAGEMENT INC5,000$201K0.01%new13F-HRTimeline
Quarry LP5,000$201K0.05%new13F-HRTimeline
CWM, LLCin group CWM, LLC4,791$192K<0.01%-49513F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…4,719$189K0.01%-1,19413F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…4,554$183K<0.01%+13513F-HRTimelineGroup
Sterling Capital Management LLC3,911$157K<0.01%+2,39613F-HRTimeline
TORNO CAPITAL, LLC2,500$100K0.01%new13F-HR/ATimeline
Quantbot Technologies LP1,976$79.3K<0.01%new13F-HRTimeline
AMALGAMATED BANK1,957$79K<0.01%013F-HRTimeline
KBC Group NVin group KBC Group NV1,751$70K<0.01%013F-HRTimelineGroup
BIT Capital GmbH1,571$63.1K<0.01%-65913F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,357$54.5K<0.01%-5,08313F-HRTimelineGroup
NewEdge Advisors, LLC1,273$51.1K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,250$50.2K<0.01%-21013F-HRTimeline
FIRST HORIZON CORP1,124$45.1K<0.01%13F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC955$38.3K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC780$31.3K<0.01%013F-HRTimeline
Arax Advisory Partners702$28.2K<0.01%+68913F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\569$22.8K<0.01%013F-HRTimelineGroup
SIGNATUREFD, LLC513$20.6K<0.01%013F-HRTimeline
Smartleaf Asset Management LLC398$15.6K<0.01%+23113F-HRTimeline
COMERICA BANK374$15K<0.01%+2113F-HRTimeline
Hurley Capital, LLC366$14.7K0.01%013F-HRTimeline
Aspect Partners, LLC361$14.5K0.01%013F-HRTimeline
Advisory Services Network, LLC350$14K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.336$13.5K<0.01%-1113F-HRTimelineGroup
Versant Capital Management, Inc316$12.7K<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.310$12.4K<0.01%+513F-HRTimelineGroup
Bell Investment Advisors, Inc298$12K<0.01%013F-HRTimeline
Clearstead Advisors, LLC291$11.7K<0.01%013F-HRTimeline
LANARK FINANCIAL, INC.241$9.67K<0.01%-10413F-HRTimeline
Spire Wealth Managementin group Spire Wealth Management230$9.23K<0.01%013F-HRTimelineGroup
GAMMA Investing LLC206$8.27K<0.01%+2313F-HRTimeline
Hillsdale Investment Management Inc.200$8.03K<0.01%013F-HRTimeline
Concord Wealth Partnersin group Concord Wealth Partners200$8.03K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.204$8K<0.01%013F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC186$7K<0.01%+7613F-HRTimelineGroup
Farther Finance Advisors, LLC161$6.46K<0.01%+1013F-HRTimeline
Essential Partners LLC115$4.62K<0.01%013F-HRTimeline
Root Financial Partners, LLC106$4.25K<0.01%new13F-HRTimeline
MATHER GROUP, LLC.95$3.81K<0.01%new13F-HRTimeline
Private Wealth Management Group, LLC84$3.37K<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC75$3.01K<0.01%-1513F-HRTimeline
Covestor Ltd64$3K<0.01%+6113F-HRTimeline
Larson Financial Group LLC74$2.97K<0.01%new13F-HRTimeline
JPL Wealth Management, LLC70$2.81K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…62$2.49K<0.01%013F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.53$2.13K<0.01%-54413F-HRTimelineGroup
HALBERT HARGROVE GLOBAL ADVISORS, LLC47$1.89K<0.01%new13F-HRTimeline
Parkside Financial Bank & Trust45$1.81K<0.01%013F-HRTimeline
RAFFA WEALTH MANAGEMENT, LLC32$1.28K<0.01%013F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…30$1.2K<0.01%new13F-HRTimelineGroup
MAI Capital Management25$1K<0.01%-913F-HRTimeline