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TWO SIGMA INVESTMENTS, LP: AGIO position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on AGIO, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 536,380 AGIO shares at 2026-06-30 per its 13F-HR filed 2026-08-14.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 536,380 shares
    Change vs previous 13F +284,744 shares

    0.01% of the 13F portfolio, value $19,905,062.

    13F-HR 0000899140-26-000855 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 251,636 shares
    Share basis changed not comparable

    Membership change: TWO SIGMA ADVISERS, LP left the group. 0.01% of the 13F portfolio, value $8,512,846.

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 385,356 shares
    Change vs previous 13F +312,127 shares

    0.01% of the 13F portfolio, value $10,489,390.

    13F-HR 0000899140-26-000232 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 300,156 shares
    • TWO SIGMA ADVISERS, LP: 85,200 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 73,229 shares
    Change vs previous 13F +73,229 shares

    <0.01% of the 13F portfolio, value $2,939,412.

    13F-HR 0000899140-25-001286 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 59,629 shares
    • TWO SIGMA ADVISERS, LP: 13,600 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-03-31
    13F 0 shares
    Change vs previous 13F -131,573 shares

    13F-HR 0000899140-25-000680 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 0 shares
    • TWO SIGMA ADVISERS, LP: 0 shares

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  6. period ended2024-12-31
    13F 131,573 shares
    Change vs previous 13F not available

    <0.01% of the 13F portfolio, value $4,323,489.

    13F-HR 0000899140-25-000265 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 109,373 shares
    • TWO SIGMA ADVISERS, LP: 22,200 shares

    Acceptance time not in the bulk data set (spec §4.2).