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Kynam Capital Management, LP

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13F filer, CIK 1907884, PRINCETON, NJ

Kynam Capital Management, LP reported $1,565,452,855 across 37 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 73.25% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001907884-26-000001

Period
2025-12-31
Reported value
$1.57B
Holdings
37
Top 10 weight
73.25%
New
7
Sold out
5

Largest buys vs the previous quarter

SecurityShares changeApprox. value
CTMXadded+5,319,574$22.7M
KALVadded+1,204,783$19.5M
CGEMadded+811,960$8.4M
BHVNnew+702,884$7.94M
STROnew+479,590$5.55M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
VRDNreduced-2,957,386-$92M
COGTreduced-1,720,949-$61.1M
CGONreduced-1,059,375-$44M
WVEreduced-2,390,948-$40.6M
MBXreduced-1,065,201-$33.6M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001907884-26-000001, largest first. % of portfolio is the value over $1,536,043,215, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,239,731 shares; 2024Q4: 9,105,000 shares; 2025Q1: 9,105,000 shares; 2025Q2: 8,492,557 shares; 2025Q3: 7,886,172 shares; 2025Q4: 6,165,223 shares 6,165,223$219M14.26%-1,720,949Timeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,576,549 shares; 2024Q4: 1,457,910 shares; 2025Q1: 2,400,000 shares; 2025Q2: 3,426,887 shares; 2025Q3: 4,027,800 shares; 2025Q4: 3,433,051 shares 3,433,051$174M11.32%-594,749Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,842,925 shares; 2024Q4: 8,520,000 shares; 2025Q1: 8,520,000 shares; 2025Q2: 8,520,000 shares; 2025Q3: 8,520,000 shares; 2025Q4: 8,050,959 shares 8,050,959$169M11.01%-469,041Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,458,609 shares; 2024Q4: 5,064,207 shares; 2025Q1: 6,500,000 shares; 2025Q2: 6,100,729 shares; 2025Q3: 6,100,729 shares; 2025Q4: 5,943,180 shares 5,943,180$161M10.51%-157,549Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,039,288 shares; 2024Q4: 2,336,796 shares; 2025Q1: 3,200,000 shares; 2025Q2: 3,071,588 shares; 2025Q3: 3,071,588 shares; 2025Q4: 2,922,335 shares 2,922,335$135M8.78%-149,253Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,085,368 shares; 2024Q4: 9,085,368 shares; 2025Q1: 8,928,523 shares; 2025Q2: 8,463,742 shares; 2025Q3: 9,390,270 shares; 2025Q4: 9,366,526 shares 9,366,526$73.1M4.76%-23,744Timeline
BEAMBEAM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,302,085 shares; 2024Q4: 1,756,158 shares; 2025Q1: 2,518,170 shares; 2025Q2: 2,417,647 shares; 2025Q3: 2,517,647 shares; 2025Q4: 2,440,214 shares 2,440,214$67.6M4.4%-77,433Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,511,295 shares; 2024Q4: 3,326,262 shares; 2025Q1: 4,700,000 shares; 2025Q2: 4,427,927 shares; 2025Q3: 4,427,927 shares; 2025Q4: 1,470,541 shares 1,470,541$45.8M2.98%-2,957,386Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 467,947 shares; 2024Q4: 530,478 shares; 2025Q1: 2,406,067 shares; 2025Q2: 2,329,998 shares; 2025Q3: 2,329,998 shares; 2025Q4: 1,564,492 shares 1,564,492$41.1M2.68%-765,506Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,770,805 shares; 2024Q4: 2,519,705 shares; 2025Q1: 2,611,662 shares; 2025Q2: 2,457,667 shares; 2025Q3: 2,005,205 shares; 2025Q4: 945,830 shares 945,830$39.3M2.56%-1,059,375Timeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 2,154,413 shares; 2025Q3: 3,646,503 shares; 2025Q4: 8,966,077 shares 8,966,077$38.2M2.49%+5,319,574Timeline
NRIXNURIX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 800,000 shares; 2025Q2: 1,173,605 shares; 2025Q3: 2,168,605 shares; 2025Q4: 1,970,357 shares 1,970,357$37.4M2.43%-198,248Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,899,497 shares; 2024Q4: 4,899,497 shares; 2025Q1: 4,899,497 shares; 2025Q2: 4,560,053 shares; 2025Q3: 4,560,053 shares; 2025Q4: 2,169,105 shares 2,169,105$36.9M2.4%-2,390,948Timeline
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,252,738 shares; 2025Q1: 2,338,629 shares; 2025Q2: 2,095,998 shares; 2025Q3: 2,302,172 shares; 2025Q4: 3,114,132 shares 3,114,132$32.2M2.1%+811,960Timeline
IMCRIMMUNOCORE HLDGS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,225,576 shares; 2025Q1: 1,695,576 shares; 2025Q2: 976,267 shares; 2025Q3: 1,009,267 shares; 2025Q4: 856,462 shares 856,462$29.7M1.94%-152,805Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,000,000 shares; 2025Q4: 934,799 shares 934,799$29.5M1.92%-1,065,201Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 606,171 shares; 2025Q4: 1,810,954 shares 1,810,954$29.2M1.9%+1,204,783Timeline
APLSAPELLIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 808,607 shares; 2025Q4: 908,607 shares 908,607$22.8M1.49%+100,000Timeline
DVAXDYNAVAX TECHNOLOGIES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,332,687 shares; 2024Q4: 6,560,835 shares; 2025Q1: 2,620,797 shares; 2025Q2: 2,145,319 shares; 2025Q3: 2,145,319 shares; 2025Q4: 1,375,632 shares 1,375,632$21.2M1.38%-769,687Timeline
BNRBURNING ROCK BIOTECH LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 989,217 shares; 2024Q4: 994,883 shares; 2025Q1: 994,883 shares; 2025Q2: 994,883 shares; 2025Q3: 994,883 shares; 2025Q4: 994,883 shares 994,883$20M1.31%0Timeline
TVTXTRAVERE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,371,511 shares; 2024Q4: 1,802,750 shares; 2025Q1: 1,802,750 shares; 2025Q2: 1,540,691 shares; 2025Q3: 949,727 shares; 2025Q4: 517,884 shares 517,884$19.8M1.29%-431,843Timeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 675,000 shares; 2025Q4: 640,395 shares 640,395$17.8M1.16%-34,605Timeline
ENGNENGENE HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,736,227 shares; 2024Q4: 4,994,090 shares; 2025Q1: 4,994,090 shares; 2025Q2: 4,994,090 shares; 2025Q3: 4,994,090 shares; 2025Q4: 1,492,898 shares 1,492,898$13.5M0.88%-3,501,192Timeline
RLAYRELAY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,000,000 shares; 2025Q1: 3,063,292 shares; 2025Q2: 2,887,014 shares; 2025Q3: 2,887,014 shares; 2025Q4: 1,424,259 shares 1,424,259$12M0.78%-1,462,755Timeline
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 702,884 shares 702,884$7.94M0.52%newTimeline
DSGNDESIGN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 904,017 shares; 2025Q2: 1,029,579 shares; 2025Q3: 1,029,579 shares; 2025Q4: 784,606 shares 784,606$7.36M0.48%-244,973Timeline
STROSUTRO BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 479,590 shares 479,590$5.55M0.36%newTimeline
AMRNAMARIN CORP PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 576,111 shares; 2025Q3: 576,111 shares; 2025Q4: 389,273 shares 389,273$5.43M0.35%-186,838Timeline
GERNGERON CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,659,526 shares; 2025Q2: 3,456,318 shares; 2025Q3: 3,456,318 shares; 2025Q4: 3,456,318 shares 3,456,318$4.56M0.3%0Timeline
CLYMCLIMB BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 547,000 shares; 2025Q1: 1,047,000 shares; 2025Q2: 1,028,341 shares; 2025Q3: 1,028,341 shares; 2025Q4: 1,028,341 shares 1,028,341$4.11M0.27%0Timeline
CRBUCARIBOU BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,356,147 shares; 2024Q4: 2,406,147 shares; 2025Q1: 3,269,147 shares; 2025Q2: 3,067,774 shares; 2025Q3: 3,067,774 shares; 2025Q4: 2,503,302 shares 2,503,302$3.98M0.26%-564,472Timeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 185,482 shares 185,482$3.18M0.21%newTimeline
PRQRPROQR THRAPEUTICS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,750,000 shares; 2025Q1: 1,750,000 shares; 2025Q2: 1,649,462 shares; 2025Q3: 1,649,462 shares; 2025Q4: 1,566,317 shares 1,566,317$3.16M0.21%-83,145Timeline
ALECALECTOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,000,000 shares 2,000,000$3.12M0.2%newTimeline
PRLDPRELUDE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 788,867 shares 788,867$2.29M0.15%newTimeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
BEAMBEAM THERAPEUTICS INC COMcall937,000$26Mnew
OMEROMEROS CORP COMput200,000$3.44Mnew

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
UTHRUNITED THERAPEUTICS CORP DEL67,588$20Mshares
IRWDIRONWOOD PHARMACEUTICALS INC5,466,825$7.16Mshares
URGNUROGEN PHARMA LTD282,412$6.94Mshares
SUTRO BIOPHARMA INCSUTRO BIOPHARMA INC5,088,099$4.42Mshares
EWTXEDGEWISE THERAPEUTICS INC253,979$4.12Mshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001907884-26-000001 base2026-02-17acceptance time not in the bulk data set