WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 6,657,735 $174M 0.03% -1,778,871 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 6,567,892 $172M 0.09% -2,192,182 13F-HR Timeline Group Capital World Investors More: the full row for Capital World Investors 6,433,424 $168M 0.03% -1,959 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 5,475,505 $143M 0.01% +4,830,646 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 3,166,946 $82.9M 0.01% +1,452,589 13F-HR/A Timeline Group RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 2,509,119 $65.7M 0.99% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 2,354,025 $61.7M 0.01% +548,378 13F-HR Timeline BAMCO INC /NY/ in group Baron Capital More: the full row for BAMCO INC /NY/ 1,909,088 $50M 0.13% +2,568 13F-HR Timeline Group Clearbridge Investments, LLC in group Franklin Resources More: the full row for Clearbridge Investments, LLC 1,862,842 $48.8M 0.04% +989,664 13F-HR Timeline Group PRINCIPAL FINANCIAL GROUP INC group of 2 filers holding More: the full row for PRINCIPAL FINANCIAL GROUP INC 1,763,244 $46.2M +1,763,239 Timeline Woodline Partners LP More: the full row for Woodline Partners LP 1,759,797 $46.1M 0.31% +151,835 13F-HR Timeline Allianz Asset Management GmbH in group Allianz SE More: the full row for Allianz Asset Management GmbH 1,505,866 $39.4M 0.06% +984,041 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 1,305,337 $34.2M 1.3% -10,336 13F-HR Timeline RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 1,295,040 $33.9M 0.45% new 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 1,045,837 $27.4M 5.65% +513,383 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 935,916 $24.5M +861,744 Timeline Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 841,735 $22M 0.1% +237,582 13F-HR Timeline MPM BIOIMPACT LLC More: the full row for MPM BIOIMPACT LLC 800,000 $21M 2.97% new 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 579,528 $15.2M <0.01% -69,186 13F-HR Timeline Group C WorldWide Group Holding A/S in group C WorldWide Group Holding A/S More: the full row for C WorldWide Group Holding A/S 500,000 $13.1M 0.16% 0 13F-HR Timeline Group SUPERSTRING CAPITAL MANAGEMENT LP More: the full row for SUPERSTRING CAPITAL MANAGEMENT LP 403,630 $10.6M 9.28% -223,302 13F-HR Timeline B Group, Inc. More: the full row for B Group, Inc. 400,000 $10.5M 6.4% 13F-HR Timeline Candriam S.C.A. More: the full row for Candriam S.C.A. 375,479 $9.83M 0.06% -14,544 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 309,128 $8.1M 0.01% +84,400 13F-HR Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 300,000 $7.86M 0.47% new 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 288,992 $7.57M 0.01% new 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 283,600 $7.43M 0.02% +270,136 13F-HR Timeline Group Capital International Investors in group Capital International Investo… More: the full row for Capital International Investors 264,986 $6.94M <0.01% +120,000 13F-HR Timeline Group Nan Fung Group Holdings Ltd More: the full row for Nan Fung Group Holdings Ltd 235,000 $6.15M 5.26% 0 13F-HR Timeline Alberta Investment Management Corp More: the full row for Alberta Investment Management Corp 232,293 $6.08M 0.04% +69,740 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 231,694 $6.07M 0.01% -25,938 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 230,928 $6.05M <0.01% -20,579 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 187,800 $4.92M 0.01% +99,500 13F-HR Timeline Privium Fund Management B.V. More: the full row for Privium Fund Management B.V. 185,062 $4.85M 1.1% -30,562 13F-HR Timeline Hennion & Walsh Asset Management, Inc. More: the full row for Hennion & Walsh Asset Management, Inc. 183,317 $4.8M 0.22% +41,128 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 180,052 $4.72M <0.01% -1,156,320 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 161,635 $4.23M <0.01% +23,510 13F-HR Timeline Group MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 160,378 $4.2M <0.01% +39,294 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 140,809 $3.69M <0.01% -12,646 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 126,202 $3.31M 0.02% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 123,387 $3.23M <0.01% -15,023 13F-HR Timeline Group FIL Ltd in group FIL Ltd More: the full row for FIL Ltd 111,713 $2.93M <0.01% -14,228 13F-HR Timeline Group Eversept Partners, LP More: the full row for Eversept Partners, LP 102,930 $2.7M 0.28% -32,289 13F-HR Timeline SCHRODER INVESTMENT MANAGEMENT GROUP More: the full row for SCHRODER INVESTMENT MANAGEMENT GROUP 91,504 $2.42M <0.01% -147,363 13F-HR Timeline ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 88,395 $2.32M 0.01% +13,730 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 82,727 $2.16M <0.01% -19,623 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 73,412 $1.92M <0.01% +64,563 13F-HR Timeline Group Cubist Systematic Strategies, LLC More: the full row for Cubist Systematic Strategies, LLC 72,619 $1.9M 0.03% -23,731 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 70,954 $1.86M <0.01% +1,207 13F-HR Timeline Group AXA S.A. in group AXA S.A. More: the full row for AXA S.A. 65,814 $1.72M 0.01% 0 13F-HR Timeline Group DCF Advisers, LLC More: the full row for DCF Advisers, LLC 64,750 $1.7M 0.86% +22,500 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 63,909 $1.67M <0.01% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 62,114 $1.63M <0.01% -39,564 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 55,520 $1.45M <0.01% +11,894 13F-HR Timeline Group Robeco Institutional Asset Management B… in group Robeco Institutional Asset Ma… More: the full row for Robeco Institutional Asset Management B.V. 52,035 $1.36M <0.01% 0 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 49,365 $1.29M <0.01% +26,700 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP group of 2 filers holding More: the full row for TWO SIGMA INVESTMENTS, LP 47,957 $1.26M -34,055 Timeline SECTORAL ASSET MANAGEMENT INC More: the full row for SECTORAL ASSET MANAGEMENT INC 44,800 $1.17M 0.78% -28,070 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 44,340 $1.16M <0.01% +1,790 13F-HR Timeline Group LAZARD ASSET MANAGEMENT LLC in group LAZARD ASSET MANAGEMENT LLC More: the full row for LAZARD ASSET MANAGEMENT LLC 43,178 $1.13M <0.01% new 13F-HR Timeline Group Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 42,163 $1.1M 0.02% +29,253 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 40,954 $1.07M <0.01% +40,454 13F-HR Timeline Group RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 39,420 $1.03M <0.01% 13F-HR/A Timeline Group WealthPlan Investment Management, LLC More: the full row for WealthPlan Investment Management, LLC 39,393 $1.03M 0.1% 0 13F-HR Timeline ENVESTNET ASSET MANAGEMENT INC in group ENVESTNET ASSET MANAGEMENT INC More: the full row for ENVESTNET ASSET MANAGEMENT INC 37,278 $976K <0.01% new 13F-HR Timeline Group DekaBank Deutsche Girozentrale More: the full row for DekaBank Deutsche Girozentrale 36,648 $966K <0.01% 0 13F-HR Timeline BAROMETER CAPITAL MANAGEMENT INC. More: the full row for BAROMETER CAPITAL MANAGEMENT INC. 39,100 $913K 0.37% +26,600 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 27,961 $732K <0.01% new 13F-HR Timeline Group TWINBEECH CAPITAL LP More: the full row for TWINBEECH CAPITAL LP 27,039 $708K 0.01% new 13F-HR Timeline M&T Bank Corp in group M&T Bank Corp More: the full row for M&T Bank Corp 25,123 $658K <0.01% -65 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 23,508 $616K <0.01% -233,103 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 23,208 $608K <0.01% new 13F-HR Timeline Group DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. in group DYMON ASIA CAPITAL (SINGAPORE… More: the full row for DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. 20,000 $524K 0.37% new 13F-HR Timeline Group LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 19,840 $520K 0.01% new 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 19,755 $517K <0.01% +18,472 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 19,502 $511K <0.01% new 13F-HR Timeline HSBC HOLDINGS PLC in group HSBC HOLDINGS PLC More: the full row for HSBC HOLDINGS PLC 18,840 $493K <0.01% new 13F-HR Timeline Group PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O… More: the full row for PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 18,480 $484K <0.01% +3,179 13F-HR Timeline BANK OF MONTREAL /CAN/ in group BANK OF MONTREAL /CAN/ More: the full row for BANK OF MONTREAL /CAN/ 16,893 $442K <0.01% +2,993 13F-HR Timeline Group DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 15,555 $407K <0.01% 0 13F-HR Timeline Group Bayesian Capital Management, LP More: the full row for Bayesian Capital Management, LP 15,469 $405K 0.05% new 13F-HR Timeline Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 15,100 $402K <0.01% 0 13F-HR Timeline Group FOX RUN MANAGEMENT, L.L.C. More: the full row for FOX RUN MANAGEMENT, L.L.C. 13,946 $365K 0.07% new 13F-HR Timeline Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 13,833 $362K <0.01% +4,276 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 13,487 $353K 0.03% -18,131 13F-HR Timeline Group VIRTUS ADVISERS, LLC in group Virtus Investment Advisers, L… More: the full row for VIRTUS ADVISERS, LLC 13,086 $343K 0.14% -3,641 13F-HR Timeline Group Bellevue Group AG in group Bellevue Group AG More: the full row for Bellevue Group AG 13,000 $340K 0.01% new 13F-HR Timeline Group Orion Porfolio Solutions, LLC More: the full row for Orion Porfolio Solutions, LLC 11,956 $313K <0.01% new 13F-HR Timeline Orion Portfolio Solutions, LLC More: the full row for Orion Portfolio Solutions, LLC 11,956 $313K <0.01% new 13F-HR Timeline Bridgefront Capital, LLC More: the full row for Bridgefront Capital, LLC 11,303 $296K 0.1% new 13F-HR Timeline Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 11,300 $296K <0.01% -17,158 13F-HR/A Timeline Group NJ State Employees Deferred Compensatio… More: the full row for NJ State Employees Deferred Compensation Plan 11,300 $296K 0.04% 0 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 11,061 $290K 0.03% +1,502 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 10,881 $285K <0.01% -25,594 13F-HR Timeline Group National Philanthropic Trust More: the full row for National Philanthropic Trust 10,000 $262K <0.01% 0 13F-HR Timeline TOWNSQUARE CAPITAL LLC More: the full row for TOWNSQUARE CAPITAL LLC 9,290 $243K <0.01% new 13F-HR Timeline Kingsview Wealth Management, LLC More: the full row for Kingsview Wealth Management, LLC 8,794 $230K <0.01% -555 13F-HR Timeline Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 8,760 $229K <0.01% -871 13F-HR Timeline Jasper Ridge Partners, L.P. More: the full row for Jasper Ridge Partners, L.P. 8,024 $210K 0.01% new 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 5,865 $154K <0.01% +5,534 13F-HR Timeline Group GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 5,030 $132K <0.01% +946 13F-HR/A Timeline Mirae Asset Global Investments Co., Ltd. in group Mirae Asset Global Investment… More: the full row for Mirae Asset Global Investments Co., Ltd. 4,603 $122K <0.01% +86 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 4,381 $115K <0.01% +2,830 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 3,702 $97K <0.01% +2,856 13F-HR/A Timeline Group STOREBRAND ASSET MANAGEMENT AS More: the full row for STOREBRAND ASSET MANAGEMENT AS 2,580 $67.6K <0.01% 0 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 2,240 $58.7K <0.01% +25 13F-HR/A Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 1,321 $34.6K <0.01% +2 13F-HR Timeline Group Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 1,200 $31.4K <0.01% new 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,095 $28.7K <0.01% 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 438 $11.5K <0.01% -3,010 13F-HR Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 413 $11K <0.01% -33 13F-HR Timeline Group Blue Trust, Inc. More: the full row for Blue Trust, Inc. 382 $10K <0.01% +141 13F-HR/A Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 366 $9.59K <0.01% -1,382 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 332 $8.7K <0.01% -643 13F-HR/A Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 339 $8K <0.01% -11,858 13F-HR Timeline Quent Capital, LLC More: the full row for Quent Capital, LLC 230 $6.02K <0.01% 0 13F-HR Timeline Headlands Technologies LLC More: the full row for Headlands Technologies LLC 210 $5.5K <0.01% new 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 181 $4.74K <0.01% +47 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 141 $3.69K <0.01% new 13F-HR/A Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 98 $2.57K <0.01% +3 13F-HR Timeline Group WHITTIER TRUST CO OF NEVADA INC More: the full row for WHITTIER TRUST CO OF NEVADA INC 80 $2.09K <0.01% new 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 52 $1.36K <0.01% +11 13F-HR Timeline CONQUIS FINANCIAL LLC More: the full row for CONQUIS FINANCIAL LLC 47 $1.23K <0.01% 13F-HR Timeline Retirement Wealth Solutions LLC More: the full row for Retirement Wealth Solutions LLC 38 $962 <0.01% 13F-HR Timeline QUADRANT CAPITAL GROUP LLC More: the full row for QUADRANT CAPITAL GROUP LLC 31 $812 <0.01% 0 13F-HR Timeline PRIVATE TRUST CO NA More: the full row for PRIVATE TRUST CO NA 13 $340 <0.01% new 13F-HR Timeline Global Retirement Partners, LLC More: the full row for Global Retirement Partners, LLC 9 $236 <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 6 $157 <0.01% 13F-HR Timeline CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0% 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios. Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 0 $0 0% new 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.