13F-HR filed by Rock Springs Capital Management LP
Rock Springs Capital Management LP filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 107 holding rows worth $2,626,669,578.
- Accession
- 0001172661-25-000867
- Filer
- CIK 1595725
- Filed
- 2025-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2024
A holdings report, 107 entries on the cover page, a total value of $2,626,669,578 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,626,669,578 with VALUE read as dollars as filed, 13F file number 028-16048. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 229,600 | $141,204,000 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 216,000 | $112,743,360 | dollars as filed | |
| Eli Lilly and Company | 532457108 | COM | 144,500 | $111,554,000 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 720,500 | $98,348,250 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 1,096,899 | $95,671,531 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 176,000 | $89,031,360 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 4,973,649 | $86,640,966 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 265,212 | $81,836,467 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 1,739,813 | $73,193,933 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 1,162,718 | $65,088,954 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 1,471,564 | $60,849,171 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 256,200 | $60,286,422 | dollars as filed | |
| PENUMBRA INC COM | 70975L107 | Stock | 240,000 | $56,995,200 | dollars as filed | |
| WEST PHARMACEUTICAL SVSC INC COM | 955306105 | Stock | 168,750 | $55,275,750 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 1,213,257 | $53,067,861 | dollars as filed | |
| PHREESIA INC | 71944F106 | COM | 2,040,000 | $51,326,400 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 1,251,859 | $49,072,873 | dollars as filed | |
| FRESHPET INC COM | 358039105 | Stock | 327,500 | $48,506,025 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 305,000 | $41,989,350 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 1,034,137 | $41,603,332 | dollars as filed | |
| Boston Scientific Corporation | 101137107 | COM | 460,000 | $41,087,200 | dollars as filed | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 545,000 | $40,346,350 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 550,000 | $37,972,000 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 892,549 | $37,531,685 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 307,500 | $37,388,925 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 397,500 | $35,842,575 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 1,305,337 | $34,186,776 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 429,994 | $33,659,930 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 9,599,170 | $33,597,095 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 716,782 | $30,979,318 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 1,222,182 | $30,884,539 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 114,250 | $29,827,248 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 1,080,963 | $29,315,717 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 353,000 | $27,452,810 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 946,499 | $26,331,602 | dollars as filed | |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 450,000 | $25,285,500 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 2,599,425 | $24,486,584 | dollars as filed | |
| INSPIRE MED SYS INC COM | 457730109 | Stock | 130,000 | $24,099,400 | dollars as filed | |
| AZENTA INC | 114340102 | COM | 475,000 | $23,750,000 | dollars as filed | |
| EVOLENT HEALTH INC CL A | 30050B101 | Stock | 2,060,000 | $23,175,000 | dollars as filed | |
| ACADIA HEALTHCARE COMPANY INC COM | 00404A109 | Stock | 583,500 | $23,135,775 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 909,103 | $22,518,481 | dollars as filed | |
| WARBY PARKER INC | 93403J106 | CL A COM | 920,000 | $22,273,200 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 487,863 | $20,631,726 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 2,677,996 | $20,138,530 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 767,522 | $19,725,315 | dollars as filed | |
| SUMMIT THERAPEUTICS INC | 86627T108 | COM | 1,054,000 | $18,808,630 | dollars as filed | |
| LIFESTANCE HEALTH GROUP INC | 53228F101 | COM | 2,550,000 | $18,793,500 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 512,132 | $16,664,775 | dollars as filed | |
| TENET HEALTHCARE CORP COM NEW | 88033G407 | Stock | 129,200 | $16,308,916 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 471,086 | $15,479,886 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 6,204,309 | $15,386,686 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 294,100 | $15,037,333 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 775,131 | $14,859,261 | dollars as filed | |
| AGILON HEALTH INC | 00857U107 | COM | 7,463,300 | $14,180,270 | dollars as filed | |
| OSCAR HEALTH INC | 687793109 | CL A | 1,050,000 | $14,112,000 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 328,911 | $11,883,554 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 474,528 | $11,179,880 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 204,466 | $10,947,110 | dollars as filed | |
| INOZYME PHARMA INC | 45790W108 | COM | 3,861,983 | $10,697,693 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 955,106 | $10,124,124 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 463,088 | $9,900,821 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 428,571 | $9,642,848 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 401,013 | $9,215,279 | dollars as filed | |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 742,114 | $9,038,949 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 644,601 | $8,927,724 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 5,779,575 | $8,380,384 | dollars as filed | |
| BICARA THERAPEUTICS INC | 055477103 | COM | 445,975 | $7,768,885 | dollars as filed | |
| ARDELYX INC | 039697107 | COM | 1,463,629 | $7,420,599 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 878,667 | $7,196,283 | dollars as filed | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 252,223 | $6,255,130 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 110,889 | $6,139,924 | dollars as filed | |
| NEVRO CORP | 64157F103 | COM | 1,648,100 | $6,130,932 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 124,095 | $5,578,070 | dollars as filed | |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 404,796 | $5,331,163 | dollars as filed | |
| PULMONX CORP | 745848101 | COM | 772,151 | $5,242,905 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 650,000 | $5,226,000 | dollars as filed | |
| GOSSAMER BIO INC | 38341PAA0 | NOTE 5.000% 6/0 | 9,573,000 | $5,069,861 | dollars as filed | principal |
| Mersana Therapeutics Inc | 59045L106 | Common Stock | 3,431,684 | $4,907,308 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 129,858 | $4,850,196 | dollars as filed | |
| 89BIO INC | 282559103 | COM | 552,741 | $4,322,435 | dollars as filed | |
| CYPHERPUNK TECHNOLOGIES INC | 52187K200 | COM NEW | 1,266,546 | $3,641,320 | dollars as filed | |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 787,808 | $3,545,136 | dollars as filed | |
| EDAP TMS S A | 268311107 | SPONSORED ADR | 1,591,800 | $3,517,878 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 1,053,647 | $3,424,353 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 1,838,916 | $3,162,936 | dollars as filed | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 3,266,960 | $2,955,292 | dollars as filed | |
| Xilio Therapeutics Inc. | 98422T100 | COM | 3,003,259 | $2,868,112 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 80,000 | $2,552,800 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 1,032,988 | $2,427,522 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 95,407 | $2,181,004 | dollars as filed | |
| ALPHATEC HLDGS INC | 02081G201 | COM NEW | 200,000 | $1,836,000 | dollars as filed | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 1,917,191 | $1,641,499 | dollars as filed | |
| COMPUGEN LTD | M25722105 | ORD | 989,990 | $1,514,685 | dollars as filed | |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 444,383 | $1,417,582 | dollars as filed | |
| KORRO BIO INC | 500946108 | COMMON STOCK | 35,719 | $1,359,822 | dollars as filed | |
| ADAPTIMMUNE THERAPEUTICS PLC | 00653A107 | SPONDS ADR | 2,483,468 | $1,337,844 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 1,100,409 | $1,331,495 | dollars as filed | |
| SPRUCE BIOSCIENCES INC | 85209E109 | COM | 2,609,125 | $1,095,833 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 29,305 | $846,035 | dollars as filed | |
| VIGIL NEUROSCIENCE INC | 92673K108 | COM | 471,958 | $802,329 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 181,147 | $702,850 | dollars as filed | |
| KYVERNA THERAPEUTICS INC | 501976104 | COMMON STOCK | 178,963 | $669,322 | dollars as filed | |
| NEVRO CORP | 64157FAC7 | NOTE 2.750% 4/0 | 500,000 | $489,102 | dollars as filed | principal |
| VINCERX PHARMA INC | 92731L106 | COM NEW | 891,719 | $234,344 | dollars as filed | |
| TALPHERA INC | 00444T209 | COM NEW | 316,460 | $165,857 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 134,028 | $30,826 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-25-000867 | this filing | 2025-02-14 | acceptance time not in the bulk data set |