FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 16,534,712 $39M 0.07% +2,500,000 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 9,180,000 $21.7M 0.22% new 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 6,768,206 $16M <0.01% +1,763,770 13F-HR Timeline Group Opaleye Management Inc. More: the full row for Opaleye Management Inc. 6,287,156 $14.8M 1.96% +5,383,714 13F-HR/A Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 4,788,511 $11.3M <0.01% +378,429 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 4,506,861 $10.6M 0.02% +2,684,133 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 4,325,248 $10.2M <0.01% +3,040,286 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 3,981,708 $9.4M <0.01% +1,890,232 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 2,816,291 $6.65M <0.01% +120,313 13F-HR Timeline Group Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 2,351,144 $5.55M 0.4% +251,144 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 2,305,568 $5.44M <0.01% -10,458,665 13F-HR Timeline Group Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 2,000,000 $4.72M 0.24% 0 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 1,954,733 $4.61M <0.01% +107,349 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 1,911,066 $4.51M <0.01% +1,601,370 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 1,711,194 $4.04M <0.01% +1,531,922 13F-HR Timeline Group Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 1,686,000 $3.98M 0.15% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 1,516,435 $3.58M <0.01% +1,178,515 13F-HR/A Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 1,407,699 $3.32M <0.01% +1,297,886 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 1,304,782 $3.08M <0.01% +763,295 13F-HR/A Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 1,093,925 $2.58M <0.01% +842,296 13F-HR Timeline Group GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 951,809 $2.25M 0.73% -1,500,000 13F-HR Timeline 22NW, LP More: the full row for 22NW, LP 820,653 $1.94M 0.9% 0 13F-HR Timeline Velan Capital Investment Management LP More: the full row for Velan Capital Investment Management LP 750,000 $1.77M 1.03% 0 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 737,315 $1.74M <0.01% -35,139 13F-HR Timeline Group KENNEDY CAPITAL MANAGEMENT LLC More: the full row for KENNEDY CAPITAL MANAGEMENT LLC 697,855 $1.65M 0.03% +668,675 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 671,692 $1.59M <0.01% +480,431 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 665,158 $1.57M <0.01% +13,019 13F-HR Timeline Group SUPERSTRING CAPITAL MANAGEMENT LP More: the full row for SUPERSTRING CAPITAL MANAGEMENT LP 513,765 $1.21M 0.65% new 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 481,949 $1.14M 0.03% +457,604 13F-HR Timeline Group HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 374,068 $882K <0.01% new 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 368,166 $869K <0.01% -570,678 13F-HR Timeline Knott David M Jr More: the full row for Knott David M Jr 340,000 $802K 0.37% +65,000 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 296,843 $701K <0.01% new 13F-HR Timeline AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 271,073 $640K <0.01% new 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 249,390 $589K <0.01% new 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 248,679 $587K <0.01% +21,142 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 209,179 $494K 0.12% new 13F-HR/A Timeline PFM Health Sciences, LP More: the full row for PFM Health Sciences, LP 206,265 $487K 0.05% -246,468 13F-HR Timeline Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 150,586 $355K 0.01% new 13F-HR Timeline Group Graham Capital Management, L.P. More: the full row for Graham Capital Management, L.P. 149,952 $354K 0.01% new 13F-HR Timeline Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 147,795 $349K 0.09% new 13F-HR Timeline Group DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 141,883 $335K <0.01% +43,393 13F-HR Timeline Group Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 139,394 $329K <0.01% +86,507 13F-HR Timeline Pavaki Capital Management LLC More: the full row for Pavaki Capital Management LLC 120,000 $283K 0.2% 13F-HR/A Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 97,686 $231K <0.01% -210,650 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 95,968 $226K <0.01% -9,214 13F-HR Timeline Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 93,518 $221K <0.01% new 13F-HR Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 91,461 $216K <0.01% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 89,649 $212K <0.01% +40,513 13F-HR Timeline Group Rangeley Capital, LLC More: the full row for Rangeley Capital, LLC 78,200 $185K 0.16% new 13F-HR Timeline Scientech Research LLC More: the full row for Scientech Research LLC 77,848 $184K 0.12% new 13F-HR Timeline State of Alaska, Department of Revenue More: the full row for State of Alaska, Department of Revenue 77,000 $181K <0.01% new 13F-HR Timeline ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 76,143 $180K <0.01% +33,247 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 72,641 $171K 0.08% new 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 69,373 $164K <0.01% -16,439 13F-HR Timeline Group AlphaCentric Advisors LLC More: the full row for AlphaCentric Advisors LLC 67,056 $158K 0.16% 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 66,641 $157K <0.01% +3,326 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 63,723 $150K <0.01% +2,929 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 63,622 $150K <0.01% new 13F-HR Timeline Decheng Capital LLC More: the full row for Decheng Capital LLC 59,900 $141K 0.02% 0 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 51,821 $122K <0.01% +39,487 13F-HR Timeline LANDSCAPE CAPITAL MANAGEMENT, L.L.C. in group LANDSCAPE CAPITAL MANAGEMENT,… More: the full row for LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 46,413 $110K 0.01% new 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 45,425 $107K <0.01% -314,522 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 45,088 $107K <0.01% +3,630 13F-HR Timeline Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 45,187 $107K <0.01% new 13F-HR Timeline MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 45,084 $105K <0.01% +6,425 13F-HR Timeline Group ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 43,870 $104K <0.01% 0 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 43,819 $103K <0.01% +17,596 13F-HR Timeline MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 42,229 $99.7K <0.01% 0 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 38,679 $91.3K 0.01% -777,296 13F-HR/A Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 37,897 $89.4K <0.01% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 36,948 $87.2K <0.01% +3,747 13F-HR Timeline Group ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 35,301 $83K <0.01% new 13F-HR Timeline Group Pale Fire Capital SE in group Pale Fire Capital More: the full row for Pale Fire Capital SE 33,519 $79.1K 0.01% -8,403 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 32,769 $77.3K <0.01% +29,408 13F-HR Timeline Group GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 27,676 $65.3K <0.01% +26,472 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 25,831 $61K <0.01% -582 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 24,600 $58.1K <0.01% 0 13F-HR Timeline PANAGORA ASSET MANAGEMENT INC More: the full row for PANAGORA ASSET MANAGEMENT INC 22,680 $53.5K <0.01% -143,375 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 21,800 $51.4K <0.01% 0 13F-HR Timeline WINTON GROUP Ltd in group WINTON GROUP Ltd More: the full row for WINTON GROUP Ltd 18,500 $43.7K <0.01% new 13F-HR Timeline Group FOX RUN MANAGEMENT, L.L.C. More: the full row for FOX RUN MANAGEMENT, L.L.C. 17,515 $41.3K 0.01% new 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 16,479 $38.9K 0.01% new 13F-HR Timeline Group Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 15,271 $36K <0.01% new 13F-HR Timeline Group Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 15,000 $35.4K <0.01% new 13F-HR Timeline Group PFG Investments, LLC More: the full row for PFG Investments, LLC 15,000 $35.4K <0.01% new 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 14,757 $34.8K <0.01% +1,529 13F-HR Timeline PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 14,630 $34.5K <0.01% +3,840 13F-HR Timeline Group MML INVESTORS SERVICES, LLC More: the full row for MML INVESTORS SERVICES, LLC 14,625 $34.5K <0.01% +714 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 12,776 $30.2K <0.01% 0 13F-HR Timeline Group HSBC HOLDINGS PLC in group HSBC HOLDINGS PLC More: the full row for HSBC HOLDINGS PLC 12,762 $29.5K <0.01% new 13F-HR/A Timeline Group Fifth Third Wealth Advisors LLC in group FIFTH THIRD BANK, NATIONAL AS… More: the full row for Fifth Third Wealth Advisors LLC 12,135 $28.6K <0.01% new 13F-HR Timeline Group HB Wealth Management, LLC More: the full row for HB Wealth Management, LLC 11,073 $26.1K <0.01% new 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 10,588 $25K <0.01% new 13F-HR Timeline ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 10,510 $24.8K <0.01% new 13F-HR Timeline NIA IMPACT ADVISORS, LLC More: the full row for NIA IMPACT ADVISORS, LLC 10,359 $24.4K 0.01% -1,095 13F-HR Timeline Auxano Advisors, LLC More: the full row for Auxano Advisors, LLC 10,000 $23.6K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 9,209 $21.7K <0.01% +6,740 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 8,264 $19.5K <0.01% -60,863 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 8,115 $19.2K <0.01% -101 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 6,834 $16.1K <0.01% 0 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 6,553 $15.5K <0.01% +33 13F-HR Timeline Group AlphaQuest LLC More: the full row for AlphaQuest LLC 5,992 $14.1K <0.01% -20,768 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 5,531 $14K <0.01% -56,767 13F-HR Timeline Group NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO in group NORTHWESTERN MUTUAL INVESTMEN… More: the full row for NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 5,000 $11.8K <0.01% new 13F-HR/A Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 4,968 $11.7K <0.01% -3,358 13F-HR Timeline NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 3,750 $8.85K <0.01% 0 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 2,649 $6K <0.01% +574 13F-HR Timeline Group AMALGAMATED BANK More: the full row for AMALGAMATED BANK 2,537 $6K <0.01% +251 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 1,188 $2.8K <0.01% +295 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 952 $2.25K <0.01% +903 13F-HR Timeline Caption Management, LLC More: the full row for Caption Management, LLC 600 $1.42K <0.01% -86,201 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 586 $1.38K <0.01% +561 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 390 $921 <0.01% new 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 305 $720 <0.01% -1,695 13F-HR Timeline QUADRANT CAPITAL GROUP LLC More: the full row for QUADRANT CAPITAL GROUP LLC 248 $586 <0.01% 0 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 132 $312 <0.01% -196 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 15 $35 <0.01% new 13F-HR Timeline Arax Advisory Partners More: the full row for Arax Advisory Partners 9 $21 <0.01% -120 13F-HR Timeline Essential Partners LLC More: the full row for Essential Partners LLC 9 $21 <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 8 $19 <0.01% -50 13F-HR Timeline Group SJS Investment Consulting Inc. More: the full row for SJS Investment Consulting Inc. 5 $12 <0.01% new 13F-HR Timeline