FMR LLC in group FMR LLC More: the full row for FMR LLC 5,600,662 $102M 0.01% new 13F-HR Timeline Group a16z Capital Management, L.L.C. in group a16z Capital Management, L.L.… More: the full row for a16z Capital Management, L.L.C. 4,614,574 $84.4M 26.99% new 13F-HR Timeline Group NVP ASSOCIATES, LLC More: the full row for NVP ASSOCIATES, LLC 2,531,000 $46.3M 25.15% new 13F-HR Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 2,426,330 $44.4M 1.67% new 13F-HR Timeline Group LOOMIS SAYLES & CO L P in group LOOMIS SAYLES & CO L P More: the full row for LOOMIS SAYLES & CO L P 1,090,056 $19.9M 0.03% new 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 919,951 $16.8M 1.05% new 13F-HR Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 675,499 $12.4M 0.03% new 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 589,849 $10.8M <0.01% new 13F-HR Timeline Group DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 553,107 $10.1M 0.18% new 13F-HR Timeline Group Sanofi More: the full row for Sanofi 524,903 $9.61M 5.47% new 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 500,000 $9.15M 0.02% new 13F-HR Timeline Group Liberty Street Advisors, Inc. More: the full row for Liberty Street Advisors, Inc. 444,800 $8.14M 9.91% 13F-HR Timeline EMERALD ADVISERS, LLC group of 2 filers holding More: the full row for EMERALD ADVISERS, LLC 439,323 $8.04M new Timeline RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 400,000 $7.32M 0.12% new 13F-HR Timeline Group Avidity Partners Management LP More: the full row for Avidity Partners Management LP 390,600 $7.15M 1.43% new 13F-HR Timeline NEA Management Company, LLC More: the full row for NEA Management Company, LLC 364,115 $6.66M 0.5% new 13F-HR Timeline NORGES BANK More: the full row for NORGES BANK 300,000 $5.49M <0.01% new 13F-HR Timeline Monashee Investment Management LLC More: the full row for Monashee Investment Management LLC 300,000 $5.49M 2.9% new 13F-HR Timeline LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 278,899 $5.1M 0.02% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 278,841 $5.1M <0.01% new 13F-HR Timeline Group Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 257,745 $4.72M 0.02% new 13F-HR Timeline Group JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 250,250 $4.58M <0.01% new 13F-HR Timeline Bellevue Group AG in group Bellevue Group AG More: the full row for Bellevue Group AG 250,000 $4.58M 0.1% new 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 208,286 $3.81M <0.01% new 13F-HR Timeline Group RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 200,000 $3.66M 0.05% new 13F-HR Timeline Fortress Investment Group LLC in group Fortress Investment Group LLC More: the full row for Fortress Investment Group LLC 157,250 $2.88M 0.41% new 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 147,251 $2.69M <0.01% new 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 100,000 $1.83M 0.01% new 13F-HR Timeline Ghisallo Capital Management LLC More: the full row for Ghisallo Capital Management LLC 90,000 $1.65M 0.04% new 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 80,602 $1.48M <0.01% new 13F-HR Timeline Group HBK INVESTMENTS L P More: the full row for HBK INVESTMENTS L P 75,000 $1.37M 0.02% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. Clearline Capital LP More: the full row for Clearline Capital LP 74,041 $1.35M 0.12% new 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 65,000 $1.19M <0.01% new 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 61,400 $1.12M <0.01% new 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 60,500 $1.11M 0.01% new 13F-HR/A Timeline Group GILDER GAGNON HOWE & CO LLC More: the full row for GILDER GAGNON HOWE & CO LLC 57,762 $1.06M 0.01% new 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 54,028 $989K 0.01% new 13F-HR Timeline Burkehill Global Management, LP More: the full row for Burkehill Global Management, LP 50,000 $915K 0.07% new 13F-HR Timeline Davidson Kempner Capital Management LP More: the full row for Davidson Kempner Capital Management LP 45,000 $824K 0.01% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. Longaeva Partners L.P. More: the full row for Longaeva Partners L.P. 42,074 $770K 0.18% new 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 37,858 $693K <0.01% new 13F-HR Timeline Group TEACHER RETIREMENT SYSTEM OF TEXAS More: the full row for TEACHER RETIREMENT SYSTEM OF TEXAS 35,000 $640K <0.01% new 13F-HR Timeline SOROS FUND MANAGEMENT LLC in group SOROS FUND MANAGEMENT LLC More: the full row for SOROS FUND MANAGEMENT LLC 35,000 $640K 0.01% new 13F-HR Timeline Group Freestone Grove Partners LP More: the full row for Freestone Grove Partners LP 35,000 $640K <0.01% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 34,798 $637K <0.01% new 13F-HR Timeline Group SECTORAL ASSET MANAGEMENT INC More: the full row for SECTORAL ASSET MANAGEMENT INC 34,500 $631K 0.42% new 13F-HR Timeline Blackstone Inc. in group Blackstone Inc. More: the full row for Blackstone Inc. 30,000 $549K <0.01% new 13F-HR Timeline Group Limestone Investment Advisors LP More: the full row for Limestone Investment Advisors LP 30,000 $549K 0.24% 13F-HR Timeline Eisler Capital Management Ltd. More: the full row for Eisler Capital Management Ltd. 30,000 $545K 0.02% new 13F-HR Timeline OXFORD ASSET MANAGEMENT LLP More: the full row for OXFORD ASSET MANAGEMENT LLP 29,347 $537K 0.18% new 13F-HR Timeline Weiss Asset Management LP in group Weiss Asset Management LP More: the full row for Weiss Asset Management LP 26,055 $477K 0.01% new 13F-HR Timeline Group The filing omitted confidential holdings, a later amendment may add them. Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 25,000 $458K <0.01% new 13F-HR Timeline Group Pentwater Capital Management LP More: the full row for Pentwater Capital Management LP 24,800 $454K 0.01% new 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 22,628 $414K 0.02% new 13F-HR Timeline Group Sandia Investment Management LP More: the full row for Sandia Investment Management LP 20,000 $366K 0.94% new 13F-HR Timeline HARBERT FUND ADVISORS, LLC More: the full row for HARBERT FUND ADVISORS, LLC 15,000 $274K 0.82% new 13F-HR Timeline Ilex Capital Partners (UK) LLP More: the full row for Ilex Capital Partners (UK) LLP 10,959 $201K 0.01% new 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 10,000 $183K <0.01% new 13F-HR Timeline Group Zimmer Partners, LP More: the full row for Zimmer Partners, LP 10,000 $183K <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 9,945 $182K <0.01% new 13F-HR/A Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 5,300 $97K <0.01% new 13F-HR/A Timeline Group COMERICA BANK More: the full row for COMERICA BANK 3,920 $71.7K <0.01% new 13F-HR Timeline Quarry LP More: the full row for Quarry LP 1,989 $36.4K 0.01% new 13F-HR Timeline RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 1,753 $32.1K <0.01% new 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 477 $8.74K <0.01% new 13F-HR Timeline Group Point72 (DIFC) Ltd More: the full row for Point72 (DIFC) Ltd 475 $8.7K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 276 $5.05K <0.01% new 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 200 $3.66K <0.01% new 13F-HR/A Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 0 $0 0% new 13F-HR Timeline Group Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.