Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 6,795,121 $498M 14.93% 0 13F-HR Timeline JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 4,997,586 $367M 0.17% -238,691 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 3,602,434 $264M <0.01% +25,343 13F-HR Timeline Group VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 2,545,369 $187M <0.01% -19,500 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 2,522,563 $185M 3.04% -114,922 13F-HR Timeline Franklin Resources group of 2 filers holding More: the full row for Franklin Resources 1,604,940 $118M -16,183 Timeline BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 1,495,290 $110M 4.44% -1,266,043 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 1,346,904 $98.7M <0.01% -28,724 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 1,283,288 $94.1M 0.01% -133,927 13F-HR Timeline NOVO HOLDINGS A/S More: the full row for NOVO HOLDINGS A/S 1,264,028 $92.7M 5.97% -236,027 13F-HR Timeline TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 1,236,027 $90.6M 3.49% 0 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 1,040,544 $76.3M 0.06% -365,808 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 1,010,022 $74.1M <0.01% -19,594 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 923,509 $67.7M 0.05% +368,552 13F-HR Timeline Group Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 820,552 $60.2M 0.29% -154,448 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 790,689 $58M 0.01% +672,118 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 790,675 $58M 0.13% +531,809 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 761,126 $55.8M 3.26% -57,080 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 670,149 $49.1M <0.01% +103,823 13F-HR/A Timeline Group LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 661,940 $48.5M 0.14% -109,206 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 640,218 $46.9M <0.01% +580,777 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP group of 2 filers holding More: the full row for TWO SIGMA INVESTMENTS, LP 619,526 $45.4M +276,312 Timeline ARROWSTREET CAPITAL, LIMITED PARTNERSHIP in group ARROWSTREET CAPITAL, LIMITED … More: the full row for ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 612,318 $44.9M 0.03% +536,674 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 601,670 $44.1M 0.01% +11,413 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 601,073 $44.1M 0.03% +119,609 13F-HR Timeline Group EMERALD ADVISERS, LLC group of 2 filers holding More: the full row for EMERALD ADVISERS, LLC 588,638 $43.2M +65,330 Timeline First Turn Management, LLC More: the full row for First Turn Management, LLC 570,569 $41.8M 6.28% +43,029 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 567,894 $41.6M 0.2% 0 13F-HR Timeline Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 541,277 $39.7M 0.04% -159,879 13F-HR Timeline Group LOOMIS SAYLES & CO L P in group LOOMIS SAYLES & CO L P More: the full row for LOOMIS SAYLES & CO L P 539,040 $39.5M 0.05% -13,917 13F-HR Timeline Group BOONE CAPITAL MANAGEMENT LLC More: the full row for BOONE CAPITAL MANAGEMENT LLC 535,732 $39.3M 12.88% -105,716 13F-HR Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 513,448 $37.6M 0.05% +117,100 13F-HR Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 497,468 $36.5M 0.06% +254,468 13F-HR Timeline Group Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 495,976 $36.4M 0.11% +72,232 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 450,838 $33.1M <0.01% +55,830 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 445,527 $32.7M 0.01% -50,534 13F-HR Timeline Group Candriam S.C.A. More: the full row for Candriam S.C.A. 403,026 $29.5M 0.15% +30,021 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 394,489 $28.9M <0.01% +11,329 13F-HR Timeline Group MACQUARIE GROUP LTD in group MACQUARIE GROUP LTD More: the full row for MACQUARIE GROUP LTD 393,212 $28.8M 0.03% -42,505 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 390,474 $28.6M <0.01% +1,204 13F-HR/A Timeline Group VOLORIDGE INVESTMENT MANAGEMENT, LLC More: the full row for VOLORIDGE INVESTMENT MANAGEMENT, LLC 389,574 $28.6M 0.1% +371,999 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 385,336 $28.2M <0.01% -17,060 13F-HR Timeline Group NEXT CENTURY GROWTH INVESTORS LLC More: the full row for NEXT CENTURY GROWTH INVESTORS LLC 360,934 $26.5M 1.93% +170,609 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 346,522 $25.4M 0.04% +2,218 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 336,541 $24.7M -7,405 Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 317,150 $23.3M 0.05% new 13F-HR Timeline Group WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC More: the full row for WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 313,259 $23M 0.06% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 309,031 $22.7M 0.02% +20,872 13F-HR Timeline Group Penn Capital Management Company, LLC More: the full row for Penn Capital Management Company, LLC 307,991 $22.6M 1.74% -34,265 13F-HR Timeline TimesSquare Capital Management, LLC More: the full row for TimesSquare Capital Management, LLC 300,649 $22M 0.32% new 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 278,763 $20.4M 0.02% +31,030 13F-HR Timeline Group AXA Investment Managers S.A. More: the full row for AXA Investment Managers S.A. 255,688 $18.7M 0.05% 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 254,485 $18.7M 0.02% +233,047 13F-HR Timeline Group RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 251,733 $18.5M 0.01% -12,385 13F-HR Timeline Group Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 250,000 $18.2M 0.18% -10,000 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 243,387 $17.8M 0.02% -6,470 13F-HR Timeline Nicholas Investment Partners, LP More: the full row for Nicholas Investment Partners, LP 217,068 $15.9M 1.22% +32,585 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 203,068 $14.9M <0.01% -39,692 13F-HR Timeline Group ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 190,599 $14M 0.23% +31,250 13F-HR/A Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 184,330 $13.5M <0.01% +28,703 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 167,230 $12.3M <0.01% +124,220 13F-HR Timeline Group RICE HALL JAMES & ASSOCIATES, LLC More: the full row for RICE HALL JAMES & ASSOCIATES, LLC 164,746 $12.1M 0.66% -67,247 13F-HR Timeline Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 162,100 $11.9M 0.15% +13,411 13F-HR/A Timeline Group NAN FUNG TRINITY (HK) LTD More: the full row for NAN FUNG TRINITY (HK) LTD 156,265 $11.5M 1.14% +9,500 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 148,696 $10.9M 0.58% -150,000 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 147,252 $10.8M 0.01% +76,545 13F-HR Timeline Group PDT Partners, LLC More: the full row for PDT Partners, LLC 145,379 $10.7M 0.67% 0 13F-HR Timeline FIRST TRUST ADVISORS LP in group FIRST TRUST ADVISORS LP More: the full row for FIRST TRUST ADVISORS LP 144,248 $10.6M 0.01% +14,454 13F-HR Timeline Group Cubist Systematic Strategies, LLC More: the full row for Cubist Systematic Strategies, LLC 144,184 $10.6M 0.15% -766 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 133,973 $9.82M 0.02% 0 13F-HR/A Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 127,903 $9.38M 0.02% +109,626 13F-HR Timeline Group Highlander Partners, L.P. More: the full row for Highlander Partners, L.P. 122,980 $9.02M 3.14% 0 13F-HR Timeline Hennion & Walsh Asset Management, Inc. More: the full row for Hennion & Walsh Asset Management, Inc. 115,854 $8.49M 0.31% -6,915 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 115,771 $8.49M <0.01% -39,100 13F-HR/A Timeline Group ESSEX INVESTMENT MANAGEMENT CO LLC More: the full row for ESSEX INVESTMENT MANAGEMENT CO LLC 113,458 $8.32M 1.27% +727 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 109,959 $8.06M 0.08% +5,656 13F-HR Timeline Patient Square Capital LP More: the full row for Patient Square Capital LP 104,262 $7.64M 2.04% -9,200 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 101,471 $7.44M <0.01% +36,818 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 100,209 $7.35M <0.01% -380,067 13F-HR/A Timeline Group SILVERCREST ASSET MANAGEMENT GROUP LLC More: the full row for SILVERCREST ASSET MANAGEMENT GROUP LLC 90,056 $6.6M 0.04% -45,859 13F-HR Timeline Voleon Capital Management LP More: the full row for Voleon Capital Management LP 86,529 $6.34M 0.15% new 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 78,897 $5.78M 0.01% +12,106 13F-HR Timeline Group 1832 Asset Management L.P. More: the full row for 1832 Asset Management L.P. 75,800 $5.56M 0.01% new 13F-HR Timeline Swiss National Bank More: the full row for Swiss National Bank 72,000 $5.28M <0.01% +1,800 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 64,999 $4.77M 0.01% +33,857 13F-HR Timeline Palo Alto Investors LP More: the full row for Palo Alto Investors LP 64,700 $4.74M 0.88% 0 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 63,946 $4.69M 0.09% +27,049 13F-HR Timeline Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 63,077 $4.55M 0.52% new 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 59,065 $4.33M <0.01% -5,528 13F-HR Timeline BANK OF MONTREAL /CAN/ in group BANK OF MONTREAL /CAN/ More: the full row for BANK OF MONTREAL /CAN/ 57,043 $4.18M <0.01% 0 13F-HR Timeline Group Rhenman & Partners Asset Management AB More: the full row for Rhenman & Partners Asset Management AB 56,255 $4.12M 0.46% -9,500 13F-HR Timeline Jain Global LLC More: the full row for Jain Global LLC 55,601 $4.08M 0.05% new 13F-HR Timeline PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 54,185 $3.97M <0.01% +44,540 13F-HR Timeline Group Eversept Partners, LP More: the full row for Eversept Partners, LP 49,314 $3.62M 0.28% -182,861 13F-HR Timeline Secure Asset Management, LLC More: the full row for Secure Asset Management, LLC 48,441 $3.54M 0.58% -2,556 13F-HR Timeline Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 45,052 $3.3M <0.01% -113,976 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 43,450 $3.19M <0.01% 0 13F-HR Timeline Calamos Advisors LLC in group Calamos Advisors LLC More: the full row for Calamos Advisors LLC 43,250 $3.17M 0.01% +9,985 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 39,832 $2.92M <0.01% +14,295 13F-HR Timeline Group CAPITAL FUND MANAGEMENT S.A. More: the full row for CAPITAL FUND MANAGEMENT S.A. 36,115 $2.65M 0.03% +6,840 13F-HR Timeline Legato Capital Management LLC More: the full row for Legato Capital Management LLC 34,567 $2.53M 0.28% +2,804 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 33,127 $2.43M 0.01% -4,080 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 33,125 $2.43M <0.01% -449 13F-HR Timeline AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 31,395 $2.3M <0.01% -16,121 13F-HR Timeline Group State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 30,800 $2.26M 0.01% new 13F-HR Timeline Group F/m Investments LLC More: the full row for F/m Investments LLC 29,806 $2.19M 0.08% +1,250 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 28,490 $2.09M <0.01% +5,697 13F-HR Timeline Group TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 27,654 $2.03M 0.01% new 13F-HR/A Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 27,065 $1.98M <0.01% -171,095 13F-HR Timeline Group HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 26,697 $1.96M 0.01% new 13F-HR Timeline Penserra Capital Management LLC in group Penserra Capital Management L… More: the full row for Penserra Capital Management LLC 26,479 $1.94M 0.02% +18,746 13F-HR Timeline Group LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 25,932 $1.9M 0.01% +17,380 13F-HR Timeline ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 24,023 $1.76M 0.01% -2,613 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 23,606 $1.73M <0.01% -28,804 13F-HR Timeline Group Campbell & CO Investment Adviser LLC More: the full row for Campbell & CO Investment Adviser LLC 23,566 $1.73M 0.13% new 13F-HR Timeline MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 23,474 $1.72M 0.01% -2,473 13F-HR Timeline Group PRINCIPAL FINANCIAL GROUP INC in group PRINCIPAL FINANCIAL GROUP INC More: the full row for PRINCIPAL FINANCIAL GROUP INC 22,440 $1.65M <0.01% -8,980 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 22,386 $1.64M -5,172 Timeline CANADA PENSION PLAN INVESTMENT BOARD More: the full row for CANADA PENSION PLAN INVESTMENT BOARD 20,696 $1.52M <0.01% new 13F-HR Timeline Knights of Columbus Asset Advisors LLC More: the full row for Knights of Columbus Asset Advisors LLC 20,115 $1.47M 0.08% +847 13F-HR Timeline Ascentis Independent Advisors in group Ascentis Wealth Management, L… More: the full row for Ascentis Independent Advisors 19,380 $1.42M 0.24% 0 13F-HR Timeline Group Values First Advisors, Inc. More: the full row for Values First Advisors, Inc. 18,712 $1.37M 0.73% -920 13F-HR Timeline OAK RIDGE INVESTMENTS LLC More: the full row for OAK RIDGE INVESTMENTS LLC 17,758 $1.3M 0.08% -357 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 17,188 $1.26M 0.01% -3,651 13F-HR Timeline Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 17,018 $1.25M 0.01% +12,368 13F-HR Timeline COMMONWEALTH EQUITY SERVICES, LLC More: the full row for COMMONWEALTH EQUITY SERVICES, LLC 16,231 $1.19M <0.01% +472 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 15,604 $1.14M <0.01% +6,902 13F-HR Timeline Group TD Asset Management Inc More: the full row for TD Asset Management Inc 15,400 $1.13M <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 15,260 $1.12M <0.01% +8,654 13F-HR Timeline Group TEACHERS RETIREMENT SYSTEM OF THE STATE… More: the full row for TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 14,724 $1.08M 0.01% new 13F-HR Timeline POLEN CAPITAL MANAGEMENT LLC More: the full row for POLEN CAPITAL MANAGEMENT LLC 13,339 $978K <0.01% -2,168 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 13,243 $971K <0.01% -91 13F-HR Timeline Virtus Investment Advisers, LLC group of 2 filers holding More: the full row for Virtus Investment Advisers, LLC 13,066 $958K +4,000 Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 12,744 $934K <0.01% +3,527 13F-HR Timeline Group STRS OHIO More: the full row for STRS OHIO 12,700 $931K <0.01% +9,000 13F-HR Timeline AlphaQuest LLC More: the full row for AlphaQuest LLC 12,585 $923K 0.06% +2,802 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 12,115 $888K <0.01% -84 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 11,347 $832K 0.01% +1,325 13F-HR Timeline Y-Intercept (Hong Kong) Ltd More: the full row for Y-Intercept (Hong Kong) Ltd 11,025 $808K 0.02% new 13F-HR Timeline ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 10,984 $805K <0.01% +275 13F-HR Timeline WOLVERINE ASSET MANAGEMENT LLC in group WOLVERINE ASSET MANAGEMENT LLC More: the full row for WOLVERINE ASSET MANAGEMENT LLC 10,670 $782K 0.01% new 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 10,401 $762K 0.01% new 13F-HR Timeline Group OMERS ADMINISTRATION Corp More: the full row for OMERS ADMINISTRATION Corp 10,100 $740K 0.01% new 13F-HR Timeline DARK FOREST CAPITAL MANAGEMENT LP More: the full row for DARK FOREST CAPITAL MANAGEMENT LP 10,082 $739K 0.03% -6,394 13F-HR/A Timeline CAPSTONE INVESTMENT ADVISORS, LLC in group CAPSTONE INVESTMENT ADVISORS,… More: the full row for CAPSTONE INVESTMENT ADVISORS, LLC 10,004 $733K 0.01% new 13F-HR Timeline Group Atle Fund Management AB More: the full row for Atle Fund Management AB 93,605 $729K 2.7% -13,307 13F-HR Timeline TEACHER RETIREMENT SYSTEM OF TEXAS More: the full row for TEACHER RETIREMENT SYSTEM OF TEXAS 9,083 $666K <0.01% -820 13F-HR Timeline NEOS Investment Management LLC More: the full row for NEOS Investment Management LLC 8,957 $657K <0.01% -990 13F-HR Timeline Tema ETFs LLC More: the full row for Tema ETFs LLC 8,957 $657K 0.05% -990 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 8,806 $646K 0.05% -1,143 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 8,692 $637K <0.01% -2,073 13F-HR Timeline CenterBook Partners LP More: the full row for CenterBook Partners LP 8,357 $613K 0.03% new 13F-HR Timeline GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 8,251 $605K 0.05% -18,800 13F-HR Timeline Jasper Ridge Partners, L.P. More: the full row for Jasper Ridge Partners, L.P. 8,206 $602K 0.01% 0 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 7,947 $583K <0.01% 0 13F-HR Timeline EntryPoint Capital, LLC More: the full row for EntryPoint Capital, LLC 7,878 $578K 0.22% +612 13F-HR Timeline Semanteon Capital Management, LP More: the full row for Semanteon Capital Management, LP 7,653 $561K 0.7% new 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 7,600 $557K <0.01% 0 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 7,576 $555K 0.02% -611 13F-HR Timeline Aigen Investment Management, LP More: the full row for Aigen Investment Management, LP 7,349 $539K 0.08% +845 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 7,317 $536K <0.01% new 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 7,018 $514K <0.01% new 13F-HR Timeline Group Reliant Investment Partners, LLC More: the full row for Reliant Investment Partners, LLC 6,975 $509K 0.4% 0 13F-HR Timeline WEALTH ENHANCEMENT ADVISORY SERVICES, L… More: the full row for WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 6,899 $509K <0.01% -4,946 13F-HR Timeline Baader Bank Aktiengesellschaft More: the full row for Baader Bank Aktiengesellschaft 6,895 $503K 0.04% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. ENVESTNET ASSET MANAGEMENT INC in group ENVESTNET ASSET MANAGEMENT INC More: the full row for ENVESTNET ASSET MANAGEMENT INC 6,802 $499K <0.01% +1,473 13F-HR Timeline Group Universal- Beteiligungs- und Serviceges… in group Universal- Beteiligungs- und … More: the full row for Universal- Beteiligungs- und Servicegesellschaft mbH 6,574 $482K <0.01% +1,848 13F-HR Timeline Group GREAT LAKES ADVISORS, LLC More: the full row for GREAT LAKES ADVISORS, LLC 6,465 $474K <0.01% 0 13F-HR Timeline Bryce Point Capital, LLC More: the full row for Bryce Point Capital, LLC 6,319 $463K 0.57% new 13F-HR Timeline OXFORD ASSET MANAGEMENT LLP More: the full row for OXFORD ASSET MANAGEMENT LLP 5,864 $430K 0.14% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. Magnetar Financial LLC in group Magnetar Financial LLC More: the full row for Magnetar Financial LLC 5,736 $421K <0.01% new 13F-HR Timeline Group FORA Capital, LLC More: the full row for FORA Capital, LLC 5,140 $377K 0.07% new 13F-HR Timeline CONTRAVISORY INVESTMENT MANAGEMENT, INC. More: the full row for CONTRAVISORY INVESTMENT MANAGEMENT, INC. 5,127 $376K 0.07% -180 13F-HR Timeline Point72 Hong Kong Ltd More: the full row for Point72 Hong Kong Ltd 4,986 $366K 0.02% new 13F-HR Timeline Caprock Group, LLC More: the full row for Caprock Group, LLC 4,778 $353K 0.01% 13F-HR Timeline Cetera Investment Advisers More: the full row for Cetera Investment Advisers 4,438 $325K <0.01% new 13F-HR Timeline Graham Capital Management, L.P. More: the full row for Graham Capital Management, L.P. 4,321 $317K 0.01% -5,405 13F-HR Timeline CIBC Bancorp USA Inc. in group CIBC Bancorp USA Inc. More: the full row for CIBC Bancorp USA Inc. 4,303 $315K <0.01% 13F-HR/A Timeline Group PUBLIC EMPLOYEES RETIREMENT ASSOCIATION… More: the full row for PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 4,292 $315K <0.01% new 13F-HR Timeline Palumbo Wealth Management LLC More: the full row for Palumbo Wealth Management LLC 4,242 $311K 0.1% -1,362 13F-HR Timeline Man Group plc in group Man Group plc More: the full row for Man Group plc 3,960 $290K <0.01% -15,847 13F-HR Timeline Group RWC Asset Management LLP in group RWC ASSET ADVISORS (US) LLC More: the full row for RWC Asset Management LLP 3,797 $278K 0.01% new 13F-HR Timeline Group MACKENZIE FINANCIAL CORP More: the full row for MACKENZIE FINANCIAL CORP 3,787 $278K <0.01% new 13F-HR Timeline PharVision Advisers, LLC More: the full row for PharVision Advisers, LLC 3,724 $273K 0.15% new 13F-HR Timeline Ballentine Partners, LLC More: the full row for Ballentine Partners, LLC 3,580 $262K <0.01% new 13F-HR Timeline Sigma Planning Corp More: the full row for Sigma Planning Corp 3,400 $249K 0.01% new 13F-HR Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 3,372 $247K 0.01% -1,067 13F-HR Timeline Group Glenmede Investment Management, LP More: the full row for Glenmede Investment Management, LP 3,315 $243K <0.01% new 13F-HR Timeline VIRGINIA RETIREMENT SYSTEMS ET Al More: the full row for VIRGINIA RETIREMENT SYSTEMS ET Al 3,200 $235K <0.01% new 13F-HR Timeline FOX RUN MANAGEMENT, L.L.C. More: the full row for FOX RUN MANAGEMENT, L.L.C. 3,158 $232K 0.04% new 13F-HR Timeline XPONANCE LLC More: the full row for XPONANCE LLC 3,151 $231K <0.01% new 13F-HR Timeline Brookwood Investment Group LLC More: the full row for Brookwood Investment Group LLC 3,100 $227K 0.03% new 13F-HR Timeline OPPENHEIMER ASSET MANAGEMENT INC. in group OPPENHEIMER ASSET MANAGEMENT … More: the full row for OPPENHEIMER ASSET MANAGEMENT INC. 3,074 $225K <0.01% new 13F-HR Timeline Group Avanza Fonder AB More: the full row for Avanza Fonder AB 3,030 $222K 0.01% -1,124 13F-HR Timeline LANARK FINANCIAL, INC. More: the full row for LANARK FINANCIAL, INC. 3,017 $221K 0.02% +140 13F-HR Timeline Atria Investments, Inc More: the full row for Atria Investments, Inc 3,001 $220K <0.01% new 13F-HR Timeline Janney Montgomery Scott LLC More: the full row for Janney Montgomery Scott LLC 3,000 $220K <0.01% new 13F-HR Timeline FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 3,000 $220K <0.01% new 13F-HR/A Timeline Concurrent Investment Advisors, LLC in group Concurrent Investment Advisor… More: the full row for Concurrent Investment Advisors, LLC 3,000 $220K <0.01% new 13F-HR Timeline Group Longboard Asset Management, LP More: the full row for Longboard Asset Management, LP 2,920 $214K 0.35% new 13F-HR Timeline