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Disclosery

LYEL LYELL IMMUNOPHARMA INC

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Stock (common), issuer CIK 1806952

68 managers (73 13F filers) reported a position in LYEL shares at 2026-03-31, 11,974,545 shares in all. 14 filers opened a position and 9 filers sold out during the quarter.

Managers
68
13F filers
73
New
14
Added
24
Reduced
8
Sold out
9
Shares held by filers
11,974,545

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
Aguirre Jarrad Mattieuofficer (Chief Medical Officer)2026-10-12-422 S$8.63Form 4

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ARCH Venture Management, LLC3,247,162$65.1M9.62%+488,09013F-HRTimeline
GSK plc1,512,659$30.3M5.06%013F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding1,277,477$25.6M0Timeline
VANGUARD GROUP INCgroup of 4 filers holding833,260$16.7MnewTimeline
Orland Properties Ltdin group Orland Properties Ltd754,698$15.1M5.67%013F-HRTimelineGroup
Almitas Capital LLC577,807$11.6M2.62%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC458,905$9.21M0.01%+400,25413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC381,462$7.65M0.01%+56,76113F-HRTimelineGroup
venBio Partners LLC337,697$6.77M2.41%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding330,998$6.64M+159,182Timeline
Alphabet Inc.in group Alphabet Inc.293,256$5.88M0.15%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.191,820$3.85M<0.01%+9,98313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC166,980$3.35M<0.01%+3,98313F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP148,516$2.98M<0.01%+75,20113F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC116,411$2.34M<0.01%+76,92113F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC114,491$2.3M<0.01%+17,81613F-HRTimelineGroup
Velan Capital Investment Management LP102,000$2.05M1.28%new13F-HRTimeline
MIC Capital Management UK LLP87,028$1.75M0.5%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co85,971$1.72M<0.01%+54813F-HRTimelineGroup
Opaleye Management Inc.79,097$1.59M0.21%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP72,522$1.45M<0.01%+21,05013F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC63,893$1.28M<0.01%+51,48413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY56,151$1.13M<0.01%+13,20213F-HRTimelineGroup
Qube Research & Technologies Ltd55,110$1.11M<0.01%+46,05913F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP47,888$959K<0.01%new13F-HRTimelineGroup
RBF Capital, LLC44,094$885K0.04%-30,49113F-HR/ATimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC41,081$824K0.12%013F-HRTimelineGroup
Clearstead Advisors, LLC39,916$801K0.01%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/33,321$668K<0.01%+25,27613F-HRTimelineGroup
UBS Group AGin group UBS Group AG31,814$638K<0.01%+18,61113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP30,280$607K<0.01%013F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD29,411$590K<0.01%-2,70013F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC22,207$445K<0.01%new13F-HR/ATimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.21,292$427K<0.01%+9,81213F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC20,123$404K0.01%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC19,294$387K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC18,000$361K0.01%013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC15,971$320K<0.01%new13F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…13,435$270K<0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/13,128$264K<0.01%013F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP11,585$232K<0.01%-4,03113F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC5,912$119K<0.01%+1,67913F-HRTimelineGroup
China Universal Asset Management Co., L…3,770$75.6K0.01%+31313F-HRTimeline
HSG Holding Ltdin group HSG Holding Ltd152,299$73.1K<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,097$42.1K<0.01%-1,07313F-HRTimelineGroup
FMR LLCin group FMR LLC1,823$36.6K<0.01%-613F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC1,671$33.5K<0.01%-14,29613F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,468$28.3K<0.01%-14813F-HR/ATimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,301$26.1K<0.01%+10713F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…1,108$22.2K<0.01%+7713F-HR/ATimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,025$20.2K<0.01%013F-HRTimelineGroup
SIMPLEX TRADING, LLC693$13.9K<0.01%+65613F-HRTimeline
IFP Advisors, Inc648$13K<0.01%new13F-HRTimeline
Advisors Asset Management, Inc.567$11.4K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.470$9.43K<0.01%+5413F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…447$8.97K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA251$6K<0.01%+22713F-HRTimelineGroup
Seneschal Advisors, LLC126$2.53K<0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN125$2.51K<0.01%013F-HR/ATimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.124$2.49K<0.01%013F-HRTimelineGroup
GROUP ONE TRADING LLC100$2.01K<0.01%new13F-HRTimeline
MAI Capital Management100$2.01K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\58$1.16K<0.01%013F-HRTimelineGroup
Cornerstone Financial Management LLC46$923<0.01%013F-HR/ATimeline
Allworth Financial LP43$863<0.01%new13F-HRTimeline
GAMMA Investing LLC35$702<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC25$502<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC2$40<0.01%-1813F-HRTimelineGroup

Events

  • Aguirre Jarrad Mattieu sold 422 LYEL shares on 2026-10-12, Form 4 filed 2026-10-13. 0002150331-26-000003

    Accepted , ingested