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Disclosery

LYEL LYELL IMMUNOPHARMA INC

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Stock (common), issuer CIK 1806952

55 managers (57 13F filers) reported a position in LYEL shares at 2025-09-30, 9,650,090 shares in all. 7 filers opened a position and 14 filers sold out during the quarter.

Managers
55
13F filers
57
New
7
Added
17
Reduced
17
Sold out
14
Shares held by filers
9,650,090

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
Aguirre Jarrad Mattieuofficer (Chief Medical Officer)2026-10-12-422 S$8.63Form 4

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ARCH Venture Management, LLC2,759,072$44.8M9.1%+938,43813F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding1,277,477$20.7M+70,426Timeline
MWG Management Ltd.1,008,116$16.4M20.13%new13F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC779,004$12.7M<0.01%+336,37813F-HRTimelineGroup
Orland Properties Ltdin group Orland Properties Ltd754,698$12.3M2.62%new13F-HRTimelineGroup
Almitas Capital LLC577,807$9.38M2.15%-2,19013F-HR/ATimeline
venBio Partners LLC473,479$7.69M4.36%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC339,491$5.51M<0.01%+68,20813F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.293,256$4.76M0.2%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.176,806$2.87M<0.01%+31,94713F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC130,257$2.12M<0.01%+26,98713F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC125,361$2.04M<0.01%+73,13213F-HRTimelineGroup
RBF Capital, LLC95,631$1.55M0.07%-4,36913F-HRTimeline
MIC Capital Management UK LLP87,028$1.41M0.28%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co79,510$1.29M<0.01%+18,00713F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC63,990$1.04M<0.01%-3,20013F-HRTimeline
JOHNSON & JOHNSONin group JOHNSON & JOHNSON54,887$891K0.18%new13F-HR/ATimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC51,727$840K0.02%013F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC43,799$711K0.14%013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY37,020$601K<0.01%+11,32213F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding36,959$600K+15,259Timeline
STATE STREET CORPin group STATE STREET CORP33,752$548K<0.01%-9513F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD29,411$478K<0.01%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP28,128$457K<0.01%+9,48413F-HRTimelineGroup
UBS Group AGin group UBS Group AG21,242$345K<0.01%-4,39213F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP20,827$338K<0.01%+10,76813F-HRTimelineGroup
Clarius Group, LLC19,958$324K0.02%+82013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC18,000$292K0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/13,128$214K<0.01%-292,93113F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC12,234$199K0.01%013F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC11,390$184K<0.01%-15,97613F-HRTimelineGroup
Trexquant Investment LP10,275$167K<0.01%new13F-HRTimeline
Rangeley Capital, LLC10,000$162K0.15%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/4,679$76K<0.01%-19,07913F-HR/ATimelineGroup
HSG Holding Ltdin group HSG Holding Ltd152,299$73.1K<0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,187$68K<0.01%+4,16213F-HRTimelineGroup
China Universal Asset Management Co., L…3,367$54.7K<0.01%+40113F-HRTimeline
FMR LLCin group FMR LLC2,722$44.2K<0.01%-35513F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,858$30.2K<0.01%-24513F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,000$25.7K<0.01%013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC1,192$19.4K<0.01%+3713F-HR/ATimelineGroup
CITIGROUP INCin group CITIGROUP INC1,030$16.7K<0.01%-1,02513F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…743$12.1K<0.01%+17313F-HRTimelineGroup
Advisors Asset Management, Inc.567$9.21K<0.01%-813F-HR/ATimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO490$7.96K<0.01%-2,87913F-HR/ATimelineGroup
GF FUND MANAGEMENT CO. LTD.413$6.71K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS355$5.76K<0.01%+213F-HRTimelineGroup
SIMPLEX TRADING, LLC162$2K<0.01%-13613F-HRTimeline
MAI Capital Management100$1.62K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.45$1K<0.01%013F-HRTimelineGroup
CWM, LLCin group CWM, LLC42$1K<0.01%-37313F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\58$942<0.01%013F-HRTimelineGroup
GAMMA Investing LLC35$568<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC25$406<0.01%013F-HRTimeline
IFP Advisors, Inc1$16<0.01%-213F-HR/ATimeline

Events

  • Aguirre Jarrad Mattieu sold 422 LYEL shares on 2026-10-12, Form 4 filed 2026-10-13. 0002150331-26-000003

    Accepted , ingested