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Disclosery

LYEL LYELL IMMUNOPHARMA INC

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Stock (common), issuer CIK 1806952

65 managers (67 13F filers) reported a position in LYEL shares at 2025-12-31, 11,405,527 shares in all. 12 filers opened a position and 4 filers sold out during the quarter.

Managers
65
13F filers
67
New
12
Added
17
Reduced
16
Sold out
4
Shares held by filers
11,405,527

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
Aguirre Jarrad Mattieuofficer (Chief Medical Officer)2026-10-12-422 S$8.63Form 4

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ARCH Venture Management, LLC2,759,072$84.9M13.03%013F-HRTimeline
GSK plc1,512,659$46.6M5.83%13F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding1,277,477$39.3M0Timeline
MWG Caph Ltd1,008,116$31M42.88%13F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC826,430$25.4M<0.01%+47,42613F-HRTimelineGroup
Orland Properties Ltdin group Orland Properties Ltd754,698$23.2M4.35%013F-HRTimelineGroup
Almitas Capital LLC577,807$17.8M3.92%013F-HRTimeline
venBio Partners LLC337,697$10.4M4.81%-135,78213F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC324,701$9.99M0.01%-14,79013F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.293,256$9.03M0.35%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.181,837$5.6M<0.01%+5,03113F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding171,816$5.29M+134,857Timeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC162,997$5.02M<0.01%+32,74013F-HRTimelineGroup
HSG Holding Ltdin group HSG Holding Ltd152,299$3.94M0.21%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.98,649$3.04M<0.01%new13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC96,675$2.98M<0.01%new13F-HR/ATimelineGroup
MIC Capital Management UK LLP87,028$2.68M0.61%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co85,423$2.63M<0.01%+5,91313F-HRTimelineGroup
RBF Capital, LLC74,585$2.3M0.1%-21,04613F-HR/ATimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP73,315$2.26M<0.01%new13F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC58,651$1.81M<0.01%-66,71013F-HRTimelineGroup
JOHNSON & JOHNSONin group JOHNSON & JOHNSON54,887$1.69M0.3%013F-HR/ATimelineGroup
STATE STREET CORPin group STATE STREET CORP51,472$1.58M<0.01%+17,72013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY42,949$1.32M<0.01%+5,92913F-HR/ATimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC41,081$1.26M0.16%-2,71813F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC39,490$1.22M<0.01%-24,50013F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD32,111$988K<0.01%+2,70013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP30,280$932K<0.01%+2,15213F-HRTimelineGroup
Clarius Group, LLC19,958$614K0.04%013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC18,000$554K0.01%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC15,967$491K<0.01%+14,77513F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP15,616$481K<0.01%-5,21113F-HRTimelineGroup
UBS Group AGin group UBS Group AG13,203$406K<0.01%-8,03913F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/13,128$405K<0.01%013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC12,409$382K<0.01%new13F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.11,480$353K<0.01%new13F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC9,516$293K0.01%-2,71813F-HRTimeline
Qube Research & Technologies Ltd9,051$279K<0.01%new13F-HRTimeline
ExodusPoint Capital Management, LP8,511$262K<0.01%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/8,045$248K<0.01%+3,36613F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC7,900$243K<0.01%new13F-HRTimelineGroup
Candriam S.C.A.7,617$234K<0.01%new13F-HR/ATimeline
BBR PARTNERS, LLC6,834$210K0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC4,233$130K<0.01%+3,20313F-HRTimelineGroup
China Universal Asset Management Co., L…3,457$106K0.01%+9013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS3,170$97.6K<0.01%+2,81513F-HRTimelineGroup
FMR LLCin group FMR LLC1,829$56.3K<0.01%-89313F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC1,657$51K<0.01%-9,73313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,616$49.7K<0.01%+1,12613F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,194$36.8K<0.01%-66413F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…1,031$31.7K<0.01%+28813F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,025$31.6K<0.01%-97513F-HRTimelineGroup
Advisors Asset Management, Inc.567$17.5K<0.01%013F-HR/ATimeline
GF FUND MANAGEMENT CO. LTD.416$12.8K<0.01%+313F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN125$3.85K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.124$3.82K<0.01%new13F-HRTimelineGroup
MAI Capital Management100$3.08K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\58$1.78K<0.01%013F-HRTimelineGroup
Cornerstone Financial Management LLC46$1.42K<0.01%13F-HR/ATimeline
SIMPLEX TRADING, LLC37$1.14K<0.01%-12513F-HRTimeline
GAMMA Investing LLC35$1.08K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.45$1K<0.01%013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA24$1K<0.01%-4,16313F-HRTimelineGroup
CWM, LLCin group CWM, LLC20$1K<0.01%-2213F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC25$770<0.01%013F-HRTimeline

Events

  • Aguirre Jarrad Mattieu sold 422 LYEL shares on 2026-10-12, Form 4 filed 2026-10-13. 0002150331-26-000003

    Accepted , ingested