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Disclosery

ANNX ANNEXON INC

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COM (common), issuer CIK 1528115

165 managers (168 13F filers) reported a position in ANNX shares at 2025-12-31, 136,904,584 shares in all. 39 filers opened a position and 14 filers sold out during the quarter.

Managers
165
13F filers
168
New
39
Added
72
Reduced
30
Sold out
14
Shares held by filers
136,904,584

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC10,222,470$51.3M<0.01%-858,69313F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC10,050,644$50.5M3.72%+3,750,00013F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL9,128,080$45.8M1.54%+2,128,08013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.8,960,434$45M<0.01%+1,061,42613F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding7,766,288$39M+1,917,932Timeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…5,500,000$27.6M0.04%+4,000,00013F-HRTimelineGroup
Bain Capital Life Sciences Investors, L…in group Bain Capital Life Sciences In…5,249,069$26.4M2.02%013F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG5,157,290$25.9M0.49%013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,652,185$23.4M<0.01%+2,601,87713F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC4,348,782$21.8M<0.01%+2,156,42813F-HRTimelineGroup
Woodline Partners LP4,000,074$20.1M0.08%+1,361,79913F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management3,299,256$16.6M0.03%+2,001,99613F-HRTimelineGroup
Longaeva Partners L.P.3,100,000$15.6M1.85%new13F-HRTimeline
MAK CAPITAL ONE LLC2,958,527$14.9M2%new13F-HRTimeline
Nuveen, LLCin group TIAA2,915,324$14.6M<0.01%+2,232,76613F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,902,896$14.6M<0.01%+465,95213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,856,143$14.3M<0.01%-173,70513F-HR/ATimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC2,836,857$14.2M0.01%+14,03413F-HRTimelineGroup
Opaleye Management Inc.2,600,000$13.1M1.72%013F-HR/ATimeline
Palo Alto Investors LP2,384,192$12M1.67%new13F-HRTimeline
Qube Research & Technologies Ltd2,381,479$12M0.02%+1,808,83513F-HRTimeline
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd2,032,455$10.2M2.15%-80,00013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,768,745$8.88M<0.01%-637,68713F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,605,581$8.06M<0.01%+311,27913F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.1,316,212$6.61M1.38%-478,17513F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,057,060$5.31M<0.01%+266,81013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,046,221$5.25M<0.01%new13F-HRTimelineGroup
J. Goldman & Co LP993,795$4.99M0.19%-113,20613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.972,449$4.88M<0.01%+770,50413F-HRTimelineGroup
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…903,439$4.54M<0.01%-76,84613F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC861,245$4.32M0.01%+328,88213F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC802,600$4.03M0.01%+49,02113F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP792,000$3.98M<0.01%+4,29213F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC776,307$3.9M<0.01%+202,18413F-HRTimelineGroup
Ishara Investments LP750,000$3.77M4.38%13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP718,680$3.61M<0.01%-48,27513F-HRTimelineGroup
SIRIOS CAPITAL MANAGEMENT L P710,256$3.57M0.44%-259,94413F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC683,879$3.43M0.01%+661,29013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…683,016$3.43M<0.01%+664,79613F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…642,038$3.22M0.03%-424,89413F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC639,902$3.21M0.07%-55813F-HRTimeline
Parkman Healthcare Partners LLC601,202$3.02M0.29%+195,24913F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…583,913$2.93M0.04%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN573,748$2.88M<0.01%+164,27113F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\560,744$2.81M<0.01%-943,60513F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding542,127$2.72M+37,133Timeline
Hennion & Walsh Asset Management, Inc.534,986$2.69M0.09%+59,05713F-HRTimeline
Schonfeld Strategic Advisors LLC522,846$2.62M0.01%+310,62713F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP520,998$2.62M<0.01%new13F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC513,836$2.58M<0.01%+294,34213F-HRTimelineGroup
Board of Trustees of The Leland Stanfor…482,550$2.42M0.49%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/445,074$2.23M<0.01%-39,70113F-HRTimeline
SummitTX Capital, L.P.438,497$2.2M0.07%+196,50613F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…398,077$2M<0.01%new13F-HRTimelineGroup
UBS Group AGin group UBS Group AG377,104$1.89M<0.01%+30,96513F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.371,190$1.86M<0.01%+281,14113F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp361,677$1.82M<0.01%+53,48913F-HRTimelineGroup
Cinctive Capital Management LP358,986$1.8M0.1%+293,52013F-HRTimeline
DIADEMA PARTNERS LP350,000$1.76M1.05%new13F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding332,038$1.67M+29,104Timeline
BARCLAYS PLCin group BARCLAYS PLC289,963$1.46M<0.01%+142,03313F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC275,294$1.38M<0.01%+107,79413F-HRTimelineGroup
DAFNA Capital Management LLC272,812$1.37M0.32%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC251,158$1.26M<0.01%+14,42213F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd243,313$1.22M0.03%+95,47313F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC230,244$1.16M0.15%new13F-HRTimelineGroup
IEQ CAPITAL, LLC182,982$919K<0.01%+32,66013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.147,375$740K<0.01%013F-HRTimelineGroup
Rafferty Asset Management, LLC141,644$711K<0.01%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.140,740$707K<0.01%013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC137,800$692K0.01%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …130,102$655K<0.01%-2,57113F-HRTimelineGroup
RHUMBLINE ADVISERS126,463$635K<0.01%-6,14013F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…123,753$621K0.01%+29,19913F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC122,858$617K0.01%new13F-HRTimelineGroup
Caption Management, LLC119,491$600K0.03%new13F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS118,324$594K<0.01%+33,80113F-HRTimelineGroup
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG117,768$591K0.01%-105,45313F-HRTimelineGroup
Persistent Asset Partners Ltd93,657$470K0.23%new13F-HRTimeline
Quarry LP75,000$376K0.06%-35,00013F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC64,069$322K0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding61,796$310K+12,569Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS61,572$309K<0.01%+41,83313F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO58,259$292K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO53,729$270K<0.01%+6,84313F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…53,527$269K0.07%+11,54013F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd53,400$268K0.01%new13F-HRTimelineGroup
PROFUND ADVISORS LLC53,008$266K0.01%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd48,573$244K<0.01%new13F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC48,000$241K0.02%new13F-HR/ATimelineGroup
TD Asset Management Inc46,848$235K<0.01%013F-HRTimeline
Allegheny Financial Group42,900$215K0.03%013F-HRTimeline
EntryPoint Capital, LLC42,774$215K0.08%+22,80313F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC42,524$213K<0.01%+15,84813F-HRTimeline
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…40,000$201K<0.01%013F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…39,059$196K<0.01%-5,57313F-HRTimelineGroup
Pale Fire Capital SEin group Pale Fire Capital38,600$194K0.02%new13F-HRTimelineGroup
China Universal Asset Management Co., L…36,084$181K0.01%+82313F-HRTimeline
Landing Point Financial Group, LLC34,900$175K0.09%new13F-HRTimeline
COMERICA BANK32,357$162K<0.01%013F-HRTimeline
CAPTRUST FINANCIAL ADVISORS31,585$159K<0.01%new13F-HRTimeline
Mariner, LLCin group Mariner, LLC31,335$157K<0.01%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC30,297$152K<0.01%+6,80913F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND29,568$148K<0.01%-4,91113F-HRTimeline
AXQ CAPITAL, LP29,108$146K0.03%+1,24113F-HRTimeline
Police & Firemen's Retirement System of…28,105$141K<0.01%013F-HRTimeline
SG Americas Securities, LLC28,071$141K<0.01%+17,07413F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC25,651$130K<0.01%-7013F-HR/ATimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC24,869$125K<0.01%+4,86913F-HRTimelineGroup
ProShare Advisors LLC24,698$124K<0.01%+4,41013F-HRTimeline
Creative Planningin group Creative Planning24,004$120K<0.01%+8,55313F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC23,640$119K<0.01%+16,81213F-HRTimelineGroup
Lido Advisors, LLCin group Lido Advisors, LLC34,952$107K<0.01%013F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…19,553$99.7K<0.01%+2,34813F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP19,693$98.9K<0.01%+2813F-HR/ATimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC19,318$97K<0.01%013F-HRTimelineGroup
Caitong International Asset Management …19,197$96.4K0.02%new13F-HR/ATimeline
CANADA PENSION PLAN INVESTMENT BOARD17,600$88.4K<0.01%new13F-HRTimeline
Scientech Research LLC17,216$86.4K0.05%new13F-HRTimeline
Coastal Bridge Advisors, LLC17,000$85.3K0.01%013F-HRTimeline
Balefire, LLC15,000$75.3K0.01%013F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC14,801$74.3K<0.01%new13F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC14,757$74.1K<0.01%+3,73613F-HRTimeline
GROUP ONE TRADING LLC14,184$71.2K<0.01%-21,38113F-HRTimeline
Forefront Analytics, LLC13,226$66.4K0.06%-13,80113F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC12,000$60.2K<0.01%new13F-HRTimeline
Cygnus Capital Advisors, LLC12,000$60K0.04%13F-HRTimeline
Cambridge Investment Research Advisors,…10,700$54K<0.01%013F-HRTimeline
MOUNT VERNON ASSOCIATES INC /MD/10,500$53K0.04%new13F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV10,386$52.1K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC10,268$51.5K<0.01%new13F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…10,016$50.3K<0.01%new13F-HRTimelineGroup
Harbor Advisors LLC10,000$50.2K0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…9,689$48.6K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc9,307$46.7K<0.01%+83113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…6,163$30.9K<0.01%+16813F-HRTimeline
Geneos Wealth Management Inc.6,000$30.1K<0.01%013F-HRTimeline
Sterling Capital Management LLC5,967$30K<0.01%-64013F-HRTimeline
AMALGAMATED BANK3,144$16K<0.01%-22613F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,855$15K<0.01%-282,99313F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,987$15K<0.01%new13F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.2,843$14.3K<0.01%+47913F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,613$13.1K<0.01%013F-HRTimeline
Larson Financial Group LLC2,000$10K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,966$9.87K<0.01%-4,13013F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,132$5.68K<0.01%+913F-HRTimelineGroup
Essential Partners LLC1,087$5.46K<0.01%+79413F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.753$3.78K<0.01%new13F-HRTimelineGroup
IFP Advisors, Inc547$2.75K<0.01%+19713F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…539$2.71K<0.01%+24313F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.530$2.66K<0.01%-77413F-HRTimelineGroup
Allworth Financial LP416$2.09K<0.01%+26413F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.352$2K<0.01%013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…334$1.68K<0.01%new13F-HR/ATimelineGroup
ASSETMARK, INCin group ASSETMARK, INC333$1.67K<0.01%new13F-HRTimelineGroup
Farther Finance Advisors, LLC309$1.55K<0.01%+30813F-HRTimeline
HighMark Wealth Management LLC300$1.51K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.269$1.35K<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC236$1.19K<0.01%+7113F-HRTimeline
True Wealth Design, LLC211$1.06K<0.01%+15613F-HRTimeline
Sunbelt Securities, Inc.110$552<0.01%+2313F-HRTimeline
MAI Capital Management63$317<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.25$126<0.01%-113F-HRTimeline
Arax Advisory Partners19$95<0.01%-6,51113F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…4$20<0.01%new13F-HR/ATimelineGroup