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Disclosery

ANNX ANNEXON INC

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COM (common), issuer CIK 1528115

140 managers (144 13F filers) reported a position in ANNX shares at 2025-09-30, 101,381,026 shares in all. 32 filers opened a position and 17 filers sold out during the quarter.

Managers
140
13F filers
144
New
32
Added
51
Reduced
36
Sold out
17
Shares held by filers
101,381,026

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC11,081,163$33.8M<0.01%-4,614,06313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.7,899,008$24.1M<0.01%-63,36013F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL7,000,000$21.4M0.87%013F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC6,300,644$19.2M1.87%013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding5,848,356$17.8M+470,033Timeline
Bain Capital Life Sciences Investors, L…in group Bain Capital Life Sciences In…5,249,069$16M1.06%013F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG5,157,290$15.7M0.33%013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY3,029,848$9.24M<0.01%+2,197,30813F-HR/ATimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC2,822,823$8.61M0.01%+308,68913F-HRTimelineGroup
Woodline Partners LP2,638,275$8.05M0.04%+1,584,56613F-HRTimeline
Opaleye Management Inc.2,600,000$7.93M1.12%new13F-HRTimeline
Candriam S.C.A.2,534,230$7.73M0.04%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,436,944$7.43M<0.01%+152,17113F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,406,432$7.34M<0.01%+775,78313F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC2,192,354$6.69M<0.01%+26,17613F-HRTimelineGroup
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd2,112,455$6.44M0.94%-697,54513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP2,050,308$6.25M<0.01%+69,32413F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.1,794,387$5.47M1.3%+30,00013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,504,349$4.59M<0.01%+992,90113F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…1,500,000$4.58M0.01%new13F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management1,297,260$3.96M0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,294,302$3.95M<0.01%-158,49313F-HR/ATimelineGroup
J. Goldman & Co LP1,107,001$3.38M0.13%new13F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…1,066,932$3.25M0.03%-12,02913F-HRTimelineGroup
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…980,285$2.99M<0.01%-7,22813F-HRTimelineGroup
SIRIOS CAPITAL MANAGEMENT L P970,200$2.96M0.39%-19,37713F-HRTimeline
Rhenman & Partners Asset Management AB823,000$2.51M0.28%+363,00013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co790,250$2.41M<0.01%+61,86113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP787,708$2.4M<0.01%+44,48413F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP766,955$2.34M<0.01%-122,90813F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC753,579$2.3M<0.01%-24,32113F-HRTimeline
Nuveen, LLCin group TIAA682,558$2.08M<0.01%+426,64013F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC640,460$1.95M0.04%-215,11313F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…583,913$1.78M0.03%013F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC574,123$1.75M<0.01%+242,09213F-HRTimelineGroup
Qube Research & Technologies Ltd572,644$1.75M<0.01%+147,92413F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC532,363$1.62M<0.01%+63,15413F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding504,994$1.54M+30,467Timeline
PRICE T ROWE ASSOCIATES INC /MD/484,775$1.48M<0.01%-23,32813F-HRTimeline
Board of Trustees of The Leland Stanfor…482,550$1.47M0.17%013F-HRTimeline
Hennion & Walsh Asset Management, Inc.475,929$1.45M0.05%-8,70413F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN409,477$1.25M<0.01%+32,50313F-HRTimelineGroup
Parkman Healthcare Partners LLC405,953$1.24M0.14%+1,75913F-HRTimeline
UBS Group AGgroup of 2 filers holding346,139$1.06M-72,483Timeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp308,188$940K<0.01%+7,14013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding302,934$924K+101,774Timeline
Point72 Europe (London) LLP302,861$924K0.05%+96,06313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA285,848$871K<0.01%+40,64913F-HRTimelineGroup
ExodusPoint Capital Management, LP243,755$743K0.01%+182,06413F-HRTimeline
SummitTX Capital, L.P.241,991$738K0.03%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC236,736$722K<0.01%+25,54113F-HRTimelineGroup
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG223,221$681K0.01%-158,22013F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC219,494$669K<0.01%+73,62513F-HRTimelineGroup
Schonfeld Strategic Advisors LLC212,219$647K<0.01%-53,83113F-HRTimeline
Invesco Ltd.in group Invesco Ltd.201,945$616K<0.01%+51,53113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC167,500$511K<0.01%+154,23313F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.147,375$459K<0.01%+67,00013F-HRTimelineGroup
IEQ CAPITAL, LLC150,322$458K<0.01%+14,52513F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC147,930$451K<0.01%-29,69813F-HR/ATimelineGroup
XTX Topco Ltdin group XTX Topco Ltd147,840$451K0.02%new13F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.140,740$429K<0.01%013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC137,800$420K0.01%+40,00013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …132,673$405K<0.01%-1,36213F-HRTimelineGroup
RHUMBLINE ADVISERS132,603$404K<0.01%-4,93313F-HRTimeline
PARK AVENUE SECURITIES LLCin group PARK AVENUE SECURITIES LLC113,068$345K<0.01%013F-HRTimelineGroup
Quarry LP110,000$336K0.08%+66,86713F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…94,554$288K<0.01%+41,27113F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.90,049$275K<0.01%new13F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS84,523$258K<0.01%-15,05113F-HRTimelineGroup
HRT FINANCIAL LP84,582$257K<0.01%new13F-HRTimeline
Cinctive Capital Management LP65,466$200K0.01%-70,00013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding49,227$150K-7,416Timeline
ALPS ADVISORS INCin group ALPS ADVISORS INC47,879$146K<0.01%-11,32213F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO46,886$143K<0.01%-5,93313F-HR/ATimelineGroup
TD Asset Management Inc46,848$143K<0.01%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…44,632$136K<0.01%-14,39013F-HRTimelineGroup
Allegheny Financial Group42,900$131K0.02%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…41,987$128K0.04%+7,28913F-HRTimelineGroup
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…40,000$122K<0.01%+5,00013F-HRTimelineGroup
GROUP ONE TRADING LLC35,565$108K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…35,261$108K0.01%+13,22513F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC34,952$107K<0.01%-4813F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND34,479$105K<0.01%013F-HRTimeline
COMERICA BANK32,357$98.7K<0.01%+6,75013F-HRTimeline
Atom Investors LP30,453$92.9K0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…28,105$85.7K<0.01%+7,51813F-HRTimeline
AXQ CAPITAL, LP27,867$85K0.03%new13F-HRTimeline
Forefront Analytics, LLC27,027$82.4K0.08%-54813F-HRTimeline
Forefront Wealth Partners, LLC27,027$82.4K0.02%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC26,676$81.4K<0.01%-26,02313F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC25,721$78.1K<0.01%-4,13413F-HRTimelineGroup
CWM, LLCin group CWM, LLC23,488$72K<0.01%+5,75413F-HRTimelineGroup
Cubist Systematic Strategies, LLC22,771$69.5K<0.01%new13F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC22,589$68.9K<0.01%new13F-HRTimeline
MATAURO, LLC20,572$62.7K0.01%+9,48813F-HRTimeline
ProShare Advisors LLC20,288$61.9K<0.01%-3,44413F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC20,000$61K<0.01%new13F-HRTimelineGroup
EntryPoint Capital, LLC19,971$60.9K0.02%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS19,739$60.2K<0.01%+9,76013F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP19,665$60K<0.01%new13F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC19,318$58.9K<0.01%-8,13713F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…18,220$55.6K<0.01%new13F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…17,205$52.8K<0.01%new13F-HRTimeline
Coastal Bridge Advisors, LLC17,000$51.9K<0.01%013F-HRTimeline
Creative Planningin group Creative Planning15,451$47.1K<0.01%new13F-HRTimelineGroup
Balefire, LLC15,000$45.8K0.01%new13F-HRTimeline
49 WEALTH MANAGEMENT, LLC12,083$36.9K<0.01%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC11,670$35.6K<0.01%013F-HRTimelineGroup
SG Americas Securities, LLC10,997$34K<0.01%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC11,021$33.6K<0.01%-37013F-HRTimeline
Cambridge Investment Research Advisors,…10,700$33K<0.01%013F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.10,208$31.1K<0.01%13F-HR/ATimelineGroup
Harbor Advisors LLC10,000$30.5K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…9,689$29.6K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc8,476$25.9K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC6,828$20.8K<0.01%-30,96813F-HRTimelineGroup
Sterling Capital Management LLC6,607$20.2K<0.01%+3,84913F-HRTimeline
Arax Advisory Partners6,530$19.9K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,096$18.6K<0.01%-9,46213F-HRTimelineGroup
Geneos Wealth Management Inc.6,000$18.3K<0.01%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…5,995$18.3K<0.01%new13F-HRTimeline
AMALGAMATED BANK3,370$10K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,613$7.97K<0.01%-9413F-HRTimeline
GF FUND MANAGEMENT CO. LTD.2,364$7.21K<0.01%-36513F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.1,304$3.98K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,123$3.42K<0.01%+8913F-HRTimelineGroup
Clearstead Advisors, LLC355$1.08K<0.01%new13F-HRTimeline
IFP Advisors, Inc350$1.07K<0.01%+24213F-HR/ATimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.352$1K<0.01%013F-HRTimelineGroup
HighMark Wealth Management LLC300$915<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…296$903<0.01%+4413F-HRTimelineGroup
Essential Partners LLC293$894<0.01%+9113F-HRTimeline
Physician Wealth Advisors, Inc.269$821<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC165$503<0.01%013F-HRTimeline
Allworth Financial LP152$464<0.01%+10713F-HRTimeline
Sunbelt Securities, Inc.87$265<0.01%new13F-HRTimeline
True Wealth Design, LLC55$168<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.26$79<0.01%-413F-HRTimeline
Advisory Services Network, LLC23$70<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC1$3<0.01%013F-HRTimeline