DIADEMA PARTNERS LP
Follow13F filer, CIK 2026172, MORRISTOWN, NJ
DIADEMA PARTNERS LP reported $390,971,772 across 130 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 56.26% of the portfolio.
Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001892688-25-000193
- Period
- 2025-09-30
- Reported value
- $391M
- Holdings
- 130
- Top 10 weight
- 56.26%
- New
- 75
- Sold out
- 40
Largest buys vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| REGNadded | +24,553 | $13.8M |
| INDIVIOR PLCnew | +254,252 | $6.13M |
| BMYnew | +130,000 | $5.86M |
| ASNDnew | +27,572 | $5.48M |
| ALNYnew | +10,000 | $4.56M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Largest sells vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| AMGNexited | -52,100 | -$14.5M |
| LLYexited | -14,816 | -$11.5M |
| TGTXreduced | -310,700 | -$11.2M |
| JAZZreduced | -81,333 | -$10.7M |
| NBIXreduced | -56,288 | -$7.9M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Holdings, Q3 2025
Share positions as resolved from 13F-HR 0001892688-25-000193, largest first. % of portfolio is the value over $143,559,417, the sum of the share positions whose value is usable for ratios (method).
| Security | History | Shares | Value | % of portfolio | Change | Latest event | Timeline |
|---|---|---|---|---|---|---|---|
| REGNREGENERON PHARMACEUTICALS | 30,160 | $17M | 11.81% | +24,553 | Timeline | ||
| SLNOSOLENO THERAPEUTICS INC | 177,330 | $12M | 8.35% | -106,822 | Timeline | ||
| BMRNBIOMARIN PHARMACEUTICAL INC | 212,877 | $11.5M | 8.03% | +20,000 | Timeline | ||
| PCVXVAXCYTE INC | 218,285 | $7.86M | 5.48% | +20,000 | Timeline | ||
| INDIVIOR PLCINDIVIOR PLC | 254,252 | $6.13M | 4.27% | new | |||
| BMYBRISTOL-MYERS SQUIBB CO | 130,000 | $5.86M | 4.08% | new | Timeline | ||
| ASNDASCENDIS PHARMA A/S | 27,572 | $5.48M | 3.82% | new | Timeline | ||
| NBIXNEUROCRINE BIOSCIENCES INC | 37,754 | $5.3M | 3.69% | -56,288 | Timeline | ||
| VKTXVIKING THERAPEUTICS INC | 193,689 | $5.09M | 3.55% | -3,779 | Timeline | ||
| ALNYALNYLAM PHARMACEUTICALS INC | 10,000 | $4.56M | 3.18% | new | Timeline | ||
| IMCRIMMUNOCORE HLDGS PLC | 124,384 | $4.52M | 3.15% | +20,000 | Timeline | ||
| NKTRNEKTAR THERAPEUTICS | 75,000 | $4.27M | 2.97% | new | Timeline | ||
| ABVXABIVAX SA | 41,620 | $3.51M | 2.45% | new | Timeline | ||
| PTGXPROTAGONIST THERAPEUTICS INC | 51,185 | $3.4M | 2.37% | -25,000 | Timeline | ||
| JAZZJAZZ PHARMACEUTICALS PLC | 23,140 | $3.05M | 2.12% | -81,333 | Timeline | ||
| ANIPANI PHARMACEUTICALS INC | 31,400 | $2.88M | 2% | new | Timeline | ||
| RVMDREVOLUTION MEDICINES INC | 59,079 | $2.76M | 1.92% | -20,000 | Timeline | ||
| APGEAPOGEE THERAPEUTICS INC | 64,250 | $2.55M | 1.78% | +53,678 | Timeline | ||
| TERNTERNS PHARMACEUTICALS INC | 323,159 | $2.43M | 1.69% | +63,307 | Timeline | ||
| ARDXARDELYX INC | 400,000 | $2.2M | 1.54% | new | Timeline | ||
| TGTXTG THERAPEUTICS INC | 60,748 | $2.19M | 1.53% | -310,700 | Timeline | ||
| ALKSALKERMES PLC | 72,079 | $2.16M | 1.51% | new | Timeline | ||
| ROIVROIVANT SCIENCES LTD | 120,000 | $1.82M | 1.26% | new | Timeline | ||
| URGNUROGEN PHARMA LTD | 90,000 | $1.8M | 1.25% | -60,000 | Timeline | ||
| PCRXPACIRA BIOSCIENCES INC | 58,926 | $1.52M | 1.06% | 0 | Timeline | ||
| COGTCOGENT BIOSCIENCES INC | 97,813 | $1.4M | 0.98% | -294,400 | Timeline | ||
| NVONOVO-NORDISK A S | 25,000 | $1.39M | 0.97% | new | Timeline | ||
| HRMYHARMONY BIOSCIENCES HLDGS IN | 50,000 | $1.38M | 0.96% | new | Timeline | ||
| AMLXAMYLYX PHARMACEUTICALS INC | 100,000 | $1.36M | 0.95% | new | Timeline | ||
| RNAMAVIDITY BIOSCIENCES INC | 30,000 | $1.31M | 0.91% | new | Timeline | ||
| MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INC | 105,891 | $1.25M | 0.87% | -52,645 | |||
| VTGNVISTAGEN THERAPEUTICS INC | 349,789 | $1.24M | 0.86% | -54,133 | Timeline | ||
| MNKDMANNKIND CORP | 212,475 | $1.14M | 0.79% | new | Timeline | ||
| SUPNSUPERNUS PHARMACEUTICALS | 22,348 | $1.07M | 0.74% | new | Timeline | ||
| CPRXCATALYST PHARMACEUTICALS INC | 50,000 | $985K | 0.69% | new | Timeline | ||
| Reviva Pharmaceuticals Hold…Reviva Pharmaceuticals Holdings I… | 2,506,921 | $924K | 0.64% | -228,536 | |||
| ARCTARCTURUS THERAPEUTICS HLDGS | 48,811 | $900K | 0.63% | new | Timeline | ||
| TRVITREVI THERAPEUTICS INC | 85,830 | $785K | 0.55% | -100,000 | Timeline | ||
| XERSXERIS BIOPHARMA HOLDINGS INC | 74,753 | $608K | 0.42% | new | Timeline | ||
| CTMXCYTOMX THERAPEUTICS INC. | 185,286 | $591K | 0.41% | new | Timeline | ||
| MRNAMODERNA INC | 20,000 | $517K | 0.36% | new | Timeline | ||
| AYTUAYTU BIOPHARMA INC | 272,670 | $513K | 0.36% | new | Timeline | ||
| TNYATENAYA THERAPEUTICS INC | 315,519 | $511K | 0.36% | new | Timeline | ||
| EQEQUILLIUM INC | 300,000 | $429K | 0.3% | new | Timeline | ||
| ALECALECTOR INC | 136,023 | $403K | 0.28% | -130,000 | Timeline | ||
| PRQRPROQR THRAPEUTICS N V | 157,694 | $336K | 0.23% | 0 | Timeline | ||
| PYXSPYXIS ONCOLOGY INC | 150,000 | $333K | 0.23% | new | Timeline | ||
| PTHSPELTHOS THERAPEUTICS INC | 10,498 | $294K | 0.2% | new | Timeline | ||
| RAREULTRAGENYX PHARMACEUTICAL IN | 9,189 | $276K | 0.19% | -44,796 | Timeline | ||
| CLYMCLIMB BIO INC | 136,488 | $274K | 0.19% | -565,647 | Timeline | ||
| NEUPNEUPHORIA THERAPEUTICS INC | 21,452 | $253K | 0.18% | new | Timeline | ||
| FHTXFOGHORN THERAPEUTICS INC | 50,000 | $244K | 0.17% | new | Timeline | ||
| OVIDOVID THERAPEUTICS INC | 187,739 | $244K | 0.17% | new | Timeline | ||
| RLAYRELAY THERAPEUTICS INC | 43,616 | $228K | 0.16% | 0 | Timeline | ||
| VTYXVENTYX BIOSCIENCES INC | 71,204 | $221K | 0.15% | new | Timeline | ||
| PRTCYPURETECH HEALTH PLC | 7,324 | $135K | 0.09% | 0 | Timeline | ||
| ANABANAPTYSBIO INC | 3,295 | $101K | 0.07% | new | Timeline | ||
| TVRDTVARDI THERAPEUTICS INC | 2,185 | $85.1K | 0.06% | new | Timeline | ||
| PMVPPMV PHARMACEUTICALS INC | 11,300 | $15.8K | 0.01% | new | Timeline |
Options
Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).
| Security | Type | Amount | Value | Change |
|---|---|---|---|---|
| QUREUNIQURE NV SHS | put | 300,000 | $17.5M | new |
| SPYSTATE STR SPDR S&P 500 ETF T SHS | put | 20,000 | $13.3M | new |
| JAZZJAZZ PHARMACEUTICALS PLC Stock | call | 100,000 | $13.2M | +50,000 |
| VKTXVIKING THERAPEUTICS INC COM | call | 405,100 | $10.6M | new |
| AGIOAGIOS PHARMACEUTICALS INC COM | call | 222,100 | $8.92M | +100,000 |
| RNAMAVIDITY BIOSCIENCES INC Stock | call | 200,100 | $8.72M | new |
| INCYINCYTE CORP Stock | call | 100,000 | $8.48M | new |
| NTLAINTELLIA THERAPEUTICS INC COM | call | 470,200 | $8.12M | new |
| BMYBRISTOL-MYERS SQUIBB CO COM | call | 180,000 | $8.12M | new |
| LLYELI LILLY & CO COM | put | 10,000 | $7.63M | -10,700 |
| CRSPCRISPR THERAPEUTICS AG Stock | call | 112,000 | $7.26M | 0 |
| BBIOBRIDGEBIO PHARMA INC COM | call | 131,400 | $6.82M | 0 |
| SLNOSOLENO THERAPEUTICS INC COM | put | 100,000 | $6.76M | new |
| JAZZJAZZ PHARMACEUTICALS PLC Stock | put | 50,000 | $6.59M | new |
| IONSIONIS PHARMACEUTICALS INC Stock | call | 100,000 | $6.54M | new |
| MNKDMANNKIND CORP Stock | call | 1,039,500 | $5.58M | +519,600 |
| NVONOVO-NORDISK A S ADR | put | 100,000 | $5.55M | new |
| PRAXPRAXIS PRECISION MEDICINES I COM NEW | put | 100,000 | $5.3M | new |
| APGEAPOGEE THERAPEUTICS INC Stock | call | 127,400 | $5.06M | -28,900 |
| ROIVROIVANT SCIENCES LTD SHS | put | 300,000 | $4.54M | new |
| RAREULTRAGENYX PHARMACEUTICAL IN COM | call | 150,000 | $4.51M | -67,000 |
| HRMYHARMONY BIOSCIENCES HLDGS IN COM | call | 150,000 | $4.13M | new |
| UPBUPSTREAM BIO INC COMMON STOCK | call | 200,000 | $3.76M | new |
| SRRKSCHOLAR ROCK HLDG CORP COM | call | 100,000 | $3.72M | new |
| RAREULTRAGENYX PHARMACEUTICAL IN COM | put | 123,300 | $3.71M | 0 |
| RXRXRECURSION PHARMACEUTICALS IN CL A | call | 698,400 | $3.41M | 0 |
| SLNOSOLENO THERAPEUTICS INC COM | call | 50,000 | $3.38M | new |
| ZYMEZYMEWORKS INC COM | call | 196,500 | $3.36M | +17,200 |
| MREOMEREO BIOPHARMA GROUP PLC CMN | call | 1,520,200 | $3.13M | +202,600 |
| COGTCOGENT BIOSCIENCES INC COM | call | 200,000 | $2.87M | +193,100 |
| ARCTARCTURUS THERAPEUTICS HLDGS COM | put | 150,900 | $2.78M | new |
| MRNAMODERNA INC COM | call | 102,100 | $2.64M | 0 |
| SCPHARMACEUTICALS INCSCPHARMACEUTICALS INC COM | call | 462,000 | $2.62M | -24,500 |
| MRNAMODERNA INC COM | put | 100,000 | $2.58M | 0 |
| REPLREPLIMUNE GROUP INC COMMON STOCK | call | 612,300 | $2.57M | new |
| ABUSARBUTUS BIOPHARMA CORP Common Shares, without par value | call | 516,300 | $2.34M | new |
| CORTCORCEPT THERAPEUTICS INC COM | put | 26,500 | $2.2M | -73,700 |
| GOSSGOSSAMER BIO INC Stock | call | 824,800 | $2.17M | 0 |
| CAPRCAPRICOR THERAPEUTICS INC COMMON STOCK | call | 300,000 | $2.16M | new |
| ACADACADIA PHARMACEUTICALS INC COM | call | 89,000 | $1.9M | +100 |
| MBXMBX BIOSCIENCES INC Stock | call | 100,000 | $1.75M | new |
| ALTALTIMMUNE INC COM NEW | call | 463,000 | $1.75M | -799,900 |
| TERNTERNS PHARMACEUTICALS INC Stock | call | 225,200 | $1.69M | +64,300 |
| OCULOCULAR THERAPEUTIX INC COM | call | 136,700 | $1.6M | 0 |
| TECXTECTONIC THERAPEUTIC INC COMMON STOCK | call | 100,000 | $1.57M | new |
| SMMTSUMMIT THERAPEUTICS INC COM | call | 74,700 | $1.54M | 0 |
| NVAXNOVAVAX INC COM NEW | call | 173,500 | $1.5M | new |
| HRMYHARMONY BIOSCIENCES HLDGS IN COM | put | 50,100 | $1.38M | new |
| AVXLANAVEX LIFE SCIENCES CORP COM NEW | call | 139,800 | $1.24M | new |
| SKYESKYE BIOSCIENCE INC COM NEW | call | 300,000 | $1.18M | new |
| CRMDCORMEDIX INC Stock | put | 100,000 | $1.16M | new |
| EDITEDITAS MEDICINE INC COM | call | 300,000 | $1.04M | new |
| FOLDAMICUS THERAPEUTIC COM | call | 131,400 | $1.04M | 0 |
| OLMAOLEMA PHARMACEUTICALS INC COM | call | 90,500 | $886K | new |
| PBYIPUMA BIOTECHNOLOGY INC COMMON STOCK | call | 135,900 | $722K | new |
| SLSSELLAS LIFE SCIENCES GROUP I COM NEW | call | 400,000 | $644K | 0 |
| KODKODIAK SCIENCES INC COM | call | 27,800 | $455K | new |
| CRVSCORVUS PHARMACEUTICALS INC COM | put | 50,000 | $368K | new |
| VTGNVISTAGEN THERAPEUTICS INC COM | call | 100,200 | $356K | +100,000 |
| CCCCC4 THERAPEUTICS INC COM STK | call | 140,700 | $312K | new |
| MLTXMOONLAKE IMMUNOTHERAPEUTICS Stock | call | 26,100 | $187K | new |
| RCELAVITA MEDICAL INC COM | call | 25,100 | $128K | new |
| ATYRATYR PHARMA INC COM NEW | call | 128,700 | $92.8K | 0 |
| MREOMEREO BIOPHARMA GROUP PLC CMN | put | 39,400 | $81.2K | 0 |
| ATYRATYR PHARMA INC COM NEW | put | 76,200 | $55K | 0 |
| FLNAFILANA THERAPEUTICS INC CMN | put | 9,900 | $28.8K | new |
| KODKODIAK SCIENCES INC COM | put | 1,100 | $18K | new |
| Applied Therapeutics IncApplied Therapeutics Inc Common Stock | call | 19,000 | $11.5K | new |
| AUPHAURINIA PHARMACEUTICALS INC Stock | put | 700 | $7.74K | new |
| TVTXTRAVERE THERAPEUTICS INC COM | put | 300 | $7.17K | new |
| JBIOJADE BIOSCIENCES INC COM NEW | put | 1,046 | $2.77K | new |
Sold out in Q3 2025
Positions in the previous quarter's report that this quarter's report no longer lists.
| Security | Shares before | Value before | Type |
|---|---|---|---|
| AMGNAMGEN INC | 62,100 | $17.3M | put |
| AMGNAMGEN INC | 52,100 | $14.5M | shares |
| LLYELI LILLY & CO | 14,816 | $11.5M | shares |
| XBISPDR SERIES TRUST | 100,000 | $8.29M | call |
| LLYELI LILLY & CO | 10,000 | $7.8M | call |
| RVMDREVOLUTION MEDICINES INC | 200,000 | $7.36M | call |
| NVONOVO-NORDISK A S | 100,000 | $6.9M | call |
| SPRYARS PHARMACEUTICALS INC | 280,700 | $4.9M | call |
| PFEPFIZER INC | 200,000 | $4.85M | call |
| VRTXVERTEX PHARMACEUTICALS INC | 10,000 | $4.45M | shares |
| GILDGILEAD SCIENCES INC | 30,000 | $3.33M | shares |
| ARGXARGENX SE | 5,974 | $3.29M | shares |
| SRRKSCHOLAR ROCK HLDG CORP | 62,926 | $2.23M | shares |
| ITEOS THERAPEUTICS INCITEOS THERAPEUTICS INC | 206,200 | $2.06M | shares |
| MLTXMOONLAKE IMMUNOTHERAPEUTICS | 41,300 | $1.95M | put |
| VRDNVIRIDIAN THERAPEUTICS INC | 122,061 | $1.71M | shares |
| MRKMERCK & CO INC | 20,000 | $1.58M | shares |
| Reviva Pharmaceuticals Hold…Reviva Pharmaceuticals Holdings I… | 4,000,000 | $1.52M | call |
| QUREUNIQURE NV | 104,100 | $1.45M | call |
| COGTCOGENT BIOSCIENCES INC | 201,400 | $1.45M | put |
| BHVNBIOHAVEN LTD | 100,000 | $1.41M | call |
| OLMAOLEMA PHARMACEUTICALS INC | 253,657 | $1.08M | shares |
| SMMTSUMMIT THERAPEUTICS INC | 50,000 | $1.06M | put |
| CAPRCAPRICOR THERAPEUTICS INC | 106,600 | $1.06M | put |
| BMEABIOMEA FUSION INC | 568,900 | $1.02M | call |
| TNGXTANGO THERAPEUTICS INC | 200,000 | $1.02M | call |
| 89BIO INC89BIO INC | 98,382 | $966K | shares |
| SCPHARMACEUTICALS INCSCPHARMACEUTICALS INC | 217,623 | $829K | shares |
| ARVNARVINAS INC | 96,455 | $710K | shares |
| ALTALTIMMUNE INC | 171,400 | $663K | put |
| CRDFCARDIFF ONCOLOGY INC | 208,100 | $656K | call |
| PRTAPROTHENA CORP PLC | 100,000 | $607K | call |
| PHATPHATHOM PHARMACEUTICALS INC | 40,294 | $386K | shares |
| NUVLNUVALENT INC | 5,000 | $382K | shares |
| REPLREPLIMUNE GROUP INC | 32,483 | $302K | shares |
| ELDNELEDON PHARMACEUTICALS INC | 64,613 | $175K | shares |
| ELEVATION ONCOLOGY INC COMELEVATION ONCOLOGY INC COM | 362,935 | $133K | shares |
| NKTRNEKTAR THERAPEUTICS | 47,474 | $85.9K | call |
| SMMTSUMMIT THERAPEUTICS INC | 932 | $19.8K | shares |
| ZLABZAI LAB LTD | 3,785 | $13.2K | shares |
How Q3 2025 was built
Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).
| Filing | Role | Amendment | Filed | Accepted | Ingested |
|---|---|---|---|---|---|
| 13F-HR 0001892688-25-000193 | base | 2025-11-14 | acceptance time not in the bulk data set |