Affinity Asset Advisors, LLC

13F filer, CIK 1773195, NEW YORK, NY

Affinity Asset Advisors, LLC reported $732,761,256 across 86 holdings for the quarter ended 2024-09-30, in a 13F-HR filed 2024-11-13. Its ten largest share positions make up 44.28% of the portfolio.

Filed 2024-11-13 (acceptance time not in the bulk data set), ingested 2026-10-07 18:26:56 UTC13F-HR 0001839882-24-038904

Period: 2024-09-30
Reported value: $733M
Holdings: 86
Top 10 weight: 44.28%
New: 18
Sold out: 30

Largest buys vs the previous quarter

Security	Shares change	Approx. value
NUVLadded	+137,500	$14.1M
ALKSadded	+350,000	$9.8M
ORKAnew	+349,836	$8.57M
VRDNadded	+375,000	$8.53M
WVEadded	+1,025,000	$8.4M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

Security	Shares change	Approx. value
CEREVEL THERAPEUTICS HLDNG Iexited	-500,000	-$20.4M
ONCreduced	-75,000	-$16.8M
CLDXreduced	-350,400	-$11.9M
APGEreduced	-172,085	-$10.1M
MORPHIC HLDG INCexited	-250,573	-$8.54M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2024

Share positions as resolved from 13F-HR 0001839882-24-038904, largest first. % of portfolio is the value over $644,524,697, the sum of the share positions whose value is usable for ratios (method).

Security	Shares	Value	% of portfolio	Change	Timeline
XENEXENON PHARMACEUTICALS INC	1,144,021	$45M	6.99%	+149,794	Timeline
APGEAPOGEE THERAPEUTICS INC	664,198	$39M	6.05%	-172,085	Timeline
NUVLNUVALENT INC	337,500	$34.5M	5.36%	+137,500	Timeline
ACLXARCELLX INC	400,000	$33.4M	5.18%	-60,000	Timeline
ALKSALKERMES PLC	1,000,000	$28M	4.34%	+350,000	Timeline
TEVATEVA PHARMACEUTICAL INDS LTD	1,400,000	$25.2M	3.91%	-50,000	Timeline
MDGLMADRIGAL PHARMACEUTICALS INC	100,000	$21.2M	3.29%	-10,000	Timeline
CRNXCRINETICS PHARMACEUTICALS IN	400,000	$20.4M	3.17%	-115,000	Timeline
NRIXNURIX THERAPEUTICS INC	860,399	$19.3M	3%	-51,601	Timeline
VERAVERA THERAPEUTICS INC	435,000	$19.2M	2.98%	+60,000	Timeline
VERONA PHARMA PLCVERONA PHARMA PLC	650,000	$18.7M	2.9%	-50,000
AUTLAUTOLUS THERAPEUTICS LTD	4,500,000	$16.3M	2.53%	+200,000	Timeline
CNTACENTESSA PHARMACEUTICALS PLC	965,612	$15.4M	2.4%	-170,090	Timeline
INOZYME PHARMA INCINOZYME PHARMA INC	2,822,318	$14.8M	2.29%	-33,934
SYRESPYRE THERAPEUTICS INC	498,420	$14.7M	2.27%	-15,000	Timeline
KURAKURA ONCOLOGY INC	687,785	$13.4M	2.09%	+37,785	Timeline
ESTAESTABLISHMENT LABS HLDGS INC	290,447	$12.6M	1.95%	+67,040	Timeline
VRDNVIRIDIAN THERAPEUTICS INC	525,000	$11.9M	1.85%	+375,000	Timeline
WVEWAVE LIFE SCIENCES LTD	1,400,000	$11.5M	1.78%	+1,025,000	Timeline
ORKAORUKA THERAPEUTICS INC	349,836	$8.57M	1.33%	new	Timeline
RZLTREZOLUTE INC	1,700,000	$8.24M	1.28%	-150,000	Timeline
MERUS N VMERUS N V	161,741	$8.08M	1.25%	+36,741
ASTRIA THERAPEUTICS INCASTRIA THERAPEUTICS INC	725,106	$7.98M	1.24%	-250,500
ONCBEONE MEDICINES LTD	35,000	$7.86M	1.22%	-75,000	Timeline
NAMSNEWAMSTERDAM PHARMA COMPANY	472,390	$7.84M	1.22%	+49,235	Timeline
BBIOBRIDGEBIO PHARMA INC	300,000	$7.64M	1.19%	+200,000	Timeline
CLYMCLIMB BIO INC	1,500,000	$7.63M	1.18%	-170,661	Timeline
AXSMAXSOME THERAPEUTICS INC.	80,000	$7.19M	1.12%	0	Timeline
ERASERASCA INC	2,499,431	$6.82M	1.06%	0	Timeline
GERNGERON CORP	1,500,000	$6.81M	1.06%	0	Timeline
CATXPERSPECTIVE THERAPEUTICS INC	500,000	$6.67M	1.04%	-50,000	Timeline
IMVTIMMUNOVANT INC	225,000	$6.41M	1%	-121,088	Timeline
ARWRARROWHEAD PHARMACEUTICALS IN	325,000	$6.3M	0.98%	+275,000	Timeline
PCVXVAXCYTE INC	50,000	$5.71M	0.89%	-10,000	Timeline
ARVNARVINAS INC	225,000	$5.54M	0.86%	new	Timeline
TERNTERNS PHARMACEUTICALS INC	600,000	$5M	0.78%	new	Timeline
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INC	147,500	$4.73M	0.73%	+77,501
CGEMCULLINAN THERAPEUTICS INC	263,817	$4.42M	0.69%	0	Timeline
CLDXCELLDEX THERAPEUTICS INC NEW	125,000	$4.25M	0.66%	-350,400	Timeline
MLYSMINERALYS THERAPEUTICS INC	350,000	$4.24M	0.66%	+22,041	Timeline
INSMINSMED INC	50,000	$3.65M	0.57%	-75,000	Timeline
FRNMPERCEPTIVE CAP SOLUTIONS COR	350,000	$3.51M	0.54%	0	Timeline
NEXTCURE INCNEXTCURE INC	2,302,598	$3.15M	0.49%	+614,643
SVRASAVARA INC	700,000	$2.97M	0.46%	-846,850	Timeline
NKTXNKARTA INC	650,000	$2.94M	0.46%	+450,000	Timeline
MIRMMIRUM PHARMACEUTICALS INC	75,000	$2.92M	0.45%	-80,000	Timeline
IMTXIMMATICS N.V	250,000	$2.85M	0.44%	-50,000	Timeline
HELIX ACQUISITION CORP IIHELIX ACQUISITION CORP II	250,000	$2.61M	0.41%	0
CNTXCONTEXT THERAPEUTICS INC	1,321,153	$2.59M	0.4%	-297,987	Timeline
INARI MED INCINARI MED INC	60,000	$2.47M	0.38%	-140,000
ROIVROIVANT SCIENCES LTD	201,587	$2.33M	0.36%	-150,000	Timeline
KEZAR LIFE SCIENCES INCKEZAR LIFE SCIENCES INC	2,511,778	$1.94M	0.3%	+750,000
CMPSCOMPASS PATHWAYS PLC	300,512	$1.89M	0.29%	-200,000	Timeline
TECXTECTONIC THERAPEUTIC INC	58,331	$1.77M	0.27%	0	Timeline
NEWAMSTERDAM PHARMA COMPANYNEWAMSTERDAM PHARMA COMPANY	212,974	$1.49M	0.23%	+10,375
SLNOSOLENO THERAPEUTICS INC	25,000	$1.26M	0.2%	new	Timeline
AEROVATE THERAPEUTICS INCAEROVATE THERAPEUTICS INC	600,000	$1.25M	0.19%	+400,000
QTTBQ32 BIO INC	27,777	$1.24M	0.19%	0	Timeline
VSTMVERASTEM INC	400,000	$1.2M	0.19%	new	Timeline
BMRNBIOMARIN PHARMACEUTICAL INC	15,000	$1.05M	0.16%	new	Timeline
ZURAZURA BIO LTD	223,335	$907K	0.14%	0	Timeline
PBYIPUMA BIOTECHNOLOGY INC	250,000	$638K	0.1%	0	Timeline
REPARE THERAPEUTICS INCREPARE THERAPEUTICS INC	173,351	$596K	0.09%	new
KYTXKYVERNA THERAPEUTICS INC	119,900	$586K	0.09%	-80,100	Timeline
ADGMADAGIO MED HLDGS INC	213,235	$550K	0.09%	new	Timeline
IMMATICS N.VIMMATICS N.V	187,204	$431K	0.07%	0
AVTXAVALO THERAPEUTICS INC	45,000	$426K	0.07%	0	Timeline
VYGRVOYAGER THERAPEUTICS INC	51,727	$303K	0.05%	new	Timeline
METAVIA INCMETAVIA INC	89,222	$283K	0.04%	0
GNLXGENELUX CORPORATION	100,000	$237K	0.04%	0	Timeline
WHWKWHITEHAWK THERAPEUTICS INC	47,019	$96.9K	0.02%	new	Timeline
PROMIS NEUROSCIENCES INCPROMIS NEUROSCIENCES INC	30,643	$38.3K	0.01%	-235,315
RCKTWROCKET PHARMACEUTICALS INC	75,000	$5.25K	<0.01%	0	Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

Security	Type	Amount	Value	Change
FLNAFILANA THERAPEUTICS INC CMN	put	1,449,300	$42.7M	new
TEVATEVA PHARMACEUTICAL INDS LTD ADR	call	1,000,000	$18M	-150,000
ANABANAPTYSBIO INC COM	put	200,000	$6.7M	new
SPRYARS PHARMACEUTICALS INC COM	call	400,000	$5.8M	new
NVAXNOVAVAX INC COM NEW	call	300,000	$3.79M	new
GALTGALECTIN THERAPEUTICS INC COMMON STOCK	put	1,211,400	$3.33M	new
SMMTSUMMIT THERAPEUTICS INC COM	call	140,000	$3.07M	new
SYRSSYROS PHARMACEUTICALS INC COM COM NEW	put	1,234,200	$2.65M	new
IMVTIMMUNOVANT INC COM	call	78,000	$2.22M	+23,700

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

Security	Type	Amount	Value	Change
OMEROS CORPOMEROS CORP NOTE 5.250% 2/1	principal	21,525,000	$14.6M	+10,075,000
COHERUS ONCOLOGY INCCOHERUS ONCOLOGY INC BOND	principal	16,625,000	$13.1M	+4,875,000
KARYOPHARM THERAPEUTICS INCKARYOPHARM THERAPEUTICS INC BOND	principal	12,250,000	$9.62M	+2,500,000
TRAVERE THERAPEUTICS INCTRAVERE THERAPEUTICS INC CNV	principal	5,000,000	$4.32M	new

Sold out in Q3 2024

Positions in the previous quarter's report that this quarter's report no longer lists.

Security	Shares before	Value before	Type
SPYSTATE STR SPDR S&P 500 ETF T	350,000	$190M	put
CEREVEL THERAPEUTICS HLDNG ICEREVEL THERAPEUTICS HLDNG I	500,000	$20.4M	shares
BRIDGEBIO PHARMA INCBRIDGEBIO PHARMA INC	17,000,000	$17.3M	principal
ALNYLAM PHARMACEUTICALS INCALNYLAM PHARMACEUTICALS INC	15,000,000	$16.2M	principal
CEREVEL THERAPEUTICS HLDNG ICEREVEL THERAPEUTICS HLDNG I	250,000	$10.2M	call
MORPHIC HLDG INCMORPHIC HLDG INC	250,573	$8.54M	shares
ELEVATION ONCOLOGY INC COMELEVATION ONCOLOGY INC COM	1,468,825	$3.97M	shares
HILLEVAX INCHILLEVAX INC	265,859	$3.84M	shares
DYNDYNE THERAPEUTICS INC	100,000	$3.53M	shares
XBISPDR SERIES TRUST	37,550	$3.48M	shares
BDTXBLACK DIAMOND THERAPEUTICS I	650,000	$3.03M	shares
OLMAOLEMA PHARMACEUTICALS INC	275,000	$2.98M	shares
SANASANA BIOTECHNOLOGY INC	521,000	$2.84M	put
TWSTTWIST BIOSCIENCE CORP	45,000	$2.22M	call
VIRVIR BIOTECHNOLOGY INC	200,000	$1.78M	shares
RAPT THERAPEUTICS INCRAPT THERAPEUTICS INC	545,000	$1.66M	put
ZYMEZYMEWORKS INC	191,127	$1.63M	shares
FULCFULCRUM THERAPEUTICS INC	250,000	$1.55M	call
Mersana Therapeutics IncMersana Therapeutics Inc	767,000	$1.54M	shares
ARYA SCIENCES ACQU CORP IVARYA SCIENCES ACQU CORP IV	133,500	$1.53M	shares
ADCTADC THERAPEUTICS SA	474,744	$1.5M	shares
TNGXTANGO THERAPEUTICS INC	150,274	$1.29M	shares
IOVAIOVANCE BIOTHERAPEUTICS INC	150,000	$1.2M	put
PCVXVAXCYTE INC	15,000	$1.13M	call
ALXOALX ONCOLOGY HLDGS INC	100,000	$603K	call
INSMINSMED INC	8,700	$583K	put
ORUKA THERAPEUTICS INC COMORUKA THERAPEUTICS INC COM	72,484	$278K	shares
RAPT THERAPEUTICS INCRAPT THERAPEUTICS INC	75,000	$229K	shares
PASSAGE BIO INCPASSAGE BIO INC	264,266	$210K	shares
IOVAIOVANCE BIOTHERAPEUTICS INC	100	$802	shares

How Q3 2024 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

Filing	Role	Amendment	Filed	Accepted	Ingested
13F-HR 0001839882-24-038904	base		2024-11-13	acceptance time not in the bulk data set	2026-10-07 18:26:56 UTC