SR One Capital Management, LP More: the full row for SR One Capital Management, LP 4,911,539 $38.8M 9.97% 0 13F-HR Timeline ENAVATE SCIENCES GP, LLC More: the full row for ENAVATE SCIENCES GP, LLC 3,761,359 $29.7M 22.39% 0 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 2,852,371 $22.5M <0.01% +1,070,656 13F-HR Timeline Group NEA Management Company, LLC More: the full row for NEA Management Company, LLC 2,613,948 $20.7M 1.59% 0 13F-HR Timeline NOVO HOLDINGS A/S More: the full row for NOVO HOLDINGS A/S 2,214,967 $17.5M 1.33% +614,967 13F-HR Timeline Fairmount Funds Management LLC in group Fairmount Funds Management LLC More: the full row for Fairmount Funds Management LLC 1,892,806 $15M 2.32% 0 13F-HR Timeline Group NVP ASSOCIATES, LLC More: the full row for NVP ASSOCIATES, LLC 1,838,482 $14.5M 12.95% 0 13F-HR Timeline DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 1,562,942 $12.3M 0.24% 0 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 1,183,260 $9.35M 1.24% 0 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 1,158,000 $9.15M 0.02% 0 13F-HR Timeline Group ArrowMark Colorado Holdings LLC More: the full row for ArrowMark Colorado Holdings LLC 1,097,369 $8.67M 0.14% +469,700 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 1,014,110 $8.01M <0.01% +7,552 13F-HR Timeline Group VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 975,906 $7.71M <0.01% -3,417 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 878,667 $6.94M 0.4% 0 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 873,623 $6.9M <0.01% -261,666 13F-HR Timeline Group Pivotal bioVenture Partners Investment … in group Pivotal bioVenture Partners I… More: the full row for Pivotal bioVenture Partners Investment Advisor LLC 736,645 $5.82M 4.71% 0 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 517,606 $4.09M <0.01% +6,386 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 445,588 $3.52M 0.4% +273,485 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 357,156 $2.82M <0.01% +8,396 13F-HR Timeline Group Catalio Capital Management, LP in group Catalio Capital Management, LP More: the full row for Catalio Capital Management, LP 295,148 $2.33M 0.58% +107,964 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 266,200 $2.1M <0.01% +54,694 13F-HR Timeline Group SCHRODER INVESTMENT MANAGEMENT GROUP More: the full row for SCHRODER INVESTMENT MANAGEMENT GROUP 164,035 $1.34M <0.01% -7,905 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 120,238 $950K <0.01% -4,008 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 116,140 $918K <0.01% -2,520 13F-HR/A Timeline Group SUPERSTRING CAPITAL MANAGEMENT LP More: the full row for SUPERSTRING CAPITAL MANAGEMENT LP 111,605 $882K 1.05% 0 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 77,910 $615K <0.01% -280,302 13F-HR Timeline Group Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 44,067 $348K 0.01% new 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 35,188 $278K <0.01% -756 13F-HR Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 31,757 $251K 0.02% -24,282 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 31,626 $250K <0.01% 13F-HR Timeline Group ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 28,132 $222K <0.01% -5,658 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 25,298 $200K <0.01% +7,053 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 23,957 $189K <0.01% -18,217 13F-HR/A Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 22,990 $182K <0.01% 0 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 20,765 $164K <0.01% -110,900 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 18,637 $147K <0.01% new 13F-HR Timeline Group Birchview Capital, LP More: the full row for Birchview Capital, LP 16,500 $130K 0.11% 0 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 16,160 $128K <0.01% -7,779 13F-HR/A Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 11,956 $94.5K <0.01% new 13F-HR/A Timeline Group INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 11,599 $91.6K <0.01% new 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 11,514 $91K <0.01% -27,428 13F-HR/A Timeline STONERIDGE INVESTMENT PARTNERS LLC More: the full row for STONERIDGE INVESTMENT PARTNERS LLC 10,955 $87K 0.07% 0 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 10,810 $85.4K <0.01% -1,294 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 10,579 $83.6K <0.01% -10,996 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 10,087 $79.7K <0.01% -138 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 8,986 $71K <0.01% +390 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 8,163 $64.5K <0.01% +181 13F-HR Timeline Group Corebridge Financial, Inc. in group Corebridge Financial, Inc. More: the full row for Corebridge Financial, Inc. 7,529 $59.5K <0.01% -111 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 7,267 $57.4K <0.01% -22,572 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 6,500 $51.4K <0.01% +83 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 6,200 $49K <0.01% new 13F-HR/A Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 4,499 $35.5K <0.01% 0 13F-HR Timeline STRS OHIO More: the full row for STRS OHIO 2,800 $22.1K <0.01% 0 13F-HR Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 1,608 $12.7K <0.01% 0 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 1,519 $12K <0.01% 0 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,411 $11.1K <0.01% +294 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1,144 $9.04K <0.01% 0 13F-HR Timeline AMALGAMATED BANK More: the full row for AMALGAMATED BANK 524 $4K <0.01% 0 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 476 $4K <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 454 $4K <0.01% -686 13F-HR/A Timeline Group US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 273 $2.16K <0.01% new 13F-HR Timeline Group Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 131 $1.03K <0.01% -95 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 128 $1.01K <0.01% new 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 41 $324 <0.01% new 13F-HR/A Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 28 $221 <0.01% new 13F-HR Timeline True Wealth Design, LLC More: the full row for True Wealth Design, LLC 3 $24 <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 2 $16 <0.01% new 13F-HR Timeline Group CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.