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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,489 managers (1,526 13F filers) reported a position in VRTX shares at 2025-09-30, 232,268,877 shares in all. 129 filers opened a position and 156 filers sold out during the quarter.

Managers
1,489
13F filers
1,526
New
129
Added
554
Reduced
616
Sold out
156
Shares held by filers
232,268,877

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
DAVIDSON INVESTMENT ADVISORS62,421$24.4M1.04%-1,26813F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A62,387$24.4M0.08%13F-HRTimelineGroup
Rakuten Group, Inc.group of 2 filers holding242,481$24.1M+242,463Timeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…61,569$24.1M0.12%-1,41213F-HRTimeline
FOSTER DYKEMA CABOT & PARTNERS, LLC60,689$23.8M1.56%-23413F-HRTimeline
SG Americas Securities, LLC60,062$23.5M0.09%-55,57813F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC58,285$22.8M0.03%-1,11313F-HRTimeline
ZACKS INVESTMENT MANAGEMENT58,026$22.7M0.18%+3,71013F-HRTimeline
MOODY LYNN LIEBERSON & WALKER, LLC56,559$22.2M1.19%-1,51813F-HRTimeline
AMALGAMATED BANK56,514$22.1M0.16%+77913F-HRTimeline
AIA Group Ltdin group AIA Group Ltd56,054$22M0.39%+11,57013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC55,778$21.8M0.08%-9,63913F-HRTimeline
Harvest Fund Management Co., Ltdin group Harvest Fund Management Co., …50,671$21.8M0.92%+1,15613F-HRTimelineGroup
Quantinno Capital Management LP55,641$21.8M0.06%+9,31913F-HRTimeline
Reynders McVeigh Capital Management, LLC55,350$21.7M1.02%+1,04013F-HRTimeline
ATWOOD & PALMER INC55,297$21.7M1.27%+10513F-HRTimeline
Edgemoor Investment Advisors, Inc.55,194$21.6M1.67%-83013F-HRTimeline
Hemenway Trust Co LLC55,125$21.6M1.65%-39013F-HRTimeline
Artia Global Partners LP55,100$21.6M3.8%+50,70013F-HR/ATimeline
FORSTA AP-FONDEN55,000$21.5M0.13%+3,00013F-HRTimeline
Sumitomo Mitsui DS Asset Management Com…in group SUMITOMO MITSUI FINANCIAL GRO…54,994$21.5M0.17%+6,90413F-HRTimelineGroup
Retirement Systems of Alabama54,693$21.4M0.07%-40913F-HRTimeline
MACKENZIE FINANCIAL CORP54,343$21.3M0.03%+18,06813F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC53,695$21M0.09%+7,87313F-HRTimelineGroup
Illinois Municipal Retirement Fund52,801$20.7M0.26%-82313F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding51,572$20.2M+44,543Timeline
CULLINAN ASSOCIATES INC51,412$20.1M1.31%-60013F-HRTimeline
Qube Research & Technologies Ltd51,382$20.1M0.03%+45,70113F-HRTimeline
TUDOR INVESTMENT CORP ET AL51,374$20.1M0.13%new13F-HR/ATimeline
CAPITAL GROUP INVESTMENT MANAGEMENT PTE…group of 2 filers holding51,160$20M-80,876Timeline
VALLEY WEALTH MANAGERS, INC.in group VALLEY WEALTH MANAGERS, INC.49,819$19.5M1.29%+1,13013F-HRTimelineGroup
Smith Group Asset Management, LLC48,857$19.1M1.1%+2,60213F-HRTimeline
IFM Investors Pty Ltd49,484$19.1M0.17%-83313F-HRTimeline
Rhenman & Partners Asset Management AB46,955$18.4M2.03%-14,50013F-HRTimeline
Sanctuary Advisors, LLC46,253$18.1M0.1%-91713F-HR/ATimeline
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S46,057$18M0.28%013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP45,885$18M0.02%-71,11513F-HRTimelineGroup
Calamos Advisors LLCin group Calamos Advisors LLC45,753$17.9M0.07%013F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…45,315$17.7M0.11%-4,93113F-HR/ATimelineGroup
China Universal Asset Management Co., L…45,114$17.7M1.46%+84913F-HRTimeline
LBP AM SA44,279$17.3M0.21%+4,93813F-HRTimeline
USS Investment Management Ltd44,099$17.3M0.08%-5513F-HRTimeline
HighTower Advisors, LLC44,015$17.2M0.02%-12,33213F-HRTimeline
W.G. Shaheen & Associates DBA Whitney &…43,556$17.1M1.55%-25313F-HRTimeline
GROUPAMA ASSET MANAGMENT43,381$17M0.25%-17,91613F-HRTimeline
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…42,881$16.8M0.23%+9,96313F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…42,581$16.7M0.13%-25,59913F-HRTimeline
Utah Retirement Systems42,499$16.6M0.16%-3413F-HRTimeline
Police & Firemen's Retirement System of…41,376$16.2M0.13%+2,34113F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC41,042$16.1M0.01%new13F-HRTimelineGroup
Gradient Investments LLCin group Gradient Investments LLC40,977$16M0.27%+2,96413F-HRTimelineGroup
SEGALL BRYANT & HAMILL, LLC40,971$16M0.21%-1,35713F-HRTimeline
Boston Common Asset Management, LLC40,899$16M0.45%-5,16413F-HRTimeline
ARMISTICE CAPITAL, LLC40,239$15.8M0.49%new13F-HRTimeline
Aristotle Atlantic Partners, LLCin group ARISTOTLE INVESTMENT SERVICES…39,804$15.6M0.45%-5,57213F-HRTimelineGroup
Tweedy, Browne Co LLC39,065$15.3M1.33%+1,81213F-HRTimeline
Ilmarinen Mutual Pension Insurance Co38,800$15.2M0.11%-6,00013F-HRTimeline
Bridgewater Associates, LP38,324$15M0.06%+3,93413F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC37,879$14.8M0.06%+1,44613F-HRTimelineGroup
New York Life Investment Management LLCin group New York Life Investment Mana…37,432$14.7M0.13%-1,46813F-HRTimelineGroup
Wealthfront Advisers LLC37,373$14.6M0.03%-6,54513F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al37,100$14.5M0.09%new13F-HRTimeline
SHELTON CAPITAL MANAGEMENT36,679$14.4M0.31%-16,33613F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P36,522$14.3M0.36%-4,76013F-HRTimeline
Cornerstone Advisors, LLC36,100$14.1M0.47%-50013F-HRTimeline
Andra AP-fonden35,900$14.1M0.18%new13F-HRTimeline
State of Alaska, Department of Revenue35,853$14M0.14%-9,40213F-HRTimeline
iA Global Asset Management Inc.35,842$14M0.19%+68513F-HRTimeline
O'SHAUGHNESSY ASSET MANAGEMENT, LLC35,681$14M0.08%+1,42213F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC35,472$13.9M0.05%+2,45813F-HRTimeline
Vestcor Inc35,266$13.8M0.41%+3,77813F-HRTimeline
ADAMS DIVERSIFIED EQUITY FUND, INC.in group ADAMS DIVERSIFIED EQUITY FUND…35,100$13.7M0.46%013F-HRTimelineGroup
Varma Mutual Pension Insurance Co34,926$13.7M0.09%-1,70013F-HRTimeline
Foster Victor Wealth Advisors, LLC33,857$13.7M0.85%+8,49313F-HRTimeline
FLPUTNAM INVESTMENT MANAGEMENT CO34,676$13.6M0.2%-3,06513F-HRTimeline
BAILARD, INC.34,639$13.6M0.29%-3,50813F-HRTimeline
SAPIENT CAPITAL LLC34,311$13.6M0.21%-1,99913F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC34,361$13.5M0.12%+16,87313F-HRTimeline
MML INVESTORS SERVICES, LLC34,231$13.4M0.04%-2,37613F-HRTimeline
Elo Mutual Pension Insurance Co33,783$13.2M0.22%+49113F-HRTimeline
ODDO BHF ASSET MANAGEMENT SAS33,278$13M0.5%+20,89013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
MCRAE CAPITAL MANAGEMENT INC33,159$13M2.58%+2,70613F-HRTimeline
Galvin, Gaustad & Stein, LLC33,142$13M1.06%+10,25213F-HRTimeline
BARLOW WEALTH PARTNERS, LLC29,880$12.7M1.42%-21,07813F-HRTimeline
Louisiana State Employees Retirement Sy…32,200$12.6M0.21%-10013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\30,856$12.1M0.01%-2,72713F-HRTimelineGroup
Liontrust Investment Partners LLP30,300$11.9M0.17%+3,34613F-HR/ATimeline
Headlands Technologies LLC29,864$11.7M0.93%new13F-HRTimeline
Washington Trust Bank29,809$11.7M0.86%+56613F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Aquatic Capital Management LLC29,596$11.6M0.22%new13F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK29,447$11.5M0.07%-3,96513F-HRTimelineGroup
Apollon Wealth Management, LLCin group Apollon Wealth Management, LLC29,366$11.5M0.2%-39113F-HRTimelineGroup
OREGON PUBLIC EMPLOYEES RETIREMENT FUND29,285$11.5M0.15%+7,10113F-HRTimeline
OPPENHEIMER ASSET MANAGEMENT INC.group of 2 filers holding29,064$11.4M+3,735Timeline
MassMutual Private Wealth & Trust, FSB28,495$11.2M0.28%+1,70413F-HRTimeline
CCM INVESTMENT ADVISERS LLC28,309$11.1M1.09%-1,30613F-HRTimeline
OP Asset Management Ltd28,288$11.1M0.15%+51113F-HR/ATimeline
Y-Intercept (Hong Kong) Ltd27,770$10.9M0.26%new13F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…27,746$10.9M0.11%-1,66013F-HRTimelineGroup
Shelter Mutual Insurance Coin group Shelter Mutual Insurance Co27,600$10.8M2.42%013F-HRTimelineGroup
Steward Partners Investment Advisory, L…27,361$10.7M0.06%-14,19013F-HRTimeline
Avanza Fonder AB27,053$10.6M0.27%+1,62813F-HRTimeline
PROFUND ADVISORS LLC26,395$10.3M0.34%-95813F-HRTimeline
SIG BROKERAGE, LP26,390$10.3M2.6%-6,17613F-HRTimeline
BENDER ROBERT & ASSOCIATES26,330$10.3M2.23%-38213F-HRTimeline
FAGAN ASSOCIATES, INC.26,306$10.3M1.42%+11113F-HRTimeline
ASR Vermogensbeheer N.V.26,294$10.3M0.12%-12513F-HRTimeline
Bogart Wealth, LLC26,149$10.2M0.42%+74213F-HRTimeline
Fisher Asset Management, LLC25,959$10.2M<0.01%+20413F-HRTimeline
MERITAGE PORTFOLIO MANAGEMENT25,940$10.2M0.68%-7,00313F-HRTimeline
Advisors Asset Management, Inc.25,926$10.2M0.17%+84113F-HR/ATimeline
Atria Investments, Inc25,919$10.2M0.12%+2,41813F-HRTimeline
LVM CAPITAL MANAGEMENT LTD/MI25,840$10.1M0.97%-4,23013F-HRTimeline
Generate Investment Management Ltd25,734$10.1M0.51%new13F-HRTimeline
ARK Investment Management LLCin group ARK Investment Management LLC25,665$10.1M0.06%+1,60213F-HRTimelineGroup
YOUSIF CAPITAL MANAGEMENT, LLC25,662$10.1M0.11%-45513F-HRTimeline
Kestra Advisory Services, LLCgroup of 3 filers holding25,390$9.94M+4,367Timeline
PINNACLE ASSOCIATES LTD25,367$9.93M0.13%+25913F-HRTimeline
Caprock Group, LLC25,216$9.86M0.24%13F-HRTimeline
Biondo Investment Advisors, LLC25,075$9.82M1.23%+14613F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC24,949$9.77M0.04%-26,00713F-HRTimeline
Americana Partners, LLC24,468$9.58M0.29%+12,13413F-HRTimeline
PEAK6 LLCin group PEAK6 LLC24,416$9.56M0.24%-6,04013F-HR/ATimelineGroup
FIFTH THIRD BANK, NATIONAL ASSOCIATIONgroup of 2 filers holding24,023$9.41M-2,027Timeline
Generali Asset Management SPA SGR23,569$9.23M0.2%+6,94213F-HRTimeline
CARY STREET PARTNERS ASSET MANAGEMENT L…group of 2 filers holding23,315$9.13M-476Timeline
Kentucky Retirement Systemsgroup of 2 filers holding22,915$8.97M-693Timeline
GW HENSSLER & ASSOCIATES LTD22,791$8.93M0.45%+2813F-HRTimeline
SOMERVILLE KURT F22,643$8.87M1.47%-54313F-HRTimeline
Public Sector Pension Investment Board22,418$8.78M0.03%+2,74413F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC22,180$8.69M0.19%+2,77013F-HRTimeline
Norinchukin Bank, Thein group Norinchukin Bank, The22,026$8.63M0.12%+9013F-HRTimelineGroup
EULAV Asset Management22,000$8.62M0.2%-70013F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co21,921$8.59M0.1%+4,40213F-HRTimelineGroup
Gotham Asset Management, LLC21,888$8.57M0.04%+53213F-HRTimeline
Modera Wealth Management, LLC21,853$8.56M0.1%-1,25213F-HRTimeline
Diversify Advisory Services, LLCgroup of 2 filers holding19,524$8.32M-755Timeline
Telos Capital Management, Inc.21,188$8.3M0.8%+1,94613F-HRTimeline
CAMDEN NATIONAL BANK20,892$8.18M1.14%+43013F-HRTimeline
&PARTNERS27,949$8.16M0.05%+2,80913F-HRTimeline
WOLVERINE TRADING, LLC20,449$8.08M0.16%+2,85413F-HRTimeline
Prosight Management, LP20,500$8.03M1.93%new13F-HRTimeline
UniSuper Management Pty Ltd20,495$8.03M0.05%+3,84713F-HRTimeline
AIMZ Investment Advisors, LLC20,361$7.97M2.5%-36513F-HRTimeline
Azimuth Capital Investment Management L…20,348$7.97M0.29%-68413F-HRTimeline
Waverly Advisors, LLC20,248$7.93M0.08%+10313F-HRTimeline
Heirloom Wealth Management19,966$7.82M1.89%+33313F-HRTimeline
GRANDFIELD & DODD, LLC19,820$7.76M0.44%+1,53313F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV18,784$7.36M0.01%+26113F-HRTimeline
BRIDGER MANAGEMENT, LLC18,778$7.35M3.96%013F-HRTimeline
MIZUHO SECURITIES USA LLCin group MIZUHO FINANCIAL GROUP INC18,674$7.3M0.15%+92413F-HRTimelineGroup
BLAIR WILLIAM & CO/IL17,990$7.05M0.02%-8,08713F-HRTimeline
Sterling Capital Management LLC17,478$6.85M0.1%-2,96613F-HRTimeline
Broderick Brian C17,251$6.76M1.28%-42013F-HRTimeline
SILVERCREST ASSET MANAGEMENT GROUP LLC16,959$6.64M0.04%+613F-HRTimeline
PRUDENTIAL PLCin group PRUDENTIAL PLC16,568$6.49M0.05%-2,95713F-HRTimelineGroup
NORTHWESTERN MUTUAL INVESTMENT MANAGEME…group of 2 filers holding16,478$6.45M-3,247Timeline
Fulcrum Capital LLC16,256$6.37M1.31%+45813F-HRTimeline
Torray Investment Partners LLC16,255$6.37M0.86%-62413F-HRTimeline
Madison Asset Management, LLCin group Madison Asset Management, LLC16,201$6.34M0.07%+2,00913F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP16,101$6.31M0.08%new13F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.16,000$6.27M0.06%-18,61513F-HRTimelineGroup
NIA IMPACT ADVISORS, LLC15,933$6.24M2.03%+4613F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.15,833$6.2M0.08%-3,20313F-HRTimeline
Trifecta Capital Advisors, LLC15,833$6.2M0.94%+49313F-HRTimeline
ANDERSON HOAGLAND & CO15,767$6.17M0.55%-3,88013F-HRTimeline
Aptus Capital Advisors, LLC15,755$6.17M0.06%+1,86813F-HRTimeline
Baldwin Investment Management, LLC15,748$6.17M0.71%+1,20713F-HRTimeline
Janney Capital Management LLC15,707$6.15M0.38%-52413F-HRTimeline
GAMCO Investors (Gabelli)group of 2 filers holding15,514$6.08M-1,327Timeline
PUZO MICHAEL J15,501$6.07M1.66%+16113F-HRTimeline
Northwest & Ethical Investments L.P.15,315$6M0.14%+22613F-HRTimeline
Investment Management Corp of Ontario15,235$5.97M0.09%+3,56013F-HRTimeline
PREVAIL INNOVATIVE WEALTH ADVISORS, LLC15,200$5.95M1.16%new13F-HRTimeline
PARK AVENUE SECURITIES LLCin group PARK AVENUE SECURITIES LLC15,043$5.89M0.05%-31913F-HRTimelineGroup
HARTFORD INVESTMENT MANAGEMENT CO15,022$5.88M0.18%-47613F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding15,010$5.88M-201Timeline
Engineers Gate Manager LP14,843$5.81M0.07%new13F-HRTimeline
Atlantic Union Bankshares Corpin group Atlantic Union Bankshares Corp14,688$5.75M0.11%+5,74113F-HRTimelineGroup
Tidal Investments LLCin group Tidal Investments LLC14,632$5.73M0.02%+36713F-HRTimelineGroup
Meiji Yasuda Life Insurance Cogroup of 2 filers holding14,538$5.69M-150Timeline
PRINCETON CAPITAL MANAGEMENT LLC14,438$5.65M1.52%-3713F-HRTimeline
Knuff & Co LLC14,184$5.56M1.61%+18813F-HRTimeline
FIRST HORIZON CORP14,121$5.53M0.26%13F-HRTimeline
Cambridge Investment Research Advisors,…14,117$5.53M0.02%-3,21213F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…14,022$5.49M0.15%-9,45613F-HRTimelineGroup
Sivik Global Healthcare LLC14,000$5.48M2.88%new13F-HRTimeline
Sequoia Financial Advisors, LLC13,980$5.48M0.03%-39313F-HRTimeline
Ethic Inc.13,971$5.47M0.09%+2,47613F-HRTimeline
New Age Alpha Advisors, LLC13,939$5.46M0.23%-1,76113F-HRTimeline
OMERS ADMINISTRATION Corp13,754$5.39M0.04%013F-HRTimeline
Empowered Funds, LLC13,583$5.32M0.05%+3,76113F-HRTimeline
Metis Global Partners, LLC13,424$5.26M0.12%-69413F-HRTimeline
Princeton Global Asset Management LLC13,359$5.23M0.87%-1,66613F-HRTimeline
Beacon Pointe Advisors, LLC13,284$5.2M0.04%-2,74513F-HRTimeline
Vident Advisory, LLCin group Vident Advisory, LLC13,222$5.18M0.05%-5,27813F-HRTimelineGroup
OSSIAM12,940$5.07M0.07%+8,34013F-HRTimeline
Fisher Funds Management LTD12,898$5.05M0.13%013F-HRTimeline
Gulf International Bank (UK) Ltd12,879$5.04M0.17%-25513F-HRTimeline
Maryland State Retirement & Pension Sys…12,846$5.03M0.11%+34613F-HRTimeline