Skip to content
Disclosery

SYRE SPYRE THERAPEUTICS INC

Follow

COM NEW (common), issuer CIK 1636282

256 managers (267 13F filers) reported a position in SYRE shares at 2026-06-30, 95,831,124 shares in all. 88 filers opened a position and 21 filers sold out during the quarter.

Managers
256
13F filers
267
New
88
Added
105
Reduced
56
Sold out
21
Shares held by filers
95,831,124

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
CIBC Asset Management Inc2,429$216K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,347$208K<0.01%+43113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,338$208K<0.01%-91213F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC2,310$205K<0.01%-3,54813F-HRTimeline
Bayforest Capital Ltd2,305$205K0.19%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC2,296$203K<0.01%new13F-HRTimelineGroup
CFC Planning Co LLC2,277$202K0.12%new13F-HRTimeline
Fulcrum Asset Management LLP2,114$191K0.02%new13F-HRTimeline
ABS Investment Management LLC89$186K0.12%13F-HRTimeline
Nykredit A/Sin group Nykredit A/S1,953$173K<0.01%13F-HR/ATimelineGroup
Mitsubishi UFJ Trust & Banking Corpin group Mitsubishi UFJ Trust & Bankin…1,844$164K<0.01%new13F-HRTimelineGroup
KBC Group NVin group KBC Group NV1,796$159K<0.01%+42413F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,664$148K<0.01%-7913F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…1,589$141K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\1,507$134K<0.01%+1,41013F-HRTimelineGroup
Farther Finance Advisors, LLC1,129$100K<0.01%+1,05513F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…914$81.1K<0.01%+79113F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …897$79.6K<0.01%+913F-HRTimelineGroup
Union Bancaire Privee, UBP SA880$79.3K<0.01%-3,00013F-HRTimeline
Kemnay Advisory Services Inc.741$65.8K0.01%+16713F-HRTimeline
Parallel Advisors, LLC720$63.9K<0.01%+68813F-HRTimeline
GAMMA Investing LLC663$58.9K<0.01%+14013F-HRTimeline
Pacer Advisors, Inc.614$55K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.400$35.5K<0.01%+11213F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…345$30.6K<0.01%+26613F-HRTimelineGroup
SIMPLEX TRADING, LLC278$24.7K<0.01%new13F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK270$24K<0.01%new13F-HRTimelineGroup
Sterling Capital Management LLC262$23.3K<0.01%-78913F-HRTimeline
Allworth Financial LP226$20.1K<0.01%+10913F-HRTimeline
Axiom Investment Management LLC200$17.8K0.01%new13F-HRTimeline
Arax Advisory Partners169$15K<0.01%+15113F-HRTimeline
J.Safra Asset Management Corp167$14.8K<0.01%new13F-HRTimeline
IFG Advisory, LLC161$14.3K<0.01%new13F-HRTimeline
Smartleaf Asset Management LLC157$14.2K<0.01%013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/124$11K<0.01%new13F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP103$9.05K<0.01%new13F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC99$8.79K<0.01%013F-HRTimeline
Larson Financial Group LLC63$5.59K<0.01%+2713F-HRTimeline
SIGNATUREFD, LLC59$5.24K<0.01%-1113F-HRTimeline
Parkside Financial Bank & Trust45$4K<0.01%+1013F-HRTimeline
MEEDER ASSET MANAGEMENT INCin group Meeder Advisory Services, Inc.30$2.66K<0.01%new13F-HRTimelineGroup
IFP Advisors, Inc24$2.13K<0.01%013F-HRTimeline
Bare Financial Services, Inc16$1.42K<0.01%013F-HRTimeline
Covestor Ltd13$1K<0.01%+913F-HRTimeline
Ares Financial Consulting, LLC11$977<0.01%new13F-HRTimeline
Physician Wealth Advisors, Inc.5$444<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.5$444<0.01%013F-HRTimeline
Stone House Investment Management, LLC4$355<0.01%new13F-HRTimeline
Hughes Financial Services, LLC4$355<0.01%new13F-HRTimeline
Keating Financial Advisory Services, In…4$355<0.01%013F-HRTimeline
Silver Grove Financial Group, Inc.3$266<0.01%new13F-HRTimeline
Caitong International Asset Management …2$178<0.01%-28413F-HRTimeline
Quarry LP2$178<0.01%new13F-HRTimeline
Essential Partners LLC2$178<0.01%013F-HRTimeline
ZIONS BANCORPORATION, NATIONAL ASSOCIAT…1$89<0.01%new13F-HRTimeline
MassMutual Private Wealth & Trust, FSB0$00%-313F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • Paradigm Biocapital Advisors LP and 3 other reporting persons reported 4,457,450 SYRE shares, 5.1% of the class, as of 2026-09-24, in a 13G filed 2026-10-01. 0001104659-26-112828

    Accepted , ingested