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Disclosery

SLN SILENCE THERAPEUTICS PLC

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ADS (ADR), issuer CIK 1479615

53 managers (54 13F filers) reported a position in SLN shares at 2025-09-30, 19,704,453 shares in all. 6 filers opened a position and 7 filers sold out during the quarter.

Managers
53
13F filers
54
New
6
Added
15
Reduced
16
Sold out
7
Shares held by filers
19,704,453

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TCG Crossover Management, LLC3,033,560$15.7M0.77%013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.2,911,438$15.1M0.59%013F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC2,164,777$11.2M1.09%013F-HRTimelineGroup
Lombard Odier Asset Management (USA) Co…1,844,948$7.12M1.61%-4,78613F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY1,207,724$6.27M<0.01%-4,03413F-HR/ATimelineGroup
Vivo Capital, LLC1,105,454$5.74M0.46%013F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…1,042,427$5.41M0.33%013F-HRTimelineGroup
Frazier Life Sciences Management, L.P.970,130$5.03M0.15%013F-HRTimeline
Nextech Invest Ltd.952,400$4.94M0.75%013F-HRTimeline
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.801,306$4.16M0.08%+12,26713F-HR/ATimelineGroup
5AM Venture Management, LLC476,200$2.47M0.91%013F-HRTimeline
SG Americas Securities, LLC308,289$1.6M0.01%-4213F-HRTimeline
UBS Group AGin group UBS Group AG307,363$1.6M<0.01%+78,85413F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC298,512$1.55M<0.01%+99,86513F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC279,637$1.45M0.04%+27,21613F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC900,784$1.31M0.26%+27,21613F-HRTimelineGroup
M28 Capital Management LP185,100$961K1.41%013F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC172,873$909K<0.01%+3913F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/153,782$798K<0.01%+7,97013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding105,847$549K+6,935Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP83,219$432K<0.01%-92,64313F-HRTimelineGroup
Woodline Partners LP62,459$324K<0.01%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.61,832$321K<0.01%-106,40313F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.62,171$299K<0.01%-7,21013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC29,538$153K<0.01%013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC22,644$118K<0.01%new13F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC21,505$112K<0.01%new13F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…20,374$106K0.03%+3,53713F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC18,643$96.8K0.01%013F-HRTimelineGroup
HRT FINANCIAL LP10,887$56K<0.01%new13F-HRTimeline
EHP Funds Inc.10,673$55.4K0.07%new13F-HRTimeline
Cambridge Investment Research Advisors,…10,194$53K<0.01%013F-HRTimeline
GAMMA Investing LLC9,915$51.5K<0.01%+1,58213F-HRTimeline
China Universal Asset Management Co., L…8,232$42.7K<0.01%-1,21413F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO7,766$40.3K<0.01%+48313F-HR/ATimelineGroup
WEXFORD CAPITAL LP7,708$40K0.01%-19,44113F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC7,136$37K<0.01%+10113F-HR/ATimelineGroup
RHUMBLINE ADVISERS5,865$30.4K<0.01%-33113F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC4,218$21K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/3,531$18.3K<0.01%-1,56413F-HR/ATimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,500$13.8K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,447$12.7K<0.01%+1913F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…1,816$9.43K<0.01%-113F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC1,773$9.2K<0.01%-1,70113F-HRTimelineGroup
Parallel Advisors, LLC1,300$6.75K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,136$6K<0.01%-1,32613F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.978$5.08K<0.01%-18713F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS600$3.11K<0.01%-10013F-HRTimelineGroup
SIMPLEX TRADING, LLC651$3K<0.01%-1613F-HRTimeline
Steward Partners Investment Advisory, L…100$519<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…45$234<0.01%new13F-HRTimelineGroup
SBI Securities Co., Ltd.29$151<0.01%+113F-HRTimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC17$88<0.01%013F-HRTimelineGroup