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Disclosery

SLN SILENCE THERAPEUTICS PLC

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ADS (ADR), issuer CIK 1479615

55 managers (56 13F filers) reported a position in SLN shares at 2025-06-30, 19,759,651 shares in all. 9 filers opened a position and 13 filers sold out during the quarter.

Managers
55
13F filers
56
New
9
Added
12
Reduced
19
Sold out
13
Shares held by filers
19,759,651

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TCG Crossover Management, LLC3,033,560$17.6M2.01%013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.2,911,438$16.9M0.87%+121,60513F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC2,164,777$12.6M1.34%-50,17013F-HRTimelineGroup
Lombard Odier Asset Management (USA) Co…1,849,734$7.81M1.96%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY1,211,758$7.03M<0.01%-788,34713F-HRTimelineGroup
Vivo Capital, LLC1,105,454$6.41M0.66%013F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…1,042,427$6.05M0.43%013F-HRTimelineGroup
Frazier Life Sciences Management, L.P.970,130$5.63M0.23%-178,46113F-HRTimeline
Nextech Invest Ltd.952,400$5.52M1.05%013F-HRTimeline
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.789,039$4.58M0.11%+15,19413F-HRTimelineGroup
5AM Venture Management, LLC476,200$2.76M1.06%013F-HRTimeline
SG Americas Securities, LLC308,331$1.79M0.01%+4213F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC252,421$1.46M0.04%+2,40913F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC873,568$1.4M0.46%new13F-HRTimelineGroup
UBS Group AGin group UBS Group AG228,509$1.33M<0.01%-91,00513F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC198,647$1.15M<0.01%-198,21513F-HRTimelineGroup
M28 Capital Management LP185,100$1.07M1.83%013F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC172,834$1.02M<0.01%013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP175,862$1.02M<0.01%-52,55613F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.168,235$976K<0.01%-12,20013F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/145,812$846K<0.01%-12,78113F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding98,912$574K-26,296Timeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.69,381$402K<0.01%-2,11613F-HR/ATimelineGroup
Woodline Partners LP62,459$362K<0.01%-72,03313F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC37,813$219K<0.01%new13F-HRTimelineGroup
Saturn V Capital Management LP34,737$201K0.08%-697,72613F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC29,538$171K<0.01%+12113F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…27,797$161K<0.01%new13F-HRTimelineGroup
WEXFORD CAPITAL LP27,149$157K0.04%new13F-HRTimeline
Massar Capital Management, LP19,863$115K0.09%new13F-HR/ATimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC18,643$108K0.02%013F-HRTimelineGroup
Rathbones Group PLC18,421$107K<0.01%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…16,837$97.7K0.03%-8,03513F-HRTimelineGroup
Beacon Pointe Advisors, LLC11,615$67.4K<0.01%new13F-HRTimeline
Cambridge Investment Research Advisors,…10,194$59K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…9,446$54.8K0.01%+1413F-HRTimeline
GAMMA Investing LLC8,333$48.3K<0.01%+4,77313F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO7,283$42.2K<0.01%-28,13113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC7,035$40.8K<0.01%+18113F-HR/ATimelineGroup
RHUMBLINE ADVISERS6,196$35.9K<0.01%+4,32113F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/5,095$29.6K<0.01%-59,79113F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC3,474$20.1K<0.01%-57,59713F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,500$14.5K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,428$14.1K<0.01%+6113F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,462$14K<0.01%-1,80113F-HR/ATimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…1,817$10.5K<0.01%+24413F-HRTimelineGroup
Parallel Advisors, LLC1,300$7.54K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,165$6.76K<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS700$4.06K<0.01%-4,08813F-HRTimelineGroup
SIMPLEX TRADING, LLC667$3K<0.01%+41613F-HRTimeline
Steward Partners Investment Advisory, L…100$580<0.01%013F-HRTimeline
SBI Securities Co., Ltd.28$162<0.01%013F-HRTimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC17$99<0.01%new13F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…10$58<0.01%new13F-HRTimelineGroup
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.