Deep Track Capital, LP More: the full row for Deep Track Capital, LP 3,352,804 $82.7M 1.71% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 2,470,845 $60.9M <0.01% +231,911 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 2,208,604 $54.5M 0.58% 0 13F-HR Timeline Group TCG Crossover Management, LLC More: the full row for TCG Crossover Management, LLC 1,839,489 $45.3M 1.3% +94,474 13F-HR Timeline Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 1,500,000 $37M 2.14% 0 13F-HR Timeline Group Caligan Partners LP More: the full row for Caligan Partners LP 1,438,070 $34.6M 2.45% new 13F-HR Timeline Spruce Street Capital LP More: the full row for Spruce Street Capital LP 1,376,159 $33.6M 8.09% +370,566 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 1,427,568 $33.2M <0.01% -183,914 13F-HR/A Timeline Group Trails Edge Capital Partners, LP More: the full row for Trails Edge Capital Partners, LP 1,319,362 $32.5M 7.66% -76,246 13F-HR Timeline VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 1,173,329 $28.9M new Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 1,052,894 $26M 1.62% +377,894 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 923,694 $22.8M 0.04% +26,888 13F-HR Timeline Group Logos Global Management LP More: the full row for Logos Global Management LP 915,000 $22.6M 1.16% -285,000 13F-HR Timeline Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 863,947 $21.3M 0.06% +188,947 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 800,000 $19.7M 1.64% 0 13F-HR/A Timeline Nan Fung Group Holdings Ltd More: the full row for Nan Fung Group Holdings Ltd 630,657 $15.6M 12.82% +330,657 13F-HR Timeline JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 538,216 $13.3M 0.01% -283,636 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 518,228 $12.8M <0.01% +76,774 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 504,373 $12.4M <0.01% +254,343 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 416,906 $10.3M 0.01% +9,238 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 363,799 $8.97M <0.01% +60,684 13F-HR Timeline Group GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 300,000 $7.4M 1.81% new 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 222,508 $5.49M <0.01% +643 13F-HR Timeline Group BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 200,000 $4.93M 0.03% 0 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 186,095 $4.59M <0.01% +8,479 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 173,595 $4.28M 1.18% +33,488 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 154,398 $3.81M <0.01% +10,432 13F-HR Timeline Group Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 150,000 $3.7M 0.2% +50,000 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 137,932 $3.4M <0.01% +87,219 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 136,966 $3.38M <0.01% new 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 108,307 $2.67M <0.01% -85,237 13F-HR/A Timeline Group Eversept Partners, LP More: the full row for Eversept Partners, LP 100,198 $2.47M 0.16% new 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 72,067 $1.78M <0.01% +70,542 13F-HR Timeline Group Boxer Capital Management, LLC in group Boxer Capital Management, LLC More: the full row for Boxer Capital Management, LLC 70,000 $1.73M 0.23% 0 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 65,429 $1.61M <0.01% new 13F-HR/A Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 52,640 $1.3M <0.01% new 13F-HR Timeline Group STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 50,000 $1.23M 0.24% new 13F-HR/A Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 47,280 $1.17M <0.01% +22,639 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 45,457 $1.12M <0.01% +4,940 13F-HR Timeline Group ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 28,919 $713K 0.51% -1,081 13F-HR Timeline Calamos Advisors LLC in group Calamos Advisors LLC More: the full row for Calamos Advisors LLC 24,063 $593K <0.01% new 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 22,966 $566K <0.01% 0 13F-HR Timeline Group Focus Partners Wealth in group Focus Partners Wealth More: the full row for Focus Partners Wealth 19,815 $489K <0.01% -280 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 17,103 $422K <0.01% +820 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 16,618 $410K <0.01% -27,140 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 15,359 $379K <0.01% +2,061 13F-HR Timeline Group MEYER HANDELMAN CO More: the full row for MEYER HANDELMAN CO 15,094 $372K 0.01% new 13F-HR Timeline Opaleye Management Inc. More: the full row for Opaleye Management Inc. 14,506 $358K 0.05% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 13,229 $327K <0.01% +2,155 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 12,720 $314K <0.01% 0 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 11,104 $274K <0.01% 0 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 10,729 $265K <0.01% -226 13F-HR Timeline Group Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 10,000 $247K 0.01% 0 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 9,931 $245K <0.01% new 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 9,170 $226K <0.01% +204 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 8,623 $213K <0.01% -13,680 13F-HR/A Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 6,100 $150K <0.01% new 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 6,041 $149K <0.01% +1,616 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 5,569 $137K <0.01% +5,134 13F-HR Timeline Group STRS OHIO More: the full row for STRS OHIO 5,100 $126K <0.01% +1,700 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 5,000 $123K <0.01% 0 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 4,530 $112K <0.01% -25,685 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 4,052 $99.9K <0.01% +45 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 1,723 $42.5K <0.01% -155 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,661 $41K <0.01% +300 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 1,562 $38.5K <0.01% 0 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1,041 $25.7K <0.01% -143 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 368 $9.07K <0.01% -224 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 162 $4K <0.01% +148 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 145 $3.58K <0.01% new 13F-HR Timeline Group MassMutual Private Wealth & Trust, FSB More: the full row for MassMutual Private Wealth & Trust, FSB 54 $1.33K <0.01% new 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 29 $715 <0.01% +21 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 1 $25 <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 1 $25 <0.01% new 13F-HR/A Timeline Group