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Disclosery

INSP INSPIRE MED SYS INC

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Stock (common), issuer CIK 1609550

338 managers (344 13F filers) reported a position in INSP shares at 2025-12-31, 33,884,157 shares in all. 77 filers opened a position and 69 filers sold out during the quarter.

Managers
338
13F filers
344
New
77
Added
114
Reduced
114
Sold out
69
Shares held by filers
33,884,157

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.3,550,848$327M0.01%+3,65313F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding2,955,611$273M-44,476Timeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,211,091$204M0.04%new13F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,505,872$139M1.78%+458,17813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY1,259,762$116M0.01%+809,12113F-HR/ATimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,212,162$112M0.08%+853,30513F-HRTimelineGroup
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC1,161,285$107M0.3%-136,28813F-HRTimeline
STATE STREET CORPin group STATE STREET CORP918,504$84.7M<0.01%-60,80513F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding874,645$80.7M-426,690Timeline
Artisan Partners Limited Partnership785,742$72.5M0.11%+259,50013F-HRTimeline
FULLER & THALER ASSET MANAGEMENT, INC.668,099$61.6M0.21%new13F-HR/ATimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson562,331$51.9M0.02%-104,74713F-HRTimelineGroup
BRAIDWELL LP540,890$49.9M1.6%-342,85713F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP531,079$49M0.05%+396,81013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\516,816$47.7M0.02%+509,62813F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC511,318$47.2M0.03%-1,237,09113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC491,750$45.4M<0.01%-13,23713F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc460,901$42.5M0.07%+64,56113F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS454,810$41.9M0.03%-67,37013F-HRTimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC440,205$40.6M0.63%+183,54713F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC410,768$37.9M0.06%+255,76813F-HRTimeline
Amundiin group Amundi364,622$33.6M0.01%+109,49813F-HRTimelineGroup
Driehaus Capital Management LLC348,500$32.1M0.22%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP341,397$31.5M0.01%-2,32113F-HRTimelineGroup
BAMCO INC /NY/in group Baron Capital337,486$31.1M0.08%+147,46313F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/308,171$28.4M<0.01%+283,24313F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.307,588$28.4M0.23%new13F-HRTimelineGroup
Soleus Capital Management, L.P.299,399$27.6M1.17%-428,78913F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC284,885$26.3M<0.01%+21,66113F-HR/ATimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC277,199$25.6M0.03%+205,74813F-HRTimelineGroup
Jain Global LLC268,250$24.7M0.24%+264,35413F-HRTimeline
Assenagon Asset Management S.A.264,999$24.4M0.04%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.261,374$24.1M<0.01%+168,58713F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources231,438$21.3M0.01%-65,80713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp215,780$19.9M<0.01%+48,90413F-HRTimelineGroup
Trexquant Investment LP213,249$19.7M0.18%new13F-HRTimeline
Regal Partners Ltdin group Regal Partners Ltd211,304$19.5M1.12%+109,59013F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/210,126$19.4M<0.01%-78,70213F-HRTimelineGroup
Champlain Investment Partners, LLC203,098$18.7M0.19%-203,96113F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC202,140$18.6M0.01%-154,66813F-HRTimelineGroup
KEYBANK NATIONAL ASSOCIATION/OHin group KEYBANK NATIONAL ASSOCIATION/…200,042$18.4M0.07%+3713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP197,456$18.2M<0.01%+7,69213F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co194,155$17.9M<0.01%+1,02113F-HRTimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC188,100$17.3M0.06%+99,79913F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management187,226$17.3M0.03%-427,13313F-HRTimelineGroup
Nuveen, LLCin group TIAA159,421$14.7M<0.01%+111,56913F-HRTimelineGroup
FRONTIER CAPITAL MANAGEMENT CO LLC142,007$13.1M0.14%-20,28813F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.141,964$13.1M0.13%+27,06313F-HRTimelineGroup
FMR LLCin group FMR LLC137,306$12.7M<0.01%-612,00613F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…136,420$12.6M0.03%-2,89713F-HRTimeline
Rock Springs Capital Management LP131,000$12.1M0.62%+20,50013F-HRTimeline
NORGES BANK129,570$12M<0.01%new13F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding125,519$11.6M-3,655Timeline
CAPITAL FUND MANAGEMENT S.A.122,706$11.3M0.11%+49,70913F-HRTimeline
HRT FINANCIAL LP121,761$11.2M0.04%+76,08013F-HRTimeline
BROWN CAPITAL MANAGEMENT LLC119,935$11.1M0.91%-158,10513F-HRTimeline
Rheos Capital Works Inc.117,400$10.8M0.69%+65,00013F-HRTimeline
WASATCH ADVISORS LP116,068$10.7M0.06%-19,84613F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding113,196$10.4MnewTimeline
TUDOR INVESTMENT CORP ET AL112,873$10.4M0.06%new13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD105,500$9.73M0.01%+65,90013F-HRTimeline
Bellevue Group AGin group Bellevue Group AG100,761$9.29M0.18%+42,11313F-HRTimelineGroup
RIVERBRIDGE PARTNERS LLC97,111$8.96M0.17%-6,46013F-HRTimeline
Public Sector Pension Investment Board91,472$8.44M0.03%-13,51213F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC91,277$8.42M<0.01%+2,20613F-HRTimelineGroup
ING GROEP NV88,300$8.14M0.05%+74,80013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC85,655$7.9M<0.01%+77,00513F-HRTimelineGroup
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA81,986$7.56M0.04%13F-HRTimelineGroup
Walleye Capital LLCgroup of 2 filers holding80,820$7.45M-51,004Timeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …76,028$7.01M<0.01%new13F-HRTimelineGroup
Integral Health Asset Management, LLC75,000$6.92M0.35%-45,00013F-HRTimeline
Bridgewater Associates, LP71,727$6.62M0.02%-17,22513F-HRTimeline
Y-Intercept (Hong Kong) Ltd70,635$6.51M0.15%-28,41413F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc69,756$6.43M<0.01%-14,52413F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND68,774$6.34M0.01%+18,52713F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A67,695$6.24M0.02%-57,56013F-HRTimelineGroup
RHUMBLINE ADVISERS65,894$6.08M<0.01%-1,30613F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding65,715$6.06M+8,563Timeline
Voleon Capital Management LP63,627$5.87M0.13%-14,89113F-HRTimeline
MAIRS & POWER INC57,616$5.31M0.05%-7,83013F-HRTimeline
Swiss National Bank55,500$5.12M<0.01%+1,10013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding50,997$4.7M-93,886Timeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO50,940$4.7M<0.01%+34,51513F-HRTimelineGroup
Gotham Asset Management, LLC48,547$4.48M0.02%+19,45713F-HRTimeline
ALGERT GLOBAL LLC46,250$4.27M0.07%+22,76313F-HR/ATimeline
XTX Topco Ltdin group XTX Topco Ltd45,783$4.22M0.11%+38,49413F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO45,388$4.19M<0.01%-34,98613F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC44,981$4.15M0.01%-44,62413F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC43,328$4M<0.01%-21013F-HR/ATimelineGroup
Man Group plcin group Man Group plc41,425$3.82M0.01%-42,42013F-HRTimelineGroup
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA40,042$3.69M0.01%+15,84413F-HRTimelineGroup
ExodusPoint Capital Management, LP38,896$3.59M0.04%+6,07513F-HRTimeline
SG Americas Securities, LLC38,449$3.55M<0.01%+30,69513F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …38,404$3.54M0.01%+34,88113F-HRTimelineGroup
Bullseye Asset Management LLC36,128$3.33M1.8%013F-HRTimeline
Rhenman & Partners Asset Management AB35,800$3.3M0.31%-25,20013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC34,672$3.2M<0.01%-7,65613F-HRTimelineGroup
EFG International AGin group EFG International AG33,813$3.11M0.06%13F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC32,549$3M<0.01%-3,27713F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD31,469$2.9M0.01%-41,63513F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…31,069$2.87M0.02%-15,29713F-HRTimeline
ALLIANCEBERNSTEIN L.P.30,636$2.83M<0.01%+23,86313F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC30,622$2.82M<0.01%new13F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…29,990$2.77M<0.01%-95013F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…27,276$2.52M<0.01%+7,86113F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC27,040$2.49M<0.01%-22,37713F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…26,186$2.42M<0.01%-11713F-HRTimeline
THORNBURG INVESTMENT MANAGEMENT INC25,197$2.32M0.03%+4,83313F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP25,096$2.31M0.05%new13F-HRTimeline
Polar Asset Management Partners Inc.25,000$2.31M0.05%new13F-HRTimeline
Schonfeld Strategic Advisors LLC24,947$2.3M0.01%+19,79413F-HRTimeline
BANQUE PICTET & CIE SA24,474$2.26M0.02%+21,74713F-HRTimeline
TD Asset Management Inc23,800$2.2M<0.01%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC23,675$2.18M<0.01%-1,15513F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC23,415$2.15M<0.01%+6,76913F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co22,993$2.12M<0.01%013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …21,940$2.03M<0.01%+16,69313F-HRTimelineGroup
Baird Financial Group, Inc.in group Baird Financial Group, Inc.21,910$2.02M<0.01%-3,23913F-HRTimelineGroup
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…21,855$2.02M0.14%+3,56713F-HRTimelineGroup
NEW YORK STATE TEACHERS RETIREMENT SYST…21,595$1.99M<0.01%+50513F-HRTimeline
Aquatic Capital Management LLC21,535$1.99M0.06%-15,52313F-HRTimeline
COMERICA BANK21,093$1.95M0.01%+6,69913F-HRTimeline
Engineers Gate Manager LP19,204$1.77M0.02%+16,26213F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC18,636$1.72M0.02%+7,64313F-HRTimelineGroup
Edgestream Partners, L.P.17,953$1.66M0.05%-5,00313F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC16,453$1.52M<0.01%+4,33513F-HRTimelineGroup
Exit Wealth Advisors, LLC.16,230$1.5M0.88%new13F-HRTimeline
GILDER GAGNON HOWE & CO LLC15,241$1.41M0.01%-2,35913F-HRTimeline
State of Alaska, Department of Revenue15,096$1.39M0.01%-9913F-HRTimeline
Parkman Healthcare Partners LLC15,000$1.38M0.13%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC15,000$1.38M0.1%+9,00013F-HR/ATimelineGroup
OMERS ADMINISTRATION Corp14,553$1.34M0.01%new13F-HRTimeline
FORA Capital, LLC14,266$1.32M0.16%+5,33813F-HRTimeline
LPL Financial LLC13,992$1.29M<0.01%+2,79713F-HRTimeline
Dynamic Technology Lab Private Ltd13,883$1.28M0.29%+9,60513F-HRTimeline
State of Tennessee, Department of Treas…16,697$1.27M<0.01%-60013F-HRTimeline
CONGRESS ASSET MANAGEMENT CO13,067$1.21M0.01%-43413F-HRTimeline
Quantinno Capital Management LP13,048$1.2M<0.01%+1,26813F-HRTimeline
Cambridge Investment Research Advisors,…12,592$1.16M<0.01%new13F-HRTimeline
Louisiana State Employees Retirement Sy…12,100$1.12M0.02%-30013F-HRTimeline
Police & Firemen's Retirement System of…11,823$1.09M0.01%-70913F-HRTimeline
Treasurer of the State of North Carolina11,342$1.05M<0.01%-1,51813F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC11,322$1.04M<0.01%-11,84513F-HRTimeline
NORDEA INVESTMENT MANAGEMENT ABin group NORDEA INVESTMENT MANAGEMENT …11,388$1.04M<0.01%-1,23613F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…11,171$1.03M<0.01%+4,87013F-HRTimelineGroup
Verition Fund Management LLC11,106$1.02M0.01%-60,58913F-HRTimeline
LECAP ASSET MANAGEMENT LTD11,010$1.02M0.4%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA10,984$1.01M<0.01%-2,92813F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.10,875$1M<0.01%-3,18013F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…10,785$995K0.02%-2,44213F-HRTimelineGroup
Handelsbanken Fonder AB9,800$904K<0.01%+1,90013F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…9,423$869K<0.01%-2,66713F-HRTimelineGroup
AMALGAMATED BANK9,270$855K0.01%+5813F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…9,265$855K<0.01%+50713F-HRTimeline
Hilltop Holdings Inc.in group Hilltop Holdings Inc.9,244$853K0.05%new13F-HRTimelineGroup
Campbell & CO Investment Adviser LLC9,220$850K0.04%+6,48013F-HRTimeline
GSA CAPITAL PARTNERS LLP9,215$850K0.07%new13F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP9,156$844K0.04%new13F-HRTimeline
Palo Alto Investors LP8,772$809K0.11%new13F-HRTimeline
DAFNA Capital Management LLC8,600$793K0.18%-8,60013F-HRTimeline
DIVERSIFIED TRUST CO8,432$778K0.01%+59213F-HRTimeline
Creative Planningin group Creative Planning8,171$754K<0.01%+5,00713F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…8,145$751K<0.01%-79113F-HRTimeline
Leonteq Securities AG7,939$732K0.04%+3,09813F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM7,860$725K<0.01%-43213F-HRTimeline
Entropy Technologies, LP7,624$703K0.04%new13F-HRTimeline
HighTower Advisors, LLC7,543$696K<0.01%new13F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC7,329$692K0.01%-1,15913F-HRTimeline
Oak Thistle LLC7,293$673K0.09%new13F-HRTimeline
WORLDQUANT MILLENNIUM ADVISORS LLC7,204$664K<0.01%new13F-HRTimeline
SECTORAL ASSET MANAGEMENT INC7,200$664K0.53%new13F-HRTimeline
Everhart Financial Group, Inc.7,013$647K0.06%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC6,822$629K<0.01%-16,32213F-HRTimelineGroup
Marex Group Ltdin group Marex Group Ltd6,550$604K0.01%-1,90113F-HRTimelineGroup
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…6,546$604K<0.01%-30813F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC6,220$574K0.01%-2,28113F-HRTimeline
OREGON PUBLIC EMPLOYEES RETIREMENT FUND6,062$559K0.01%-1013F-HRTimeline
KLP KAPITALFORVALTNING AS6,000$553K<0.01%+40013F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC5,712$527K0.02%+1,63913F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC5,707$527K<0.01%-1,36913F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…5,712$527K<0.01%+73913F-HR/ATimelineGroup
Cetera Investment Advisers5,621$518K<0.01%new13F-HRTimeline
Counterpoint Mutual Funds LLC5,488$506K0.04%+1,26713F-HRTimeline
Mitsubishi UFJ Trust & Banking Corpgroup of 2 filers holding5,436$502K-54,165Timeline
Maryland State Retirement & Pension Sys…5,238$483K0.01%013F-HRTimeline
Sanctuary Advisors, LLC5,216$481K<0.01%new13F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC4,893$451K<0.01%-90313F-HRTimeline
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…4,815$444K0.01%+1,64713F-HRTimelineGroup
PDT Partners, LLC4,800$443K0.03%new13F-HRTimeline
BLAIR WILLIAM & CO/IL4,732$436K<0.01%-13313F-HRTimeline
M&T Bank Corpin group M&T Bank Corp4,708$434K<0.01%new13F-HR/ATimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN4,706$434K<0.01%-5,61213F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC4,665$430K<0.01%new13F-HRTimelineGroup
CHOREO, LLC4,463$413K0.01%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…4,476$413K<0.01%013F-HRTimelineGroup
Vestmark Advisory Solutions, Inc.4,438$409K0.01%new13F-HRTimeline
Janney Montgomery Scott LLC4,376$404K<0.01%new13F-HRTimeline
PharVision Advisers, LLC4,358$402K0.2%new13F-HRTimeline
Caitong International Asset Management …4,233$390K0.1%+3,15313F-HR/ATimeline
XPONANCE LLC4,143$382K<0.01%-3413F-HRTimeline