JW Asset Management, LLC More: the full row for JW Asset Management, LLC 3,092,485 $142M 67.72% -100,000 13F-HR Timeline RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 2,569,687 $118M 1.79% -76,016 13F-HR Timeline BROWN ADVISORY INC in group BROWN ADVISORY INC More: the full row for BROWN ADVISORY INC 2,338,369 $108M 0.14% +438,057 13F-HR Timeline Group Capital Research Global Investors in group Capital Research Global Inves… More: the full row for Capital Research Global Investors 1,911,525 $88.1M 0.02% +433,484 13F-HR Timeline Group Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 1,654,470 $76.2M 5.33% -704,671 13F-HR Timeline Group FINDELL CAPITAL MANAGEMENT LLC More: the full row for FINDELL CAPITAL MANAGEMENT LLC 1,346,480 $62M 28.34% +318,380 13F-HR Timeline SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT… in group SUMMIT PARTNERS PUBLIC ASSET … More: the full row for SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1,014,910 $46.8M 1.57% +543,801 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 821,125 $37.8M <0.01% +120,368 13F-HR/A Timeline Group WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC More: the full row for WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 812,825 $37.4M 0.09% +248,888 13F-HR Timeline RICE HALL JAMES & ASSOCIATES, LLC More: the full row for RICE HALL JAMES & ASSOCIATES, LLC 770,667 $35.5M 1.95% -22,633 13F-HR Timeline BAMCO INC /NY/ in group Baron Capital More: the full row for BAMCO INC /NY/ 752,886 $34.7M 0.09% +263,500 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 711,691 $32.8M 0.03% +450,213 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 558,289 $25.7M 0.06% +78,123 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 554,061 $25.5M <0.01% -349,354 13F-HR Timeline Group Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 546,519 $25.2M 0.14% 0 13F-HR Timeline Group TORONTO DOMINION BANK in group TORONTO DOMINION BANK More: the full row for TORONTO DOMINION BANK 540,024 $24.9M 0.05% new 13F-HR/A Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 525,248 $24.2M 0.74% +214,119 13F-HR Timeline Mudita Advisors LLP More: the full row for Mudita Advisors LLP 414,500 $19.1M 10.72% +59,699 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 408,262 $18.8M 0.02% +402,707 13F-HR/A Timeline Group Nuveen Asset Management, LLC in group TIAA More: the full row for Nuveen Asset Management, LLC 361,515 $16.7M <0.01% +42,413 13F-HR Timeline Group Redmile Group, LLC in group Redmile Group, LLC More: the full row for Redmile Group, LLC 320,149 $14.7M 1.03% +58,346 13F-HR Timeline Group Altium Capital Management LLC More: the full row for Altium Capital Management LLC 305,000 $14.1M 4.38% +174,000 13F-HR Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 300,000 $13.8M 0.82% +260,000 13F-HR Timeline Assenagon Asset Management S.A. More: the full row for Assenagon Asset Management S.A. 279,972 $12.9M 0.02% new 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 279,445 $12.9M 2.01% -11,002 13F-HR Timeline KORNITZER CAPITAL MANAGEMENT INC /KS More: the full row for KORNITZER CAPITAL MANAGEMENT INC /KS 246,235 $11.3M 0.22% -2,200 13F-HR Timeline Portolan Capital Management, LLC in group Portolan Capital Management, … More: the full row for Portolan Capital Management, LLC 193,991 $8.94M 0.6% +137,458 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 181,749 $8.37M +134,426 Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 165,677 $7.63M 0.02% +78,906 13F-HR Timeline Union Square Park Capital Management, L… More: the full row for Union Square Park Capital Management, LLC 160,000 $7.37M 8.03% +51,192 13F-HR Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 157,618 $7.26M 0.01% new 13F-HR Timeline Group Divisadero Street Capital Management, LP in group Divisadero Street Capital Man… More: the full row for Divisadero Street Capital Management, LP 150,772 $6.95M 0.87% -190,367 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 139,850 $6.44M <0.01% +31,060 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 133,088 $6.13M <0.01% -16,217 13F-HR Timeline Group RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 119,261 $5.49M <0.01% 13F-HR/A Timeline Group PURA VIDA INVESTMENTS, LLC More: the full row for PURA VIDA INVESTMENTS, LLC 113,041 $5.21M 28.8% -78,898 13F-HR Timeline ROYCE & ASSOCIATES LP More: the full row for ROYCE & ASSOCIATES LP 105,526 $4.86M 0.05% new 13F-HR Timeline Sofinnova Investments, Inc. More: the full row for Sofinnova Investments, Inc. 95,305 $4.39M 0.32% -86,171 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 91,652 $4.22M <0.01% -6,241 13F-HR Timeline Group 4D Advisors, LLC More: the full row for 4D Advisors, LLC 85,000 $3.92M 2.75% 13F-HR Timeline Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 80,002 $3.69M 2.98% +5,002 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 78,823 $3.63M <0.01% +81 13F-HR Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 70,645 $3.25M 0.01% -9,656 13F-HR Timeline Group Simplify Asset Management Inc. More: the full row for Simplify Asset Management Inc. 64,300 $2.96M 0.21% +42,661 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 59,400 $2.74M 0.21% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 50,660 $2.33M <0.01% +2,603 13F-HR Timeline Group NorthRock Partners, LLC More: the full row for NorthRock Partners, LLC 42,931 $1.98M 0.06% -2,345 13F-HR/A Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 42,471 $1.96M <0.01% +7,731 13F-HR Timeline Group Swiss National Bank More: the full row for Swiss National Bank 38,500 $1.77M <0.01% +1,000 13F-HR Timeline Magnetar Financial LLC in group Magnetar Financial LLC More: the full row for Magnetar Financial LLC 37,785 $1.74M 0.04% +148 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 35,817 $1.65M <0.01% +88 13F-HR Timeline Group Diametric Capital, LP More: the full row for Diametric Capital, LP 33,377 $1.54M 1.04% -573 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 32,720 $1.51M <0.01% +953 13F-HR Timeline Group BigSur Wealth Management LLC More: the full row for BigSur Wealth Management LLC 31,982 $1.47M 0.42% 0 13F-HR Timeline Strategic Wealth Partners, Ltd. More: the full row for Strategic Wealth Partners, Ltd. 40,683 $1.37M 0.11% new 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 28,165 $1.3M <0.01% +9,865 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 25,596 $1.18M <0.01% +240 13F-HR Timeline Group CI INVESTMENTS INC. in group CI INVESTMENTS INC. More: the full row for CI INVESTMENTS INC. 25,000 $1.15M <0.01% +15,000 13F-HR Timeline Group STABLEFORD CAPITAL II LLC More: the full row for STABLEFORD CAPITAL II LLC 24,814 $1.14M 0.45% -330 13F-HR Timeline LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 23,037 $1.06M 0.02% +13,037 13F-HR Timeline Group SIT INVESTMENT ASSOCIATES INC in group SIT INVESTMENT ASSOCIATES INC More: the full row for SIT INVESTMENT ASSOCIATES INC 21,600 $995K 0.02% +11,050 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 19,548 $901K <0.01% +836 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 16,860 $777K <0.01% +45 13F-HR/A Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 15,473 $713K <0.01% -45,889 13F-HR Timeline Group SkyView Investment Advisors, LLC More: the full row for SkyView Investment Advisors, LLC 14,700 $677K 0.11% +2,700 13F-HR Timeline Black Swift Group, LLC More: the full row for Black Swift Group, LLC 14,300 $659K 0.14% +7,100 13F-HR Timeline Exome Asset Management LLC More: the full row for Exome Asset Management LLC 13,100 $604K 0.45% -8,600 13F-HR Timeline PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 11,283 $520K 0.04% -1,081 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 10,934 $504K 0.01% +6,934 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 10,224 $471K <0.01% 0 13F-HR Timeline HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 9,828 $453K <0.01% -483 13F-HR Timeline Nebula Research & Development LLC More: the full row for Nebula Research & Development LLC 9,556 $440K 0.05% new 13F-HR Timeline Caption Management, LLC More: the full row for Caption Management, LLC 9,491 $437K 0.02% new 13F-HR Timeline Legato Capital Management LLC More: the full row for Legato Capital Management LLC 8,892 $410K 0.05% 0 13F-HR Timeline JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 8,376 $386K <0.01% 0 13F-HR Timeline Group Handelsbanken Fonder AB More: the full row for Handelsbanken Fonder AB 8,200 $378K <0.01% +2,000 13F-HR Timeline Q Fund Management (Hong Kong) Ltd More: the full row for Q Fund Management (Hong Kong) Ltd 6,000 $276K 0.29% 13F-HR Timeline Hood River Capital Management LLC More: the full row for Hood River Capital Management LLC 5,920 $273K <0.01% +4,160 13F-HR Timeline ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 5,660 $261K <0.01% +113 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 5,068 $233K <0.01% -189 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 4,151 $191K <0.01% -27,320 13F-HR/A Timeline Group KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 3,500 $161K <0.01% 13F-HR Timeline Twin Lakes Capital Management, LLC More: the full row for Twin Lakes Capital Management, LLC 2,931 $135K 0.09% 0 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 2,746 $127K <0.01% 0 13F-HR Timeline CIBC Private Wealth Group LLC in group CIBC Bancorp USA Inc. More: the full row for CIBC Private Wealth Group LLC 2,180 $103K <0.01% +194 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 2,000 $92.1K <0.01% 0 13F-HR Timeline Group MV CAPITAL MANAGEMENT, INC. More: the full row for MV CAPITAL MANAGEMENT, INC. 2,000 $92.1K 0.01% 0 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 1,317 $60.7K <0.01% 0 13F-HR/A Timeline Group SHELL ASSET MANAGEMENT CO More: the full row for SHELL ASSET MANAGEMENT CO 1,184 $55K <0.01% 0 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 992 $45.7K <0.01% +914 13F-HR Timeline Group Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 884 $40.7K <0.01% new 13F-HR Timeline Group R Squared Ltd More: the full row for R Squared Ltd 790 $36.4K 0.04% 13F-HR Timeline BESSEMER GROUP INC in group BESSEMER GROUP INC More: the full row for BESSEMER GROUP INC 742 $34K <0.01% -2,321 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 682 $31.4K <0.01% 0 13F-HR/A Timeline Quarry LP More: the full row for Quarry LP 591 $27.2K 0.01% new 13F-HR Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 492 $22.7K <0.01% new 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 473 $21.8K <0.01% -1,402 13F-HR Timeline Group GPS Wealth Strategies Group, LLC More: the full row for GPS Wealth Strategies Group, LLC 370 $17K <0.01% 0 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 347 $16K <0.01% +6 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 270 $12.4K <0.01% new 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 183 $8.43K <0.01% -44 13F-HR/A Timeline Group TOTH FINANCIAL ADVISORY CORP More: the full row for TOTH FINANCIAL ADVISORY CORP 135 $6.22K <0.01% 0 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 131 $6.04K <0.01% -10 13F-HR Timeline Geneos Wealth Management Inc. More: the full row for Geneos Wealth Management Inc. 129 $5.94K <0.01% +96 13F-HR Timeline QUADRANT CAPITAL GROUP LLC More: the full row for QUADRANT CAPITAL GROUP LLC 122 $5.62K <0.01% +73 13F-HR Timeline Clearstead Advisors, LLC More: the full row for Clearstead Advisors, LLC 119 $5.48K <0.01% +49 13F-HR Timeline HARBOUR INVESTMENTS, INC. More: the full row for HARBOUR INVESTMENTS, INC. 89 $4.1K <0.01% new 13F-HR Timeline NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 75 $3.46K <0.01% new 13F-HR Timeline Brooklyn Investment Group More: the full row for Brooklyn Investment Group 57 $2.63K <0.01% new 13F-HR Timeline Smartleaf Asset Management LLC More: the full row for Smartleaf Asset Management LLC 43 $1.95K <0.01% 0 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 40 $1.84K <0.01% 0 13F-HR Timeline Group Wilmington Savings Fund Society, FSB More: the full row for Wilmington Savings Fund Society, FSB 33 $1.52K <0.01% +8 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 21 $967 <0.01% 0 13F-HR Timeline Group Lindbrook Capital, LLC More: the full row for Lindbrook Capital, LLC 21 $967 <0.01% 0 13F-HR Timeline WOLFF WIESE MAGANA LLC More: the full row for WOLFF WIESE MAGANA LLC 15 $692 <0.01% 0 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 13 $599 <0.01% 0 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 10 $461 <0.01% +2 13F-HR Timeline Group Provenance Wealth Advisors, LLC More: the full row for Provenance Wealth Advisors, LLC 10 $461 <0.01% 0 13F-HR Timeline Amundi in group Amundi More: the full row for Amundi 7 $331 <0.01% new 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 5 $230 <0.01% 13F-HR/A Timeline NATIONAL BANK OF CANADA /FI/ in group NATIONAL BANK OF CANADA /FI/ More: the full row for NATIONAL BANK OF CANADA /FI/ 2 $92 <0.01% new 13F-HR Timeline Group IFP Advisors, Inc More: the full row for IFP Advisors, Inc 0 $92 <0.01% new 13F-HR Timeline Amount filed as zero, left out of ratios. CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0% 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.