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DAFNA Capital Management LLC

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13F filer, CIK 1389933, LOS ANGELES, CA

DAFNA Capital Management LLC reported $404,785,884 across 75 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 57.09% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001389933-25-000008

Period
2025-09-30
Reported value
$405M
Holdings
75
Top 10 weight
57.09%
New
7
Sold out
8

Largest buys vs the previous quarter

SecurityShares changeApprox. value
SLNOnew+53,000$3.58M
NKTRadded+44,998$2.56M
RAPPnew+75,000$2.23M
LRMRadded+656,330$2.12M
AQSTadded+370,589$2.07M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
BLUEPRINT MEDICINES CORPexited-168,763-$21.6M
MERUS N Vreduced-178,353-$16.8M
MLYSreduced-288,033-$10.9M
ASNDreduced-39,500-$7.85M
STOKreduced-332,181-$7.81M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001389933-25-000008, largest first. % of portfolio is the value over $404,785,884, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
STXSSTEREOTAXIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 13,680,554 shares; 2024Q4: 13,680,554 shares; 2025Q1: 13,680,554 shares; 2025Q2: 13,680,554 shares; 2025Q3: 13,680,554 shares 13,680,554$42.5M10.51%0Timeline
XBISPDR SERIES TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 401,505 shares; 2024Q4: 397,505 shares; 2025Q1: 404,505 shares; 2025Q2: 415,505 shares; 2025Q3: 401,505 shares 401,505$40.2M9.94%-14,000Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 517,994 shares; 2024Q4: 631,176 shares; 2025Q1: 656,176 shares; 2025Q2: 677,176 shares; 2025Q3: 657,176 shares 657,176$30.7M7.58%-20,000Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 398,100 shares; 2024Q4: 398,100 shares; 2025Q1: 398,100 shares; 2025Q2: 398,100 shares; 2025Q3: 394,940 shares 394,940$21.7M5.36%-3,160Timeline
ATRCATRICURE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 641,673 shares; 2024Q4: 641,673 shares; 2025Q1: 592,273 shares; 2025Q2: 592,273 shares; 2025Q3: 592,273 shares 592,273$20.9M5.16%0Timeline
MERUS N VMERUS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 412,573 shares; 2024Q4: 451,804 shares; 2025Q1: 461,804 shares; 2025Q2: 398,804 shares; 2025Q3: 220,451 shares 220,451$20.8M5.13%-178,353
IBBISHARES TRQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 102,500 shares; 2024Q4: 102,500 shares; 2025Q1: 102,500 shares; 2025Q2: 102,500 shares; 2025Q3: 102,500 shares 102,500$14.8M3.66%0Timeline
IDYAIDEAYA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 471,410 shares; 2024Q4: 498,827 shares; 2025Q1: 589,330 shares; 2025Q2: 619,090 shares; 2025Q3: 539,923 shares 539,923$14.7M3.63%-79,167Timeline
AXGNAXOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 935,894 shares; 2024Q4: 846,882 shares; 2025Q1: 680,782 shares; 2025Q2: 741,782 shares; 2025Q3: 742,282 shares 742,282$13.2M3.27%+500Timeline
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 273,739 shares; 2024Q4: 273,739 shares; 2025Q1: 273,739 shares; 2025Q2: 287,939 shares; 2025Q3: 287,939 shares 287,939$11.6M2.86%0Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 69,615 shares; 2024Q4: 71,615 shares; 2025Q1: 71,615 shares; 2025Q2: 70,615 shares; 2025Q3: 70,615 shares 70,615$9.91M2.45%0Timeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 256,717 shares; 2024Q4: 254,217 shares; 2025Q1: 625,126 shares; 2025Q2: 627,626 shares; 2025Q3: 627,626 shares 627,626$8.54M2.11%0Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 526,702 shares; 2024Q4: 542,002 shares; 2025Q1: 544,502 shares; 2025Q2: 543,602 shares; 2025Q3: 500,702 shares 500,702$7.7M1.9%-42,900Timeline
DAWNDAY ONE BIOPHARMACEUTICALS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 750,363 shares; 2024Q4: 731,363 shares; 2025Q1: 731,363 shares; 2025Q2: 879,163 shares; 2025Q3: 999,163 shares 999,163$7.04M1.74%+120,000Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 89,572 shares; 2024Q4: 103,355 shares; 2025Q1: 80,398 shares; 2025Q2: 72,677 shares; 2025Q3: 33,177 shares 33,177$6.6M1.63%-39,500Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 723,678 shares; 2024Q4: 811,678 shares; 2025Q1: 752,359 shares; 2025Q2: 581,757 shares; 2025Q3: 422,731 shares 422,731$5.15M1.27%-159,026Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 105,500 shares; 2025Q1: 212,001 shares; 2025Q2: 317,001 shares; 2025Q3: 317,001 shares 317,001$5.01M1.24%0Timeline
INGNINOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 208,790 shares; 2024Q4: 208,790 shares; 2025Q1: 458,065 shares; 2025Q2: 605,625 shares; 2025Q3: 605,625 shares 605,625$4.95M1.22%0Timeline
CMPSCOMPASS PATHWAYS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 243,210 shares; 2024Q4: 243,210 shares; 2025Q1: 711,046 shares; 2025Q2: 811,046 shares; 2025Q3: 811,046 shares 811,046$4.65M1.15%0Timeline
LKFTLAKEFRONT BIOTHERAPEUTICS NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 130,175 shares; 2024Q4: 130,175 shares; 2025Q1: 130,175 shares; 2025Q2: 130,175 shares; 2025Q3: 130,175 shares 130,175$4.51M1.11%0Timeline
DXCMDEXCOM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 65,552 shares; 2024Q4: 65,552 shares; 2025Q1: 65,552 shares; 2025Q2: 65,552 shares; 2025Q3: 65,552 shares 65,552$4.41M1.09%0Timeline
TNDMTANDEM DIABETES CARE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 204,208 shares; 2024Q4: 223,208 shares; 2025Q1: 294,208 shares; 2025Q2: 294,208 shares; 2025Q3: 355,208 shares 355,208$4.31M1.07%+61,000Timeline
KURAKURA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 408,368 shares; 2024Q4: 448,368 shares; 2025Q1: 463,368 shares; 2025Q2: 463,368 shares; 2025Q3: 463,368 shares 463,368$4.1M1.01%0Timeline
ALKSALKERMES PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 120,700 shares; 2024Q4: 120,700 shares; 2025Q1: 94,200 shares; 2025Q2: 103,748 shares; 2025Q3: 134,748 shares 134,748$4.04M1%+31,000Timeline
STOKSTOKE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 207,427 shares; 2024Q4: 171,097 shares; 2025Q1: 443,998 shares; 2025Q2: 501,972 shares; 2025Q3: 169,791 shares 169,791$3.99M0.99%-332,181Timeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 53,000 shares 53,000$3.58M0.89%newTimeline
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 187,130 shares; 2024Q4: 220,235 shares; 2025Q1: 220,235 shares; 2025Q2: 235,235 shares; 2025Q3: 235,235 shares 235,235$3.53M0.87%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 227,906 shares; 2024Q4: 187,140 shares; 2025Q1: 183,140 shares; 2025Q2: 238,140 shares; 2025Q3: 213,736 shares 213,736$3.47M0.86%-24,404Timeline
PRQRPROQR THRAPEUTICS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 905,582 shares; 2024Q4: 1,567,561 shares; 2025Q1: 1,567,561 shares; 2025Q2: 1,567,561 shares; 2025Q3: 1,567,561 shares 1,567,561$3.34M0.82%0Timeline
LRMRLARIMAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 494,274 shares; 2024Q4: 371,434 shares; 2025Q1: 371,434 shares; 2025Q2: 371,434 shares; 2025Q3: 1,027,764 shares 1,027,764$3.32M0.82%+656,330Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 116,882 shares; 2024Q4: 158,394 shares; 2025Q1: not reported; 2025Q2: 526,660 shares; 2025Q3: 946,661 shares 946,661$3.31M0.82%+420,001Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 146,500 shares; 2024Q4: 146,500 shares; 2025Q1: 309,200 shares; 2025Q2: 371,523 shares; 2025Q3: 83,490 shares 83,490$3.17M0.78%-288,033Timeline
NKTRNEKTAR THERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 10,000 shares; 2025Q3: 54,998 shares 54,998$3.13M0.77%+44,998Timeline
IMVTIMMUNOVANT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 51,996 shares; 2024Q4: 107,996 shares; 2025Q1: 169,996 shares; 2025Q2: 191,493 shares; 2025Q3: 191,493 shares 191,493$3.09M0.76%0Timeline
KRROKORRO BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 47,086 shares; 2025Q2: 57,691 shares; 2025Q3: 60,804 shares 60,804$2.91M0.72%+3,113Timeline
AQSTAQUESTIVE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 589,561 shares; 2024Q4: 127,000 shares; 2025Q1: 142,000 shares; 2025Q2: 142,000 shares; 2025Q3: 512,589 shares 512,589$2.87M0.71%+370,589Timeline
DNLIDENALI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 127,900 shares; 2025Q2: 168,500 shares; 2025Q3: 168,500 shares 168,500$2.45M0.6%0Timeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 250,583 shares; 2024Q4: 393,083 shares; 2025Q1: 378,083 shares; 2025Q2: 378,083 shares; 2025Q3: 358,083 shares 358,083$2.38M0.59%-20,000Timeline
ALECALECTOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 912,928 shares; 2024Q4: 912,928 shares; 2025Q1: 912,928 shares; 2025Q2: 912,928 shares; 2025Q3: 798,351 shares 798,351$2.36M0.58%-114,577Timeline
ASTRIA THERAPEUTICS INCASTRIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 254,165 shares; 2024Q4: 299,775 shares; 2025Q1: 314,775 shares; 2025Q2: 324,775 shares; 2025Q3: 319,775 shares 319,775$2.33M0.58%-5,000
RAPPRAPPORT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 75,000 shares 75,000$2.23M0.55%newTimeline
TELATELA BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,441,029 shares; 2025Q1: 1,441,029 shares; 2025Q2: 1,441,029 shares; 2025Q3: 1,441,029 shares 1,441,029$2.15M0.53%0Timeline
PODDINSULET CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 15,900 shares; 2024Q4: 12,400 shares; 2025Q1: 11,900 shares; 2025Q2: 9,900 shares; 2025Q3: 6,870 shares 6,870$2.12M0.52%-3,030Timeline
MDWDMEDIWOUND LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 64,479 shares; 2024Q4: 64,479 shares; 2025Q1: 64,479 shares; 2025Q2: 64,479 shares; 2025Q3: 113,612 shares 113,612$2.05M0.51%+49,133Timeline
ARAYACCURAY INC DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,222,358 shares; 2024Q4: 1,222,358 shares; 2025Q1: 1,222,358 shares; 2025Q2: 1,222,358 shares; 2025Q3: 1,222,358 shares 1,222,358$2.04M0.5%0Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 145,000 shares; 2024Q4: 245,000 shares; 2025Q1: 245,000 shares; 2025Q2: 245,000 shares; 2025Q3: 235,000 shares 235,000$2M0.49%-10,000Timeline
ALLOALLOGENE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,050,118 shares; 2024Q4: 1,240,118 shares; 2025Q1: 1,380,118 shares; 2025Q2: 1,380,118 shares; 2025Q3: 1,380,118 shares 1,380,118$1.71M0.42%0Timeline
VKTXVIKING THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 125,616 shares; 2024Q4: 64,516 shares; 2025Q1: 64,516 shares; 2025Q2: 64,516 shares; 2025Q3: 64,516 shares 64,516$1.7M0.42%0Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 667,000 shares; 2024Q4: 667,000 shares; 2025Q1: 558,255 shares; 2025Q2: 218,255 shares; 2025Q3: 218,255 shares 218,255$1.66M0.41%0Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 34,000 shares; 2024Q4: 35,500 shares; 2025Q1: 59,000 shares; 2025Q2: 59,000 shares; 2025Q3: 59,000 shares 59,000$1.65M0.41%0Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 85,000 shares 85,000$1.49M0.37%newTimeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 148,294 shares; 2024Q4: 88,790 shares; 2025Q1: 95,290 shares; 2025Q2: not reported; 2025Q3: 140,500 shares 140,500$1.41M0.35%newTimeline
ALGNALIGN TECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 5,500 shares; 2025Q1: 11,000 shares; 2025Q2: 11,000 shares; 2025Q3: 11,000 shares 11,000$1.38M0.34%0Timeline
KROSKEROS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 73,754 shares; 2024Q4: 130,316 shares; 2025Q1: 130,316 shares; 2025Q2: 130,316 shares; 2025Q3: 80,716 shares 80,716$1.28M0.32%-49,600Timeline
INSPINSPIRE MED SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 17,200 shares 17,200$1.28M0.32%newTimeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 242,000 shares; 2025Q2: 135,271 shares; 2025Q3: 104,671 shares 104,671$1.26M0.31%-30,600Timeline
BDTXBLACK DIAMOND THERAPEUTICS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 125,000 shares; 2024Q4: 140,000 shares; 2025Q1: 140,000 shares; 2025Q2: 471,000 shares; 2025Q3: 307,070 shares 307,070$1.16M0.29%-163,930Timeline
OBIOORCHESTRA BIOMED HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 363,636 shares 363,636$902K0.22%newTimeline
BWAYBRAINSWAY LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 251,346 shares; 2024Q4: 193,208 shares; 2025Q1: 156,533 shares; 2025Q2: 127,151 shares; 2025Q3: 56,966 shares 56,966$858K0.21%-70,185Timeline
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,704,232 shares; 2024Q4: 1,704,232 shares; 2025Q1: 1,704,232 shares; 2025Q2: 1,704,232 shares; 2025Q3: 1,704,232 shares 1,704,232$849K0.21%0Timeline
ERASERASCA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 340,000 shares; 2025Q2: 350,000 shares; 2025Q3: 350,000 shares 350,000$763K0.19%0Timeline
PYPDPOLYPID LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 308,497 shares; 2024Q4: 291,273 shares; 2025Q1: 291,273 shares; 2025Q2: 207,900 shares; 2025Q3: 207,900 shares 207,900$693K0.17%0Timeline
BNTXBIONTECH SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,500 shares; 2024Q4: 8,500 shares; 2025Q1: 10,500 shares; 2025Q2: 7,000 shares; 2025Q3: 7,000 shares 7,000$690K0.17%0Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 24,518 shares 24,518$634K0.16%newTimeline
FHTXFOGHORN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 37,664 shares; 2024Q4: 186,717 shares; 2025Q1: 304,752 shares; 2025Q2: 300,452 shares; 2025Q3: 126,859 shares 126,859$620K0.15%-173,593Timeline
URGNUROGEN PHARMA LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 458,915 shares; 2024Q4: 492,515 shares; 2025Q1: 492,515 shares; 2025Q2: 349,515 shares; 2025Q3: 27,515 shares 27,515$549K0.14%-322,000Timeline
NGNENEUROGENE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,775 shares; 2024Q4: 51,500 shares; 2025Q1: 51,500 shares; 2025Q2: 51,096 shares; 2025Q3: 30,375 shares 30,375$526K0.13%-20,721Timeline
BCYCBICYCLE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 122,200 shares; 2024Q4: 120,799 shares; 2025Q1: 80,799 shares; 2025Q2: 64,492 shares; 2025Q3: 64,492 shares 64,492$499K0.12%0Timeline
ADCTADC THERAPEUTICS SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 204,081 shares; 2024Q4: 224,081 shares; 2025Q1: 224,081 shares; 2025Q2: 122,081 shares; 2025Q3: 122,081 shares 122,081$488K0.12%0Timeline
CGENCOMPUGEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 447,202 shares; 2024Q4: 447,202 shares; 2025Q1: 272,402 shares; 2025Q2: 272,402 shares; 2025Q3: 272,402 shares 272,402$400K0.1%0Timeline
SUTRO BIOPHARMA INCSUTRO BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 329,579 shares; 2024Q4: 437,079 shares; 2025Q1: 437,079 shares; 2025Q2: 437,079 shares; 2025Q3: 437,079 shares 437,079$380K0.09%0
AUTLAUTOLUS THERAPEUTICS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 486,667 shares; 2024Q4: 586,667 shares; 2025Q1: 586,667 shares; 2025Q2: 425,616 shares; 2025Q3: 179,316 shares 179,316$292K0.07%-246,300Timeline
BIOMX INCBIOMX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 401,136 shares; 2024Q4: 401,136 shares; 2025Q1: 401,136 shares; 2025Q2: 401,136 shares; 2025Q3: 401,136 shares 401,136$211K0.05%0
APREAPREA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 137,174 shares; 2024Q4: 137,174 shares; 2025Q1: 137,174 shares; 2025Q2: 137,174 shares; 2025Q3: 137,174 shares 137,174$202K0.05%0Timeline

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
ASCENDIS PHARMA A/SASCENDIS PHARMA A/S Convertible bondprincipal4,000,000$5.44M0

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
BLUEPRINT MEDICINES CORPBLUEPRINT MEDICINES CORP168,763$21.6Mshares
ITEOS THERAPEUTICS INCITEOS THERAPEUTICS INC140,847$1.4Mshares
VYNEVYNE THERAPEUTICS INC636,103$1.05Mshares
GOSSGOSSAMER BIO INC849,921$1.05Mshares
PVLAPALVELLA THERAPEUTICS INC NE43,348$977Kshares
ADICET BIO INCADICET BIO INC540,000$329Kshares
PRCTPROCEPT BIOROBOTICS CORP3,000$173Kshares
IFRXINFLARX NV200,000$158Kshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001389933-25-000008 base2025-11-14acceptance time not in the bulk data set