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DAFNA Capital Management LLC

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13F filer, CIK 1389933, LOS ANGELES, CA

DAFNA Capital Management LLC reported $362,250,156 across 76 holdings for the quarter ended 2025-06-30, in a 13F-HR filed 2025-08-14. Its ten largest share positions make up 55.78% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001389932-25-000011

Period
2025-06-30
Reported value
$362M
Holdings
76
Top 10 weight
55.78%
New
3
Sold out
10

Largest buys vs the previous quarter

SecurityShares changeApprox. value
BLUEPRINT MEDICINES CORPadded+16,500$2.11M
CMPXnew+526,660$1.37M
INGNadded+147,560$1.04M
BCAXadded+105,000$975K
DAWNadded+147,800$961K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
MERUS N Vreduced-63,000-$3.31M
BCRXreduced-340,000-$3.05M
2SEVENTY BIO INC COMMON STO…exited-429,252-$2.12M
URGNreduced-143,000-$1.96M
KALVreduced-170,602-$1.93M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2025

Share positions as resolved from 13F-HR 0001389932-25-000011, largest first. % of portfolio is the value over $362,250,156, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
XBISPDR SERIES TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 401,505 shares; 2024Q4: 397,505 shares; 2025Q1: 404,505 shares; 2025Q2: 415,505 shares 415,505$34.5M9.51%+11,000Timeline
STXSSTEREOTAXIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 13,680,554 shares; 2024Q4: 13,680,554 shares; 2025Q1: 13,680,554 shares; 2025Q2: 13,680,554 shares 13,680,554$29M8.01%0Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 517,994 shares; 2024Q4: 631,176 shares; 2025Q1: 656,176 shares; 2025Q2: 677,176 shares 677,176$24.9M6.88%+21,000Timeline
BLUEPRINT MEDICINES CORPBLUEPRINT MEDICINES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 121,763 shares; 2024Q4: 149,763 shares; 2025Q1: 152,263 shares; 2025Q2: 168,763 shares 168,763$21.6M5.97%+16,500
MERUS N VMERUS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 412,573 shares; 2024Q4: 451,804 shares; 2025Q1: 461,804 shares; 2025Q2: 398,804 shares 398,804$21M5.79%-63,000
ATRCATRICURE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 641,673 shares; 2024Q4: 641,673 shares; 2025Q1: 592,273 shares; 2025Q2: 592,273 shares 592,273$19.4M5.36%0Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 398,100 shares; 2024Q4: 398,100 shares; 2025Q1: 398,100 shares; 2025Q2: 398,100 shares 398,100$13.2M3.63%0Timeline
IDYAIDEAYA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 471,410 shares; 2024Q4: 498,827 shares; 2025Q1: 589,330 shares; 2025Q2: 619,090 shares 619,090$13M3.59%+29,760Timeline
IBBISHARES TRQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 102,500 shares; 2024Q4: 102,500 shares; 2025Q1: 102,500 shares; 2025Q2: 102,500 shares 102,500$13M3.58%0Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 89,572 shares; 2024Q4: 103,355 shares; 2025Q1: 80,398 shares; 2025Q2: 72,677 shares 72,677$12.5M3.46%-7,721Timeline
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 273,739 shares; 2024Q4: 273,739 shares; 2025Q1: 273,739 shares; 2025Q2: 287,939 shares 287,939$9.01M2.49%+14,200Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 69,615 shares; 2024Q4: 71,615 shares; 2025Q1: 71,615 shares; 2025Q2: 70,615 shares 70,615$8.88M2.45%-1,000Timeline
AXGNAXOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 935,894 shares; 2024Q4: 846,882 shares; 2025Q1: 680,782 shares; 2025Q2: 741,782 shares 741,782$8.05M2.22%+61,000Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 723,678 shares; 2024Q4: 811,678 shares; 2025Q1: 752,359 shares; 2025Q2: 581,757 shares 581,757$6.58M1.82%-170,602Timeline
DXCMDEXCOM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 65,552 shares; 2024Q4: 65,552 shares; 2025Q1: 65,552 shares; 2025Q2: 65,552 shares 65,552$5.72M1.58%0Timeline
DAWNDAY ONE BIOPHARMACEUTICALS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 750,363 shares; 2024Q4: 731,363 shares; 2025Q1: 731,363 shares; 2025Q2: 879,163 shares 879,163$5.71M1.58%+147,800Timeline
STOKSTOKE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 207,427 shares; 2024Q4: 171,097 shares; 2025Q1: 443,998 shares; 2025Q2: 501,972 shares 501,972$5.7M1.57%+57,974Timeline
TNDMTANDEM DIABETES CARE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 204,208 shares; 2024Q4: 223,208 shares; 2025Q1: 294,208 shares; 2025Q2: 294,208 shares 294,208$5.48M1.51%0Timeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 256,717 shares; 2024Q4: 254,217 shares; 2025Q1: 625,126 shares; 2025Q2: 627,626 shares 627,626$5.11M1.41%+2,500Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 526,702 shares; 2024Q4: 542,002 shares; 2025Q1: 544,502 shares; 2025Q2: 543,602 shares 543,602$5.09M1.41%-900Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 146,500 shares; 2024Q4: 146,500 shares; 2025Q1: 309,200 shares; 2025Q2: 371,523 shares 371,523$5.03M1.39%+62,323Timeline
URGNUROGEN PHARMA LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 458,915 shares; 2024Q4: 492,515 shares; 2025Q1: 492,515 shares; 2025Q2: 349,515 shares 349,515$4.79M1.32%-143,000Timeline
INGNINOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 208,790 shares; 2024Q4: 208,790 shares; 2025Q1: 458,065 shares; 2025Q2: 605,625 shares 605,625$4.26M1.18%+147,560Timeline
LKFTLAKEFRONT BIOTHERAPEUTICS NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 130,175 shares; 2024Q4: 130,175 shares; 2025Q1: 130,175 shares; 2025Q2: 130,175 shares 130,175$3.64M1.01%0Timeline
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 187,130 shares; 2024Q4: 220,235 shares; 2025Q1: 220,235 shares; 2025Q2: 235,235 shares 235,235$3.32M0.92%+15,000Timeline
PRQRPROQR THRAPEUTICS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 905,582 shares; 2024Q4: 1,567,561 shares; 2025Q1: 1,567,561 shares; 2025Q2: 1,567,561 shares 1,567,561$3.2M0.88%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 227,906 shares; 2024Q4: 187,140 shares; 2025Q1: 183,140 shares; 2025Q2: 238,140 shares 238,140$3.12M0.86%+55,000Timeline
PODDINSULET CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 15,900 shares; 2024Q4: 12,400 shares; 2025Q1: 11,900 shares; 2025Q2: 9,900 shares 9,900$3.11M0.86%-2,000Timeline
IMVTIMMUNOVANT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 51,996 shares; 2024Q4: 107,996 shares; 2025Q1: 169,996 shares; 2025Q2: 191,493 shares 191,493$3.06M0.85%+21,497Timeline
ALKSALKERMES PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 120,700 shares; 2024Q4: 120,700 shares; 2025Q1: 94,200 shares; 2025Q2: 103,748 shares 103,748$2.97M0.82%+9,548Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 105,500 shares; 2025Q1: 212,001 shares; 2025Q2: 317,001 shares 317,001$2.94M0.81%+105,000Timeline
TELATELA BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,441,029 shares; 2025Q1: 1,441,029 shares; 2025Q2: 1,441,029 shares 1,441,029$2.8M0.77%0Timeline
KURAKURA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 408,368 shares; 2024Q4: 448,368 shares; 2025Q1: 463,368 shares; 2025Q2: 463,368 shares 463,368$2.67M0.74%0Timeline
DNLIDENALI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 127,900 shares; 2025Q2: 168,500 shares 168,500$2.36M0.65%+40,600Timeline
CMPSCOMPASS PATHWAYS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 243,210 shares; 2024Q4: 243,210 shares; 2025Q1: 711,046 shares; 2025Q2: 811,046 shares 811,046$2.27M0.63%+100,000Timeline
ALGNALIGN TECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 5,500 shares; 2025Q1: 11,000 shares; 2025Q2: 11,000 shares 11,000$2.08M0.57%0Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 667,000 shares; 2024Q4: 667,000 shares; 2025Q1: 558,255 shares; 2025Q2: 218,255 shares 218,255$1.96M0.54%-340,000Timeline
ASTRIA THERAPEUTICS INCASTRIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 254,165 shares; 2024Q4: 299,775 shares; 2025Q1: 314,775 shares; 2025Q2: 324,775 shares 324,775$1.74M0.48%+10,000
KROSKEROS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 73,754 shares; 2024Q4: 130,316 shares; 2025Q1: 130,316 shares; 2025Q2: 130,316 shares 130,316$1.74M0.48%0Timeline
VKTXVIKING THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 125,616 shares; 2024Q4: 64,516 shares; 2025Q1: 64,516 shares; 2025Q2: 64,516 shares 64,516$1.71M0.47%0Timeline
ARAYACCURAY INC DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,222,358 shares; 2024Q4: 1,222,358 shares; 2025Q1: 1,222,358 shares; 2025Q2: 1,222,358 shares 1,222,358$1.67M0.46%0Timeline
BWAYBRAINSWAY LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 251,346 shares; 2024Q4: 193,208 shares; 2025Q1: 156,533 shares; 2025Q2: 127,151 shares 127,151$1.67M0.46%-29,382Timeline
ALLOALLOGENE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,050,118 shares; 2024Q4: 1,240,118 shares; 2025Q1: 1,380,118 shares; 2025Q2: 1,380,118 shares 1,380,118$1.56M0.43%0Timeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 250,583 shares; 2024Q4: 393,083 shares; 2025Q1: 378,083 shares; 2025Q2: 378,083 shares 378,083$1.52M0.42%0Timeline
FHTXFOGHORN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 37,664 shares; 2024Q4: 186,717 shares; 2025Q1: 304,752 shares; 2025Q2: 300,452 shares 300,452$1.41M0.39%-4,300Timeline
ITEOS THERAPEUTICS INCITEOS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 161,584 shares; 2024Q4: 188,347 shares; 2025Q1: 213,347 shares; 2025Q2: 140,847 shares 140,847$1.4M0.39%-72,500
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 242,000 shares; 2025Q2: 135,271 shares 135,271$1.37M0.38%-106,729Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 116,882 shares; 2024Q4: 158,394 shares; 2025Q1: not reported; 2025Q2: 526,660 shares 526,660$1.37M0.38%newTimeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 145,000 shares; 2024Q4: 245,000 shares; 2025Q1: 245,000 shares; 2025Q2: 245,000 shares 245,000$1.32M0.36%0Timeline
ALECALECTOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 912,928 shares; 2024Q4: 912,928 shares; 2025Q1: 912,928 shares; 2025Q2: 912,928 shares 912,928$1.28M0.35%0Timeline
MDWDMEDIWOUND LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 64,479 shares; 2024Q4: 64,479 shares; 2025Q1: 64,479 shares; 2025Q2: 64,479 shares 64,479$1.25M0.34%0Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 34,000 shares; 2024Q4: 35,500 shares; 2025Q1: 59,000 shares; 2025Q2: 59,000 shares 59,000$1.22M0.34%0Timeline
BDTXBLACK DIAMOND THERAPEUTICS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 125,000 shares; 2024Q4: 140,000 shares; 2025Q1: 140,000 shares; 2025Q2: 471,000 shares 471,000$1.17M0.32%+331,000Timeline
LRMRLARIMAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 494,274 shares; 2024Q4: 371,434 shares; 2025Q1: 371,434 shares; 2025Q2: 371,434 shares 371,434$1.07M0.3%0Timeline
VYNEVYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 636,103 shares; 2025Q2: 636,103 shares 636,103$1.05M0.29%0Timeline
GOSSGOSSAMER BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,419,262 shares; 2024Q4: 1,409,262 shares; 2025Q1: 907,854 shares; 2025Q2: 849,921 shares 849,921$1.05M0.29%-57,933Timeline
PVLAPALVELLA THERAPEUTICS INC NEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 71,452 shares; 2025Q1: 43,348 shares; 2025Q2: 43,348 shares 43,348$977K0.27%0Timeline
AUTLAUTOLUS THERAPEUTICS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 486,667 shares; 2024Q4: 586,667 shares; 2025Q1: 586,667 shares; 2025Q2: 425,616 shares 425,616$970K0.27%-161,051Timeline
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,704,232 shares; 2024Q4: 1,704,232 shares; 2025Q1: 1,704,232 shares; 2025Q2: 1,704,232 shares 1,704,232$952K0.26%0Timeline
NGNENEUROGENE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,775 shares; 2024Q4: 51,500 shares; 2025Q1: 51,500 shares; 2025Q2: 51,096 shares 51,096$764K0.21%-404Timeline
BNTXBIONTECH SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,500 shares; 2024Q4: 8,500 shares; 2025Q1: 10,500 shares; 2025Q2: 7,000 shares 7,000$745K0.21%-3,500Timeline
PYPDPOLYPID LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 308,497 shares; 2024Q4: 291,273 shares; 2025Q1: 291,273 shares; 2025Q2: 207,900 shares 207,900$734K0.2%-83,373Timeline
KRROKORRO BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 47,086 shares; 2025Q2: 57,691 shares 57,691$721K0.2%+10,605Timeline
CGENCOMPUGEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 447,202 shares; 2024Q4: 447,202 shares; 2025Q1: 272,402 shares; 2025Q2: 272,402 shares 272,402$485K0.13%0Timeline
AQSTAQUESTIVE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 589,561 shares; 2024Q4: 127,000 shares; 2025Q1: 142,000 shares; 2025Q2: 142,000 shares 142,000$470K0.13%0Timeline
BCYCBICYCLE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 122,200 shares; 2024Q4: 120,799 shares; 2025Q1: 80,799 shares; 2025Q2: 64,492 shares 64,492$448K0.12%-16,307Timeline
ERASERASCA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 340,000 shares; 2025Q2: 350,000 shares 350,000$444K0.12%+10,000Timeline
ADICET BIO INCADICET BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 600,000 shares; 2024Q4: 600,000 shares; 2025Q1: 600,000 shares; 2025Q2: 540,000 shares 540,000$329K0.09%-60,000
ADCTADC THERAPEUTICS SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 204,081 shares; 2024Q4: 224,081 shares; 2025Q1: 224,081 shares; 2025Q2: 122,081 shares 122,081$327K0.09%-102,000Timeline
SUTRO BIOPHARMA INCSUTRO BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 329,579 shares; 2024Q4: 437,079 shares; 2025Q1: 437,079 shares; 2025Q2: 437,079 shares 437,079$312K0.09%0
NKTRNEKTAR THERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 10,000 shares 10,000$258K0.07%newTimeline
APREAPREA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 137,174 shares; 2024Q4: 137,174 shares; 2025Q1: 137,174 shares; 2025Q2: 137,174 shares 137,174$232K0.06%0Timeline
BIOMX INCBIOMX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 401,136 shares; 2024Q4: 401,136 shares; 2025Q1: 401,136 shares; 2025Q2: 401,136 shares 401,136$181K0.05%0
PRCTPROCEPT BIOROBOTICS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 3,000 shares 3,000$173K0.05%newTimeline
IFRXINFLARX NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 450,000 shares; 2025Q2: 200,000 shares 200,000$158K0.04%-250,000Timeline

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
ASCENDIS PHARMA A/SASCENDIS PHARMA A/S Convertible bondprincipal4,000,000$5.01M0

Sold out in Q2 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
2SEVENTY BIO INC COMMON STO…2SEVENTY BIO INC COMMON STOCK429,252$2.12Mshares
REGULUS THERAPEUTICS INCREGULUS THERAPEUTICS INC847,176$1.48Mshares
SPRYARS PHARMACEUTICALS INC95,290$1.2Mshares
LCTXLINEAGE CELL THERAPEUTICS IN2,511,374$1.13Mshares
SAGE THERAPEUTICS INCSAGE THERAPEUTICS INC108,200$860Kshares
TSHATAYSHA GENE THERAPIES INC522,500$726Kshares
CRDFCARDIFF ONCOLOGY INC150,000$471Kshares
NEVRO CORPNEVRO CORP38,000$222Kshares
SPROSPERO THERAPEUTICS INC125,000$90Kshares
TNYATENAYA THERAPEUTICS INC47,319$27Kshares

How Q2 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001389932-25-000011 base2025-08-14acceptance time not in the bulk data set