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ADAR1 Capital Management, LLC

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13F filer, CIK 1940272, AUSTIN, TX

ADAR1 Capital Management, LLC reported $500,371,182 across 214 holdings for the quarter ended 2024-12-31, in a 13F-HR filed 2025-02-13. Its ten largest share positions make up 49.77% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001940272-25-000001

Period
2024-12-31
Reported value
$500M
Holdings
214
Top 10 weight
49.77%
New
53
Sold out
117

Stakes and trades reported after 2024-12-31

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

Largest buys vs the previous quarter

SecurityShares changeApprox. value
IKTnew+5,103,005$16.6M
ZLABadded+513,383$13.4M
BILadded+110,000$10.1M
ABVXadded+991,781$7.26M
AVRnew+1,052,968$5.88M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
RPRXreduced-1,046,703-$26.7M
CYTKreduced-496,973-$23.4M
BBIOreduced-769,613-$21.1M
ASNDreduced-90,000-$12.4M
IMVTreduced-344,229-$8.53M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Back to all 195 share positions

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
PTGXPROTAGONIST THERAPEUTICS INC COMcall132,000$5.1Mnew
XBISPDR SERIES TRUST S&P BIOTECHcall50,000$4.5Mnew
JNJJOHNSON & JOHNSON COMcall10,000$1.45Mnew
CAPRCAPRICOR THERAPEUTICS INC COMMON STOCKcall95,000$1.31Mnew
CYTKCYTOKINETICS INC COM NEWcall15,100$710K0
AKROAKERO THERAPEUTICS INC COMcall22,500$626K0
Applied Therapeutics IncApplied Therapeutics Inc Common Stockcall530,324$454K+124
BMRNBIOMARIN PHARMACEUTICAL INC COMcall5,000$329K0
TARSTARSUS PHARMACEUTICALS INC COMMON STOCKcall5,000$277K0
RGNXREGENXBIO INC COMcall17,800$138K0
PHATPHATHOM PHARMACEUTICALS INC COMMON STOCKcall10,100$82Knew
CRVSCORVUS PHARMACEUTICALS INC COMput15,000$80.2Knew
CRVSCORVUS PHARMACEUTICALS INC COMcall10,000$53.5Knew
AMLXAMYLYX PHARMACEUTICALS INC COMcall10,000$37.8K0
GOSSGOSSAMER BIO INC Stockcall19,898$18K-102

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
COHERUS ONCOLOGY INCCOHERUS ONCOLOGY INC BONDprincipal5,625,000$5.48Mnew
GOSSAMER BIO INCGOSSAMER BIO INC NOTE 5.000% 6/0principal8,000,000$4.36Mnew
BRIDGEBIO PHARMA INCBRIDGEBIO PHARMA INC Convertibleprincipal4,500,000$3.86Mnew
BRIDGEBIO PHARMA INCBRIDGEBIO PHARMA INC NOTE 2.500% 3/1principal2,000,000$2.1Mnew

Sold out in Q4 2024

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
SNDXSYNDAX PHARMACEUTICALS INC350,206$6.74Mshares
XBISPDR SERIES TRUST40,000$3.95Mput
QTTBQ32 BIO INC64,245$2.87Mshares
PIERIS PHARMACEUTICALS INCPIERIS PHARMACEUTICALS INC144,641$2.4Mshares
NVONOVO-NORDISK A S20,000$2.38Mput
SNDXSYNDAX PHARMACEUTICALS INC105,000$2.02Mcall
MCKMCKESSON CORP3,000$1.48Mcall
NVONOVO-NORDISK A S10,000$1.19Mcall
BNTXBIONTECH SE10,000$1.19Mshares
ENVVENO MEDICAL CORPORATIONENVVENO MEDICAL CORPORATION348,263$1.17Mshares
PCVXVAXCYTE INC10,097$1.15Mshares
NUVLNUVALENT INC10,442$1.07Mshares
AVADEL PHARMACEUTICALSAVADEL PHARMACEUTICALS80,900$1.06Mshares
BCAXBICARA THERAPEUTICS INC40,440$1.03Mshares
INTRA-CELLULAR THERAPIES INCINTRA-CELLULAR THERAPIES INC13,400$980Kshares
AGIOAGIOS PHARMACEUTICALS INC21,300$946Kshares
REVANCE THERAPEUTICS INCREVANCE THERAPEUTICS INC182,166$945Kshares
MIRMMIRUM PHARMACEUTICALS INC24,100$940Kshares
MCKMCKESSON CORP1,850$915Kshares
CGEMCULLINAN THERAPEUTICS INC54,358$910Kshares
TARSTARSUS PHARMACEUTICALS INC25,900$852Kshares
AVANGRID INCAVANGRID INC23,000$823Kshares
AMLXAMYLYX PHARMACEUTICALS INC220,906$716Kshares
POWERSCHOOL HOLDINGS INCPOWERSCHOOL HOLDINGS INC30,000$684Kshares
AURAAURA BIOSCIENCES INC73,663$656Kshares
OPCHOPTION CARE HEALTH INC20,000$626Kshares
KURAKURA ONCOLOGY INC30,000$586Kshares
TMT ACQUISITION CORPTMT ACQUISITION CORP50,000$562Kshares
MASIMASIMO CORP3,894$519Kshares
THTARGET HOSPITALITY CORP65,741$511Kshares
ARVNARVINAS INC20,400$502Kshares
EWTXEDGEWISE THERAPEUTICS INC18,178$485Kshares
BLUEPRINT MEDICINES CORPBLUEPRINT MEDICINES CORP5,100$472Kshares
BIOMX INCBIOMX INC432,700$441Kshares
SYRESPYRE THERAPEUTICS INC12,560$369Kshares
ACADACADIA PHARMACEUTICALS INC23,100$355Kshares
TXG10X GENOMICS INC15,000$339Kshares
OAK WOODS ACQUISITION CORP-AOAK WOODS ACQUISITION CORP-A30,000$333Kshares
JSPRJASPER THERAPEUTICS INC15,816$297Kshares
IMVTIMMUNOVANT INC10,200$291Kcall
Tourmaline Bio IncTourmaline Bio Inc11,260$289Kshares
VYNEVYNE THERAPEUTICS INC152,865$287Kshares
ORKAORUKA THERAPEUTICS INC11,187$274Kshares
BSXBOSTON SCIENTIFIC CORP2,500$210Kshares
TERNTERNS PHARMACEUTICALS INC24,702$206Kshares
CLDXCELLDEX THERAPEUTICS INC NEW5,000$170Kshares
NUVEI CORPORATIONNUVEI CORPORATION5,000$167Kshares
ABEOABEONA THERAPEUTICS INC24,322$154Kshares
GALTGALECTIN THERAPEUTICS INC55,300$152Kput
PROPERTYGURU GROUP LTDPROPERTYGURU GROUP LTD20,000$132Kshares
BHVNBIOHAVEN LTD2,637$132Kshares
PERIMETER SOLUTIONS SAPERIMETER SOLUTIONS SA9,000$121Kshares
TGTXTG THERAPEUTICS INC5,000$117Kshares
BEYOND AIR INCBEYOND AIR INC282,131$109Kshares
ACRSACLARIS THERAPEUTICS INC90,000$104Kshares
ANIPANI PHARMACEUTICALS INC1,700$101Kshares
SYRSSYROS PHARMACEUTICALS INC COM45,000$96.8Kshares
LQDALIQUIDIA CORPORATION9,285$92.8Kshares
ESTAESTABLISHMENT LABS HLDGS INC2,000$86.5Kshares
BMRNBIOMARIN PHARMACEUTICAL INC1,200$84.3Kshares
CRBPCORBUS PHARMACEUTICALS HLDGS4,000$82.5Kshares
AI Transportation Acquisiti…AI Transportation Acquisition Corp7,500$78.6Kshares
IKENA ONCOLOGY INCIKENA ONCOLOGY INC44,635$77.2Kshares
Applied Therapeutics IncApplied Therapeutics Inc8,727$74.2Kshares
ITERIS INC NEWITERIS INC NEW10,000$71.4Kshares
SAGE THERAPEUTICS INCSAGE THERAPEUTICS INC9,500$68.6Kcall
FDMT4D MOLECULAR THERAPEUTICS IN6,000$64.9Kshares
CVSCVS HEALTH CORP1,000$62.9Kshares
PRTCYPURETECH HEALTH PLC3,000$61.8Kshares
GRALGRAIL INC4,401$60.6Kshares
WSTWEST PHARMACEUTICAL SVSC INC200$60Kshares
GLREGREENLIGHT CAP RE LTD4,385$59.9Kshares
ARGXARGENX SE110$59.6Kshares
TRIPTRIPADVISOR INC4,000$58Kshares
AZNASTRAZENECA PLC-SPONS ADR700$54.5Kshares
FULCFULCRUM THERAPEUTICS INC15,000$53.5Kcall
CARA THERAPEUTICS INCCARA THERAPEUTICS INC159,469$49.1Kshares
DIREXION SHS ETF TRDIREXION SHS ETF TR8,400$49.1Kshares
FIBROGEN INCFIBROGEN INC120,663$48.2Kshares
NORDSTROM INCNORDSTROM INC2,000$45Kshares
CELCCELCUITY INC3,000$44.7Kshares
MISTMILESTONE PHARMACEUTICALS IN27,931$42.5Kshares
UCTTULTRA CLEAN HLDGS INC1,000$39.9Kshares
LUMOS PHARMA INCLUMOS PHARMA INC10,000$38.7Kshares
PHVSPHARVARIS N V2,000$37Kshares
FBRXFORTE BIOSCIENCES INC6,000$33.5Kshares
IDYAIDEAYA BIOSCIENCES INC1,000$31.7Kshares
BHCBAUSCH HEALTH COS INC3,700$30.2Kshares
NATLNCR ATLEOS CORPORATION1,000$28.5Kshares
IONSIONIS PHARMACEUTICALS INC700$28Kshares
RNAMAVIDITY BIOSCIENCES INC600$27.6Kshares
VYXNCR VOYIX CORPORATION2,000$27.1Kshares
PRGOPERRIGO CO PLC1,000$26.2Kshares
TGTXTG THERAPEUTICS INC1,000$23.4Kput
NGNENEUROGENE INC553$23.2Kshares
KRYSKRYSTAL BIOTECH INC100$18.2Kshares
KROSKEROS THERAPEUTICS INC300$17.4Kcall
NTLAINTELLIA THERAPEUTICS INC800$16.4Kshares
EYPTEYEPOINT INC2,000$16Kshares
DYNDYNE THERAPEUTICS INC400$14.4Kshares
ENGNENGENE HOLDINGS INC1,970$13Kshares
BLCOBAUSCH PLUS LOMB CORP600$11.6Kshares
MDGLMADRIGAL PHARMACEUTICALS INC50$10.6Kshares
TMT ACQUISITION CORPTMT ACQUISITION CORP37,100$10.1Kshares
ADXNADDEX THERAPEUTICS LTD1,000$9.77Kshares
INTELLIGENT BIO SOLUTIONS ININTELLIGENT BIO SOLUTIONS IN5,389$9.32Kshares
OKLOOKLO INC1,000$8.09Kshares
MRKRMARKER THERAPEUTICS INC2,432$6.86Kshares
EQEQUILLIUM INC7,318$6.09Kshares
MRVIMARAVAI LIFESCIENCES HLDGS I700$5.82Kshares
BKHARBLACK HAWK ACQUISITION CORP3,000$3.48Kshares
ICHRICHOR HOLDINGS108$3.44Kshares
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INC100$3.2Kshares
MITKMITEK SYS INC200$1.73Kshares
AI TRANSPORTATION ACQUIS-RTSAI TRANSPORTATION ACQUIS-RTS7,500$1.27Kshares
ANROALTO NEUROSCIENCE INC100$1.14Kput
MKDWWMKDWELL TECH INC3,270$60shares

How Q4 2024 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001940272-25-000001 base2025-02-13acceptance time not in the bulk data set