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Disclosery

TMO THERMO FISHER SCIENTIFIC INC

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COM (common), issuer CIK 97745

2,530 managers (2,579 13F filers) reported a position in TMO shares at 2025-03-31, 337,991,197 shares in all. 126 filers opened a position and 159 filers sold out during the quarter.

Managers
2,530
13F filers
2,579
New
126
Added
1,043
Reduced
1,004
Sold out
159
Shares held by filers
337,991,197

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
VANGUARD GROUP INCgroup of 2 filers holding33,518,695$16.7B+233,276Timeline
BlackRock, Inc.in group BlackRock, Inc.29,080,121$14.5B0.31%+244,29013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP16,539,489$8.24B0.34%+91,46113F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY11,595,430$5.77B0.41%+105,14113F-HRTimelineGroup
Capital World Investors11,061,400$5.5B0.89%+1,631,28013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO10,137,780$5.04B0.38%+1,219,54613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/9,304,832$4.63B0.57%-1,611,79213F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC8,127,186$4.03B0.32%+269,80113F-HRTimelineGroup
Capital Research Global Investorsin group Capital Research Global Inves…7,612,797$3.79B0.82%-307,92913F-HRTimelineGroup
NORGES BANK6,187,594$3.08B0.43%+133,05313F-HR/ATimeline
Franklin Resourcesgroup of 2 filers holding6,062,173$3.02B+294,409Timeline
UBS Group AGgroup of 2 filers holding5,370,877$2.67B+519,257Timeline
FMR LLCin group FMR LLC4,642,545$2.31B0.15%-1,694,83213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/3,959,699$1.97B0.18%-86,47713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP3,882,819$1.93B0.29%-27,19613F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,224,676$1.6B0.36%-47,85513F-HR/ATimelineGroup
Charles Schwab Trust Cogroup of 2 filers holding2,925,502$1.46B+114,818Timeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…2,879,274$1.43B1.59%+193,37813F-HRTimelineGroup
Amundiin group Amundi3,029,044$1.43B0.52%+168,19713F-HRTimelineGroup
Fisher Asset Management, LLC2,715,418$1.35B0.58%+49,51613F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp2,528,996$1.26B0.25%-28,20113F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,416,117$1.2B0.23%+212,73213F-HR/ATimelineGroup
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…2,396,032$1.19B0.4%-179,59913F-HRTimelineGroup
POLEN CAPITAL MANAGEMENT LLC2,322,482$1.16B3.63%-138,71313F-HRTimeline
PRIMECAP MANAGEMENT CO/CA/2,317,302$1.15B0.95%-187,84913F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc2,278,818$1.13B0.31%+16,27813F-HRTimelineGroup
DZ BANK AG Deutsche Zentral Genossensch…in group DZ BANK AG Deutsche Zentral G…2,123,640$1.06B1.23%+588,49713F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC2,076,634$1.03B0.28%-154,39613F-HRTimelineGroup
Mitsubishi UFJ Trust & Banking Corpgroup of 3 filers holding1,993,418$992M+162,722Timeline
Unisphere Establishmentin group Unisphere Establishment1,950,000$970M8.47%+250,00013F-HRTimelineGroup
T. Rowe Price Investment Management, In…1,942,745$967M0.64%-1,141,15513F-HRTimeline
ALLIANCEBERNSTEIN L.P.1,766,067$879M0.32%+272,74713F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,729,682$861M0.21%-170,14113F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.1,688,214$840M0.16%+10,63313F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP1,643,783$818M0.83%-35,19713F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…1,595,715$794M0.15%+167,76313F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC1,557,847$775M1.19%+65,73213F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC1,495,603$744M0.34%+195,37013F-HR/ATimelineGroup
Natixis Investment Managersgroup of 4 filers holding1,463,097$728M+75,556Timeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN1,456,782$725M0.17%+14,32213F-HRTimelineGroup
Grantham, Mayo, Van Otterloo & Co. LLC1,456,080$725M2.28%+362,21413F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …1,449,997$722M0.68%-226,27013F-HRTimelineGroup
Alphinity Investment Management Pty Ltd1,440,877$717M4.86%+164,32413F-HRTimeline
PARNASSUS INVESTMENTS, LLC1,420,431$707M1.7%+9,47413F-HRTimeline
FLOSSBACH VON STORCH SE1,412,839$703M3.04%+77,55413F-HRTimeline
LOOMIS SAYLES & CO L Pin group LOOMIS SAYLES & CO L P1,346,980$670M0.97%+93,62713F-HRTimelineGroup
Veritas Asset Management LLP1,333,052$663M6.7%+305,89313F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,263,590$629M0.25%-58,04313F-HRTimelineGroup
Temasek Holdings (Private) Ltdin group Temasek Holdings (Private) Ltd1,258,117$626M2.53%+200,86913F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding1,238,036$616M+12,063Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,217,615$606M0.46%+171,10413F-HRTimelineGroup
GENERATION INVESTMENT MANAGEMENT LLP1,190,561$592M3.58%-381,17313F-HRTimeline
TIAAgroup of 3 filers holding1,182,092$588M+1,087,580Timeline
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …1,118,379$557M0.39%-63813F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson1,100,274$550M0.3%+53,40313F-HRTimelineGroup
Swiss National Bank1,078,700$537M0.38%-40013F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.1,042,360$519M1.89%+116,44313F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.1,035,856$515M2.78%-197,40013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S1,033,663$514M6.38%-43,29213F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC1,025,393$510M0.39%+241,08713F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC950,308$473M0.68%-47,86713F-HRTimelineGroup
FIRST MANHATTAN CO. LLC.948,563$472M1.38%+57,24213F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC937,470$465M0.31%-67,76513F-HRTimelineGroup
Corient Private Wealth LPgroup of 2 filers holding927,458$462M+31,531Timeline
Longview Partners (Guernsey) LTDin group Longview Partners (Guernsey) …914,185$455M3.66%-56,61913F-HRTimelineGroup
Cantillon Capital Management LLCin group Cantillon Capital Management …901,773$449M2.91%-28,09713F-HR/ATimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC884,159$440M0.37%-280,61313F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding860,461$428M-524,570Timeline
Alecta Tjanstepension Omsesidigt850,700$423M2.37%-430,80013F-HRTimeline
Allianz SEgroup of 2 filers holding847,627$422M+39,753Timeline
Rathbones Group PLC841,990$419M2.02%+45,67313F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCgroup of 2 filers holding832,815$414M-22,605Timeline
Robeco Institutional Asset Management B…group of 2 filers holding828,164$412M+57,507Timeline
National Pension Service796,154$396M0.38%+51,17513F-HRTimeline
1832 Asset Management L.P.788,775$392M0.75%+245,21213F-HRTimeline
California Public Employees Retirement …785,621$391M0.27%-17,58213F-HRTimeline
MACKENZIE FINANCIAL CORP785,388$391M0.56%-118,55013F-HRTimeline
Ensign Peak Advisors, Inc773,409$385M0.74%-287,53413F-HRTimeline
KING LUTHER CAPITAL MANAGEMENT CORP768,433$382M1.77%-11,37313F-HRTimeline
DekaBank Deutsche Girozentrale767,218$380M0.75%-5,42513F-HRTimeline
ROYAL LONDON ASSET MANAGEMENT LTD737,436$367M0.87%-21,49413F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC725,280$361M0.14%-1,13213F-HRTimelineGroup
Qube Research & Technologies Ltd716,690$357M0.55%+109,27013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP665,508$331M0.35%+8,41213F-HRTimelineGroup
Navera Investment Management Ltd.661,218$329M6.02%+29,36213F-HRTimeline
RHUMBLINE ADVISERS658,357$328M0.31%-6,25513F-HR/ATimeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …655,936$326M0.26%+286,65113F-HRTimelineGroup
Stockbridge Partners LLC647,309$322M7.13%+80,72613F-HRTimeline
Sustainable Growth Advisers, LP632,040$315M1.75%-80,16613F-HRTimeline
NorthCoast Asset Management LLC631,342$314M1.58%+154,72713F-HR/ATimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A630,639$314M1.18%+102,31413F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC625,614$311M0.56%-8,42513F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…599,769$298M0.37%-3,85313F-HRTimeline
W1M Investment Management Ltd594,729$296M4.58%+52,32413F-HRTimeline
B. Metzler seel. Sohn & Co. AGin group B. Metzler seel. Sohn & Co. AG591,068$294M3.03%+185,87013F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC585,525$291M0.32%-177,24513F-HR/ATimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/584,011$291M0.15%-100,65013F-HRTimelineGroup
Ninety One UK Ltd569,045$283M0.79%+61,65513F-HRTimeline
BlueSpruce Investments, LP563,046$280M6.54%-250,77513F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC540,786$269M0.38%-16,66313F-HRTimelineGroup
BROWN BROTHERS HARRIMAN & COin group BROWN BROTHERS HARRIMAN & CO523,257$260M1.82%-6,23713F-HRTimelineGroup
AXA S.A.in group AXA S.A.520,551$259M0.85%-127,87013F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND517,512$258M0.38%-24,44813F-HR/ATimeline
BAILLIE GIFFORD & COin group BAILLIE GIFFORD & CO509,377$253M0.22%-29,48013F-HRTimelineGroup
Lindsell Train Ltd508,790$253M7.01%+101,55013F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.601,755$252M0.53%-97413F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/497,048$247M0.29%+128,96913F-HRTimelineGroup
Liontrust Investment Partners LLP490,390$244M3.81%+1,69313F-HRTimeline
Bank Julius Baer & Co. Ltd, Zurich480,393$239M0.78%+37,56513F-HR/ATimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co476,962$238M0.42%-41,58813F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD466,622$232M0.23%-148,33913F-HRTimeline
FIL Ltdin group FIL Ltd462,152$230M0.22%+115,01313F-HRTimelineGroup
LORING WOLCOTT & COOLIDGE FIDUCIARY ADV…523,480$226M2.2%+71013F-HRTimeline
TD Asset Management Inc444,718$221M0.2%-41,48013F-HRTimeline
Candriam S.C.A.422,354$210M1.32%+14,86413F-HRTimeline
Harding Loevner LP416,581$207M1.59%-58,35913F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc415,557$205M0.4%+155,57613F-HRTimelineGroup
CI INVESTMENTS INC.in group CI INVESTMENTS INC.396,988$198M0.83%+21,34913F-HRTimelineGroup
Handelsbanken Fonder AB393,531$196M0.81%+19,31113F-HRTimeline
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP390,715$194M0.25%-27,65013F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …382,639$190M0.38%+7,71113F-HRTimelineGroup
OMERS ADMINISTRATION Corp382,534$190M1.67%-1,23313F-HRTimeline
Sarasin & Partners LLPin group Sarasin & Partners LLP376,074$187M2.03%new13F-HR/ATimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…366,897$183M0.36%+15013F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding365,311$182M+35,815Timeline
MANNING & NAPIER ADVISORS LLC363,111$181M2.23%+95,50913F-HRTimeline
APG Asset Management N.V.group of 2 filers holding390,090$180M+13,806Timeline
Capitolis Liquid Global Markets LLCin group CAPITOLIS LIQUID GLOBAL MARKE…359,600$179M1.58%-5,00013F-HRTimelineGroup
Local Pensions Partnership Investment L…357,305$178M3.53%013F-HRTimeline
Korea Investment CORP355,698$177M0.43%+26,96513F-HRTimeline
FIFTH THIRD BANK, NATIONAL ASSOCIATIONgroup of 2 filers holding354,418$176M+12,401Timeline
EdgePoint Investment Group Inc.345,938$172M1.39%new13F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…343,855$171M0.42%+55,02113F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC336,973$168M0.28%-15,00513F-HRTimelineGroup
Findlay Park Partners LLP333,820$166M1.71%+4,40013F-HRTimeline
AKO CAPITAL LLP332,845$166M2.15%+19,06113F-HRTimeline
Danica Pension, Livsforsikringsaktiesel…325,156$162M3.2%+151,52613F-HRTimeline
Cryder Capital Partners LLP324,801$162M12.1%013F-HRTimeline
VAN LANSCHOT KEMPEN INVESTMENT MANAGEME…321,514$160M1.67%+11,53913F-HRTimeline
NEW YORK STATE TEACHERS RETIREMENT SYST…318,800$159M0.37%-12,97613F-HRTimeline
KEYBANK NATIONAL ASSOCIATION/OHin group KEYBANK NATIONAL ASSOCIATION/…314,900$157M0.63%-12,77113F-HRTimelineGroup
DANSKE BANK A/S295,330$147M0.45%+46,51213F-HRTimeline
Evercore Wealth Management, LLC289,694$144M2.32%-8,38913F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …287,411$143M0.38%+70013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…286,567$143M0.2%-7,48213F-HRTimelineGroup
BRISTOL JOHN W & CO INC /NY/282,585$141M2.4%-6,01613F-HRTimeline
Perpetual Ltdin group Perpetual Ltd277,938$138M1.67%+47,97613F-HRTimelineGroup
LPL Financial LLC278,299$138M0.05%+15,86213F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…276,374$138M0.59%-44613F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…272,053$135M0.07%+1,59113F-HRTimelineGroup
AVIVA PLCin group AVIVA PLC268,213$133M0.32%+25,95113F-HRTimelineGroup
CCLA Investment Management267,186$133M2.35%+8,61513F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO258,437$129M0.17%+6,43513F-HR/ATimelineGroup
KBC Group NVin group KBC Group NV257,754$128M0.4%-46,04713F-HRTimelineGroup
Compagnie Lombard Odier SCmA250,267$125M1.53%+56,37113F-HRTimeline
BRADLEY FOSTER & SARGENT INC/CT243,390$121M2.07%+39,24813F-HRTimeline
Chevy Chase Trust Holdings, LLCin group Chevy Chase Trust Holdings, L…242,572$121M0.39%+22,36813F-HRTimelineGroup
Quilter Plcin group Quilter Plc240,128$119M2.48%+4,82413F-HRTimelineGroup
Skandinaviska Enskilda Banken AB (publ)236,919$118M0.58%+62,31213F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.235,371$117M0.14%-307,95513F-HRTimelineGroup
James Hambro & Partners LLP234,423$117M4.87%+12,21913F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…233,452$116M0.22%-156,86313F-HRTimelineGroup
Route One Investment Company, L.P.232,430$116M4.82%013F-HRTimeline
LBP AM SA230,201$115M1.77%+69,50713F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD229,094$114M0.29%+8,28213F-HRTimeline
CIBC Asset Management Inc227,420$113M0.38%-5,19013F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC226,777$113M0.23%+65,26213F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…226,478$113M0.32%+4,73113F-HRTimeline
Focus Partners Wealthgroup of 2 filers holding224,708$112M+751Timeline
Ownership Capital B.V.222,865$111M5.08%-41,53213F-HRTimeline
STOREBRAND ASSET MANAGEMENT AS221,981$110M0.36%-7,80013F-HRTimeline
Haverford Trust Co220,235$110M1.1%+11,27513F-HRTimeline
Milestone Resources Group Ltd219,464$109M5.78%013F-HRTimeline
Capital International Investorsgroup of 3 filers holding216,230$108M+54,135Timeline
Mondrian Investment Partners LTD214,506$107M1.83%+127,35713F-HRTimeline
COMMERCE BANKin group COMMERCE BANK213,750$106M0.68%-3,55213F-HRTimelineGroup
Baird Financial Group, Inc.in group Baird Financial Group, Inc.212,811$106M0.2%-97613F-HRTimelineGroup
DF DENT & CO INC212,499$106M1.41%-5,80513F-HRTimeline
Public Sector Pension Investment Board211,095$105M0.45%+1,29813F-HRTimeline
GREAT LAKES ADVISORS, LLC208,248$103M0.92%+4,58013F-HRTimeline
Retirement Systems of Alabama205,921$102M0.4%-2,03213F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC209,265$102M0.11%-11,93713F-HRTimelineGroup
Asset Management One Co., Ltd.199,057$99.1M0.34%+17,22813F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS198,211$98.6M0.45%-3,07013F-HRTimelineGroup
STRS OHIO197,951$98.5M0.41%-1,57113F-HRTimeline
AGF MANAGEMENT LTDin group AGF MANAGEMENT LTD196,727$97.9M0.52%+63,20113F-HRTimelineGroup
WORLDQUANT MILLENNIUM ADVISORS LLC191,481$95.3M0.6%-14,04813F-HRTimeline
Impax Asset Management Group plcin group Impax Asset Management Group …192,838$95M0.57%-431,25513F-HRTimelineGroup
Formuepleje A/S190,561$94.8M5.41%-9,16713F-HRTimeline
BARTLETT & CO. WEALTH MANAGEMENT LLC189,952$94.6M1.39%+9,98913F-HRTimeline
PGGM Investments189,875$94.5M1.27%-14,44713F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK189,245$94.2M0.24%-20,38613F-HRTimelineGroup
Carmignac Gestion189,172$94.2M1.55%+33,01913F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC188,475$93.8M0.09%-153,90613F-HRTimelineGroup
Douglas Lane & Associates, LLC187,198$93.1M1.37%+4,68713F-HRTimeline
Treasurer of the State of North Carolina186,994$93M0.37%+12,40813F-HRTimeline
HighTower Advisors, LLC179,384$89.3M0.12%+1,71413F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\177,933$88.5M0.12%-2,70913F-HRTimelineGroup
HM PAYSON & CO175,706$87.4M1.53%+8,90413F-HRTimeline
Evelyn Partners Group Ltdgroup of 3 filers holding174,112$86.6M+8,436Timeline