Skip to content
Disclosery

OBIO ORCHESTRA BIOMED HLDGS INC

Follow

COMMON STOCK (common), issuer CIK 1814114

52 managers (52 13F filers) reported a position in OBIO shares at 2025-09-30, 22,889,772 shares in all. 10 filers opened a position and 17 filers sold out during the quarter.

Managers
52
13F filers
52
New
10
Added
15
Reduced
17
Sold out
17
Shares held by filers
22,889,772

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RTW INVESTMENTS, LP8,306,063$20.6M0.25%+113F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC5,292,556$13.1M0.38%+700,00013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,481,875$3.68M<0.01%+324,55813F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.1,365,482$3.39M0.01%new13F-HRTimelineGroup
Pathstone Holdings, LLCin group Pathstone Holdings, LLC1,006,018$2.49M0.01%new13F-HRTimelineGroup
Affinity Asset Advisors, LLC727,272$1.8M0.17%new13F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.664,333$1.65M<0.01%-17,01613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/421,612$1.05M<0.01%-16,75713F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC386,799$960K<0.01%+84,71713F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC380,508$944K<0.01%+211,10813F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC373,987$927K<0.01%-35,68713F-HRTimelineGroup
DAFNA Capital Management LLC363,636$902K0.22%new13F-HRTimeline
Knott David M Jr195,000$484K0.2%+95,00013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co180,439$447K<0.01%+41,84813F-HRTimelineGroup
Knoll Capital Management, LLC455,128$421K0.23%013F-HRTimeline
AMH Equity Ltd166,000$412K0.52%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP102,572$254K<0.01%+2,13713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP100,733$250K<0.01%-29,40013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…98,105$243K<0.01%-20,45313F-HRTimelineGroup
TD Asset Management Inc92,678$230K<0.01%013F-HRTimeline
IFP Advisors, Inc86,698$215K0.01%+1,34013F-HR/ATimeline
Cubist Systematic Strategies, LLC77,892$193K<0.01%+60,17613F-HRTimeline
Holos Integrated Wealth LLC51,595$163K0.1%013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC65,524$162K<0.01%+47,01113F-HRTimelineGroup
LASRY MARC60,869$151K1%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC54,002$134K<0.01%+4,56113F-HRTimelineGroup
NewEdge Advisors, LLC44,083$109K<0.01%013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd34,818$86.3K<0.01%+18,00113F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …32,518$80.6K<0.01%013F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/31,119$77.2K<0.01%+9,54213F-HR/ATimelineGroup
Qube Research & Technologies Ltd25,934$64.3K<0.01%new13F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC25,000$62K<0.01%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC23,630$58.6K<0.01%-73,21113F-HRTimelineGroup
HighTower Advisors, LLC18,275$45.3K<0.01%-48,22513F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC17,112$42.4K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning17,101$42.4K<0.01%+2,10113F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd15,577$38.5K<0.01%new13F-HRTimelineGroup
ABLE Financial Group, LLC13,402$33.2K0.01%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY10,323$25.6K<0.01%-3,05913F-HR/ATimelineGroup
Point72 Asia (Singapore) Pte. Ltd.9,346$23.2K<0.01%-9,36413F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA6,363$16K<0.01%-1,46613F-HRTimelineGroup
UBS Group AGin group UBS Group AG3,815$9.46K<0.01%-22,32413F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.1,988$4.93K<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS564$1.4K<0.01%-1,84113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO470$1.17K<0.01%013F-HR/ATimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.312$774<0.01%new13F-HRTimelineGroup
Point72 (DIFC) Ltd272$675<0.01%-8213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC41$102<0.01%-7,62013F-HRTimelineGroup
SBI Securities Co., Ltd.6$15<0.01%-67513F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC1$2<0.01%-87313F-HR/ATimelineGroup
SIMPLEX TRADING, LLC324$00%new13F-HRTimelineValue filed as zero, left out of ratios.
CWM, LLCin group CWM, LLC2$00%-37913F-HRTimelineGroupValue filed as zero, left out of ratios.