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Disclosery

OBIO ORCHESTRA BIOMED HLDGS INC

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COMMON STOCK (common), issuer CIK 1814114

63 managers (65 13F filers) reported a position in OBIO shares at 2026-03-31, 23,094,646 shares in all. 16 filers opened a position and 16 filers sold out during the quarter.

Managers
63
13F filers
65
New
16
Added
23
Reduced
14
Sold out
16
Shares held by filers
23,094,646

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RTW INVESTMENTS, LP8,306,063$35.3M0.35%013F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC5,037,906$21.4M0.42%-89,35013F-HR/ATimelineGroup
VANGUARD GROUP INCgroup of 3 filers holding2,453,481$10.4MnewTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.1,000,000$4.25M0.01%013F-HRTimelineGroup
Propel Bio Management, LLC896,701$3.83M2.41%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC702,543$2.99M<0.01%+459,07013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.635,714$2.7M<0.01%+4,81313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC485,492$2.06M<0.01%+12,12913F-HRTimelineGroup
Affinity Asset Advisors, LLC402,550$1.71M0.1%-170,25413F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co265,499$1.13M<0.01%+1,71113F-HRTimelineGroup
Knott David M Jr253,651$1.08M0.64%+3,65113F-HRTimeline
Simplify Asset Management Inc.219,387$932K0.01%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP188,484$801K<0.01%+16,80313F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC185,000$786K0.07%-19,07613F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP169,410$720K<0.01%+10,37713F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC155,242$660K<0.01%+21,16913F-HRTimelineGroup
DAFNA Capital Management LLC126,841$539K0.12%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP118,274$503K<0.01%+7,37513F-HRTimelineGroup
Qube Research & Technologies Ltd108,953$463K<0.01%+2,21113F-HRTimeline
IFP Advisors, Inc98,887$420K0.01%+12,18913F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…97,521$414K<0.01%-57,60913F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.87,888$374K<0.01%-74,05813F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC79,185$337K<0.01%+49,01013F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…71,134$302K<0.01%+21,70913F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC70,900$301K<0.01%-80,40013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC70,600$300K0.01%+45,60013F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP60,107$255K<0.01%-26,44513F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC59,342$252K<0.01%-35,17513F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC55,680$237K<0.01%-118,08513F-HRTimelineGroup
Daytona Street Capital LLC52,600$235K0.18%+31,10013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/52,761$224K<0.01%+35,21413F-HRTimelineGroup
Holos Integrated Wealth LLC51,595$220K0.11%013F-HRTimeline
UBS Group AGin group UBS Group AG50,310$214K<0.01%+38,92113F-HRTimelineGroup
NewEdge Advisors, LLC44,083$187K<0.01%013F-HR/ATimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…36,769$156K<0.01%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY35,639$151K<0.01%-46,21213F-HRTimelineGroup
Meramec Financial Planners, LLC30,000$130K0.05%013F-HRTimeline
Catalyst Funds Management Pty Ltd27,644$117K0.02%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC25,529$108K<0.01%+6,07113F-HRTimelineGroup
Cannon Global Investment Management, LLC22,607$96.1K0.23%new13F-HRTimeline
RICE HALL JAMES & ASSOCIATES, LLC19,001$80.8K<0.01%new13F-HRTimeline
Diametric Capital, LP18,919$80.4K0.02%new13F-HRTimeline
HighTower Advisors, LLC18,275$77.7K<0.01%013F-HRTimeline
FMR LLCin group FMR LLC18,076$76.8K<0.01%new13F-HRTimelineGroup
OMERS ADMINISTRATION Corp16,200$68.8K<0.01%-50,90013F-HRTimeline
ALGERT GLOBAL LLC14,656$62.3K<0.01%new13F-HR/ATimeline
ABLE Financial Group, LLC13,402$57K0.01%013F-HRTimeline
Frec Markets, Inc.in group Frec Markets, Inc.13,048$55.5K0.01%new13F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC12,389$52.7K<0.01%new13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD11,300$48K<0.01%+4,20013F-HRTimeline
Schonfeld Strategic Advisors LLC10,953$46.5K<0.01%new13F-HRTimeline
Garden State Investment Advisory Servic…10,562$44.9K0.01%new13F-HRTimeline
China Universal Asset Management Co., L…10,020$42.6K<0.01%+81913F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO4,258$17.3K<0.01%-32813F-HR/ATimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…2,945$12.5K<0.01%+20113F-HR/ATimelineGroup
SIMPLEX TRADING, LLC2,381$10.1K<0.01%new13F-HRTimeline
AdvisorNet Financial, Inc1,696$7.21K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,456$6.19K<0.01%-15,55113F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,260$5.36K<0.01%+15113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA936$4K<0.01%+56513F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…547$2.33K<0.01%-9913F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP388$1.65K<0.01%new13F-HRTimelineGroup
SBI Securities Co., Ltd.6$26<0.01%013F-HRTimeline