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Disclosery

KPTI KARYOPHARM THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 1503802

48 managers (48 13F filers) reported a position in KPTI shares at 2025-03-31, 3,272,132 shares in all. 48 filers opened a position and 0 filers sold out during the quarter.

Managers
48
13F filers
48
New
48
Added
0
Reduced
0
Sold out
0
Shares held by filers
3,272,132

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
VANGUARD GROUP INCin group VANGUARD GROUP INC510,294$1.91M<0.01%new13F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…421,322$1.58M<0.01%new13F-HRTimelineGroup
Eversept Partners, LP257,154$962K0.11%new13F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.242,742$908K<0.01%new13F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC206,909$774K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO170,790$639K<0.01%new13F-HRTimelineGroup
Catalio Capital Management, LP155,622$582K0.14%new13F-HRTimeline
T. Rowe Price Investment Management, In…139,646$523K<0.01%new13F-HRTimeline
Avidity Partners Management LP134,566$503K0.1%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/132,908$497K<0.01%new13F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP128,451$480K<0.01%new13F-HRTimelineGroup
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S100,000$374K<0.01%new13F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC99,640$373K<0.01%new13F-HRTimelineGroup
UBS Group AGin group UBS Group AG93,612$350K<0.01%new13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC85,410$319K<0.01%new13F-HR/ATimelineGroup
RENAISSANCE TECHNOLOGIES LLC61,214$229K<0.01%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC55,367$207K<0.01%new13F-HRTimelineGroup
Altium Capital Management LLC49,333$185K0.54%new13F-HR/ATimeline
STATE STREET CORPin group STATE STREET CORP29,495$110K<0.01%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS28,961$108K<0.01%new13F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC27,257$102K0.03%new13F-HRTimelineGroup
Shay Capital LLC25,417$95.1K0.03%new13F-HRTimeline
OCONNOR, A Distinct Business Unit of UB…23,640$88.4K<0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
NORTHERN TRUST CORPin group NORTHERN TRUST CORP18,910$70.7K<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…11,548$43.2K<0.01%new13F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC11,420$42.7K<0.01%new13F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp11,086$41.5K<0.01%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY10,423$39K<0.01%new13F-HRTimelineGroup
Leonteq Securities AG10,000$37.3K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC7,044$26.3K<0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC5,333$19.9K<0.01%new13F-HR/ATimelineGroup
TD Waterhouse Canada Inc.3,203$11.3K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,459$5K<0.01%new13F-HR/ATimelineGroup
FMR LLCin group FMR LLC527$1.97K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.346$1.29K<0.01%new13F-HRTimelineGroup
COLDSTREAM CAPITAL MANAGEMENT INC331$1.24K<0.01%new13F-HRTimeline
Quent Capital, LLC231$864<0.01%new13F-HRTimeline
VSM Wealth Advisory, LLC133$497<0.01%new13F-HRTimeline
MB, LEVIS & ASSOCIATES, LLC100$374<0.01%new13F-HRTimeline
HARBOUR INVESTMENTS, INC.85$318<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.74$277<0.01%new13F-HRTimeline
Activest Wealth Management66$247<0.01%new13F-HRTimeline
Allworth Financial LP32$192<0.01%new13F-HRTimeline
Bruce G. Allen Investments, LLC22$82<0.01%new13F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.3$12<0.01%new13F-HRTimelineGroup
West Branch Capital LLC3$12<0.01%new13F-HRTimeline
DANSKE BANK A/S3$11<0.01%new13F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0new13F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • ACORN BIOVENTURES, L.P. and 4 other reporting persons reported 1,021,668 KPTI shares, 4.5% of the class, as of 2026-10-02, in a 13G/A filed 2026-10-08. 0001636587-26-000086

    Accepted , ingested

  • ACORN BIOVENTURES, L.P. and 4 other reporting persons reported 1,284,221 KPTI shares, 5.7% of the class, as of 2026-09-22, in a 13G/A filed 2026-09-25. 0001636587-26-000084

    Accepted , ingested

  • ACORN BIOVENTURES, L.P. and 4 other reporting persons reported 1,284,221 KPTI shares, 5.7% of the class, as of 2026-09-22, in a 13G/A filed 2026-09-25. 0001636587-26-000083

    Accepted , ingested