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Disclosery

IONS IONIS PHARMACEUTICALS INC

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Stock (common), issuer CIK 874015

429 managers (437 13F filers) reported a position in IONS shares at 2025-09-30, 168,163,384 shares in all. 111 filers opened a position and 37 filers sold out during the quarter.

Managers
429
13F filers
437
New
111
Added
136
Reduced
116
Sold out
37
Shares held by filers
168,163,384

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Point72 (DIFC) Ltd15,698$1.03M0.07%+7,61113F-HRTimeline
DIVERSIFIED TRUST CO15,633$1.02M0.02%new13F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…15,589$1.02M<0.01%013F-HRTimeline
IQ EQ FUND MANAGEMENT (IRELAND) Ltd15,284$1000K0.07%+2,02113F-HRTimeline
Significant Wealth Partners LLC14,967$979K0.48%-53713F-HRTimeline
Dynasty Wealth Management, LLC14,341$938K0.01%new13F-HRTimeline
BROWN ADVISORY INCin group BROWN ADVISORY INC14,026$918K<0.01%+1,83513F-HRTimelineGroup
Bleakley Financial Group, LLC13,878$908K0.02%-4,25113F-HRTimeline
Aigen Investment Management, LP13,578$888K0.14%+5,28013F-HRTimeline
Fieldview Capital Management, LLC13,523$885K0.14%-3,78313F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC13,349$873K<0.01%-59313F-HRTimeline
Westmount Partners, LLC12,961$853K0.22%013F-HRTimeline
Annis Gardner Whiting Capital Advisors,…12,801$837K0.17%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…12,782$836K<0.01%+53813F-HRTimelineGroup
&PARTNERS12,663$828K0.01%+90513F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…12,476$816K0.23%013F-HRTimelineGroup
HORIZON KINETICS ASSET MANAGEMENT LLC12,476$816K0.01%+52413F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding12,593$816K-626Timeline
NEOS Investment Management LLC12,306$805K0.01%-15,85513F-HRTimeline
Tema ETFs LLC12,306$805K0.07%-15,85513F-HRTimeline
AMALGAMATED BANK12,195$798K0.01%+66913F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…12,113$792K<0.01%+70213F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC11,551$756K0.01%-44913F-HRTimelineGroup
Allianz SEgroup of 2 filers holding11,500$752K+9,400Timeline
Blueshift Asset Management, LLC11,460$750K0.23%new13F-HRTimeline
Plancorp, LLC11,208$733K0.02%013F-HRTimeline
MONTANOVA CAPITAL, LLC10,800$707K0.02%013F-HRTimeline
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…10,402$680K0.01%new13F-HRTimelineGroup
Baader Bank Aktiengesellschaft10,228$668K0.06%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.10,169$665K0.01%-12,21213F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP10,172$665K0.06%new13F-HRTimeline
Cypress Capital, LLC10,000$654K0.19%013F-HRTimeline
denkapparat Operations GmbH9,968$652K0.42%new13F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…9,962$652K<0.01%new13F-HRTimelineGroup
Orion Porfolio Solutions, LLC9,962$652K0.01%+4,36213F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.10,167$618K<0.01%+4,87113F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…9,428$617K<0.01%+26713F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC9,344$611K<0.01%+9013F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS9,308$609K<0.01%-2,96313F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC9,205$602K0.37%013F-HRTimeline
Utah Retirement Systems8,300$543K0.01%-10013F-HRTimeline
Maryland State Retirement & Pension Sys…8,284$542K0.01%013F-HRTimeline
Empire Financial Management Company, LLC8,000$523K0.12%new13F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…7,944$520K<0.01%+34613F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…7,439$513K<0.01%-47613F-HRTimeline
Stratos Wealth Partners, LTD.in group Stratos Wealth Partners, LTD.7,764$508K0.01%new13F-HRTimelineGroup
INCEPTIONR LLC7,621$499K0.12%new13F-HRTimeline
COMMERCE BANKin group COMMERCE BANK7,607$498K<0.01%013F-HRTimelineGroup
Meeder Advisory Services, Inc.group of 2 filers holding7,483$490K+740Timeline
Savant Capital, LLCin group Savant Capital, LLC7,237$473K<0.01%+1,66713F-HR/ATimelineGroup
SILVERCREST ASSET MANAGEMENT GROUP LLC7,118$466K<0.01%+5013F-HRTimeline
Atria Investments, Inc7,030$460K0.01%-1,15613F-HRTimeline
Cetera Investment Advisers6,873$450K<0.01%new13F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…6,827$447K<0.01%new13F-HRTimelineGroup
PRAXIS INVESTMENT MANAGEMENT INC6,770$443K0.03%013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd6,722$440K0.01%-76,63913F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC6,815$439K<0.01%new13F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP6,834$438K<0.01%-36213F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources6,593$431K<0.01%+1,03713F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP6,590$431K<0.01%-231,25013F-HRTimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co6,377$417K<0.01%-2,17413F-HRTimelineGroup
Fisher Asset Management, LLC6,210$406K<0.01%new13F-HRTimeline
Summit Trail Advisors, LLC6,205$406K0.01%new13F-HRTimeline
PEAK6 LLCin group PEAK6 LLC6,112$400K0.01%new13F-HR/ATimelineGroup
M&T Bank Corpin group M&T Bank Corp6,010$393K<0.01%-1,64113F-HRTimelineGroup
Frank, Rimerman Advisors LLC5,765$377K0.02%+213F-HRTimeline
ProShare Advisors LLC5,678$371K<0.01%-26513F-HRTimeline
Wedmont Private Capital5,363$370K0.01%+8113F-HRTimeline
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…5,463$357K0.52%new13F-HRTimelineGroup
HighTower Advisors, LLC5,458$357K<0.01%+10113F-HRTimeline
Advisors Asset Management, Inc.5,454$357K0.01%-54513F-HR/ATimeline
Edgestream Partners, L.P.5,450$357K0.01%new13F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…5,407$354K<0.01%+913F-HRTimelineGroup
O'SHAUGHNESSY ASSET MANAGEMENT, LLC5,297$347K<0.01%new13F-HRTimeline
SG Americas Securities, LLC5,150$337K<0.01%new13F-HRTimeline
Pinnacle Wealth Planning Services, Inc.5,113$334K0.04%-17113F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…8,207$328K0.03%013F-HRTimeline
Moisand Fitzgerald Tamayo, LLC5,000$327K0.04%013F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC4,972$325K<0.01%new13F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding4,896$320K-3,118Timeline
NewEdge Advisors, LLC4,822$315K<0.01%+4,62613F-HRTimeline
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP4,812$315K<0.01%new13F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.4,800$314K<0.01%new13F-HR/ATimeline
GROUP ONE TRADING LLC4,796$314K0.01%new13F-HRTimeline
Requisite Capital Management, LLC4,734$310K0.05%new13F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A4,710$308K<0.01%13F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\4,704$308K<0.01%+41913F-HRTimelineGroup
KBC Group NVin group KBC Group NV4,699$307K<0.01%013F-HRTimelineGroup
CIBC Asset Management Inc4,608$301K<0.01%new13F-HRTimeline
Prospera Financial Services Inc4,581$300K0.01%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…4,516$295K<0.01%-28,21613F-HRTimelineGroup
COLDSTREAM CAPITAL MANAGEMENT INC4,479$293K<0.01%new13F-HRTimeline
Perbak Capital Partners LLP4,426$290K0.05%-5,11213F-HRTimeline
Checchi Capital Advisers, LLC4,233$277K0.02%new13F-HRTimeline
PITCAIRN COin group PITCAIRN CO4,075$267K0.02%new13F-HRTimelineGroup
Prime Capital Investment Advisors, LLC3,934$257K<0.01%new13F-HRTimeline
REGIONS FINANCIAL CORPin group REGIONS FINANCIAL CORP3,800$249K<0.01%new13F-HR/ATimelineGroup
MERCER GLOBAL ADVISORS INC /ADV3,747$245K<0.01%new13F-HRTimeline
STRS OHIO3,716$243K<0.01%+213F-HRTimeline
NWAM LLC3,238$238K0.01%new13F-HR/ATimeline
Sanctuary Advisors, LLC3,637$238K<0.01%new13F-HR/ATimeline
BERKSHIRE ASSET MANAGEMENT LLC/PA3,614$236K0.01%new13F-HRTimeline
MACKENZIE FINANCIAL CORP3,588$235K<0.01%new13F-HRTimeline
OneDigital Investment Advisors LLC3,588$235K<0.01%new13F-HRTimeline
PharVision Advisers, LLC3,587$235K0.13%new13F-HRTimeline
MITCHELL & PAHL PRIVATE WEALTH, LLC3,572$234K0.1%new13F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA3,509$230K<0.01%new13F-HRTimelineGroup
Massar Capital Management, LP3,462$226K0.08%new13F-HRTimeline
EntryPoint Capital, LLC3,458$226K0.09%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,429$224K<0.01%-61313F-HRTimeline
Victrix Investment Advisors3,400$222K0.12%new13F-HRTimeline
ANB BANK3,231$211K0.09%new13F-HRTimeline
Raab & Moskowitz Asset Management LLC3,115$204K0.05%new13F-HRTimeline
WESTFIELD CAPITAL MANAGEMENT CO LP3,093$202K<0.01%-6,46813F-HRTimeline
Voleon Capital Management LP3,060$200K<0.01%new13F-HRTimeline
Point72 Europe (London) LLP3,051$200K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,045$199K0.01%+1,46413F-HRTimelineGroup
CWM, LLCin group CWM, LLC2,488$163K<0.01%+17013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…2,203$144K<0.01%new13F-HRTimelineGroup
COMERICA BANK2,187$143K<0.01%+57013F-HRTimeline
Ancora Advisors LLCin group Ancora Advisors LLC2,137$140K<0.01%+13713F-HRTimelineGroup
SIGNATUREFD, LLC2,003$131K<0.01%-2713F-HRTimeline
Parallel Advisors, LLC1,877$123K<0.01%+513F-HRTimeline
Harvest Fund Management Co., Ltdin group Harvest Fund Management Co., …1,746$114K<0.01%-8313F-HRTimelineGroup
Abich Financial Wealth Management LLC1,708$112K0.04%13F-HRTimeline
Twin Lakes Capital Management, LLC1,500$98.1K0.05%013F-HRTimeline
Versant Capital Management, Inc1,465$95.8K0.01%013F-HRTimeline
CI INVESTMENTS INC.in group CI INVESTMENTS INC.1,453$95K<0.01%-96313F-HRTimelineGroup
DANSKE BANK A/S1,400$91.6K<0.01%013F-HR/ATimeline
GAMMA Investing LLC1,341$87.7K<0.01%+41113F-HRTimeline
Root Financial Partners, LLC1,340$87.7K0.01%new13F-HRTimeline
Manchester Capital Management LLC1,248$81.6K0.01%013F-HRTimeline
WEXFORD CAPITAL LP1,192$78K0.02%-3,55713F-HRTimeline
Itau Unibanco Holding S.A.in group Itau Unibanco Holding S.A.1,121$73.3K<0.01%-313F-HRTimelineGroup
Larson Financial Group LLC1,110$72.6K<0.01%+8313F-HRTimeline
IFP Advisors, Inc1,070$70K<0.01%+16613F-HR/ATimeline
Steward Partners Investment Advisory, L…1,069$69.9K<0.01%-15213F-HRTimeline
Sunbelt Securities, Inc.1,014$66.3K<0.01%013F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK951$62.2K<0.01%new13F-HRTimelineGroup
Sterling Capital Management LLC898$58.7K<0.01%-6413F-HRTimeline
Allworth Financial LP840$55K<0.01%+10013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…827$54.1K<0.01%-27413F-HRTimelineGroup
Johnson Financial Group, Inc.in group Johnson Financial Group, Inc.670$43.8K<0.01%new13F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK654$42.8K<0.01%-14113F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC616$40.3K<0.01%new13F-HRTimeline
Archer Investment Corp600$39.3K0.01%013F-HRTimeline
Quarry LP588$38.5K0.01%new13F-HRTimeline
Farther Finance Advisors, LLC566$37K<0.01%+13313F-HRTimeline
AdvisorNet Financial, Inc469$30.7K<0.01%+4113F-HRTimeline
AlphaQuest LLC453$29.6K<0.01%-38213F-HRTimeline
MATHER GROUP, LLC.410$26.8K<0.01%new13F-HRTimeline
Ascentis Wealth Management, LLCin group Ascentis Wealth Management, L…400$26.2K0.01%013F-HRTimelineGroup
Steigerwald, Gordon & Koch Inc.380$24.9K<0.01%new13F-HRTimeline
Golden State Wealth Management, LLC376$24.6K<0.01%+25013F-HRTimeline
Salomon & Ludwin, LLC332$23K<0.01%new13F-HRTimeline
Global X Japan Co., Ltd.321$21K<0.01%+6213F-HRTimeline
EASTERN BANK300$19.6K<0.01%013F-HRTimeline
Capital Advisors, Ltd. LLC295$19K<0.01%013F-HRTimeline
Strategic Advocates LLC287$18.8K<0.01%new13F-HRTimeline
LANARK FINANCIAL, INC.273$17.9K<0.01%new13F-HRTimeline
STOREBRAND ASSET MANAGEMENT AS271$17.7K<0.01%013F-HRTimeline
MAI Capital Management267$17.5K<0.01%-15913F-HRTimeline
SBI Securities Co., Ltd.267$17.5K<0.01%+1013F-HRTimeline
Union Bancaire Privee, UBP SA265$17K<0.01%013F-HRTimeline
MTM Investment Management, LLC258$16.9K0.01%013F-HRTimeline
Wealthspire Advisors, LLC245$16K<0.01%new13F-HRTimeline
Covestor Ltd246$16K0.01%-5913F-HRTimeline
Parkside Financial Bank & Trust240$15.7K<0.01%-19813F-HRTimeline
Advisory Services Network, LLC238$15.5K<0.01%new13F-HRTimeline
Westside Investment Management, Inc.231$15.2K<0.01%013F-HRTimeline
Global Trust Asset Management, LLC218$14.3K0.01%013F-HRTimeline
HARBOUR INVESTMENTS, INC.210$13.7K<0.01%+1013F-HRTimeline
Atlantic Union Bankshares Corpin group Atlantic Union Bankshares Corp200$13.1K<0.01%013F-HRTimelineGroup
UMB Bank, n.a.200$13.1K<0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
AllSquare Wealth Management LLC198$13K0.01%013F-HRTimeline
Bayforest Capital Ltd154$10.1K<0.01%new13F-HRTimeline
Pacifica Partners Inc.150$9.87K<0.01%013F-HRTimeline
Wealth Preservation Advisors, LLC150$9.81K0.01%013F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC133$9K<0.01%+9413F-HRTimelineGroup
Spire Wealth Managementin group Spire Wealth Management125$8.18K<0.01%013F-HRTimelineGroup
GPS Wealth Strategies Group, LLC119$7.79K<0.01%013F-HRTimeline
Bogart Wealth, LLC118$7.72K<0.01%013F-HRTimeline
Smartleaf Asset Management LLC104$6.67K<0.01%new13F-HRTimeline
Creekmur Asset Management LLC100$6.54K<0.01%013F-HRTimeline
Quent Capital, LLC98$6.41K<0.01%new13F-HRTimeline
MassMutual Private Wealth & Trust, FSB89$5.82K<0.01%-1413F-HRTimeline
Ameritas Advisory Services, LLCin group Ameritas Investment Partners,…87$5.69K<0.01%-5913F-HRTimelineGroup
TD PRIVATE CLIENT WEALTH LLC80$5.23K<0.01%+3613F-HRTimeline
Orion Capital Management LLC80$5.23K<0.01%013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC75$4.91K<0.01%013F-HRTimelineGroup
CLEAR INVESTMENT RESEARCH, LLC71$4.64K0.01%013F-HRTimeline
WPG Advisers, LLC70$4.58K<0.01%013F-HRTimeline
Private Wealth Management Group, LLC65$4.25K<0.01%013F-HRTimeline
Leonteq Securities AG63$4.12K<0.01%013F-HRTimeline
Bell Investment Advisors, Inc61$3.99K<0.01%013F-HRTimeline
Crewe Advisors LLC48$3.14K<0.01%new13F-HRTimeline
FIL Ltdin group FIL Ltd47$3.08K<0.01%new13F-HRTimelineGroup
CoreCap Advisors, LLC45$2.94K<0.01%013F-HRTimeline
Sachetta, LLC45$2.94K<0.01%013F-HRTimeline
HIGHLINE WEALTH PARTNERS LLC38$2.49K<0.01%013F-HRTimeline