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Disclosery

IONS IONIS PHARMACEUTICALS INC

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Stock (common), issuer CIK 874015

500 managers (513 13F filers) reported a position in IONS shares at 2026-06-30, 179,711,084 shares in all. 62 filers opened a position and 46 filers sold out during the quarter.

Managers
500
13F filers
513
New
62
Added
201
Reduced
160
Sold out
46
Shares held by filers
179,711,084

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
XPONANCE LLC26,687$2.12M0.01%+30313F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC26,041$2.06M0.02%-12,47413F-HRTimeline
JUPITER ASSET MANAGEMENT LTDin group JUPITER ASSET MANAGEMENT LTD25,949$2.06M0.01%new13F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/25,782$2.04M<0.01%-80313F-HRTimelineGroup
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…25,727$2.04M0.02%new13F-HRTimelineGroup
Orion Porfolio Solutions, LLC24,870$1.97M0.02%-36,47413F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co24,515$1.94M<0.01%+2,38013F-HRTimelineGroup
INCEPTIONR LLC24,251$1.92M0.47%+7,43013F-HRTimeline
Dana Investment Advisors, Inc.23,272$1.85M0.05%+4,78513F-HRTimeline
WOLVERINE ASSET MANAGEMENT LLCin group WOLVERINE ASSET MANAGEMENT LLC22,340$1.77M0.02%-47513F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC22,059$1.75M<0.01%-6,72413F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…21,945$1.74M0.01%-2,13813F-HRTimeline
Cetera Investment Advisers21,808$1.73M<0.01%+10,52813F-HRTimeline
Nicollet Investment Management, Inc.20,240$1.6M0.5%+59413F-HRTimeline
Amundiin group Amundi20,190$1.6M<0.01%-3,76813F-HRTimelineGroup
PROFUND ADVISORS LLC18,321$1.45M0.04%-7,96613F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS17,986$1.43M<0.01%-1,07413F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP17,306$1.37M0.09%+14,13413F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP16,943$1.34M0.01%-3,62213F-HRTimelineGroup
Graham Capital Management, L.P.16,717$1.33M0.04%new13F-HRTimeline
NORTH STAR ASSET MANAGEMENT INC16,560$1.31M0.05%-5013F-HRTimeline
BIT Capital GmbH16,300$1.29M0.04%new13F-HRTimeline
Mitsubishi UFJ Trust & Banking Corpgroup of 2 filers holding16,064$1.27M+13,371Timeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…15,870$1.26M0.29%+5,42513F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC15,846$1.26M<0.01%+74113F-HRTimelineGroup
IQ EQ FUND MANAGEMENT (IRELAND) Ltd15,819$1.25M0.08%+1,43013F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP15,511$1.23M0.08%new13F-HRTimeline
AlphaCentric Advisors LLC15,430$1.22M1.04%-4,15713F-HRTimeline
Engineers Gate Manager LP14,840$1.18M0.02%-118,98713F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.14,800$1.17M<0.01%+6,09013F-HRTimelineGroup
Bleakley Financial Group, LLC14,793$1.17M0.01%+47713F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…14,185$1.12M<0.01%+64013F-HRTimelineGroup
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP14,068$1.12M<0.01%+1,22213F-HRTimelineGroup
BAMCO INC /NY/in group Baron Capital14,000$1.11M<0.01%-31,00013F-HRTimelineGroup
Summit Trail Advisors, LLC13,931$1.1M0.01%+2,38213F-HRTimeline
FORA Capital, LLC13,833$1.1M0.08%-5,86013F-HRTimeline
OPPENHEIMER ASSET MANAGEMENT INC.in group OPPENHEIMER ASSET MANAGEMENT …13,752$1.09M0.01%+1,89913F-HRTimelineGroup
Dynasty Wealth Management, LLC13,661$1.08M0.01%-41913F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al13,400$1.06M0.01%+3,10013F-HRTimeline
Westmount Partners, LLC12,961$1.03M0.23%013F-HRTimeline
SBI Okasan Asset Management Co.Ltd.12,600$1.02M0.03%013F-HRTimeline
Annis Gardner Whiting Capital Advisors,…12,801$1.01M0.15%013F-HRTimeline
Man Group plcin group Man Group plc12,361$980K<0.01%-11,65213F-HRTimelineGroup
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…12,338$978K0.29%-26,65013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding12,240$977K-1,062Timeline
Allianz Asset Management GmbHin group Allianz SE12,829$971K<0.01%+22813F-HRTimelineGroup
Federation des caisses Desjardins du Qu…12,017$953K<0.01%+2,01213F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC11,808$936K0.02%-64,76313F-HRTimeline
COMMERCE BANKin group COMMERCE BANK11,681$926K<0.01%+3,51613F-HRTimelineGroup
AMALGAMATED BANK11,519$913K0.01%-53513F-HRTimeline
Militia Capital Management LLCin group Militia Capital Management LLC11,400$904K0.16%new13F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…10,925$866K<0.01%-19813F-HRTimelineGroup
HORIZON KINETICS ASSET MANAGEMENT LLC10,904$865K0.01%-52413F-HRTimeline
MONTANOVA CAPITAL, LLC10,800$856K0.02%013F-HRTimeline
EVOLVE PRIVATE WEALTH, LLC10,653$845K0.05%new13F-HRTimeline
AXQ CAPITAL, LP10,423$826K0.09%+6,57713F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…10,275$815K<0.01%+1,10013F-HRTimelineGroup
Marex Group Ltdin group Marex Group Ltd10,189$808K0.01%+6,57913F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC10,187$808K0.01%+69813F-HRTimelineGroup
&PARTNERS10,184$807K<0.01%-72513F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…10,061$798K<0.01%-95013F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC9,939$788K<0.01%+36513F-HRTimelineGroup
MACKENZIE FINANCIAL CORP9,289$737K<0.01%+5,49413F-HRTimeline
Ensign Peak Advisors, Inc9,120$723K<0.01%-36,88413F-HRTimeline
NewEdge Wealth, LLC8,977$712K0.01%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…8,776$696K<0.01%-44813F-HRTimelineGroup
iA Global Asset Management Inc.8,658$686K0.01%new13F-HRTimeline
Utah Retirement Systems8,577$680K0.01%+27713F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP8,501$674K<0.01%-87,45313F-HRTimelineGroup
denkapparat Operations GmbH8,364$663K0.22%013F-HRTimeline
Maryland State Retirement & Pension Sys…8,343$662K0.01%+96313F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC8,153$646K<0.01%+32413F-HRTimeline
Inspire Investing, LLCgroup of 2 filers holding8,127$644K+4,007Timeline
Plancorp, LLC11,128$632K0.02%-8013F-HRTimeline
Stratos Wealth Partners, LTD.in group Stratos Wealth Partners, LTD.7,801$619K0.01%+8613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding7,774$616K-100,545Timeline
Meeder Advisory Services, Inc.group of 2 filers holding7,732$613K+341Timeline
M&T Bank Corpin group M&T Bank Corp7,510$595K<0.01%+31213F-HRTimelineGroup
Savant Capital, LLC7,476$588K<0.01%-98513F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co7,399$587K0.01%013F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC7,200$571K0.4%013F-HRTimeline
O'SHAUGHNESSY ASSET MANAGEMENT, LLC7,166$568K<0.01%-52113F-HRTimeline
Callan Family Office, LLCin group Callan Family Office, LLC7,143$566K0.01%+6113F-HRTimelineGroup
SILVERCREST ASSET MANAGEMENT GROUP LLC7,055$559K<0.01%+213F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV6,918$548K<0.01%+62213F-HR/ATimeline
PSP Research LLC6,800$539K0.29%013F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG6,751$535K0.01%+32013F-HRTimelineGroup
Significant Wealth Partners LLC6,613$524K0.57%-5113F-HRTimeline
GROUP ONE TRADING LLC6,493$515K0.01%+4,60113F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\6,366$505K<0.01%+1,31913F-HRTimelineGroup
PRAXIS INVESTMENT MANAGEMENT INC6,232$494K0.03%013F-HRTimeline
Nykredit A/Sin group Nykredit A/S6,154$488K<0.01%13F-HRTimelineGroup
Janney Montgomery Scott LLC6,138$487K<0.01%new13F-HRTimeline
MCF Advisors LLC6,136$487K0.02%+6,08613F-HRTimeline
Cypress Capital, LLC6,000$476K0.13%013F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC5,989$475K<0.01%-1,60713F-HRTimelineGroup
Frank, Rimerman Advisors LLC5,807$460K0.03%+2613F-HRTimeline
REGIONS FINANCIAL CORPin group REGIONS FINANCIAL CORP5,604$444K<0.01%-51813F-HRTimelineGroup
Robeco Institutional Asset Management B…in group Robeco Institutional Asset Ma…5,578$442K<0.01%-8213F-HRTimelineGroup
E Fund Management Co., Ltd.5,569$442K0.01%-41,11913F-HRTimeline
Tema ETFs LLC5,525$438K0.01%-14813F-HRTimeline
ProShare Advisors LLC5,417$430K<0.01%-1,97313F-HRTimeline
VARCOV Co.5,390$427K0.16%new13F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC5,352$424K0.01%-30113F-HRTimeline
OneDigital Investment Advisors LLC5,345$424K<0.01%-4513F-HRTimeline
R Squared Ltd5,313$421K0.22%+95413F-HRTimeline
CAPTRUST FINANCIAL ADVISORS5,030$399K<0.01%+3013F-HRTimeline
Granite Investment Partners, LLC5,026$399K0.02%-31913F-HRTimeline
CIBC Asset Management Inc5,017$398K<0.01%013F-HRTimeline
Moisand Fitzgerald Tamayo, LLC5,000$396K0.04%013F-HRTimeline
AlphaCore Capital LLC4,986$395K0.01%+2,22413F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.4,957$393K<0.01%-28313F-HRTimelineGroup
Wedmont Private Capital6,723$392K0.01%+15913F-HRTimeline
NewEdge Advisors, LLC4,822$382K<0.01%+3613F-HRTimeline
Quantbot Technologies LP4,812$382K0.02%new13F-HRTimeline
AZZAD ASSET MANAGEMENT INC /ADV4,784$379K0.03%new13F-HRTimeline
North Dakota State Investment Board4,703$373K0.02%+8013F-HRTimeline
Atria Investments, Inc4,690$372K<0.01%-53713F-HRTimeline
GATEWAY INVESTMENT ADVISERS LLC4,630$367K<0.01%new13F-HRTimeline
Blueshift Asset Management, LLC4,433$351K0.08%+1,65613F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A4,410$350K<0.01%013F-HRTimelineGroup
Yorktown Management & Research Co Inc4,400$349K0.21%new13F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC4,384$348K<0.01%+1213F-HRTimelineGroup
INTRUST BANK NA4,339$344K0.03%+28313F-HRTimeline
Checchi Capital Advisers, LLC4,308$342K0.02%-12113F-HRTimeline
WESTFIELD CAPITAL MANAGEMENT CO LP4,233$336K<0.01%+73113F-HRTimeline
Prospera Financial Services Inc4,194$333K<0.01%-14713F-HRTimeline
HighTower Advisors, LLC4,084$324K<0.01%+28713F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…5,394$314K<0.01%+1,26913F-HRTimeline
Prime Capital Investment Advisors, LLC3,938$312K<0.01%-3313F-HRTimeline
Sanctuary Advisors, LLC3,938$312K<0.01%+2013F-HRTimeline
Qsemble Capital Management, LP3,887$308K0.04%-21,87113F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,832$304K<0.01%-32313F-HRTimelineGroup
Pinnacle Wealth Planning Services, Inc.3,780$300K0.03%-43313F-HRTimeline
Bridgefront Capital, LLC3,778$300K0.08%new13F-HRTimeline
ANB BANK3,733$296K0.11%-3613F-HRTimeline
Eurizon Capital SGR S.p.A.3,639$294K<0.01%+12513F-HRTimeline
PARK AVENUE SECURITIES LLCin group PARK AVENUE SECURITIES LLC3,677$292K<0.01%new13F-HRTimelineGroup
BERKSHIRE ASSET MANAGEMENT LLC/PA3,630$288K0.01%-713F-HRTimeline
Crossmark Global Holdings, Inc.3,615$287K<0.01%+41613F-HRTimeline
MML INVESTORS SERVICES, LLC3,600$285K<0.01%+42713F-HRTimeline
Sequoia Financial Advisors, LLC3,567$283K<0.01%new13F-HRTimeline
Everhart Financial Group, Inc.3,503$278K0.02%+3313F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,497$277K<0.01%-14013F-HRTimeline
Perigon Wealth Management, LLC3,477$276K<0.01%+4713F-HRTimeline
New York Life Investment Management LLCin group New York Life Investment Mana…3,458$274K<0.01%+77013F-HRTimelineGroup
Victrix Investment Advisors3,400$270K0.11%new13F-HRTimeline
MITCHELL & PAHL PRIVATE WEALTH, LLC3,261$259K0.09%013F-HRTimeline
NWAM LLC3,238$257K0.01%013F-HRTimeline
Raab & Moskowitz Asset Management LLC3,115$247K0.05%013F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.3,079$244K<0.01%-1513F-HRTimeline
M&G PLCin group M&G PLC3,090$244K<0.01%-11,33313F-HRTimelineGroup
Venturi Wealth Management, LLC3,061$243K0.01%013F-HRTimeline
HB Wealth Management, LLC3,025$240K<0.01%+9913F-HRTimeline
Argent Trust Co3,018$239K0.01%013F-HRTimeline
Larson Financial Group LLC3,000$238K0.01%-3113F-HRTimeline
B. Riley Wealth Advisors, Inc.2,897$234K0.01%-4813F-HRTimeline
AlphaGrep UK Ltd2,946$234K0.07%new13F-HRTimeline
Integrated Wealth Concepts LLC2,926$232K<0.01%+20213F-HRTimeline
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT…2,923$232K0.03%new13F-HRTimeline
Cambria Investment Management, L.P.2,885$229K0.01%013F-HRTimeline
Voleon Capital Management LP2,862$227K<0.01%-20,18513F-HRTimeline
Montis Financial, LLC2,700$214K0.04%013F-HRTimeline
NORDEN GROUP LLC2,685$213K0.02%-20413F-HRTimeline
IFG Advisory, LLC2,678$212K0.01%new13F-HRTimeline
KOM Wealth Management Group, LLC2,654$210K0.13%new13F-HRTimeline
Mesirow Financial Investment Management…2,530$201K<0.01%-2,93013F-HRTimeline
Steward Partners Investment Advisory, L…2,355$187K<0.01%-1,28413F-HRTimeline
Global Retirement Partners, LLC2,282$181K<0.01%13F-HRTimeline
Ancora Advisors LLCin group Ancora Advisors LLC2,215$176K<0.01%-17613F-HRTimelineGroup
GAMMA Investing LLC2,168$172K0.01%+40213F-HRTimeline
State of Wyoming2,024$160K0.02%new13F-HRTimeline
SIGNATUREFD, LLC1,880$149K<0.01%-19813F-HRTimeline
Caption Management, LLC1,759$139K<0.01%-13,83213F-HRTimeline
Parallel Advisors, LLC1,684$134K<0.01%-19913F-HRTimeline
Versant Capital Management, Inc1,460$116K0.01%-9513F-HRTimeline
Smartleaf Asset Management LLC1,416$114K<0.01%013F-HRTimeline
HARBOR INVESTMENT ADVISORY, LLC1,407$112K0.01%new13F-HRTimeline
Sterling Capital Management LLC1,289$102K<0.01%-13613F-HRTimeline
Graticule Asia Macro Advisors LLC1,264$100K0.01%new13F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…1,232$97.6K0.01%+1113F-HRTimeline
Farther Finance Advisors, LLC1,111$88.2K<0.01%-77213F-HRTimeline
IMA Advisory Services, Inc.1,037$82.2K0.01%+1,00913F-HRTimeline
Arax Advisory Partners1,004$79.6K<0.01%new13F-HRTimeline
IFP Advisors, Inc952$75.5K<0.01%+213F-HRTimeline
AdvisorNet Financial, Inc904$71.7K<0.01%+33113F-HRTimeline
Tripletail Wealth Management, LLC850$69.5K0.08%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…858$68K<0.01%-93613F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK734$58.2K<0.01%+5313F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC700$55.5K<0.01%013F-HRTimeline
Pacer Advisors, Inc.629$50K<0.01%new13F-HRTimeline
Archer Investment Corp600$47.6K0.01%013F-HR/ATimeline
NISA INVESTMENT ADVISORS, LLC580$46K<0.01%+57913F-HRTimeline
HARBOUR INVESTMENTS, INC.558$44.3K<0.01%+1213F-HRTimeline
Silvant Capital Management LLC540$42.8K<0.01%new13F-HRTimeline
Allworth Financial LP516$40.9K<0.01%-613F-HRTimeline
MATHER GROUP, LLC.410$32.5K<0.01%013F-HRTimeline
Cassaday & Co Wealth Management LLC400$31.7K<0.01%013F-HRTimeline
Ascentis Wealth Management, LLCin group Ascentis Wealth Management, L…400$31.7K<0.01%013F-HR/ATimelineGroup
Golden State Wealth Management, LLC376$29.8K<0.01%013F-HRTimeline