BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 3,466,000 $45.4M 1.54% 0 13F-HR Timeline Group BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 2,678,553 $35.1M 0.37% +803,575 13F-HR Timeline Group Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 2,565,087 $33.6M 2.54% +1,319,700 13F-HR Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 2,362,279 $30.9M 0.86% 0 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 2,179,064 $28.5M <0.01% +368,616 13F-HR Timeline Group VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 1,651,981 $21.6M <0.01% +24,429 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 1,265,653 $16.6M 0.3% -269,347 13F-HR Timeline SAMLYN CAPITAL, LLC in group SAMLYN CAPITAL, LLC More: the full row for SAMLYN CAPITAL, LLC 1,251,593 $16.4M 0.26% -39,342 13F-HR Timeline Group NEA Management Company, LLC More: the full row for NEA Management Company, LLC 1,250,001 $16.4M 0.92% 0 13F-HR Timeline Saturn V Capital Management LP More: the full row for Saturn V Capital Management LP 1,063,783 $13.9M 5.45% +117,448 13F-HR Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 884,306 $11.6M 0.34% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 879,792 $11.5M <0.01% -227,623 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 876,891 $11.5M <0.01% -515,814 13F-HR/A Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 836,023 $10.9M 0.01% +61,095 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 692,372 $9.07M <0.01% +62,003 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 648,118 $8.47M <0.01% new 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 610,500 $7.99M 0.9% 0 13F-HR Timeline Artisan Partners Limited Partnership More: the full row for Artisan Partners Limited Partnership 491,507 $6.43M 0.01% +75,830 13F-HR Timeline CAPTRUST FINANCIAL ADVISORS More: the full row for CAPTRUST FINANCIAL ADVISORS 468,096 $6.13M 0.02% +6,302 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 447,171 $5.85M <0.01% +140,642 13F-HR Timeline Group Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 400,000 $5.24M 0.38% -1,122,332 13F-HR Timeline Group Cunning Capital Partners, LP More: the full row for Cunning Capital Partners, LP 52,465 $4.84M 2.9% 0 13F-HR Timeline Pfizer Inc More: the full row for Pfizer Inc 349,406 $4.57M 0.18% 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 300,076 $3.93M <0.01% +42,186 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 288,259 $3.77M <0.01% +10,907 13F-HR Timeline Group Candriam S.C.A. More: the full row for Candriam S.C.A. 263,590 $3.45M 0.02% new 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 237,706 $3.11M <0.01% +16,035 13F-HR Timeline Group PFM Health Sciences, LP More: the full row for PFM Health Sciences, LP 158,746 $2.08M 0.16% -551,509 13F-HR Timeline Hennion & Walsh Asset Management, Inc. More: the full row for Hennion & Walsh Asset Management, Inc. 144,032 $1.89M 0.09% +71,006 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 117,759 $1.54M <0.01% +17,056 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP group of 2 filers holding More: the full row for TWO SIGMA INVESTMENTS, LP 103,038 $1.35M -84,769 Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 83,914 $1.1M <0.01% +10,631 13F-HR Timeline Group Nuveen Asset Management, LLC in group TIAA More: the full row for Nuveen Asset Management, LLC 69,587 $911K <0.01% +6,785 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 64,125 $839K <0.01% +10,828 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 63,575 $832K <0.01% -32,701 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 62,776 $822K <0.01% +11,165 13F-HR Timeline Group Focus Partners Wealth in group Focus Partners Wealth More: the full row for Focus Partners Wealth 58,000 $759K <0.01% 0 13F-HR/A Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 57,199 $749K <0.01% +3,594 13F-HR/A Timeline Group GAGNON SECURITIES LLC in group GAGNON SECURITIES LLC More: the full row for GAGNON SECURITIES LLC 52,479 $687K 0.14% -314 13F-HR Timeline Group J. Goldman & Co LP More: the full row for J. Goldman & Co LP 43,345 $567K 0.02% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 39,660 $519K <0.01% -113,721 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 38,808 $508K <0.01% +19,373 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 38,755 $507K <0.01% +6,625 13F-HR/A Timeline JNBA Financial Advisors More: the full row for JNBA Financial Advisors 38,091 $499K 0.05% 0 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 30,878 $404K <0.01% -25,709 13F-HR Timeline ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 30,028 $393K <0.01% -65 13F-HR Timeline Group PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 29,740 $389K <0.01% -860 13F-HR Timeline Group Accredited Investors Inc. More: the full row for Accredited Investors Inc. 29,115 $381K 0.02% 0 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 28,391 $372K <0.01% +3,682 13F-HR/A Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 26,484 $347K <0.01% -301,469 13F-HR Timeline Group WEALTH ENHANCEMENT ADVISORY SERVICES, L… More: the full row for WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 26,377 $345K <0.01% +4,341 13F-HR/A Timeline Verition Fund Management LLC More: the full row for Verition Fund Management LLC 25,991 $340K <0.01% -13,925 13F-HR Timeline ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 25,000 $327K 0.33% -21,600 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 23,680 $310K <0.01% 0 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 22,842 $299K <0.01% +9,174 13F-HR/A Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 21,316 $279K <0.01% new 13F-HR Timeline Group EntryPoint Capital, LLC More: the full row for EntryPoint Capital, LLC 20,847 $273K 0.11% -28 13F-HR Timeline MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 20,384 $267K <0.01% +6,669 13F-HR Timeline Group Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 20,122 $263K 0.01% -9,750 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 19,725 $258K <0.01% +2,756 13F-HR Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 19,235 $252K 0.02% new 13F-HR Timeline Cresset Asset Management, LLC More: the full row for Cresset Asset Management, LLC 18,510 $242K <0.01% -18,984 13F-HR Timeline TRUST POINT INC. More: the full row for TRUST POINT INC. 17,847 $234K 0.02% -548 13F-HR Timeline Pale Fire Capital SE in group Pale Fire Capital More: the full row for Pale Fire Capital SE 17,458 $229K 0.05% 0 13F-HR Timeline Group INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 16,649 $218K <0.01% new 13F-HR Timeline Corebridge Financial, Inc. in group Corebridge Financial, Inc. More: the full row for Corebridge Financial, Inc. 16,256 $213K <0.01% +1,858 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 15,515 $203K <0.01% +6,976 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 14,683 $192K <0.01% +2,676 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 14,646 $192K <0.01% +6,651 13F-HR Timeline Shay Capital LLC More: the full row for Shay Capital LLC 14,300 $187K 0.05% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 12,721 $167K <0.01% new 13F-HR Timeline Corton Capital Inc. More: the full row for Corton Capital Inc. 11,773 $154K 0.09% -9 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 11,640 $152K <0.01% new 13F-HR Timeline Bleakley Financial Group, LLC More: the full row for Bleakley Financial Group, LLC 11,159 $146K <0.01% new 13F-HR Timeline Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 10,924 $143K <0.01% +558 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 10,826 $142K <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 9,219 $120K <0.01% -1,288 13F-HR Timeline Group AlphaQuest LLC More: the full row for AlphaQuest LLC 7,894 $103K 0.01% -11,068 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 6,451 $84.4K <0.01% 13F-HR Timeline VIRTUS ADVISERS, LLC in group Virtus Investment Advisers, L… More: the full row for VIRTUS ADVISERS, LLC 5,638 $73.8K 0.03% -368 13F-HR Timeline Group Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 3,840 $50.3K <0.01% new 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 3,490 $45.7K <0.01% +637 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 3,421 $44.8K <0.01% +1,132 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 3,325 $43.5K <0.01% -41,785 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 2,413 $31.6K <0.01% +436 13F-HR/A Timeline R Squared Ltd More: the full row for R Squared Ltd 1,670 $21.9K 0.02% 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 1,556 $20.4K <0.01% +16 13F-HR/A Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 1,495 $19.6K <0.01% -88 13F-HR Timeline Group NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 917 $12K <0.01% -27 13F-HR Timeline GPS Wealth Strategies Group, LLC More: the full row for GPS Wealth Strategies Group, LLC 658 $8.61K <0.01% 0 13F-HR Timeline AMALGAMATED BANK More: the full row for AMALGAMATED BANK 581 $8K <0.01% 0 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 548 $7.17K <0.01% 0 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 531 $6.95K <0.01% -1,149 13F-HR Timeline Group BFSG, LLC More: the full row for BFSG, LLC 300 $3.93K <0.01% 0 13F-HR Timeline SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 184 $2K <0.01% new 13F-HR Timeline GeoWealth Management, LLC More: the full row for GeoWealth Management, LLC 148 $1.94K <0.01% new 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 99 $1.3K <0.01% 0 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 38 $497 <0.01% +10 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 14 $183 <0.01% 0 13F-HR Timeline Group ROTHSCHILD INVESTMENT LLC More: the full row for ROTHSCHILD INVESTMENT LLC 10 $131 <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 9 $118 <0.01% new 13F-HR Timeline Group IFP Advisors, Inc More: the full row for IFP Advisors, Inc 0 $65 <0.01% new 13F-HR Timeline Amount filed as zero, left out of ratios. CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 23 $0 0% +6 13F-HR Timeline Group Value filed as zero, left out of ratios. CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0% 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.