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Disclosery

ALEC ALECTOR INC

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COMMON STOCK (common), issuer CIK 1653087

146 managers (149 13F filers) reported a position in ALEC shares at 2025-09-30, 74,743,145 shares in all. 25 filers opened a position and 12 filers sold out during the quarter.

Managers
146
13F filers
149
New
25
Added
46
Reduced
40
Sold out
12
Shares held by filers
74,743,145

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC15,181,849$44.9M<0.01%+182,96013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.7,197,973$21.3M<0.01%-775,60713F-HRTimelineGroup
RTW INVESTMENTS, LP6,990,806$20.7M0.25%new13F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding6,092,979$18M+53,180Timeline
Merck & Co., Inc.in group Merck & Co., Inc.3,545,719$10.5M4.6%013F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC2,372,985$7.02M0.01%+202,59713F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/2,185,032$6.47M<0.01%-2,690,23213F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,861,258$5.51M<0.01%-120,81013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,734,679$5.13M<0.01%+24,77713F-HRTimelineGroup
Eversept Partners, LP1,488,725$4.41M0.34%-497,34713F-HRTimeline
Euclidean Capital LLC1,307,858$3.87M1.63%013F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC1,230,974$3.64M0.01%-91,90813F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,155,027$3.42M<0.01%+744,22413F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,068,215$3.16M<0.01%+78,46813F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,055,192$3.12M0.05%013F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC1,000,000$2.96M0.27%new13F-HRTimelineGroup
5AM Venture Management, LLC995,841$2.95M1.08%013F-HRTimeline
Vestal Point Capital, LP980,000$2.9M0.13%+3,00813F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.978,204$2.9M<0.01%+444,00413F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC949,150$2.81M<0.01%-305,70013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC873,375$2.59M<0.01%+703,58013F-HR/ATimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding824,579$2.44M+225,440Timeline
DAFNA Capital Management LLC798,351$2.36M0.58%-114,57713F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC760,000$2.25M0.46%-140,00013F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC741,293$2.19M0.01%+224,61313F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co689,524$2.04M<0.01%+41,87113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP633,709$1.88M<0.01%-24,45213F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA628,652$1.86M<0.01%+261,46413F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC609,909$1.81M<0.01%+235,43213F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC524,077$1.55M0.04%+65,21413F-HRTimeline
MEDICI CAPITAL LLC481,974$1.43M1.06%+314,78313F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC471,581$1.4M<0.01%-80,23913F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC438,087$1.3M<0.01%+31,46913F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY434,168$1.29M<0.01%-172,38413F-HR/ATimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC350,231$1.04M<0.01%+326,27913F-HRTimelineGroup
New Leaf Venture Partners, L.L.C.339,569$1.01M2.33%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding308,660$914K+34,084Timeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP295,846$876K<0.01%-87,48513F-HRTimelineGroup
MACKENZIE FINANCIAL CORP283,712$840K<0.01%+9,27013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC274,042$811K<0.01%+259,90713F-HRTimelineGroup
TD Asset Management Inc273,738$810K<0.01%-378,00013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/246,283$729K<0.01%-97,62613F-HR/ATimelineGroup
UBS Group AGin group UBS Group AG230,499$682K<0.01%+188,60613F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp224,484$664K<0.01%-44,38813F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …216,574$641K<0.01%-97,00413F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.192,311$569K<0.01%+16,51013F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.175,866$521K0.02%013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP151,643$449K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO136,385$404K<0.01%+90,89413F-HR/ATimelineGroup
DIADEMA PARTNERS LP136,023$403K0.28%-130,00013F-HRTimeline
Nuveen, LLCin group TIAA133,248$394K<0.01%-22,36513F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC115,000$340K0.01%013F-HRTimeline
RHUMBLINE ADVISERS114,270$338K<0.01%-12,29813F-HRTimeline
STRS OHIO110,400$327K<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…104,824$310K<0.01%+4,45813F-HRTimelineGroup
DekaBank Deutsche Girozentrale100,000$303K<0.01%013F-HRTimeline
SIMPLEX TRADING, LLC100,944$298K0.01%new13F-HRTimeline
Cubist Systematic Strategies, LLC100,067$296K<0.01%+78,24813F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd98,513$292K0.02%+25,17513F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.92,940$275K<0.01%013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC91,236$270K<0.01%-60,66013F-HRTimeline
Utah Retirement Systems72,002$213K<0.01%+20,57213F-HRTimeline
Jasper Ridge Partners, L.P.71,776$212K<0.01%+41,14413F-HRTimeline
Artia Global Partners LP71,029$210K0.04%new13F-HR/ATimeline
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…68,200$202K<0.01%+60,30013F-HRTimeline
HRT FINANCIAL LP60,164$178K<0.01%new13F-HRTimeline
Cannell & Spears LLC59,223$175K<0.01%-2,29013F-HRTimeline
Velan Capital Investment Management LP55,000$163K0.15%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC53,938$160K<0.01%+4,47713F-HRTimelineGroup
IEQ CAPITAL, LLC53,050$157K<0.01%-5,94813F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN52,425$155K<0.01%+1,82413F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/52,380$155K<0.01%013F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC48,666$140K<0.01%-3,03413F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL41,282$122K<0.01%+48713F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding36,042$107K-14,107Timeline
INTECH INVESTMENT MANAGEMENT LLC33,428$98.9K<0.01%-6,48713F-HRTimeline
Persistent Asset Partners Ltd31,240$92.5K0.07%-29,85613F-HR/ATimeline
MetLife Investment Management, LLCin group MetLife Investment Management…28,820$85.3K<0.01%new13F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC28,022$82.9K<0.01%+6,70013F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC26,807$79.3K<0.01%+3,07113F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.26,000$77K<0.01%-12,00013F-HRTimelineGroup
Blackstone Inc.in group Blackstone Inc.25,715$76.1K<0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
CWM, LLCin group CWM, LLC25,169$75K<0.01%-72813F-HRTimelineGroup
Apollon Wealth Management, LLCin group Apollon Wealth Management, LLC25,000$74K<0.01%013F-HRTimelineGroup
Police & Firemen's Retirement System of…23,426$69.3K<0.01%+6,42213F-HRTimeline
GROUP ONE TRADING LLC22,321$66.1K<0.01%new13F-HRTimeline
Graham Capital Management, L.P.21,215$62.8K<0.01%-15813F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC20,481$60.6K<0.01%new13F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH19,000$58K<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS18,269$54.1K<0.01%+6,63513F-HRTimelineGroup
China Universal Asset Management Co., L…17,741$52.5K<0.01%-2,34213F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO16,884$50K<0.01%013F-HRTimelineGroup
Creative Planningin group Creative Planning15,721$46.5K<0.01%new13F-HRTimelineGroup
DLK Investment Management, LLC15,500$45.9K0.02%013F-HRTimeline
ProShare Advisors LLC15,431$45.7K<0.01%-4,64713F-HRTimeline
FNY Investment Advisers, LLC15,000$44K0.01%-5,00013F-HRTimeline
Engineers Gate Manager LP14,493$42.9K<0.01%new13F-HRTimeline
HAMILTON LANE ADVISORS LLC14,402$42.6K0.02%new13F-HRTimeline
DIVERSIFIED TRUST CO14,102$41.7K<0.01%013F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC13,929$41.2K<0.01%-10,69213F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…11,970$36.7K<0.01%new13F-HRTimeline
Belvedere Trading LLC10,486$31K<0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND10,310$30.5K<0.01%013F-HRTimeline
HERSHEY TRUST CO10,286$30.4K<0.01%new13F-HRTimeline
Pinegrove Venture Partners, LLC10,286$30.4K0.1%new13F-HRTimeline
Lexington Partners L.P.10,108$29.9K0.01%new13F-HRTimeline
Texas Yale Capital Corp.10,000$29.6K<0.01%013F-HRTimeline
Point72 (DIFC) Ltd9,807$29K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…8,175$24.2K<0.01%013F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.7,636$22.6K<0.01%+7,57813F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc6,039$17.9K<0.01%-1,35613F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…4,963$14.7K<0.01%new13F-HRTimeline
Sterling Capital Management LLC4,399$13K<0.01%+2,40513F-HRTimeline
NISA INVESTMENT ADVISORS, LLC3,347$9.91K<0.01%013F-HRTimeline
Arax Advisory Partners3,190$9.44K<0.01%new13F-HRTimeline
AMALGAMATED BANK2,540$8K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,514$7.44K<0.01%-10,88513F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.2,178$6.45K<0.01%-25113F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,367$4.05K<0.01%new13F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,188$3.52K<0.01%+93913F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,120$3.17K<0.01%013F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.1,018$3.01K<0.01%new13F-HRTimelineGroup
True Wealth Design, LLC799$2.37K<0.01%-13113F-HRTimeline
Physician Wealth Advisors, Inc.752$2.23K<0.01%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.542$1.6K<0.01%new13F-HRTimelineGroup
Essential Partners LLC530$1.57K<0.01%+8613F-HRTimeline
Clearstead Advisors, LLC453$1.34K<0.01%+13013F-HRTimeline
Fortitude Family Office, LLC439$1.3K<0.01%013F-HRTimeline
Federation des caisses Desjardins du Qu…415$1.23K<0.01%013F-HRTimeline
Rise Advisors, LLC407$1.21K<0.01%013F-HRTimeline
Rialto Wealth Management, LLC403$1.19K<0.01%013F-HRTimeline
Wilmington Savings Fund Society, FSB400$1.18K<0.01%013F-HR/ATimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…370$1.09K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.277$1K<0.01%013F-HRTimelineGroup
MARK SHEPTOFF FINANCIAL PLANNING, LLC300$888<0.01%013F-HRTimeline
Advisory Services Network, LLC271$803<0.01%new13F-HRTimeline
Hughes Financial Services, LLC553$724<0.01%-37613F-HRTimeline
ROTHSCHILD INVESTMENT LLC219$648<0.01%-16113F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/200$592<0.01%013F-HRTimelineGroup
Allworth Financial LP84$249<0.01%-11613F-HRTimeline
IFP Advisors, Inc47$139<0.01%+3813F-HR/ATimeline
NewEdge Advisors, LLC32$95<0.01%013F-HRTimeline
COMERICA BANK21$63<0.01%013F-HRTimeline
SBI Securities Co., Ltd.20$59<0.01%013F-HRTimeline
Truvestments Capital LLC2$6<0.01%013F-HRTimeline
Avion Wealth336$00%new13F-HRTimelineValue filed as zero, left out of ratios.