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Disclosery

ALEC ALECTOR INC

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COMMON STOCK (common), issuer CIK 1653087

129 managers (131 13F filers) reported a position in ALEC shares at 2025-12-31, 84,446,669 shares in all. 21 filers opened a position and 39 filers sold out during the quarter.

Managers
129
13F filers
131
New
21
Added
40
Reduced
41
Sold out
39
Shares held by filers
84,446,669

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TCG Crossover Management, LLC10,000,000$15.6M0.52%new13F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.7,147,766$11.2M<0.01%-50,20713F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding6,961,110$10.9M+868,131Timeline
Foresite Capital Management IV, LLCin group Foresite Capital Management V…3,887,200$6.06M2.64%new13F-HRTimelineGroup
Merck & Co., Inc.in group Merck & Co., Inc.3,545,719$5.53M2%013F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC3,442,449$5.36M0.01%+1,069,46413F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC3,350,000$5.23M0.43%+2,350,00013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management3,265,575$5.09M0.01%new13F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.2,365,151$3.69M<0.01%+1,386,94713F-HRTimelineGroup
FMR LLCin group FMR LLC2,231,171$3.48M<0.01%-12,950,67813F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC2,173,202$3.39M0.01%+942,22813F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC2,082,606$3.25M0.42%+1,322,60613F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,075,220$3.24M<0.01%+213,96213F-HRTimelineGroup
Kynam Capital Management, LP2,000,000$3.12M0.2%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,814,298$2.83M<0.01%+79,61913F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,691,456$2.64M+866,877Timeline
RENAISSANCE TECHNOLOGIES LLC1,543,650$2.41M<0.01%+594,50013F-HRTimeline
MEDICI CAPITAL LLC1,500,520$2.34M2.57%+1,018,54613F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,332,914$2.08M<0.01%+177,88713F-HRTimelineGroup
Euclidean Capital LLC1,307,858$2.04M0.55%013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP1,166,817$1.82M<0.01%+1,015,17413F-HRTimelineGroup
Spruce Street Capital LP1,117,986$1.74M0.58%13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,108,000$1.73M0.13%new13F-HR/ATimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,055,192$1.65M0.02%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,035,154$1.61M<0.01%-33,06113F-HRTimelineGroup
Eversept Partners, LP1,006,163$1.57M0.09%-482,56213F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC993,913$1.55M<0.01%+643,68213F-HRTimelineGroup
DAFNA Capital Management LLC908,351$1.42M0.33%+110,00013F-HRTimeline
Elmind Capital, LP900,000$1.4M0.41%13F-HRTimeline
PANAGORA ASSET MANAGEMENT INC850,298$1.33M<0.01%+109,00513F-HRTimeline
Vestal Point Capital, LP755,000$1.18M0.04%-225,00013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co665,491$1.04M<0.01%-24,03313F-HRTimelineGroup
MACKENZIE FINANCIAL CORP660,168$1M<0.01%+376,45613F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC599,569$935K<0.01%+161,48213F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd592,839$925K0.02%+494,32613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP587,653$917K<0.01%-46,05613F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC559,726$873K0.02%+35,64913F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC437,959$683K<0.01%-171,95013F-HR/ATimelineGroup
DekaBank Deutsche Girozentrale100,000$661K<0.01%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC398,687$622K<0.01%-474,68813F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC354,299$553K<0.01%+80,25713F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY319,072$498K<0.01%-115,09613F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…291,180$454K<0.01%-17,48013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.279,468$436K<0.01%+87,15713F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP225,566$352K0.03%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp217,862$340K<0.01%-6,62213F-HRTimelineGroup
NANO CAP NEW MILLENNIUM GROWTH FUND L P200,000$312K0.27%13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP199,126$310K<0.01%-96,72013F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD172,300$269K<0.01%new13F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…136,000$212K<0.01%+67,80013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/134,506$210K<0.01%-111,77713F-HRTimelineGroup
Utah Retirement Systems133,718$209K<0.01%+61,71613F-HRTimeline
Nuveen, LLCin group TIAA133,248$208K<0.01%013F-HRTimelineGroup
UBS Group AGin group UBS Group AG119,411$186K<0.01%-111,08813F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC115,000$179K<0.01%013F-HRTimeline
STRS OHIO110,400$172K<0.01%013F-HRTimeline
Graham Capital Management, L.P.104,851$164K0.01%+83,63613F-HRTimeline
RHUMBLINE ADVISERS101,926$159K<0.01%-12,34413F-HRTimeline
Jasper Ridge Partners, L.P.95,068$148K<0.01%+23,29213F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC93,547$146K<0.01%-378,03413F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.92,940$145K<0.01%013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC93,052$141K<0.01%+1,81613F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN90,108$141K<0.01%+37,68313F-HRTimelineGroup
Man Group plcin group Man Group plc86,162$134K<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC82,017$128K<0.01%-18,92713F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC77,618$121K<0.01%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…71,887$112K<0.01%-32,93713F-HRTimelineGroup
Blackstone Inc.in group Blackstone Inc.66,859$104K<0.01%+41,14413F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Quadrature Capital Ltdin group Quadrature Capital Ltd62,273$97.1K<0.01%new13F-HRTimelineGroup
HRT FINANCIAL LP57,341$89K<0.01%-2,82313F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/56,203$89K<0.01%-2,128,82913F-HRTimeline
Cannell & Spears LLC54,642$85.2K<0.01%-4,58113F-HRTimeline
Lexington Partners L.P.53,488$83.4K0.02%+43,38013F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC48,521$75.7K<0.01%-14513F-HR/ATimelineGroup
OXFORD ASSET MANAGEMENT LLP42,905$66.9K0.02%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
TUDOR INVESTMENT CORP ET AL41,282$64.4K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…39,520$61.7K<0.01%+37,00613F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding37,271$58.1K+1,229Timeline
INTECH INVESTMENT MANAGEMENT LLC34,510$53.8K<0.01%+1,08213F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO32,623$50.9K<0.01%-103,76213F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC32,225$50.3K<0.01%+4,20313F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.30,000$46.8K<0.01%+4,00013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …28,829$45K<0.01%-187,74513F-HRTimelineGroup
SG Americas Securities, LLC27,002$42K<0.01%new13F-HRTimeline
Dynamic Technology Lab Private Ltd25,881$40K0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…23,426$36.5K<0.01%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.23,102$36K<0.01%+22,56013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS22,385$34.9K<0.01%+4,11613F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC21,886$34K<0.01%new13F-HRTimelineGroup
HERSHEY TRUST CO20,572$32.1K<0.01%+10,28613F-HRTimeline
Bronte Capital Management Pty Ltd.19,282$30.1K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO16,884$26.3K<0.01%013F-HRTimelineGroup
ProShare Advisors LLC14,672$22.9K<0.01%-75913F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC14,173$22.1K<0.01%new13F-HRTimelineGroup
DIVERSIFIED TRUST CO14,102$22K<0.01%013F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC13,929$21.7K<0.01%013F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC13,682$21.3K<0.01%-13,12513F-HRTimelineGroup
R Squared Ltd12,474$19.5K0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC12,164$19K<0.01%-13,00513F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND10,310$16.1K<0.01%013F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP10,288$16K<0.01%new13F-HR/ATimelineGroup
HighTower Advisors, LLC10,011$15.6K<0.01%new13F-HRTimeline
Texas Yale Capital Corp.10,000$15.6K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…8,175$12.8K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC6,155$9.6K<0.01%-47,78313F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc6,039$9.42K<0.01%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…4,940$7.71K<0.01%-2313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,678$7K<0.01%-623,97413F-HRTimelineGroup
Sterling Capital Management LLC4,421$6.9K<0.01%+2213F-HRTimeline
AMALGAMATED BANK2,523$4K<0.01%-1713F-HRTimeline
GAMMA Investing LLC1,075$1.68K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC1,016$1.58K<0.01%-2,33113F-HRTimeline
Physician Wealth Advisors, Inc.752$1.17K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.620$967<0.01%-50013F-HRTimelineGroup
True Wealth Design, LLC563$879<0.01%-23613F-HRTimeline
Hughes Financial Services, LLC553$863<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…504$786<0.01%-68413F-HRTimelineGroup
Essential Partners LLC431$672<0.01%-9913F-HRTimeline
Federation des caisses Desjardins du Qu…415$647<0.01%013F-HRTimeline
Wilmington Savings Fund Society, FSB400$624<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…367$573<0.01%-1,00013F-HR/ATimelineGroup
Basecamp Wealth Advisors LLC329$513<0.01%13F-HRTimeline
MARK SHEPTOFF FINANCIAL PLANNING, LLC300$468<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC209$326<0.01%-1013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/200$312<0.01%013F-HRTimelineGroup
Kingdom Financial Group LLC.48$75<0.01%new13F-HRTimeline
IFP Advisors, Inc47$73<0.01%013F-HRTimeline
SBI Securities Co., Ltd.20$31<0.01%013F-HRTimeline
COMERICA BANK9$14<0.01%-1213F-HRTimeline