TCG Crossover Management, LLC More: the full row for TCG Crossover Management, LLC 6,056,596 $37.9M 5.16% 0 13F-HR Timeline Deep Track Capital, LP More: the full row for Deep Track Capital, LP 3,579,209 $22.4M 0.72% 0 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 2,210,019 $13.8M 2.66% +696,626 13F-HR Timeline Group Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 2,130,000 $13.3M 1.01% 0 13F-HR Timeline GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 1,638,111 $10.2M 5.57% -10,412 13F-HR Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 1,482,994 $9.27M 0.77% +46,947 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 1,373,860 $8.59M 0.01% +518,184 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 1,371,050 $8.57M <0.01% -95,012 13F-HR Timeline Group Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 1,345,780 $8.41M 0.72% 0 13F-HR Timeline Caligan Partners LP More: the full row for Caligan Partners LP 1,269,119 $7.93M 1.66% +516,952 13F-HR Timeline Octagon Capital Advisors LP More: the full row for Octagon Capital Advisors LP 1,230,000 $7.69M 1.51% new 13F-HR/A Timeline Allostery Investments LP More: the full row for Allostery Investments LP 1,099,654 $6.87M 9.91% +508,401 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 987,414 $6.17M 0.01% +56,235 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 907,679 $5.67M <0.01% +178,760 13F-HR Timeline Group Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 710,516 $4.44M 0.01% +286,335 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 570,668 $3.57M 0.13% +163,765 13F-HR Timeline Saturn V Capital Management LP More: the full row for Saturn V Capital Management LP 552,926 $3.46M 1.74% -100,145 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 497,153 $3.11M <0.01% +17,827 13F-HR Timeline Group Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 455,684 $2.85M 0.01% new 13F-HR Timeline SAMSARA BIOCAPITAL, LLC More: the full row for SAMSARA BIOCAPITAL, LLC 425,000 $2.66M 0.47% -425,000 13F-HR Timeline KENNEDY CAPITAL MANAGEMENT LLC More: the full row for KENNEDY CAPITAL MANAGEMENT LLC 225,191 $1.41M 0.03% -279 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 220,845 $1.38M 0.02% -81,797 13F-HR Timeline Group SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 210,901 $1.32M 0.28% -74,219 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 201,924 $1.26M 0.01% +153,788 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 200,000 $1.25M 0.2% new 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 184,239 $1.15M <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 162,554 $1.02M <0.01% -12,319 13F-HR Timeline Group Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 125,000 $781K 0.06% 0 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 74,841 $468K <0.01% new 13F-HR Timeline Group Shay Capital LLC More: the full row for Shay Capital LLC 52,829 $330K 0.1% +2,800 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 49,064 $307K 0.12% 0 13F-HR Timeline Paloma Partners Management Co in group Paloma Partners Management Co More: the full row for Paloma Partners Management Co 38,449 $240K 0.04% new 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 29,418 $184K <0.01% -61,882 13F-HR/A Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 19,000 $119K <0.01% +7,332 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 16,749 $105K <0.01% 0 13F-HR Timeline Group GUGGENHEIM CAPITAL LLC in group GUGGENHEIM CAPITAL LLC More: the full row for GUGGENHEIM CAPITAL LLC 13,792 $86.2K <0.01% +1,280 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 11,446 $71.5K <0.01% -7,798 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 10,706 $66.9K <0.01% +5,170 13F-HR Timeline Group Cubist Systematic Strategies, LLC More: the full row for Cubist Systematic Strategies, LLC 10,152 $63.5K <0.01% +2,595 13F-HR Timeline Hurley Capital, LLC More: the full row for Hurley Capital, LLC 3,015 $18.8K 0.01% new 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 3,013 $18.8K <0.01% -963 13F-HR/A Timeline Covestor Ltd More: the full row for Covestor Ltd 2,660 $17K 0.01% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 1,478 $9.24K <0.01% +383 13F-HR/A Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 738 $4.61K <0.01% +32 13F-HR/A Timeline Financial Management Professionals, Inc. More: the full row for Financial Management Professionals, Inc. 100 $625 <0.01% 0 13F-HR Timeline PRINCIPAL SECURITIES, INC. in group PRINCIPAL FINANCIAL GROUP INC More: the full row for PRINCIPAL SECURITIES, INC. 10 $73 <0.01% 0 13F-HR Timeline Group CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.