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NOVO HOLDINGS A/S

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13F filer, CIK 1388325, HELLERUP, Denmark

NOVO HOLDINGS A/S reported $1,551,582,935 across 27 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 73.16% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001388325-25-000025

Period
2025-09-30
Reported value
$1.55B
Holdings
27
Top 10 weight
73.16%
New
2
Sold out
4

Largest buys vs the previous quarter

SecurityShares changeApprox. value
BBOTnew+1,961,317$22.7M
ELVNadded+341,828$7M
LNZAnew+158,148$3.88M
CRNXadded+75,000$3.12M
APGEadded+50,608$2.01M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
INSMreduced-480,000-$69.1M
BLUEPRINT MEDICINES CORPexited-264,956-$34M
BABAreduced-115,000-$20.6M
ASMLreduced-20,000-$19.4M
MIRMreduced-236,027-$17.3M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001388325-25-000025, largest first. % of portfolio is the value over $1,551,582,935, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
VTIVANGUARD INDEX FDSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,038,550 shares; 2024Q4: 1,038,550 shares; 2025Q1: 1,038,550 shares; 2025Q2: 1,038,550 shares; 2025Q3: 1,038,550 shares 1,038,550$341M21.97%0Timeline
BNBROOKFIELD CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,491,230 shares; 2024Q4: 2,798,830 shares; 2025Q1: 2,330,830 shares; 2025Q2: 2,330,830 shares; 2025Q3: 2,330,830 shares 2,330,830$160M10.3%0Timeline
ASMLASML HLDG NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 133,336 shares; 2024Q4: 165,836 shares; 2025Q1: 165,836 shares; 2025Q2: 165,836 shares; 2025Q3: 145,836 shares 145,836$141M9.1%-20,000Timeline
MIRMMIRUM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,500,000 shares; 2024Q4: 1,500,000 shares; 2025Q1: 1,500,000 shares; 2025Q2: 1,500,055 shares; 2025Q3: 1,264,028 shares 1,264,028$92.7M5.97%-236,027Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,549,900 shares; 2024Q4: 5,000,000 shares; 2025Q1: 5,350,000 shares; 2025Q2: 5,350,000 shares; 2025Q3: 5,350,000 shares 5,350,000$86.8M5.59%0Timeline
CRMSALESFORCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 368,560 shares; 2024Q4: 293,901 shares; 2025Q1: 272,801 shares; 2025Q2: 330,187 shares; 2025Q3: 330,187 shares 330,187$78.3M5.04%0Timeline
MERUS N VMERUS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 700,000 shares; 2024Q4: 750,000 shares; 2025Q1: 789,129 shares; 2025Q2: 750,000 shares; 2025Q3: 750,000 shares 750,000$70.6M4.55%0
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,000,000 shares; 2024Q4: 960,215 shares; 2025Q1: 1,275,000 shares; 2025Q2: 1,550,000 shares; 2025Q3: 1,625,000 shares 1,625,000$67.7M4.36%+75,000Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,385,000 shares; 2024Q4: 2,250,000 shares; 2025Q1: 2,250,300 shares; 2025Q2: 2,380,000 shares; 2025Q3: 2,380,000 shares 2,380,000$51.4M3.31%0Timeline
BABAALIBABA GROUP HLDG LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 500,827 shares; 2024Q4: 452,327 shares; 2025Q1: 372,327 shares; 2025Q2: 372,327 shares; 2025Q3: 257,327 shares 257,327$46M2.96%-115,000Timeline
ZBIOZENAS BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,150,000 shares; 2024Q4: 1,600,000 shares; 2025Q1: 2,214,967 shares; 2025Q2: 2,250,000 shares; 2025Q3: 2,000,000 shares 2,000,000$44.4M2.86%-250,000Timeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,725,000 shares; 2024Q4: 1,725,000 shares; 2025Q1: 1,725,000 shares; 2025Q2: 1,725,000 shares; 2025Q3: 1,750,000 shares 1,750,000$43.7M2.81%+25,000Timeline
RXRXRECURSION PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 10,114,633 shares; 2025Q1: 9,665,128 shares; 2025Q2: 9,665,128 shares; 2025Q3: 7,929,835 shares 7,929,835$38.7M2.49%-1,735,293Timeline
AVBPARRIVENT BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,505,315 shares; 2024Q4: 1,520,627 shares; 2025Q1: 1,872,142 shares; 2025Q2: 1,872,142 shares; 2025Q3: 1,942,142 shares 1,942,142$35.8M2.31%+70,000Timeline
BMRNBIOMARIN PHARMACEUTICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 490,000 shares; 2024Q4: 490,000 shares; 2025Q1: 490,000 shares; 2025Q2: 660,000 shares; 2025Q3: 660,000 shares 660,000$35.7M2.3%0Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 750,000 shares; 2024Q4: 750,000 shares; 2025Q1: 915,000 shares; 2025Q2: 916,160 shares; 2025Q3: 916,160 shares 916,160$33M2.13%0Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 963,663 shares; 2024Q4: 1,000,000 shares; 2025Q1: 1,200,000 shares; 2025Q2: 1,200,000 shares; 2025Q3: 1,200,000 shares 1,200,000$31M2%0Timeline
ELVNENLIVEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,084,432 shares; 2025Q3: 1,426,260 shares 1,426,260$29.2M1.88%+341,828Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 724,666 shares; 2024Q4: 724,666 shares; 2025Q1: 724,666 shares; 2025Q2: 680,000 shares; 2025Q3: 200,000 shares 200,000$28.8M1.86%-480,000Timeline
VALNVALNEVA SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 2,375,000 shares; 2025Q3: 2,345,000 shares 2,345,000$28.6M1.84%-30,000Timeline
BBOTBRIDGEBIO ONCOLOGY THERAPEUTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,961,317 shares 1,961,317$22.7M1.46%newTimeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 449,392 shares; 2025Q3: 500,000 shares 500,000$19.9M1.28%+50,608Timeline
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,500,000 shares; 2024Q4: 1,500,000 shares; 2025Q1: 1,950,000 shares; 2025Q2: 2,000,000 shares; 2025Q3: 2,000,000 shares 2,000,000$17.4M1.12%0Timeline
LNZALANZATECH GLOBAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 158,148 shares 158,148$3.88M0.25%newTimeline
MQMARQETA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 441,558 shares; 2024Q4: 441,558 shares; 2025Q1: 441,558 shares; 2025Q2: 441,558 shares; 2025Q3: 441,558 shares 441,558$2.33M0.15%0Timeline
IOBTQIO BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,354,449 shares; 2024Q4: 3,354,449 shares; 2025Q1: 3,354,449 shares; 2025Q2: 3,354,449 shares; 2025Q3: 2,512,453 shares 2,512,453$912K0.06%-841,996Timeline
DMRADAMORA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 99,913 shares; 2024Q4: 99,913 shares; 2025Q1: 99,913 shares; 2025Q2: 99,913 shares; 2025Q3: 86,579 shares 86,579$322K0.02%-13,334Timeline

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
BLUEPRINT MEDICINES CORPBLUEPRINT MEDICINES CORP264,956$34Mshares
CBLLCERIBELL INC900,000$16.9Mshares
LANZATECH GLOBAL INCLANZATECH GLOBAL INC15,814,845$4.29Mshares
ABCLABCELLERA BIOLOGICS INC652,529$2.24Mshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001388325-25-000025 base2025-11-14acceptance time not in the bulk data set