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NEA Management Company, LLC

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13F filer, CIK 1512848, TIMONIUM, MD

NEA Management Company, LLC reported $1,961,136,508 across 27 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 86.5% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001072613-26-000191

Period
2025-12-31
Reported value
$1.96B
Holdings
27
Top 10 weight
86.5%
New
1
Sold out
3

Largest buys vs the previous quarter

SecurityShares changeApprox. value
CELCadded+1,391,300$139M
ZBIOadded+789,500$28.7M
X4 PHARMACEUTICALS INCadded+1,000,000$4M
LONAnew+464,398$3.52M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
VERONA PHARMA PLCexited-2,252,994-$240M
NEUEHEALTH INCexited-2,726,917-$18.2M
OMDAexited-364,115-$8.05M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001072613-26-000191, largest first. % of portfolio is the value over $1,961,136,508, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,250,001 shares; 2024Q4: 1,250,001 shares; 2025Q1: 1,250,001 shares; 2025Q2: 2,294,261 shares; 2025Q3: 2,144,261 shares; 2025Q4: 3,535,561 shares 3,535,561$353M17.98%+1,391,300Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,909,956 shares; 2024Q4: 2,909,956 shares; 2025Q1: 2,909,956 shares; 2025Q2: 2,909,956 shares; 2025Q3: 2,909,956 shares; 2025Q4: 2,909,956 shares 2,909,956$311M15.88%0Timeline
ACLXARCELLX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,745,262 shares; 2024Q4: 3,745,262 shares; 2025Q1: 3,745,262 shares; 2025Q2: 3,745,262 shares; 2025Q3: 3,045,262 shares; 2025Q4: 3,045,262 shares 3,045,262$199M10.12%0Timeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 11,370,376 shares; 2024Q4: 11,370,376 shares; 2025Q1: 11,370,376 shares; 2025Q2: 13,222,228 shares; 2025Q3: 13,222,228 shares; 2025Q4: 13,222,228 shares 13,222,228$166M8.44%0Timeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 24,471,264 shares; 2024Q4: 24,471,264 shares; 2025Q1: 24,471,264 shares; 2025Q2: 24,471,264 shares; 2025Q3: 24,471,264 shares; 2025Q4: 24,471,264 shares 24,471,264$148M7.52%0Timeline
ZBIOZENAS BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,613,948 shares; 2024Q4: 2,613,948 shares; 2025Q1: 2,613,948 shares; 2025Q2: 2,733,719 shares; 2025Q3: 2,733,719 shares; 2025Q4: 3,523,219 shares 3,523,219$128M6.52%+789,500Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,692,298 shares; 2024Q4: 7,692,298 shares; 2025Q1: 7,692,298 shares; 2025Q2: 7,692,298 shares; 2025Q3: 7,692,298 shares; 2025Q4: 7,692,298 shares 7,692,298$121M6.15%0Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,614,486 shares; 2024Q4: 3,614,486 shares; 2025Q1: 3,614,486 shares; 2025Q2: 3,614,486 shares; 2025Q3: 3,614,486 shares; 2025Q4: 3,614,486 shares 3,614,486$114M5.81%0Timeline
COURCOURSERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 12,867,769 shares; 2024Q4: 12,867,769 shares; 2025Q1: 12,867,769 shares; 2025Q2: 12,867,769 shares; 2025Q3: 12,867,769 shares; 2025Q4: 12,867,769 shares 12,867,769$94.7M4.83%0Timeline
AUPHAURINIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,969,834 shares; 2024Q4: 3,969,834 shares; 2025Q1: 3,969,834 shares; 2025Q2: 3,969,834 shares; 2025Q3: 3,969,834 shares; 2025Q4: 3,969,834 shares 3,969,834$63.3M3.23%0Timeline
GOSSGOSSAMER BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 18,093,034 shares; 2024Q4: 18,093,034 shares; 2025Q1: 18,093,034 shares; 2025Q2: 18,093,034 shares; 2025Q3: 18,093,034 shares; 2025Q4: 18,093,034 shares 18,093,034$56.1M2.86%0Timeline
CRSPCRISPR THERAPEUTICS AGQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,587,854 shares; 2024Q4: 1,587,854 shares; 2025Q1: 1,587,854 shares; 2025Q2: 1,587,854 shares; 2025Q3: 1,058,570 shares; 2025Q4: 1,058,570 shares 1,058,570$55.5M2.83%0Timeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,500,000 shares; 2024Q4: 1,566,081 shares; 2025Q1: 2,195,545 shares; 2025Q2: 4,118,621 shares; 2025Q3: 4,118,621 shares; 2025Q4: 4,118,621 shares 4,118,621$33.7M1.72%0Timeline
PHATPHATHOM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,960,169 shares; 2024Q4: 1,960,169 shares; 2025Q1: 1,960,169 shares; 2025Q2: 1,960,169 shares; 2025Q3: 1,960,169 shares; 2025Q4: 1,960,169 shares 1,960,169$32.5M1.66%0Timeline
CVRXCVRX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,370,542 shares; 2024Q4: 2,026,083 shares; 2025Q1: 2,026,083 shares; 2025Q2: 2,026,083 shares; 2025Q3: 2,026,083 shares; 2025Q4: 2,026,083 shares 2,026,083$14.4M0.73%0Timeline
X4 PHARMACEUTICALS INCX4 PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,986,793 shares; 2024Q4: 14,986,793 shares; 2025Q1: 14,986,793 shares; 2025Q2: 499,559 shares; 2025Q3: 2,233,743 shares; 2025Q4: 3,233,743 shares 3,233,743$12.9M0.66%+1,000,000
CSBRCHAMPIONS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,713,720 shares; 2024Q4: 1,713,720 shares; 2025Q1: 1,713,720 shares; 2025Q2: 1,713,720 shares; 2025Q3: 1,713,720 shares; 2025Q4: 1,713,720 shares 1,713,720$11.8M0.6%0Timeline
BDTXBLACK DIAMOND THERAPEUTICS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,448,757 shares; 2024Q4: 4,448,757 shares; 2025Q1: 4,448,757 shares; 2025Q2: 4,448,757 shares; 2025Q3: 4,448,757 shares; 2025Q4: 4,448,757 shares 4,448,757$10.8M0.55%0Timeline
KRROKORRO BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,090,793 shares; 2024Q4: 1,090,793 shares; 2025Q1: 1,090,793 shares; 2025Q2: 1,090,793 shares; 2025Q3: 1,090,793 shares; 2025Q4: 1,090,793 shares 1,090,793$8.74M0.45%0Timeline
IVAINVENTIVA SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,462,586 shares; 2024Q4: 1,462,586 shares; 2025Q1: 1,462,586 shares; 2025Q2: 1,462,586 shares; 2025Q3: 1,462,586 shares; 2025Q4: 1,462,586 shares 1,462,586$6.8M0.35%0Timeline
NKTXNKARTA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,568,781 shares; 2024Q4: 3,568,781 shares; 2025Q1: 3,568,781 shares; 2025Q2: 3,568,781 shares; 2025Q3: 3,568,781 shares; 2025Q4: 3,568,781 shares 3,568,781$6.6M0.34%0Timeline
SNTISENTI BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 442,615 shares; 2024Q4: 442,615 shares; 2025Q1: 3,775,615 shares; 2025Q2: 3,775,615 shares; 2025Q3: 3,775,615 shares; 2025Q4: 3,775,615 shares 3,775,615$3.93M0.2%0Timeline
LONALEONABIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 464,398 shares 464,398$3.52M0.18%newTimeline
SYBXSYNLOGIC INC COM NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,922,772 shares; 2024Q4: 2,922,772 shares; 2025Q1: 2,922,772 shares; 2025Q2: 2,922,772 shares; 2025Q3: 2,922,772 shares; 2025Q4: 2,922,772 shares 2,922,772$3.27M0.17%0Timeline
MRKRMARKER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,071,428 shares; 2024Q4: 1,625,678 shares; 2025Q1: 1,625,678 shares; 2025Q2: 1,625,678 shares; 2025Q3: 1,625,678 shares; 2025Q4: 1,625,678 shares 1,625,678$2.42M0.12%0Timeline
OKURONKURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 478,548 shares; 2025Q1: 478,548 shares; 2025Q2: 478,548 shares; 2025Q3: 478,548 shares; 2025Q4: 478,548 shares 478,548$1.39M0.07%0Timeline
IMAIMAGENEBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 50,005 shares; 2025Q4: 50,005 shares 50,005$345K0.02%0Timeline

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
VERONA PHARMA PLCVERONA PHARMA PLC2,252,994$240Mshares
NEUEHEALTH INCNEUEHEALTH INC2,726,917$18.2Mshares
OMDAOMADA HEALTH INC364,115$8.05Mshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001072613-26-000191 base2026-02-17acceptance time not in the bulk data set