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NEA Management Company, LLC

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13F filer, CIK 1512848, TIMONIUM, MD

NEA Management Company, LLC reported $1,822,265,067 across 29 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 79.12% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0000897069-25-001705

Period
2025-09-30
Reported value
$1.82B
Holdings
29
Top 10 weight
79.12%
New
1
Sold out
4

Largest buys vs the previous quarter

SecurityShares changeApprox. value
X4 PHARMACEUTICALS INCadded+1,734,184$5.93M
IMAnew+50,005$408K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
ACLXreduced-700,000-$57.5M
CRSPreduced-529,284-$34.3M
INOZYME PHARMA INCexited-2,437,689-$9.75M
CELCreduced-150,000-$7.41M
ADAPYexited-17,079,778-$4.09M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0000897069-25-001705, largest first. % of portfolio is the value over $1,822,265,067, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,909,956 shares; 2024Q4: 2,909,956 shares; 2025Q1: 2,909,956 shares; 2025Q2: 2,909,956 shares; 2025Q3: 2,909,956 shares 2,909,956$294M16.13%0Timeline
ACLXARCELLX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,745,262 shares; 2024Q4: 3,745,262 shares; 2025Q1: 3,745,262 shares; 2025Q2: 3,745,262 shares; 2025Q3: 3,045,262 shares 3,045,262$250M13.72%-700,000Timeline
VERONA PHARMA PLCVERONA PHARMA PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,584,753 shares; 2024Q4: 5,584,753 shares; 2025Q1: 2,688,565 shares; 2025Q2: 2,263,138 shares; 2025Q3: 2,252,994 shares 2,252,994$240M13.19%-10,144
COURCOURSERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 12,867,769 shares; 2024Q4: 12,867,769 shares; 2025Q1: 12,867,769 shares; 2025Q2: 12,867,769 shares; 2025Q3: 12,867,769 shares 12,867,769$151M8.27%0Timeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 11,370,376 shares; 2024Q4: 11,370,376 shares; 2025Q1: 11,370,376 shares; 2025Q2: 13,222,228 shares; 2025Q3: 13,222,228 shares 13,222,228$121M6.64%0Timeline
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,250,001 shares; 2024Q4: 1,250,001 shares; 2025Q1: 1,250,001 shares; 2025Q2: 2,294,261 shares; 2025Q3: 2,144,261 shares 2,144,261$106M5.81%-150,000Timeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 24,471,264 shares; 2024Q4: 24,471,264 shares; 2025Q1: 24,471,264 shares; 2025Q2: 24,471,264 shares; 2025Q3: 24,471,264 shares 24,471,264$87.4M4.79%0Timeline
CRSPCRISPR THERAPEUTICS AGQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,587,854 shares; 2024Q4: 1,587,854 shares; 2025Q1: 1,587,854 shares; 2025Q2: 1,587,854 shares; 2025Q3: 1,058,570 shares 1,058,570$68.6M3.76%-529,284Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,614,486 shares; 2024Q4: 3,614,486 shares; 2025Q1: 3,614,486 shares; 2025Q2: 3,614,486 shares; 2025Q3: 3,614,486 shares 3,614,486$63.3M3.47%0Timeline
ZBIOZENAS BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,613,948 shares; 2024Q4: 2,613,948 shares; 2025Q1: 2,613,948 shares; 2025Q2: 2,733,719 shares; 2025Q3: 2,733,719 shares 2,733,719$60.7M3.33%0Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,692,298 shares; 2024Q4: 7,692,298 shares; 2025Q1: 7,692,298 shares; 2025Q2: 7,692,298 shares; 2025Q3: 7,692,298 shares 7,692,298$57M3.13%0Timeline
KRROKORRO BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,090,793 shares; 2024Q4: 1,090,793 shares; 2025Q1: 1,090,793 shares; 2025Q2: 1,090,793 shares; 2025Q3: 1,090,793 shares 1,090,793$52.2M2.87%0Timeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,500,000 shares; 2024Q4: 1,566,081 shares; 2025Q1: 2,195,545 shares; 2025Q2: 4,118,621 shares; 2025Q3: 4,118,621 shares 4,118,621$49.4M2.71%0Timeline
GOSSGOSSAMER BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 18,093,034 shares; 2024Q4: 18,093,034 shares; 2025Q1: 18,093,034 shares; 2025Q2: 18,093,034 shares; 2025Q3: 18,093,034 shares 18,093,034$47.6M2.61%0Timeline
AUPHAURINIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,969,834 shares; 2024Q4: 3,969,834 shares; 2025Q1: 3,969,834 shares; 2025Q2: 3,969,834 shares; 2025Q3: 3,969,834 shares 3,969,834$43.9M2.41%0Timeline
PHATPHATHOM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,960,169 shares; 2024Q4: 1,960,169 shares; 2025Q1: 1,960,169 shares; 2025Q2: 1,960,169 shares; 2025Q3: 1,960,169 shares 1,960,169$23.1M1.27%0Timeline
NEUEHEALTH INCNEUEHEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,726,917 shares; 2024Q4: 2,726,917 shares; 2025Q1: 2,726,917 shares; 2025Q2: 2,726,917 shares; 2025Q3: 2,726,917 shares 2,726,917$18.2M1%0
BDTXBLACK DIAMOND THERAPEUTICS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,448,757 shares; 2024Q4: 4,448,757 shares; 2025Q1: 4,448,757 shares; 2025Q2: 4,448,757 shares; 2025Q3: 4,448,757 shares 4,448,757$16.9M0.93%0Timeline
CVRXCVRX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,370,542 shares; 2024Q4: 2,026,083 shares; 2025Q1: 2,026,083 shares; 2025Q2: 2,026,083 shares; 2025Q3: 2,026,083 shares 2,026,083$16.4M0.9%0Timeline
CSBRCHAMPIONS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,713,720 shares; 2024Q4: 1,713,720 shares; 2025Q1: 1,713,720 shares; 2025Q2: 1,713,720 shares; 2025Q3: 1,713,720 shares 1,713,720$11.1M0.61%0Timeline
IVAINVENTIVA SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,462,586 shares; 2024Q4: 1,462,586 shares; 2025Q1: 1,462,586 shares; 2025Q2: 1,462,586 shares; 2025Q3: 1,462,586 shares 1,462,586$8.32M0.46%0Timeline
OMDAOMADA HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 364,115 shares; 2025Q3: 364,115 shares 364,115$8.05M0.44%0Timeline
X4 PHARMACEUTICALS INCX4 PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,986,793 shares; 2024Q4: 14,986,793 shares; 2025Q1: 14,986,793 shares; 2025Q2: 499,559 shares; 2025Q3: 2,233,743 shares 2,233,743$7.64M0.42%+1,734,184
NKTXNKARTA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,568,781 shares; 2024Q4: 3,568,781 shares; 2025Q1: 3,568,781 shares; 2025Q2: 3,568,781 shares; 2025Q3: 3,568,781 shares 3,568,781$7.39M0.41%0Timeline
SNTISENTI BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 442,615 shares; 2024Q4: 442,615 shares; 2025Q1: 3,775,615 shares; 2025Q2: 3,775,615 shares; 2025Q3: 3,775,615 shares 3,775,615$5.32M0.29%0Timeline
SYBXSYNLOGIC INC COM NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,922,772 shares; 2024Q4: 2,922,772 shares; 2025Q1: 2,922,772 shares; 2025Q2: 2,922,772 shares; 2025Q3: 2,922,772 shares 2,922,772$4.88M0.27%0Timeline
MRKRMARKER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,071,428 shares; 2024Q4: 1,625,678 shares; 2025Q1: 1,625,678 shares; 2025Q2: 1,625,678 shares; 2025Q3: 1,625,678 shares 1,625,678$1.45M0.08%0Timeline
OKURONKURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 478,548 shares; 2025Q1: 478,548 shares; 2025Q2: 478,548 shares; 2025Q3: 478,548 shares 478,548$1.32M0.07%0Timeline
IMAIMAGENEBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 50,005 shares 50,005$408K0.02%newTimeline

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
INOZYME PHARMA INCINOZYME PHARMA INC2,437,689$9.75Mshares
ADAPYADAPTIMMUNE THERAPEUTICS PLC S17,079,778$4.09Mshares
IKENA ONCOLOGY INCIKENA ONCOLOGY INC600,063$804Kshares
UPWHEELS UP EXPERIENCE INC106,125$114Kshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0000897069-25-001705 base2025-11-14acceptance time not in the bulk data set