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Foresite Capital Management V, LLC

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13F filer, CIK 1792206, WEST HOLLYWOOD, CA

Foresite Capital Management V, LLC reported $270,996,711 across 9 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-062464

Period
2026-03-31
Reported value
$271M
Holdings
9
Top 10 weight
100%
New
3
Sold out
1

Part of the filer group Foresite Capital Management VI LLC

How groups are built

Stakes and trades reported after 2026-03-31

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • IRLA QUINCE THERAPEUTICS INC: 13G 652,039 shares, 6% of the class, 13G filed 2026-10-14, 0001104659-26-115859Timeline
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
EIKNnew+1,318,983$14M
HIMSadded+465,000$9.65M
PHVSnew+194,125$5.48M
IRONadded+75,000$4.8M
NRIXnew+265,000$4.11M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
NTRAexited-67,356-$15.4M
MAZEreduced-60,386-$1.8M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001104659-26-062464, largest first. % of portfolio is the value over $270,996,711, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 5,584,889 shares; 2024Q4: 5,779,348 shares; 2025Q1: 5,779,348 shares; 2025Q2: 5,779,348 shares; 2025Q3: 5,779,348 shares; 2025Q4: 5,779,348 shares; 2026Q1: 5,896,995 shares 5,896,995$130M47.94%+117,647Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 692,550 shares; 2024Q4: 692,550 shares; 2025Q1: 859,050 shares; 2025Q2: 1,004,050 shares; 2025Q3: 1,004,050 shares; 2025Q4: 1,004,050 shares; 2026Q1: 1,004,050 shares 1,004,050$68M25.08%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 299,069 shares; 2024Q4: 299,069 shares; 2025Q1: 299,069 shares; 2025Q2: 299,069 shares; 2025Q3: 299,069 shares; 2025Q4: 299,069 shares; 2026Q1: 374,069 shares 374,069$23.9M8.83%+75,000Timeline
HIMSHIMS & HERS HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,759,314 shares; 2024Q4: 939,860 shares; 2025Q1: 273,151 shares; 2025Q2: 273,151 shares; 2025Q3: 273,151 shares; 2025Q4: 273,151 shares; 2026Q1: 738,151 shares 738,151$15.3M5.65%+465,000Timeline
EIKNEIKON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,318,983 shares 1,318,983$14M5.15%newTimeline
LYELLYELL IMMUNOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 406,652 shares; 2025Q3: 477,078 shares; 2025Q4: 477,078 shares; 2026Q1: 477,078 shares 477,078$9.57M3.53%0Timeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 194,125 shares 194,125$5.48M2.02%newTimeline
NRIXNURIX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 265,000 shares 265,000$4.11M1.52%newTimeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 345,191 shares; 2025Q2: 345,191 shares; 2025Q3: 86,291 shares; 2025Q4: 86,291 shares; 2026Q1: 25,905 shares 25,905$773K0.29%-60,386Timeline

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
NTRANATERA INC67,356$15.4Mshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-062464 base2026-05-15acceptance time not in the bulk data set