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Foresite Capital Management V, LLC

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13F filer, CIK 1792206, WEST HOLLYWOOD, CA

Foresite Capital Management V, LLC reported $164,402,957 across 7 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-015410

Period
2025-12-31
Reported value
$164M
Holdings
7
Top 10 weight
100%
New
1
Sold out
0

Largest buys vs the previous quarter

SecurityShares changeApprox. value
NTRAnew+67,356$15.4M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

None.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001104659-26-015410, largest first. % of portfolio is the value over $164,402,957, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,584,889 shares; 2024Q4: 5,779,348 shares; 2025Q1: 5,779,348 shares; 2025Q2: 5,779,348 shares; 2025Q3: 5,779,348 shares; 2025Q4: 5,779,348 shares 5,779,348$56.4M34.31%0Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 692,550 shares; 2024Q4: 692,550 shares; 2025Q1: 859,050 shares; 2025Q2: 1,004,050 shares; 2025Q3: 1,004,050 shares; 2025Q4: 1,004,050 shares 1,004,050$41.7M25.36%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 299,069 shares; 2024Q4: 299,069 shares; 2025Q1: 299,069 shares; 2025Q2: 299,069 shares; 2025Q3: 299,069 shares; 2025Q4: 299,069 shares 299,069$23.7M14.45%0Timeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 67,356 shares 67,356$15.4M9.39%newTimeline
LYELLYELL IMMUNOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 406,652 shares; 2025Q3: 477,078 shares; 2025Q4: 477,078 shares 477,078$14.7M8.93%0Timeline
HIMSHIMS & HERS HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,759,314 shares; 2024Q4: 939,860 shares; 2025Q1: 273,151 shares; 2025Q2: 273,151 shares; 2025Q3: 273,151 shares; 2025Q4: 273,151 shares 273,151$8.87M5.39%0Timeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 345,191 shares; 2025Q2: 345,191 shares; 2025Q3: 86,291 shares; 2025Q4: 86,291 shares 86,291$3.58M2.17%0Timeline

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-015410 base2026-02-17acceptance time not in the bulk data set