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Catalio Capital Management, LP

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13F filer, CIK 1958125, NEW YORK, NY

Catalio Capital Management, LP reported $476,910,569 across 40 holdings for the quarter ended 2025-06-30, in a 13F-HR filed 2025-08-14. Its ten largest share positions make up 62.53% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001958125-25-000007

Period
2025-06-30
Reported value
$477M
Holdings
40
Top 10 weight
62.53%
New
13
Sold out
10

Part of the filer group Catalio Capital Management, LP

  • Catalio Capital GP, LLC
  • Petrocheilos George C
  • Vogelstein R Jacob
How groups are built

Stakes and trades reported after 2025-06-30

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • FRACTYL HEALTH, INC.: 13G 736,807 shares, 5.6% of the class, 13G filed 2026-10-13, 0001958125-26-000008
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
GILDnew+226,875$25.2M
BSXnew+229,046$24.6M
LLYadded+30,234$23.6M
SLNOadded+248,982$20.9M
TEVAnew+1,170,372$19.6M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
BDXexited-203,965-$46.7M
SPRINGWORKS THERAPEUTICS INCexited-758,533-$33.5M
VCYTexited-762,225-$22.6M
LIVNexited-381,648-$15M
INSPexited-85,877-$13.7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2025

Share positions as resolved from 13F-HR 0001958125-25-000007, largest first. % of portfolio is the value over $476,910,569, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 23,682 shares; 2025Q2: 53,916 shares 53,916$42M8.81%+30,234Timeline
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 898,458 shares; 2025Q1: 962,883 shares; 2025Q2: 927,711 shares 927,711$40.1M8.4%-35,172Timeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 160,962 shares; 2025Q2: 409,944 shares 409,944$34.3M7.2%+248,982Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 215,587 shares; 2025Q1: 195,523 shares; 2025Q2: 179,926 shares 179,926$31.1M6.51%-15,597Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 36,910 shares; 2025Q1: 36,499 shares; 2025Q2: 56,674 shares 56,674$30.8M6.46%+20,175Timeline
EWEDWARDS LIFESCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 333,144 shares; 2025Q1: 435,588 shares; 2025Q2: 390,932 shares 390,932$30.6M6.41%-44,656Timeline
GILDGILEAD SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 226,875 shares 226,875$25.2M5.27%newTimeline
BSXBOSTON SCIENTIFIC CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 72,925 shares; 2025Q1: not reported; 2025Q2: 229,046 shares 229,046$24.6M5.16%newTimeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 457,587 shares; 2025Q1: 585,812 shares; 2025Q2: 601,439 shares 601,439$19.9M4.17%+15,627Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 1,733,701 shares; 2025Q2: 2,104,512 shares 2,104,512$19.7M4.13%+370,811Timeline
TEVATEVA PHARMACEUTICAL INDS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,170,372 shares 1,170,372$19.6M4.11%newTimeline
CORTCORCEPT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 239,125 shares 239,125$17.6M3.68%newTimeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 97,297 shares 97,297$16.4M3.45%newTimeline
ADPTADAPTIVE BIOTECHNOLOGIES CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 611,639 shares; 2025Q2: 1,396,445 shares 1,396,445$16.3M3.41%+784,806Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 763,471 shares; 2025Q1: 763,471 shares; 2025Q2: 746,527 shares 746,527$13.9M2.92%-16,944Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 569,395 shares; 2025Q1: 704,864 shares; 2025Q2: 670,575 shares 670,575$13.9M2.92%-34,289Timeline
ADMAADMA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 512,724 shares; 2025Q1: not reported; 2025Q2: 569,704 shares 569,704$10.4M2.18%newTimeline
HALOHALOZYME THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 191,529 shares 191,529$9.96M2.09%newTimeline
RAREULTRAGENYX PHARMACEUTICAL INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 213,402 shares 213,402$7.76M1.63%newTimeline
MLTXMOONLAKE IMMUNOTHERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 114,616 shares; 2025Q2: 162,596 shares 162,596$7.67M1.61%+47,980Timeline
PHATPHATHOM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 672,290 shares 672,290$6.45M1.35%newTimeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 901,973 shares; 2025Q1: 830,325 shares; 2025Q2: 417,443 shares 417,443$5.82M1.22%-412,882Timeline
WGSGENEDX HOLDINGS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 61,507 shares 61,507$5.68M1.19%newTimeline
TARAPROTARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 1,088,691 shares; 2025Q1: 1,088,691 shares; 2025Q2: 1,626,370 shares 1,626,370$4.93M1.03%+537,679Timeline
OMOUTSET MED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 166,666 shares; 2025Q2: 166,666 shares 166,666$3.2M0.67%0Timeline
SEPNSEPTERNA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 1,024,245 shares; 2025Q1: 1,024,245 shares; 2025Q2: 294,360 shares 294,360$3.11M0.65%-729,885Timeline
REPLREPLIMUNE GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 355,640 shares; 2025Q2: 330,337 shares 330,337$3.07M0.64%-25,303Timeline
ZBIOZENAS BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 187,184 shares; 2025Q1: 295,148 shares; 2025Q2: 215,314 shares 215,314$2.09M0.44%-79,834Timeline
VIRVIR BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 611,608 shares; 2025Q2: 388,303 shares 388,303$1.96M0.41%-223,305Timeline
KYTXKYVERNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 586,909 shares; 2025Q1: 586,909 shares; 2025Q2: 586,909 shares 586,909$1.8M0.38%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 179,815 shares; 2025Q1: not reported; 2025Q2: 30,661 shares 30,661$1.62M0.34%newTimeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 202,139 shares; 2025Q2: 188,304 shares 188,304$1.3M0.27%-13,835Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 97,800 shares 97,800$909K0.19%newTimeline
MGXMETAGENOMI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 528,993 shares; 2025Q1: 528,993 shares; 2025Q2: 528,993 shares 528,993$783K0.16%0Timeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: 155,622 shares; 2025Q2: 146,013 shares 146,013$629K0.13%-9,609Timeline
HYPRHYPERFINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 760,035 shares; 2025Q1: 760,035 shares; 2025Q2: 760,035 shares 760,035$547K0.11%0Timeline
Mersana Therapeutics IncMersana Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 1,705,036 shares; 2025Q1: 1,705,036 shares; 2025Q2: 1,567,413 shares 1,567,413$464K0.1%-137,623
ATAIBECKLEY INCATAIBECKLEY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 196,858 shares; 2025Q1: 196,858 shares; 2025Q2: 196,858 shares 196,858$431K0.09%0
GUTSFRACTYL HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 214,236 shares; 2025Q1: 214,236 shares; 2025Q2: 214,236 shares 214,236$347K0.07%0Timeline
FTHFAETH THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 14,718 shares 14,718$126K0.03%newTimeline

Sold out in Q2 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
BDXBECTON DICKINSON & CO203,965$46.7Mshares
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INC758,533$33.5Mshares
VCYTVERACYTE INC762,225$22.6Mshares
LIVNLIVANOVA PLC381,648$15Mshares
INSPINSPIRE MED SYS INC85,877$13.7Mshares
REGNREGENERON PHARMACEUTICALS12,261$7.78Mshares
SOLENO THERAPEUTICS INCSOLENO THERAPEUTICS INC100,000$6.5Mcall
KROSKEROS THERAPEUTICS INC389,384$3.97Mshares
ARCUTIS BIOTHERAPEUTICS INCARCUTIS BIOTHERAPEUTICS INC100,000$1.25Mput
SENSEI BIOTHERAPEUTICS INCSENSEI BIOTHERAPEUTICS INC294,374$116Kshares

How Q2 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001958125-25-000007 base2025-08-14acceptance time not in the bulk data set