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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,632 managers (1,675 13F filers) reported a position in VRTX shares at 2025-12-31, 241,593,776 shares in all. 163 filers opened a position and 101 filers sold out during the quarter.

Managers
1,632
13F filers
1,675
New
163
Added
620
Reduced
566
Sold out
101
Shares held by filers
241,593,776

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.590$267K<0.01%+8513F-HRTimelineGroup
Signet Private Wealth LLC589$267K0.26%13F-HRTimeline
KELLY LAWRENCE W & ASSOCIATES INC/CA585$265K0.06%013F-HRTimeline
MBL Wealth, LLC584$265K0.02%new13F-HRTimeline
Capital Asset Advisory Services LLC565$265K0.01%new13F-HRTimeline
CAMBIENT FAMILY OFFICE, LLC582$264K0.04%13F-HRTimeline
Relyea Zuckerberg Hanson LLC576$261K0.03%+2213F-HRTimeline
180 WEALTH ADVISORS, LLC575$261K0.03%new13F-HRTimeline
MEYER HANDELMAN CO575$261K0.01%new13F-HRTimeline
Kingsview Wealth Management, LLC574$260K<0.01%+1313F-HRTimeline
WHITTIER TRUST CO OF NEVADA INC553$259K0.01%-10413F-HRTimeline
McAdam, LLC569$258K0.01%-17113F-HRTimeline
ANCHYRA PARTNERS LLC569$258K0.08%13F-HRTimeline
AGF MANAGEMENT LTDin group AGF MANAGEMENT LTD568$258K<0.01%-7,16713F-HRTimelineGroup
Elyxium Wealth, LLC568$257K0.07%+4613F-HRTimeline
Regent Peak Wealth Advisors LLC567$257K0.05%+3113F-HRTimeline
Asset Allocation & Management Company, …567$257K0.1%013F-HRTimeline
AXXCESS WEALTH MANAGEMENT, LLC565$256K<0.01%new13F-HR/ATimeline
Opal Wealth Advisors, LLC561$254K0.07%new13F-HRTimeline
Catalyst Funds Management Pty Ltd560$254K0.06%new13F-HRTimeline
Empower Advisory Group, LLCin group Empower Annuity Insurance Co …558$253K<0.01%-2913F-HRTimelineGroup
Quent Capital, LLC557$253K0.02%+5613F-HRTimeline
Berman McAleer LLC557$253K0.03%-4013F-HRTimeline
MONETARY MANAGEMENT GROUP INC555$252K0.06%013F-HRTimeline
Nvest Financial, LLC554$251K0.1%+513F-HRTimeline
Hanson & Doremus Investment Management554$251K0.03%+2013F-HRTimeline
Pinion Investment Advisors, LLC552$250K0.06%-7813F-HRTimeline
Quantum Portfolio Management LLC550$249K0.11%013F-HRTimeline
Fort Point Capital Partners LLC566$248K0.03%-2113F-HRTimeline
Confluence Wealth Services, Inc.545$247K0.01%+2113F-HRTimeline
SG Trading Solutions, LLC544$247K0.06%13F-HRTimeline
Beacon Financial Advisory LLC542$246K0.06%new13F-HRTimeline
Cladis Investment Advisory, LLC542$246K0.13%new13F-HRTimeline
Blackhawk Capital Partners, LLC541$245K0.09%-613F-HRTimeline
PRIVATE TRUST CO NA540$245K0.02%+813F-HRTimeline
Tillman Hartley LLC540$245K0.06%+413F-HRTimeline
Banque Transatlantique SAin group Banque Transatlantique SA539$244K0.01%-7513F-HR/ATimelineGroup
Brookstone Capital Managementin group Brookstone Capital Management535$243K<0.01%-413F-HRTimelineGroup
Collaborative Wealth Managment Inc.534$242K0.09%new13F-HRTimeline
PURSUIT WEALTH STRATEGIES, LLC534$242K0.34%13F-HRTimeline
CIDEL ASSET MANAGEMENT INC532$241K0.02%new13F-HRTimeline
JGP Global Gestao de Recursos Ltda.532$241K0.14%-5413F-HRTimeline
Sustainable Insight Capital Management,…531$241K0.08%new13F-HRTimeline
Elm Partners Management LLC531$241K0.01%+113F-HR/ATimeline
Clark Capital Management Group, Inc.530$240K<0.01%-4213F-HRTimeline
Vanguard Capital Wealth Advisors530$240K0.19%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
BLB&B Advisors, LLC528$239K0.01%+713F-HRTimeline
Virtue Capital Management, LLC529$239K0.04%new13F-HR/ATimeline
GM Advisory Group, LLC527$239K0.01%new13F-HRTimeline
Focus Financial Network, Inc.524$238K0.01%-1513F-HRTimeline
BRIAN LOW FINANCIAL GROUP, LLC523$237K0.17%new13F-HRTimeline
CoreCap Advisors, LLC520$236K0.01%+3013F-HRTimeline
TRITONPOINT WEALTH, LLCin group TritonPoint Partners, LLC517$234K0.02%-3113F-HRTimelineGroup
VICTORY FINANCIAL GROUP, LLC516$234K0.03%new13F-HRTimeline
FIRST FOUNDATION ADVISORSin group FIRST FOUNDATION ADVISORS515$233K0.01%013F-HRTimelineGroup
Vilga Financial Planning LLC515$233K0.22%13F-HRTimeline
Heartwood Wealth Advisors LLC511$232K0.02%-2113F-HRTimeline
Ethos Financial Group, LLC511$232K0.02%new13F-HRTimeline
MORRIS FINANCIAL CONCEPTS, INC.507$230K0.08%-413F-HRTimeline
Five Oceans Advisors507$230K0.08%new13F-HRTimeline
Sound Income Strategies, LLC520$230K0.01%+1413F-HRTimeline
Miller Capital Partners, Inc.505$229K0.12%13F-HRTimeline
Crewe Advisors LLC504$228K0.02%+313F-HRTimeline
Warren Street Wealth Advisors, LLC503$228K0.07%-5613F-HRTimeline
US Asset Management LLC503$228K0.19%new13F-HRTimeline
Smithfield Trust Co503$228K0.01%013F-HRTimeline
Forvis Mazars Wealth Advisors, LLC502$228K<0.01%-9013F-HRTimeline
SPIREPOINT PRIVATE CLIENT, LLC502$228K0.02%new13F-HRTimeline
Symphony Financial, Ltd. Co.501$227K0.03%-17113F-HRTimeline
Mengis Capital Management, Inc.500$227K0.04%new13F-HRTimeline
Arlington Financial Advisors, LLC500$227K0.03%new13F-HRTimeline
McHugh Group, LLC500$227K0.13%new13F-HRTimeline
TRUST POINT INC.500$227K0.02%new13F-HRTimeline
HMS Capital Management, LLC497$225K0.09%-44813F-HRTimeline
EQUITABLE TRUST CO496$225K0.01%new13F-HRTimeline
Anchor Investment Management, LLC495$224K0.02%-1,89213F-HRTimeline
Putney Financial Group LLC495$224K0.21%-7913F-HRTimeline
Chatterton & Associates Inc.495$224K0.19%13F-HRTimeline
SALEM INVESTMENT COUNSELORS INC494$224K0.01%+13513F-HRTimeline
Bryn Mawr Trust Advisors, LLC494$224K0.01%new13F-HRTimeline
Drucker Wealth 3.0, LLC494$224K0.04%new13F-HRTimeline
HARBOUR INVESTMENTS, INC.493$224K<0.01%+2913F-HRTimeline
Mesirow Financial Investment Management…493$224K<0.01%-18613F-HRTimeline
Joel Isaacson & Co., LLC492$223K0.01%new13F-HRTimeline
Onyx Bridge Wealth Group LLC491$223K0.02%new13F-HRTimeline
SeaCrest Wealth Management, LLC459$222K0.02%new13F-HRTimeline
SevenBridge Financial Group, LLC465$222K0.04%-1513F-HRTimeline
Investment Advisory Group, LLC489$222K0.06%-12013F-HRTimeline
Beaumont Financial Advisors, LLC486$220K0.01%new13F-HRTimeline
SHP Wealth Management486$220K0.02%13F-HRTimeline
Commonwealth Financial Services, LLC485$220K0.04%new13F-HRTimeline
HERITAGE INVESTORS MANAGEMENT CORP486$220K0.01%new13F-HRTimeline
Covestor Ltd484$220K0.12%+26213F-HRTimeline
Epoch Investment Partners, Inc.485$220K<0.01%-14913F-HRTimeline
Boston Trust Walden Corpin group Boston Trust Walden Corp485$220K<0.01%new13F-HRTimelineGroup
Loudon Investment Management, LLC485$220K0.11%new13F-HRTimeline
Stanley-Laman Group, Ltd.485$220K0.03%new13F-HRTimeline
Capstone Capital Management Ltd484$219K0.21%13F-HRTimeline
BOURGEON CAPITAL MANAGEMENT LLC483$219K0.04%new13F-HRTimeline
ADIRONDACK TRUST CO483$219K0.07%+2613F-HRTimeline
Washington Trust Advisors, Inc.483$219K0.02%+13413F-HRTimeline
Bank Pictet & Cie (Europe) AG482$219K<0.01%new13F-HRTimeline
LaFleur & Godfrey LLC482$219K0.03%new13F-HRTimeline
Impact Partnership Wealth, LLC480$218K0.03%new13F-HRTimeline
JUPITER ASSET MANAGEMENT LTDin group JUPITER ASSET MANAGEMENT LTD480$218K<0.01%-65,13913F-HRTimelineGroup
Trinity Legacy Partners, LLC480$218K0.05%013F-HRTimeline
Ponta Wealth Partners, LLC479$217K0.2%13F-HRTimeline
GUERRA PAN ADVISORS, LLC478$217K0.13%new13F-HRTimeline
PATHWAY WEALTH MANAGEMENT LLC475$215K0.2%13F-HRTimeline
Inscription Capital, LLC473$214K0.02%-14713F-HRTimeline
Fieldview Capital Management, LLC473$214K0.04%new13F-HRTimeline
Sage Capital Management, LLC472$214K0.1%new13F-HRTimeline
GREAT LAKES ADVISORS, LLC471$214K<0.01%new13F-HRTimeline
Retirement Planning Group, LLC470$213K0.01%new13F-HRTimeline
Safe Harbor Wealth Advisors, LLC457$213K0.21%13F-HRTimeline
United Advisor Group, LLC468$212K0.03%-27013F-HRTimeline
Klingman & Associates, LLC465$211K0.01%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC463$210K0.02%new13F-HRTimeline
Cornerstone Wealth Group, LLC463$210K0.01%new13F-HRTimeline
Rothschild Wealth LLC461$209K0.02%new13F-HR/ATimeline
Wall Street Financial Group, Inc.461$209K0.15%new13F-HRTimeline
S Harris Financial Group, LLC461$209K0.2%13F-HRTimeline
LIBERTY WEALTH MANAGEMENT LLC459$208K0.03%new13F-HRTimeline
Hutchens & Kramer Investment Management…457$207K0.07%new13F-HRTimeline
PLANNING ALTERNATIVES LTD /ADV454$206K0.03%new13F-HRTimeline
MAINSAIL ASSET MANAGEMENT, LLC454$206K0.09%new13F-HRTimeline
Ledyard National Bank453$205K0.02%new13F-HRTimeline
PKS Advisory Services, LLC453$205K0.05%new13F-HRTimeline
Englebert Financial Advisers, LLC453$205K0.24%13F-HRTimeline
Fielder Capital Group LLC452$205K0.04%new13F-HRTimeline
Hansen & Associates Financial Group, In…441$204K0.11%new13F-HRTimeline
Cornerstone Planning, LLC450$204K0.05%13F-HRTimeline
Paragon Private Wealth Management, LLC450$204K0.06%new13F-HRTimeline
PFW Advisors LLC450$204K0.06%new13F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.449$204K0.03%-16713F-HRTimeline
BLALOCK WILLIAMS, LLC444$202K0.16%new13F-HRTimeline
Global Trust Asset Management, LLC430$195K0.08%-15613F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…410$186K0.01%-8813F-HRTimeline
Manchester Capital Management LLC405$184K0.02%+14113F-HRTimeline
Private Wealth Asset Management, LLC402$182K0.02%013F-HRTimeline
Deseret Mutual Benefit Administrators396$180K0.08%+1813F-HRTimeline
CVA Family Office, LLC393$178K0.02%+513F-HRTimeline
ROTHSCHILD INVESTMENT LLC387$175K0.01%+4113F-HRTimeline
Goodman Advisory Group, LLC379$172K0.04%013F-HRTimeline
LRI Investments, LLC374$169K0.01%+513F-HRTimeline
Oslo Pensjonsforsikring AS373$169K0.02%013F-HRTimeline
Johnson Financial Group, Inc.in group Johnson Financial Group, Inc.367$166K0.01%-28113F-HRTimelineGroup
Keating Financial Advisory Services, In…367$166K0.02%13F-HRTimeline
Wealth Enhancement Trust Services, Inc.360$163K0.02%13F-HRTimeline
DV EQUITIES, LLC358$162K0.03%13F-HRTimeline
PARADIGM ASSET MANAGEMENT CO LLC350$159K0.04%013F-HRTimeline
BARD ASSOCIATES INC350$159K0.04%new13F-HRTimeline
Addison Advisors LLC326$148K0.03%-613F-HRTimeline
EASTERN BANK322$146K<0.01%-31613F-HRTimeline
Clean Yield Group322$146K0.04%013F-HRTimeline
TFC Financial Management, Inc.307$139K0.02%-113F-HRTimeline
McMillan Office, Inc.300$136K0.02%13F-HRTimeline
GPS Wealth Strategies Group, LLC297$135K0.11%-59913F-HRTimeline
Asset Dedication, LLC294$133K0.01%013F-HRTimeline
Key Financial Inc290$131K0.02%013F-HRTimeline
Tripletail Wealth Management, LLC290$131K0.17%-2013F-HRTimeline
Reflection Asset Management288$131K0.09%13F-HRTimeline
Ritter Daniher Financial Advisory LLC /…282$128K0.02%013F-HRTimeline
Garton & Associates Financial Advisors …278$126K0.07%13F-HRTimeline
Roble, Belko & Company, Inc279$126K0.02%013F-HRTimeline
Hilltop National Bank272$123K0.03%013F-HRTimeline
PEAK6 LLCin group PEAK6 LLC272$123K<0.01%-24,14413F-HR/ATimelineGroup
Root Financial Partners, LLC269$122K0.01%+4613F-HRTimeline
VAN LANSCHOT KEMPEN INVESTMENT MANAGEME…257$117K<0.01%+1613F-HRTimeline
Rossby Financial, LCC256$116K0.04%-713F-HRTimeline
Sankala Group LLC233$116K0.09%13F-HRTimeline
MCF Advisors LLC254$115K0.01%+7113F-HRTimeline
Acumen Wealth Advisors, LLC253$115K0.03%13F-HRTimeline
QVR LLC253$115K0.08%new13F-HRTimeline
Golden State Wealth Management, LLC250$113K0.01%-1513F-HRTimeline
LANARK FINANCIAL, INC.246$112K0.01%+5813F-HRTimeline
TRUST CO OF VERMONT245$111K<0.01%+1413F-HRTimeline
WPG Advisers, LLC245$111K0.08%+913F-HRTimeline
TRUST CO OF TOLEDO NA /OH/244$111K0.01%013F-HRTimeline
TOTH FINANCIAL ADVISORY CORP230$104K0.01%013F-HRTimeline
Colonial Trust Advisorsgroup of 2 filers holding226$103K-67Timeline
Crews Bank & Trust212$96.1K0.01%013F-HRTimeline
Moisand Fitzgerald Tamayo, LLC200$90.7K0.01%013F-HRTimeline
ORG Partners LLC193$87.5K0.02%-5313F-HRTimeline
EDMOND DE ROTHSCHILD HOLDING S.A.in group EDMOND DE ROTHSCHILD HOLDING …191$86.6K<0.01%013F-HRTimelineGroup
MV CAPITAL MANAGEMENT, INC.189$85.7K0.01%+313F-HRTimeline
Rosenberg Matthew Hamilton184$83.4K0.02%+1113F-HRTimeline
VALLEY NATIONAL ADVISERS INC185$83K0.01%013F-HRTimeline
REAP Financial Group, LLC182$82.5K0.02%+2913F-HRTimeline
Cornerstone Financial Management LLC182$82.5K0.08%13F-HR/ATimeline
Westside Investment Management, Inc.179$80.9K0.01%+313F-HRTimeline
1620 INVESTMENT ADVISORS, INC.178$80.8K0.05%013F-HRTimeline
Greenline Wealth Management LLC176$79.7K0.08%13F-HRTimeline
Plante Moran Financial Advisors, LLC174$78.9K<0.01%-4513F-HRTimeline
FARMERS & MERCHANTS INVESTMENTS INCin group FARMERS & MERCHANTS INVESTMEN…170$77.1K<0.01%+413F-HRTimelineGroup
Steigerwald, Gordon & Koch Inc.167$75.7K0.01%013F-HRTimeline
AMERIFLEX GROUP, INC.166$75.3K0.04%-2613F-HRTimeline
Truvestments Capital LLC164$74.4K0.01%-513F-HRTimeline
Clearstead Trust, LLC161$73K0.01%+2913F-HRTimeline
ST GERMAIN D J CO INCin group ST GERMAIN D J CO INC161$73K<0.01%+1613F-HRTimelineGroup