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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,632 managers (1,675 13F filers) reported a position in VRTX shares at 2025-12-31, 241,593,776 shares in all. 163 filers opened a position and 101 filers sold out during the quarter.

Managers
1,632
13F filers
1,675
New
163
Added
620
Reduced
566
Sold out
101
Shares held by filers
241,593,776

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Knuff & Co LLC14,197$6.44M1.9%+1313F-HRTimeline
Allworth Financial LP14,036$6.36M0.03%+11,30613F-HRTimeline
PARK AVENUE SECURITIES LLCin group PARK AVENUE SECURITIES LLC13,807$6.26M0.05%-1,23613F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS13,804$6.26M0.01%+1,73013F-HRTimeline
Sivik Global Healthcare LLC13,770$6.24M3.05%-23013F-HRTimeline
ZIONS BANCORPORATION, NATIONAL ASSOCIAT…13,758$6.24M0.29%+4,12013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC13,716$6.22M0.47%+6,71613F-HR/ATimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC13,685$6.2M0.06%+46313F-HRTimelineGroup
Baader Bank Aktiengesellschaft13,604$6.16M0.51%new13F-HRTimeline
Sequoia Financial Advisors, LLC13,596$6.16M0.03%-38413F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…13,579$6.16M0.15%-44313F-HRTimelineGroup
Beacon Pointe Advisors, LLC13,502$6.12M0.04%+21813F-HRTimeline
Princeton Global Asset Management LLC13,159$5.97M0.97%-20013F-HRTimeline
Federation des caisses Desjardins du Qu…13,016$5.9M0.02%+2,19913F-HRTimeline
Fisher Funds Management LTD12,898$5.86M0.15%013F-HRTimeline
Gulf International Bank (UK) Ltd12,916$5.86M0.19%+3713F-HRTimeline
Maryland State Retirement & Pension Sys…12,846$5.82M0.12%013F-HRTimeline
Capitolis Liquid Global Markets LLCin group CAPITOLIS LIQUID GLOBAL MARKE…12,815$5.81M0.03%new13F-HRTimelineGroup
Metis Global Partners, LLC12,666$5.74M0.14%-75813F-HRTimeline
Compagnie Lombard Odier SCmA12,665$5.74M0.06%+10013F-HRTimeline
New Age Alpha Advisors, LLC12,622$5.72M0.25%-1,31713F-HRTimeline
Kidder Stephen W12,459$5.65M1.59%+16113F-HRTimeline
Andrew Hill Investment Advisors, Inc.12,408$5.63M4.28%+8,69913F-HRTimeline
GREENWOOD CAPITAL ASSOCIATES LLC12,322$5.59M0.61%-49013F-HRTimeline
FIRST HORIZON CORP12,155$5.51M0.25%-1,96613F-HRTimeline
Orion Porfolio Solutions, LLC12,151$5.51M0.04%+1,80313F-HRTimeline
Chicago Capital, LLC12,145$5.51M0.14%-67913F-HRTimeline
UNITED CAPITAL FINANCIAL ADVISORS, LLCin group UNITED CAPITAL FINANCIAL ADVI…12,077$5.48M0.03%+56513F-HRTimelineGroup
EXCHANGE TRADED CONCEPTS, LLC12,025$5.45M0.05%+1,87413F-HRTimeline
Covenant Asset Management, LLC11,889$5.39M1.04%-21513F-HRTimeline
Traynor Capital Management, Inc.11,767$5.33M0.29%-19813F-HRTimeline
Laird Norton Wetherby Trust Company, LLCin group Laird Norton Wetherby Trust C…11,757$5.33M0.11%new13F-HRTimelineGroup
NEW MEXICO EDUCATIONAL RETIREMENT BOARD11,700$5.3M0.16%+10013F-HRTimeline
Lombard Odier Asset Management (Switzer…11,692$5.3M0.23%new13F-HRTimeline
KAYNE ANDERSON RUDNICK INVESTMENT MANAG…11,645$5.28M0.01%+2613F-HRTimeline
Horizon Investments, LLC11,375$5.16M0.07%+2,18113F-HRTimeline
Slow Capital, Inc.11,344$5.14M0.61%+4413F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC11,246$5.1M0.01%-237,02113F-HRTimelineGroup
Siemens Fonds Invest GmbH11,212$5.09M0.27%+47013F-HRTimeline
PKO Investment Management Joint-Stock Co11,200$5.08M0.41%-30013F-HRTimeline
Northwest & Ethical Investments L.P.11,104$5.03M0.11%-4,21113F-HR/ATimeline
BENJAMIN EDWARDS INCin group BENJAMIN EDWARDS INC11,093$5.03M0.06%+59713F-HRTimelineGroup
Banque Cantonale Vaudoisein group Banque Cantonale Vaudoise11,076$5.02M0.18%+95413F-HRTimelineGroup
Vinva Investment Management Ltd10,938$4.96M0.06%+2,30313F-HRTimeline
Cornerstone Advisors, LLC10,700$4.85M0.16%-25,40013F-HRTimeline
Northwest Bancshares, Inc.10,636$4.82M0.93%-1,50213F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd10,623$4.82M0.17%new13F-HRTimelineGroup
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…10,526$4.77M0.04%-7613F-HRTimelineGroup
Generali Investments CEE, investicni sp…10,491$4.76M0.34%013F-HRTimeline
Joseph Group Capital Management10,489$4.76M1.25%+12113F-HRTimeline
Morse Asset Management, Inc10,423$4.73M0.94%+11813F-HRTimeline
Fideuram Asset Management (Ireland) dac9,876$4.72M0.37%13F-HRTimeline
AG2R LA MONDIALE GESTION D'ACTIFS10,375$4.7M0.21%+58713F-HRTimeline
MARK SHEPTOFF FINANCIAL PLANNING, LLC10,246$4.65M2.21%-52513F-HRTimeline
KEYBANK NATIONAL ASSOCIATION/OHin group KEYBANK NATIONAL ASSOCIATION/…10,130$4.59M0.02%+9113F-HRTimelineGroup
SIGMA INVESTMENT COUNSELORS INC10,021$4.54M0.23%-11813F-HRTimeline
Fayez Sarofim & Coin group Fayez Sarofim & Co10,000$4.53M0.01%-5813F-HRTimelineGroup
DIADEMA PARTNERS LP10,000$4.53M2.7%new13F-HRTimeline
DKRT Investments Corp.10,000$4.53M1.28%new13F-HRTimeline
JOURNEY RETIREMENT PLANNING & INVESTMEN…9,892$4.48M0.92%13F-HRTimeline
Campbell & CO Investment Adviser LLC9,858$4.47M0.21%+7,83513F-HRTimeline
Composition Wealth, LLC9,834$4.46M0.06%+75913F-HRTimeline
FIL Ltdin group FIL Ltd9,803$4.44M<0.01%+1,09713F-HRTimelineGroup
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…9,734$4.41M0.05%+6,89513F-HRTimelineGroup
Tema ETFs LLC9,612$4.36M0.34%-3913F-HRTimeline
Cumberland Partners Ltdin group Cumberland Partners Ltd9,607$4.36M0.27%-13713F-HRTimelineGroup
LEVEL FOUR ADVISORY SERVICES, LLCin group LEVEL FOUR ADVISORY SERVICES,…9,553$4.33M0.14%+1,96713F-HRTimelineGroup
GAM Holding AGin group GAM Holding AG9,552$4.33M0.28%-1,46313F-HRTimelineGroup
HOWE & RUSLING INC9,518$4.31M0.29%+16813F-HRTimeline
PARSONS CAPITAL MANAGEMENT INC/RI9,491$4.3M0.24%-39513F-HRTimeline
F/m Investments LLC9,484$4.3M0.16%-28013F-HRTimeline
HB Wealth Management, LLC9,472$4.29M0.03%+79213F-HRTimeline
Privium Fund Management B.V.9,355$4.24M0.78%+1,05513F-HRTimeline
TOKIO MARINE ASSET MANAGEMENT CO LTDin group TOKIO MARINE HOLDINGS, INC.9,324$4.23M0.15%+36813F-HRTimelineGroup
Howard Capital Management, LLC9,274$4.2M0.05%+36013F-HRTimeline
Peloton Wealth Strategists9,040$4.1M1.59%+1,16513F-HRTimeline
E. Ohman J:or Asset Management AB9,023$4.09M0.1%-1,49713F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…9,000$4.08M0.14%+6,50013F-HRTimelineGroup
Merit Financial Group, LLC8,967$4.07M0.03%+2,88013F-HRTimeline
EP Wealth Advisors, LLC8,946$4.06M0.02%13F-HRTimeline
LITTLE HOUSE CAPITAL LLC8,939$4.05M1.02%-82113F-HRTimeline
Sepio Capital, LP8,865$4.02M0.22%-19813F-HRTimeline
North Dakota State Investment Board8,821$4M0.15%13F-HRTimeline
Strategic Advisors LLC8,775$3.98M0.62%-7913F-HRTimeline
Davidson Capital Management Inc.8,759$3.97M0.86%-3613F-HRTimeline
Bensler, LLC8,746$3.96M0.4%-9013F-HRTimeline
Empirical Finance, LLC8,711$3.95M0.19%-78213F-HRTimeline
Private Advisor Group, LLC8,694$3.94M0.02%+1,33013F-HRTimeline
Verition Fund Management LLC8,406$3.81M0.02%-3,13813F-HRTimeline
Linden Thomas Advisory Services, LLC8,405$3.81M0.39%-1413F-HRTimeline
NewEdge Wealth, LLC8,402$3.81M0.04%+2,75413F-HRTimeline
ASHFORD CAPITAL MANAGEMENT INC8,245$3.74M0.42%013F-HRTimeline
CIBC WORLD MARKET INC.8,133$3.69M0.01%-10313F-HRTimeline
SUMITOMO LIFE INSURANCE CO8,126$3.68M0.1%+1,03313F-HRTimeline
SageGuard Financial Group, LLC8,103$3.67M0.58%13F-HRTimeline
COMMERZBANK AKTIENGESELLSCHAFT /FI8,091$3.67M0.07%-48413F-HRTimeline
SECTORAL ASSET MANAGEMENT INC8,005$3.63M2.91%+29013F-HRTimeline
Crestwood Advisors Group, LLC8,003$3.63M0.06%-1,14813F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP7,995$3.62M<0.01%+87113F-HRTimelineGroup
GAMCO Investors (Gabelli)group of 2 filers holding7,984$3.62M-7,530Timeline
J.P. Marvel Investment Advisors, LLC7,855$3.56M0.49%013F-HRTimeline
Notis-McConarty Edward7,854$3.56M1.65%+5013F-HRTimeline
BALDWIN WEALTH PARTNERS LLC/MA7,824$3.55M0.23%-12013F-HRTimeline
Vestmark Advisory Solutions, Inc.7,822$3.55M0.05%-1,60613F-HRTimeline
BROWN ADVISORY INCin group BROWN ADVISORY INC7,774$3.52M<0.01%-32013F-HRTimelineGroup
JOHNSON INVESTMENT COUNSEL INC7,726$3.5M0.03%-413F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC7,592$3.44M0.01%-86713F-HRTimelineGroup
Transamerica Financial Advisors, LLCin group Transamerica Financial Adviso…7,584$3.44M0.29%-13113F-HRTimelineGroup
Cresset Asset Management, LLC7,555$3.43M0.01%-3713F-HRTimeline
Graphene Investments SAS7,500$3.4M2.13%-80013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd7,442$3.37M0.04%-29813F-HRTimelineGroup
EagleClaw Capital Managment, LLC7,385$3.35M0.48%013F-HRTimeline
CENTRAL TRUST Co7,363$3.34M0.07%-1,03013F-HRTimeline
CWM, LLCin group CWM, LLC7,343$3.33M0.01%+1,40113F-HRTimelineGroup
Stenger Family Office, LLC7,323$3.32M0.69%-3,39813F-HRTimeline
Codex Capital Asset Management L.L.C.7,320$3.32M1.21%+7013F-HRTimeline
SummitTX Capital, L.P.7,231$3.28M0.1%-72413F-HRTimeline
Freemont Management S.A.7,200$3.26M0.64%+4,80013F-HRTimeline
HANTZ FINANCIAL SERVICES, INC.7,191$3.26M0.05%+96113F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
BNP PARIBASin group BNP PARIBAS7,139$3.24M0.09%+1,79813F-HRTimelineGroup
Dempze Nancy E7,058$3.2M1.67%-19413F-HRTimeline
Elefante Mark B7,015$3.18M1.95%+35213F-HRTimeline
CHOREO, LLC7,008$3.18M0.04%+1,15413F-HRTimeline
Glenview Trust Co7,005$3.18M0.05%+2413F-HRTimeline
COMMERCE BANKin group COMMERCE BANK6,999$3.17M0.02%+6713F-HRTimelineGroup
Delaney Dennis R6,969$3.16M1.59%-7913F-HRTimeline
Associated Banc-Corpin group Associated Banc-Corp6,947$3.15M0.08%-17113F-HRTimelineGroup
SECURIAN ASSET MANAGEMENT, INC6,899$3.13M0.12%-5,41713F-HRTimeline
NORTH STAR ASSET MANAGEMENT INC6,859$3.11M0.13%-2413F-HRTimeline
RDA Financial Network6,839$3.1M0.75%+13013F-HRTimeline
Wahed Invest LLC6,771$3.07M0.4%-2913F-HRTimeline
Edgestream Partners, L.P.6,703$3.04M0.09%-1,04313F-HRTimeline
THOMPSON SIEGEL & WALMSLEY LLC6,698$3.04M0.05%-10513F-HRTimeline
Meeder Advisory Services, Inc.group of 2 filers holding6,690$3.03M+722Timeline
Kintegral Advisory, LLCin group Kintegral Advisory, LLC6,681$3.03M0.26%-18313F-HRTimelineGroup
LEAVELL INVESTMENT MANAGEMENT, INC.6,645$3.01M0.13%-34013F-HRTimeline
CHANNEL WEALTH LLC6,606$2.99M0.76%-3,95313F-HRTimeline
Vision Capital Management, Inc.6,595$2.99M0.36%+2913F-HRTimeline
Compound Planning, Inc.6,541$2.97M0.09%+4,15713F-HRTimeline
Baird Financial Group, Inc.in group Baird Financial Group, Inc.6,511$2.95M<0.01%-65913F-HRTimelineGroup
CONDOR CAPITAL MANAGEMENT6,487$2.94M0.24%-2013F-HRTimeline
Canada Post Corp Registered Pension Plan6,474$2.94M0.11%+2,42013F-HRTimeline
CERTUITY, LLC6,439$2.92M0.18%+94113F-HRTimeline
Boomfish Wealth Group, LLC6,410$2.91M1.55%-23713F-HRTimeline
South Dakota Investment Council6,400$2.9M0.06%-48013F-HRTimeline
OneDigital Investment Advisors LLC6,392$2.9M0.03%+4,89813F-HRTimeline
Amova Asset Management Americas, Inc.in group Amova Asset Management Americ…6,314$2.86M0.03%-58813F-HRTimelineGroup
Westview Management dba Westview Invest…6,284$2.85M1.36%13F-HRTimeline
MCCARTER PRIVATE WEALTH SERVICES LLC6,237$2.83M1.27%+18813F-HRTimeline
First National Bank of Mount Dora, Trus…6,212$2.82M0.62%+3713F-HRTimeline
GRIFFIN ASSET MANAGEMENT, INC.6,195$2.81M0.3%-2513F-HRTimeline
Kovack Advisors, Inc.6,191$2.81M0.13%+5,04413F-HR/ATimeline
Aureus Asset Management, LLC6,142$2.78M0.18%+4,32413F-HRTimeline
UNIVEST FINANCIAL Corpin group UNIVEST FINANCIAL Corp6,097$2.76M0.15%-1,26713F-HRTimelineGroup
HighPoint Advisor Group LLC6,089$2.76M0.06%+1,58513F-HRTimeline
Perigon Wealth Management, LLC6,044$2.74M0.05%-6413F-HRTimeline
HALL LAURIE J TRUSTEE6,030$2.73M0.91%+8013F-HRTimeline
Freedom Day Solutions, LLC6,027$2.73M0.74%+21313F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC6,002$2.72M0.04%-40413F-HRTimeline
Cohen Klingenstein LLC6,000$2.72M0.08%013F-HRTimeline
DCF Advisers, LLC6,000$2.72M0.9%new13F-HRTimeline
Plato Investment Management Ltd5,935$2.7M0.18%-9113F-HRTimeline
Harbour Capital Advisors, LLC5,933$2.68M0.55%-24813F-HRTimeline
BOKF, NAin group BOKF, NA5,867$2.66M0.04%-1,17113F-HRTimelineGroup
Illumine Investment Management, LLC5,820$2.64M1.92%-613F-HRTimeline
RMR Wealth Builders5,789$2.62M0.21%+46613F-HRTimeline
Nemes Rush Group LLC5,737$2.6M0.24%-1313F-HRTimeline
TD Waterhouse Canada Inc.5,731$2.6M0.02%+13413F-HRTimeline
GAMMA Investing LLC5,714$2.59M0.13%+1,08213F-HRTimeline
TUDOR INVESTMENT CORP ET AL5,641$2.56M0.01%-45,73313F-HRTimeline
Venturi Wealth Management, LLC5,630$2.55M0.11%-15813F-HRTimeline
V-Square Quantitative Management LLC5,624$2.55M0.27%new13F-HRTimeline
WEDBUSH SECURITIES INC5,561$2.52M0.07%-58913F-HRTimeline
MASTERINVEST Kapitalanlage GmbH5,544$2.52M0.24%013F-HRTimeline
WIMMER ASSOCIATES 1, LLC5,526$2.51M1.16%+7113F-HRTimeline
BLI - Banque de Luxembourg Investments5,500$2.5M0.07%-70013F-HRTimeline
Ascent Group, LLCin group Ascent Group, LLC5,495$2.49M0.09%-1,12413F-HRTimelineGroup
Mediolanum International Funds Ltd5,487$2.49M0.02%-3,05713F-HRTimeline
BURNEY CO/5,468$2.48M0.08%-1,16313F-HRTimeline
Highview Capital Management LLC/DE/5,409$2.45M0.87%-29413F-HRTimeline
Cooper Financial Group5,341$2.42M0.26%+3,02113F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA5,339$2.42M0.01%13F-HRTimelineGroup
SIGNATUREFD, LLC5,305$2.41M0.04%+20213F-HRTimeline
Ballentine Partners, LLC5,290$2.4M0.03%+20013F-HRTimeline
NWAM LLC5,038$2.4M0.13%-3913F-HRTimeline
Vise Technologies, Inc.5,259$2.38M0.05%+1,03613F-HRTimeline
Wealthcare Advisory Partners LLCin group Wealthcare Advisory Partners …5,259$2.38M0.05%+13013F-HRTimelineGroup
D.A. DAVIDSON & CO.5,251$2.38M0.01%+15413F-HRTimeline
BAMCO INC /NY/in group Baron Capital5,200$2.36M0.01%013F-HRTimelineGroup
Parallel Advisors, LLC5,189$2.35M0.04%+13413F-HRTimeline
Sand Hill Global Advisors, LLC5,176$2.35M0.08%-1,55013F-HRTimeline
SCOTIA CAPITAL INC.5,165$2.34M0.01%-75613F-HRTimeline
Te Ahumairangi Investment Management Ltd5,135$2.33M0.42%-59013F-HRTimeline
HAGER INVESTMENT MANAGEMENT SERVICES, L…5,084$2.3M1.26%-18813F-HRTimeline
Westerkirk Capital Inc.5,071$2.3M0.22%+42913F-HRTimeline
Machina Capital S.A.S.5,064$2.3M0.44%-6,10313F-HRTimeline
Summit Trail Advisors, LLC5,057$2.29M0.04%-42713F-HRTimeline
LEGACY CAPITAL WEALTH MANAGEMENT, LLC5,043$2.29M1.38%13F-HRTimeline
Leonteq Securities AG5,026$2.28M0.12%-2,00213F-HRTimeline
Central Pacific Bank - Trust Division5,026$2.28M0.28%+2413F-HRTimeline