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Disclosery

SPRO SPERO THERAPEUTICS INC

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COM (common), issuer CIK 1701108

45 managers (45 13F filers) reported a position in SPRO shares at 2025-06-30, 11,078,704 shares in all. 16 filers opened a position and 10 filers sold out during the quarter.

Managers
45
13F filers
45
New
16
Added
9
Reduced
9
Sold out
10
Shares held by filers
11,078,704

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Pfizer Inc2,362,348$6.85M1.19%013F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC1,950,381$5.66M<0.01%+186,76113F-HRTimelineGroup
Anson Funds Management LPin group Anson Funds Management LP1,615,469$4.68M0.86%-2,183,46313F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.889,979$2.58M0.12%013F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC832,165$2.41M<0.01%-138,74213F-HRTimeline
Schonfeld Strategic Advisors LLC510,834$1.48M0.01%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC510,699$1.48M<0.01%-14,17013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.434,768$1.26M<0.01%-47,31413F-HRTimelineGroup
MONIMUS CAPITAL MANAGEMENT, LP310,908$902K0.72%013F-HRTimeline
Informed Momentum Co LLC239,140$694K0.11%new13F-HRTimeline
Stonepine Capital Management, LLC156,888$455K0.45%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP153,451$445K<0.01%+4,54013F-HRTimelineGroup
Ionic Capital Management LLC150,000$435K0.49%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC143,917$417K0.07%-657,36013F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC114,800$333K0.01%-40,00013F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC112,889$327K<0.01%-758,32313F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC103,786$301K<0.01%+42,47013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP100,831$292K<0.01%-9313F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…69,814$202K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd34,551$100K<0.01%new13F-HRTimelineGroup
Capital Asset Advisory Services LLC32,548$94.4K<0.01%new13F-HRTimeline
AXXCESS WEALTH MANAGEMENT, LLC32,548$94.4K<0.01%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd31,205$90.5K<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC30,322$87K<0.01%+25,22413F-HRTimeline
Three Seasons Wealth, LLC30,000$87K0.01%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co28,565$82.8K<0.01%013F-HRTimelineGroup
Cubist Systematic Strategies, LLC27,140$78.7K<0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.14,968$43.4K<0.01%new13F-HRTimelineGroup
Texas Yale Capital Corp.10,000$29K<0.01%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY9,221$26.7K<0.01%+2,25013F-HRTimelineGroup
GROUP ONE TRADING LLC8,239$23.9K<0.01%new13F-HRTimeline
UBS Group AGin group UBS Group AG8,194$23.8K<0.01%+5,36813F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,739$17K<0.01%new13F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/5,633$16.3K<0.01%+6813F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC3,082$8.94K<0.01%new13F-HRTimelineGroup
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.2,000$5.8K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…603$1.75K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.290$841<0.01%new13F-HR/ATimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO236$684<0.01%-60,58113F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN200$580<0.01%013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\151$438<0.01%013F-HRTimelineGroup
NewEdge Advisors, LLC100$290<0.01%013F-HRTimeline
SBI Securities Co., Ltd.62$180<0.01%+213F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS40$116<0.01%+2813F-HRTimelineGroup
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.