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Disclosery

SPRO SPERO THERAPEUTICS INC

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COM (common), issuer CIK 1701108

51 managers (51 13F filers) reported a position in SPRO shares at 2024-12-31, 15,679,985 shares in all. 8 filers opened a position and 8 filers sold out during the quarter.

Managers
51
13F filers
51
New
8
Added
13
Reduced
9
Sold out
8
Shares held by filers
15,679,985

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Anson Funds Management LPin group Anson Funds Management LP3,839,886$3.96M0.49%+89,43613F-HRTimelineGroup
Pfizer Inc2,362,348$2.43M0.09%13F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC1,763,620$1.82M<0.01%013F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,105,591$1.14M<0.01%+130,93813F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC1,039,922$1.07M<0.01%-31,93813F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.889,979$917K0.05%013F-HRTimelineGroup
Murchinson Ltd.873,910$900K0.4%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC801,277$825K0.17%+57,81813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.485,352$500K<0.01%+53213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC481,128$496K<0.01%-5913F-HRTimelineGroup
MONIMUS CAPITAL MANAGEMENT, LP310,908$320K0.3%13F-HRTimeline
Atlas Venture Life Science Advisors, LLC305,255$314K0.04%-97,63013F-HRTimeline
MACKENZIE FINANCIAL CORP187,559$193K<0.01%+155,65613F-HR/ATimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC184,800$190K<0.01%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC172,872$178K<0.01%+91,44713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP148,911$153K<0.01%+18,40013F-HRTimelineGroup
DAFNA Capital Management LLC125,000$129K0.03%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP86,447$89K<0.01%-25,05013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO61,624$63.5K<0.01%+61,38813F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC55,051$56.7K<0.01%new13F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC52,869$54.5K<0.01%new13F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC49,200$50.7K<0.01%new13F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC46,046$47K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd30,138$31K<0.01%new13F-HRTimelineGroup
Three Seasons Wealth, LLC30,000$30.9K0.02%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…29,755$30.6K<0.01%-14,46413F-HRTimelineGroup
DLK Investment Management, LLC28,955$29.8K0.01%-2,40013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co28,565$29.4K<0.01%013F-HRTimelineGroup
PFG Investments, LLC24,534$25.3K<0.01%+10,55513F-HRTimeline
HRT FINANCIAL LP14,692$15K<0.01%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP10,003$10.3K<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/10,000$10.3K<0.01%013F-HRTimelineGroup
Texas Yale Capital Corp.10,000$10.3K<0.01%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY6,971$7.18K<0.01%013F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/5,547$5.71K<0.01%-10713F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\5,151$5.31K<0.01%+5,00013F-HRTimelineGroup
SIMPLEX TRADING, LLC5,110$5K<0.01%+4,18913F-HRTimeline
FMR LLCin group FMR LLC4,289$4.42K<0.01%+1,15013F-HRTimelineGroup
WR Wealth Planners, LLC2,600$2.68K<0.01%013F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.2,000$2.06K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…929$957<0.01%+66013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.295$304<0.01%013F-HR/ATimelineGroup
SBI Securities Co., Ltd.213$219<0.01%13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN200$206<0.01%013F-HRTimelineGroup
RICHARDS, MERRILL & PETERSON, INC.150$155<0.01%13F-HRTimeline
UBS Group AGin group UBS Group AG141$145<0.01%-17,38813F-HRTimelineGroup
NewEdge Advisors, LLC100$103<0.01%013F-HRTimeline
CoreCap Advisors, LLC50$52<0.01%-14213F-HRTimeline
Federation des caisses Desjardins du Qu…30$31<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS12$12<0.01%013F-HRTimelineGroup
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.